Diabeloop DBLG1 Closed-Loop System Enables Patients With Type 1 Diabetes to Significantly Improve Their Glycemic Control in Real-Life Situations Without Serious Adverse Events: 6-Month Follow-up.

abstract：OBJECTIVE:The ability of the Adult Treatment Panel III (ATP III) criteria of metabolic syndrome to identify insulin-resistant subjects at increased cardiovascular risk is suboptimal, especially in the absence of obesity and diabetes. Nonalcoholic fatty liver disease (NAFLD) is associated with insulin resistance and is ...

journal_title：Diabetes care

authors： Musso G,Gambino R,Bo S,Uberti B,Biroli G,Pagano G,Cassader M

更新日期：2008-03-01 00:00:00

abstract：:OBJECTIVE Pharmacological profiles of biphasic insulin aspart 30/70 (BIAsp 30) once daily (OD), twice daily (b.i.d.), and three times daily (t.i.d.) were compared with other insulin regimens in two crossover glucose clamp studies of insulin-treated type 2 diabetic patients. RESEARCH DESIGNS AND METHODS Study 1 consist...

journal_title：Diabetes care

authors： Heise T,Heinemann L,Hövelmann U,Brauns B,Nosek L,Haahr HL,Olsen KJ

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:In 2010, the American Diabetes Association (ADA) added hemoglobin A1c (A1C) to the guidelines for diagnosing type 2 diabetes. However, existing models for predicting diabetes risk were developed prior to the widespread adoption of A1C. Thus, it remains unknown how well existing diabetes risk prediction models...

journal_title：Diabetes care

authors： Lacy ME,Wellenius GA,Carnethon MR,Loucks EB,Carson AP,Luo X,Kiefe CI,Gjelsvik A,Gunderson EP,Eaton CB,Wu WC

更新日期：2016-02-01 00:00:00

abstract：:Use of pure porcine insulin versus partially purified insulin of bovine/porcine origin might be expected to have certain clinical benefits, e.g., a lower incidence of skin reactions, a lower insulin dosage, better diabetes regulation, and greater preservation of endogenous insulin secretion. To test this hypothesis, w...

journal_title：Diabetes care

authors： Asplin C,Raghu P,Clemons P,Lyen K,Tatpati O,McKnight B,Baker L,Guthrie R,Sperling M,Palmer J

更新日期：1987-05-01 00:00:00

abstract：OBJECTIVE:To provide information about possible subclinical damage of the cochlear outer hair cells (OHCs) by means of transiently evoked otoacoustic emissions (TEOAEs) and distortion-product otoacoustic emissions (DPOAEs) in subjects with IDDM. RESEARCH DESIGN AND METHODS:TEOAEs and DPOAEs were recorded in 47 IDDM pa...

journal_title：Diabetes care

authors： Di Nardo W,Ghirlanda G,Paludetti G,Cercone S,Saponara C,Del Ninno M,Di Girolamo S,Magnani P,Di Leo MA

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:To compare the cost and time to diagnosis associated with several screening strategies for diabetes in women with histories of gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS:We simulated screening for diabetes with fasting plasma glucose (FPG), a 2-h oral glucose tolerance test (OGTT), and ...

journal_title：Diabetes care

authors： Kim C,Herman WH,Vijan S

更新日期：2007-05-01 00:00:00

abstract：:Serum free insulin concentrations were measured in diabetic subjects given insulin intravenously by a glucose-controlled insulin infusion system ("closed-loop" artificial beta-cell) in two experimental situations: hourly during the day while given their usual diet and at short intervals after administration of a stand...

journal_title：Diabetes care

authors： Horwitz DL,Zeidler A,Gonen B,Jaspan JB

更新日期：1980-03-01 00:00:00

abstract：OBJECTIVE:To determine the best autoantibody-based testing strategy for recruiting relatives for future intervention trials and to establish the role of islet cell antibodies (ICAs) within this strategy. RESEARCH DESIGN AND METHODS:ICAs, insulin autoantibodies (IAAs), GAD antibodies, and IA-2 antibodies were determine...

journal_title：Diabetes care

authors： Bingley PJ,Williams AJ,Gale EA

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVE:Little is known about medial arterial calcification (MAC) other than its association with age, sex, diabetes, and diabetes complications. Familial aggregation of this disorder was studied to determine the importance of potential genetic factors and to assess whether such familial aggregation was independent o...

journal_title：Diabetes care

authors： Narayan KM,Pettitt DJ,Hanson RL,Bennett PH,Fernandes RJ,De Courten M,Rose FA,Knowler WC

更新日期：1996-09-01 00:00:00

abstract：OBJECTIVE:High plasma adiponectin is associated with reduced risk of type 2 diabetes, probably a consequence of its insulin-sensitizing properties. In vivo data in rodents suggest that the insulin-sensitization responsible for improvement of glycemia occurs in muscle and liver. Whereas associations of plasma adiponecti...

journal_title：Diabetes care

authors： Stefan N,Stumvoll M,Vozarova B,Weyer C,Funahashi T,Matsuzawa Y,Bogardus C,Tataranni PA

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVE:There is enough evidence that physical activity is an effective therapeutic tool in the management of type 2 diabetes. The present study was designed to validate a counseling strategy that could be used by physicians in their daily outpatient practice to promote the adoption and maintenance of physical activi...

journal_title：Diabetes care

authors： Di Loreto C,Fanelli C,Lucidi P,Murdolo G,De Cicco A,Parlanti N,Santeusanio F,Brunetti P,De Feo P

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVE:To investigate whether peripheral neuropathy (PN), as part of the microangiopathic complex, affects bone mineral density (BMD) of the peripheral or the axial skeleton in patients with type 1 diabetes. RESEARCH DESIGN AND METHODS:Three study groups were examined. Group 1 comprised 21 males with type 1 diabete...

journal_title：Diabetes care

authors： Rix M,Andreassen H,Eskildsen P

更新日期：1999-05-01 00:00:00

abstract：OBJECTIVE:Subjects with type 1 diabetes are at high risk for many long-term complications, including early mortality and coronary artery disease (CAD). Few data are available on which to base goal levels for two major risk factors, namely blood pressure and lipid/lipoproteins. The objective of this study was to determi...

journal_title：Diabetes care

authors： Orchard TJ,Forrest KY,Kuller LH,Becker DJ,Pittsburgh Epidemiology of Diabetes Complications Study.

更新日期：2001-06-01 00:00:00

abstract：:OBJECTIVE Previous studies have demonstrated aberrant glucagon physiology in the setting of type 1 diabetes (T1D) but have not addressed the potential impact of ambient glycemia on this glucagon response. Thus, our objective was to evaluate the impact of euglycemia versus hyperglycemia on the glucagon response to an o...

journal_title：Diabetes care

authors： Kramer CK,Borgoño CA,Van Nostrand P,Retnakaran R,Zinman B

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy of a lifestyle intervention program that can be readily translated into clinical practice for obese patients with type 2 diabetes. RESEARCH DESIGN AND METHODS:The study consisted of a 12-month randomized controlled trial of 147 health plan members with type 2 diabetes and obesity (BMI ...

journal_title：Diabetes care

authors： Wolf AM,Conaway MR,Crowther JQ,Hazen KY,L Nadler J,Oneida B,Bovbjerg VE,Improving Control with Activity and Nutrition (ICAN) Study.

更新日期：2004-07-01 00:00:00

abstract：:Cyclosporin and other immunosuppressive agents have been proposed as a preventive treatment against the development of insulin-dependent diabetes mellitus (IDDM) in relatives at increased risk for the disease, based on the understanding that its etiology is an ongoing process of autoimmune beta-cell destruction. We us...

journal_title：Diabetes care

authors： Lipton R,LaPorte RE,Becker DJ,Dorman JS,Orchard TJ,Atchison J,Drash AL

更新日期：1990-07-01 00:00:00

abstract：OBJECTIVE:Consumption of soy protein has recently been shown to improve the blood lipid levels in nondiabetic subjects. The purpose of this study was to evaluate if a dietary supplement of soy protein, isoflavones, and cotyledon fiber (Abalon) affects cardiovascular risk markers, blood glucose, and insulin levels in ty...

journal_title：Diabetes care

authors： Hermansen K,Søndergaard M,Høie L,Carstensen M,Brock B

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVE:To study the influence of position changes on 24-h ambulatory blood pressure (ABP) in normotensive or mildly hypertensive normoalbuminuric patients with type 1 diabetes. RESEARCH DESIGN AND METHODS:A cross-sectional evaluation of patients was staged according to the duration of diabetes (DD) and the presence...

journal_title：Diabetes care

authors： Benhamou PY,Mouret S,Quesada JL,Boizel R,Baguet JP,Halimi S,Mallion JM

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVE:This study was designed to examine metabolic and hormonal effects of long-term exercise in healthy subjects and insulin-dependent (type I) diabetic patients. RESEARCH DESIGN AND METHODS:Two studies were performed. First, 16 healthy males (32 +/- 3 yr) were studied during a semitriathlon competition (2 km swi...

journal_title：Diabetes care

authors： Koivisto VA,Sane T,Fyhrquist F,Pelkonen R

更新日期：1992-11-01 00:00:00

abstract：:Twenty-eight patients with type I diabetes mellitus, legally blind as a result of proliferative retinopathy, were recruited into a program designed to teach and evaluate tactile methods for self-monitoring of blood glucose (SMBG). Vision ranged from "blind" to "able to read large print." Techniques with wipe-off strip...

journal_title：Diabetes care

authors： Prior JC,Alojado NC,Hunt JA,Begg IS

更新日期：1984-07-01 00:00:00

abstract：:Of the 30,300 mothers who attended consecutively at the antenatal clinic during an 11-yr period, 3063 mothers screened positive using clinical criteria for potential diabetes in pregnancy. These 3063 mothers had a glucose tolerance test (GTT), of which 661 were judged abnormal. At different times an oral GTT, cortison...

journal_title：Diabetes care

authors： Hadden DR

更新日期：1980-05-01 00:00:00

abstract：OBJECTIVE:Blood pressure ranges associated with cardiovascular disease (CVD) events in advanced type 2 diabetes are not clear. Our objective was to determine whether baseline and follow-up (On-Study) systolic blood pressure (SBP), diastolic blood pressure (DBP), and SBP combined with DBP predict CVD events in the Veter...

journal_title：Diabetes care

authors： Anderson RJ,Bahn GD,Moritz TE,Kaufman D,Abraira C,Duckworth W,VADT Study Group.

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To determine, after 1 yr of follow-up in type II diabetes patients, whether a statistically and clinically significant difference can be achieved in HbA1c between a standard therapy group and an intensively treated group, while maintaining HbA1c levels in both groups within ranges acceptable in regular commun...

journal_title：Diabetes care

authors： Abraira C,Emanuele N,Colwell J,Henderson W,Comstock J,Levin S,Nuttall F,Sawin C

更新日期：1992-11-01 00:00:00

abstract：OBJECTIVE:Type 1 diabetes mellitus causes increased carotid intima-media thickness (IMT) in adults. We evaluated IMT in young subjects with type 1 diabetes. RESEARCH DESIGN AND METHODS:Participants with type 1 diabetes (N = 402) were matched to controls (N = 206) by age, sex, and race or ethnicity. Anthropometric and ...

journal_title：Diabetes care

authors： Urbina EM,Dabelea D,D'Agostino RB Jr,Shah AS,Dolan LM,Hamman RF,Daniels SR,Marcovina S,Wadwa RP

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:To determine the effect of treatment with insulin aspart compared with NPH insulin, together with metformin/placebo and rosiglitazone/placebo. The hypothesis was that combined correction of major pathogenetic defects in type 2 diabetes would result in optimal glycemic control. RESEARCH DESIGN AND METHODS:Thi...

journal_title：Diabetes care

authors： Gram J,Henriksen JE,Grodum E,Juhl H,Hansen TB,Christiansen C,Yderstræde K,Gjessing H,Hansen HM,Vestergaard V,Hangaard J,Beck-Nielsen H

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:Major depressive disorder (MDD) and type 2 diabetes have independent adverse effects on sexual functioning (SF). Bupropion (BU) reportedly has few sexual side effects, but its use in diabetes has not been studied. RESEARCH DESIGN AND METHODS:This article reports a planned secondary analysis of SF in 90 patie...

journal_title：Diabetes care

authors： Sayuk GS,Gott BM,Nix BD,Lustman PJ

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:Assessing updated incidence of type 1 diabetes in 0- to 14-year-old children in Liguria, a Northwest region of Italy. RESEARCH DESIGN AND METHODS:Incident cases were recorded prospectively from 1989 to 1998. Incidence rates (IRs) were standardized to the 1999 world population using the direct method. The ind...

journal_title：Diabetes care

authors： Cotellessa M,Barbieri P,Mazzella M,Bonassi S,Minicucci L,Lorini R

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVE:It has been suggested that individuals with the condition known as metabolically healthy obesity (MHO) may not have the same increased risk for the development of metabolic abnormalities as their non-metabolically healthy counterparts. However, the validity of this concept has recently been challenged, since ...

journal_title：Diabetes care

authors： Gómez-Ambrosi J,Catalán V,Rodríguez A,Andrada P,Ramírez B,Ibáñez P,Vila N,Romero S,Margall MA,Gil MJ,Moncada R,Valentí V,Silva C,Salvador J,Frühbeck G

更新日期：2014-10-01 00:00:00

abstract：:Natriuretic peptides (NPs) play a key role in cardiovascular homeostasis, counteracting the deleterious effects of volume and pressure overload and activating antibrotic and antihypertrophic pathways in the heart. N-terminal B-type NP (NT-proBNP) also is a promising biomarker of global cardiovascular risk in the gener...

journal_title：Diabetes care

authors： Gruden G,Landi A,Bruno G

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that microalbuminuria may show an independent statistical association with diabetic neuropathy. RESEARCH DESIGN AND METHODS:An observational study of a prospectively identified cohort was conducted at the University Medical Center. The cohort consisted of 78 consecutive diabetic patien...

journal_title：Diabetes care

authors： Bell DS,Ketchum CH,Robinson CA,Wagenknecht LE,Williams BT

更新日期：1992-04-01 00:00:00