Immunolocalization of androgen and vitamin D receptors in the epididymis of mature ram (Ovis aries).

Abstract:

:This study illustrated the immunohistochemical distribution of androgen and vitamin D receptors of epididymis in 20 sexually mature ram (Rahmani breed) with average age ranged from (2_4) years and average weight ranged from (50_65kg). Androgen receptor was localized in the cytoplasm of both ciliated and non ciliated cells of efferent ductules, besides the principal cells via the entire epididymal duct. The principal cells of both corpus and proximal cauda epididymis showed the highest immunoreactivity to androgen receptors. Furthermore, vitamin D receptor was localized in the cytoplasm of all epithelium of the efferent ductules besides principal cells of all epididymal regions, however the immunoreaction was significantly higher in the efferent ductules, distal caput and distal cauda epididymis. In conclusion, these results suggest that the function of ram epididymis is regulated by both androgen and Vitamin D.

journal_name

Saudi J Biol Sci

authors

Mansour YA,Mosallam EMM,Hussein S,Elleithy EMM,Moussa IM,Mubarak AS,Dawoud TM,Alsubki RA,Alhaji JH,Hemeg HA,El-Bargeesy GAH

doi

10.1016/j.sjbs.2020.09.051

subject

Has Abstract

pub_date

2021-01-01 00:00:00

pages

217-223

issue

1

eissn

1319-562X

issn

2213-7106

pii

S1319-562X(20)30457-5

journal_volume

28

pub_type

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