Abstract：
:Image-guided intervention for soft tissue organs depends on the accuracy of deformable registration methods to achieve effective results. While registration techniques based on elastic theory are prevalent, no methods yet exist that can prospectively estimate registration uncertainty to regulate sources and mitigate consequences of localization error in deforming organs. This paper introduces registration uncertainty metrics based on dispersion of strain energy from boundary constraints to predict the proportion of target registration error (TRE) remaining after nonrigid elastic registration. These uncertainty metrics depend on the spatial distribution of intraoperative constraints provided to registration with relation to patient-specific organ geometry. Predictive linear and bivariate gamma models are fit and cross-validated using an existing dataset of 6291 simulated registration examples, plus 699 novel simulated registrations withheld for independent validation. Average uncertainty and average proportion of TRE remaining after elastic registration are strongly correlated (r = 0.78), with mean absolute difference in predicted TRE equivalent to 0.9 ± 0.6 mm (cross-validation) and 0.9 ± 0.5 mm (independent validation). Spatial uncertainty maps also permit localized TRE estimates accurate to an equivalent of 3.0 ± 3.1 mm (cross-validation) and 1.6 ± 1.2 mm (independent validation). Additional clinical evaluation of vascular features yields localized TRE estimates accurate to 3.4 ± 3.2 mm. This work formalizes a lower bound for the inherent uncertainty of nonrigid elastic registrations given coverage of intraoperative data constraints, and demonstrates a relation to TRE that can be predictively leveraged to inform data collection and provide a measure of registration confidence for elastic methods.
journal_name
IEEE Trans Med Imagingjournal_title
IEEE transactions on medical imagingauthors
Heiselman JS,Miga MIdoi
10.1109/TMI.2021.3052523subject
Has Abstractpub_date
2021-01-18 00:00:00eissn
0278-0062issn
1558-254Xjournal_volume
PPpub_type
杂志文章abstract：:In magnetic resonance imaging (MRI), it is well-known that patient motion plays a significant role in the degradation of image quality. Although the case of translational in-plane motion (x-y-motion) has been studied by several researchers, the effect of rigid, translational out-of-plane motion (z-motion) has not yet ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.414611
更新日期：1995-01-01 00:00:00
abstract：:To reconstruct electrical activity in the heart from body-surface electrocardiograms (ECGs) is an ill-posed inverse problem. Electrophysiological models have been found effective in regularizing these inverse problems by incorporating a priori knowledge about how the electrical potential in the heart propagates over t...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2019.2906600
更新日期：2019-11-01 00:00:00
abstract：:The classification of 3 common breast lesions, fibroadenomas, cysts, and cancers, was achieved using computerized image analysis of tumor shape in conjunction with patient age. The process involved the digitization of 69 mammographic images using a video camera and a commercial frame grabber on a PC-based computer sys...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.251116
更新日期：1993-01-01 00:00:00
abstract：:The magnetic particle imaging (MPI) method directly images the magnetization of super-paramagnetic iron oxide (SPIO) nanoparticles, which are contrast agents commonly used in magnetic resonance imaging (MRI). MPI, as originally envisioned, requires a high-bandwidth receiver coil and preamplifier, which are difficult t...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2009.2013849
更新日期：2009-08-01 00:00:00
abstract：:A major issue in telepathology is the extremely large and growing size of digitized "virtual" slides, which can require several gigabytes of storage and cause significant delays in data transmission for remote image interpretation and interactive visualization by pathologists. Compression can reduce this massive amoun...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2010.2077308
更新日期：2011-02-01 00:00:00
abstract：:X-ray computed tomography (CT) using sparse projection views is a recent approach to reduce the radiation dose. However, due to the insufficient projection views, an analytic reconstruction approach using the filtered back projection (FBP) produces severe streaking artifacts. Recently, deep learning approaches using l...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2018.2823768
更新日期：2018-06-01 00:00:00
abstract：:The three-dimensional cardiac electrical imaging (3DCEI) technique was previously developed to estimate the initiation site(s) of cardiac activation and activation sequence from the noninvasively measured body surface potential maps (BSPMs). The aim of this study was to develop and evaluate the capability of 3DCEI in ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2012.2202914
更新日期：2012-09-01 00:00:00
abstract：:Coronary heart disease is a common cause of death despite being preventable. To treat the underlying plaque deposits in the arterial walls, intravascular optical coherence tomography can be used by experts to detect and characterize the lesions. In clinical routine, hundreds of images are acquired for each patient, wh...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2018.2865659
更新日期：2019-02-01 00:00:00
abstract：:This paper presents a fully automated algorithm for segmentation of multiple sclerosis (MS) lesions from multispectral magnetic resonance (MR) images. The method performs intensity-based tissue classification using a stochastic model for normal brain images and simultaneously detects MS lesions as outliers that are no...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.938237
更新日期：2001-08-01 00:00:00
abstract：:The performance of a classifier is largely dependent on the size and representativeness of data used for its training. In circumstances where accumulation and/or labeling of training samples is difficult or expensive, such as medical applications, data augmentation can potentially be used to alleviate the limitations ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2016.2640180
更新日期：2017-04-01 00:00:00
abstract：:Ultrasonic imaging is the noninvasive clinical imaging modality of choice for diagnosing heart disease. At present, two-dimensional ultrasonic grayscale images provide a relatively cheap, fast, bedside method to study the morphology of the heart. Several methods have been proposed to assess myocardial function. These ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2002.804440
更新日期：2002-09-01 00:00:00
abstract：:This paper describes several methods for magnetic resonance angiography that create projection images based solely on flowing blood. To both remove static tissue from the image and generate signals from blood, two classes of methods considered are temporal subtraction and cancelling excitation. Temporal subtraction, a...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.1986.4307763
更新日期：1986-01-01 00:00:00
abstract：:In picture archiving and communications systems (PACS), images need to be displayed in standardized ways for radiologists' interpretations. However, for most radiographs acquired via computed radiography (CR), digital radiography (DR), or digitized films, the image orientation is undetermined because of the variations...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/tmi.2006.880677
更新日期：2006-10-01 00:00:00
abstract：:Several techniques based on the three-dimensional (3-D) discrete cosine transform (DCT) have been proposed for volumetric data coding. These techniques fail to provide lossless coding coupled with quality and resolution scalability, which is a significant drawback for medical applications. This paper gives an overview...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/tmi.2003.809582
更新日期：2003-03-01 00:00:00
abstract：:Biomedical applications such as cell tracking and angiography require the detection of low concentrations of superparamagnetic iron oxide nanoparticles (SPIOs) for imaging purposes. Magnetic particle imaging (MPI) is a new technology which enables the quantitative and time-resolved localization of SPIO distributions. ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2015.2501462
更新日期：2016-03-01 00:00:00
abstract：:Magnetic resonance imaging (MRI) on patients with implanted deep brain stimulators (DBSs) can be hazardous because of the antenna-effect of leads exposed to the incident radio-frequency field. This study evaluated electromagnetic field and specific absorption rate (SAR) changes as a function of lead resistivity on an ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2010.2040624
更新日期：2010-04-01 00:00:00
abstract：:Many segmentation methods for thoracic volume data require manual input in the form of a seed point, initial contour, volume of interest etc. The aim of the work presented here is to further automate this segmentation initialization step. In this paper an anatomical modeling and matching method is proposed to coarsely...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.764893
更新日期：1999-03-01 00:00:00
abstract：:Sulcal fundi are 3-D curves that lie in the depths of the cerebral cortex and, in addition to their intrinsic value in brain research, are often used as landmarks for downstream computations in brain imaging. In this paper, we present a geometric algorithm that automatically extracts the sulcal fundi from magnetic res...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2006.886810
更新日期：2007-04-01 00:00:00
abstract：:This paper introduces and evaluates a block-iterative Fisher scoring (BFS) algorithm. The algorithm provides regularized estimation in tomographic models of projection data with Poisson variability. Regularization is achieved by penalized likelihood with a general quadratic penalty. Local convergence of the block-iter...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2008.918355
更新日期：2008-08-01 00:00:00
abstract：:In this paper, the accuracy of material decomposition (MD) using an energy discriminating photon counting detector was studied. An MD framework was established and validated using calcium hydroxyapatite (CaHA) inserts of known densities (50 mg/cm3, 100 mg/cm3, 250 mg/cm3, 400 mg/cm3), and diameters (1.2, 3.0, and 5.0 ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2019.2914370
更新日期：2020-01-01 00:00:00
abstract：:It is well known that the energy dependence of X-ray attenuation can be used to characterize materials. Yet, even with energy discriminating photon counting X-ray detectors, it is still unclear how to best form energy dependent measurements for spectral imaging. Common ideas include binning photon counts based on thei...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2010.2061862
更新日期：2011-01-01 00:00:00
abstract：:Synthetic phased array (SPA) beamforming with Hadamard coding and aperture weighting is an optimal option for real-time volumetric imaging with a ring array, a particularly attractive geometry in intracardiac and intravascular applications. However, the imaging frame rate of this method is limited by the immense compu...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2013.2253117
更新日期：2013-07-01 00:00:00
abstract：:Magnetic resonance (MR) tagging has been shown to be a useful technique for noninvasively measuring the deformation of an in vivo heart. An important step in analyzing tagged images is the identification of tag lines in each image of a cine sequence. Most existing tag identification algorithms require user defined myo...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.768842
更新日期：1999-04-01 00:00:00
abstract：:Accurate localization of anatomical landmarks is an important step in medical imaging, as it provides useful prior information for subsequent image analysis and acquisition methods. It is particularly useful for initialization of automatic image analysis tools (e.g. segmentation and registration) and detection of scan...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2016.2597270
更新日期：2017-01-01 00:00:00
abstract：:Fetal brain magnetic resonance imaging (MRI) offers exquisite images of the developing brain but is not suitable for second-trimester anomaly screening, for which ultrasound (US) is employed. Although expert sonographers are adept at reading US images, MR images which closely resemble anatomical images are much easier...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2020.3018560
更新日期：2020-12-01 00:00:00
abstract：:A true three-dimensional cone-beam reconstruction (TTCR) algorithm for direct volume image reconstruction from 2-D cone-beam projections is developed for the complete sphere geometry. The algorithm is derived from the parallel-beam true three-dimensional reconstruction (TTR) algorithm and is based on the modified filt...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.41483
更新日期：1989-01-01 00:00:00
abstract：:In this paper we propose a framework for using duplex Doppler ultrasound systems. These type of systems need to interleave the acquisition and display of a B-mode image and of the pulsed Doppler spectrogram. In a recent study (Richy , 2013), we have shown that compressed sensing-based reconstruction of Doppler signal ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2015.2504240
更新日期：2016-04-01 00:00:00
abstract：:An algorithm is presented for the analysis and quantification of the vascular structures of the human retina. Information about retinal blood vessel morphology is used in grading the severity and progression of a number of diseases. These disease processes are typically followed over relatively long time courses, and ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.363106
更新日期：1994-01-01 00:00:00
abstract：:We propose a novel, physics-based method for detecting multi-scale tubular features in ultrasound images. The detector is based on a Hessian-matrix eigenvalue method, but unlike previous work, our detector is guided by an optimal model of vessel-like structures with respect to the ultrasound-image formation process. O...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2014.2340912
更新日期：2015-01-01 00:00:00
abstract：:Epilepsy is a neurological disorder characterized by sudden and unpredictable epileptic seizures, which incurs significant negative impacts on patients' physical, psychological and social health. A practical approach to assist with the clinical assessment and treatment planning for patients is to process magnetoenceph...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2019.2958699
更新日期：2020-06-01 00:00:00
