Abstract：
:The traditional approach to gastric outlet obstruction caused by unresectable pancreatic cancer is gastrojejunostomy performed during or after biliary bypass surgery. Previous work showed that gastrojejunostomy failed in 95% of patients with preoperative outlet obstruction, which was evidenced by nausea and vomiting. This study defines a better bypass procedure, namely, antrectomy with gastrojejunostomy, which was performed in 19 such patients. The cancer was primary pancreatic in 17 patients and metastatic to the pancreas in two patients with a renal and urinary bladder primary. All patients had duodenal extension with impaired alimentation. Fourteen patients underwent simultaneous biliary bypass surgery and antrectomy with gastrojejunostomy; the antrectomy with gastrojejunostomy procedure was performed in five patients 3 weeks to 6 months after biliary bypass surgery when duodenal obstruction supervened. Visible cancer extended to the duodenal stump in five patients, including two patients whose partial closure was buttressed with omentum. All 19 patients tolerated regular diet at the time of discharge 1 to 4 weeks after the antrectomy with gastrojejunostomy procedure. All patients, who died at 4 to 21 months after surgery tolerated solid food until immediately before death. All nine surviving patients have taken solid foods 9 to 29 months since the antrectomy with gastrojejunostomy procedure. We conclude that the antrectomy with gastrojejunostomy procedure, whether performed simultaneously with or subsequently to biliary bypass surgery, is the best palliative procedure for duodenal obstruction in patients with unresectable pancreatic cancer.
journal_name
Surgeryjournal_title
Surgeryauthors
Lucas CE,Ledgerwood AM,Bender JSsubject
Has Abstractpub_date
1991-10-01 00:00:00pages
583-9; discussion 589-90issue
4eissn
0039-6060issn
1532-7361journal_volume
110pub_type
杂志文章相关文献
SURGERY文献大全abstract：BACKGROUND:Because the adhesive glycoprotein von Willebrand Factor (vWF) mediates initial platelet attachment at sites of vascular injury and may also contribute to shear-dependent platelet thrombus formation, we have determined in vivo the relative antithrombotic efficacy and hemostatic safety of infusing murine monoc...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1992-08-01 00:00:00
abstract：BACKGROUND:Only annual mammography and physical examination are recommended for the post-treatment surveillance of early stage breast cancer. METHODS:We used Texas Cancer Registry-Medicare linked data (2001-2007) to identify physician visits and use of mammography, magnetic resonance imaging (MRI), computed tomography...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2013.04.004
更新日期：2013-08-01 00:00:00
abstract：BACKGROUND:Regulation of coronary vasomotor tone by serotonin is significantly changed after cardioplegic arrest and reperfusion. The current study investigates whether cardiopulmonary bypass may also affect peripheral arteriolar response to serotonin in patients with or without diabetes. METHODS:Human peripheral micr...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2018.03.007
更新日期：2018-08-01 00:00:00
abstract：:A preliminary subcutaneous dose of heparin given with premedication, followed by a continuous infusion of low-dose heparin up to 2 hours after operation, was given to 20 of 40 patients undergoing major abdominal operation randomly allocated to either act as controls or receive prophylaxis. The anticoagulant effect of ...
journal_title：Surgery
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1984-09-01 00:00:00
abstract：BACKGROUND:High rates of extrapancreatic malignancies (EPM) have been observed in patients with intraductal papillary mucinous neoplasm (IPMN). IPMN in patients with familial pancreatic cancer have also been reported. Our purpose was to evaluate the association of IPMN with EPM, malignancies in family members, and germ...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2011.06.036
更新日期：2012-01-01 00:00:00
abstract：BACKGROUND:The prognosis of neuroblastoma patients remains unsatisfactory. Therefore, developing an effective treatment strategy is important. Resveratrol, a natural polyphenol, possesses chemopreventive and antitumor effects. We investigated the effects of resveratrol on the proliferation, apoptosis, and cell cycle al...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2004.01.017
更新日期：2004-07-01 00:00:00
abstract：:Severe abdominal pain was the major indication for operation in 85 patients with chronic pancreatitis. Preoperative endoscopic retrograde cholangiopancreatography (50 patients) or intraoperative pancreatic ductograms (44 patients) demonstrated dilated or obstructed major pancreatic ducts in 50 patients (59%), nonvisua...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1984-10-01 00:00:00
abstract：BACKGROUND:In the evaluation of patients with primary hyperparathyroidism (PHP), specific query for a personal or family history of MEN1 (Hx) is recommended widely, but responses are rarely positiv. We instituted a 6-question panel (6Q) to routinely screen for MEN1 preoperatively. METHODS:The clinical database entries...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2008.07.030
更新日期：2008-12-01 00:00:00
abstract：BACKGROUND:Interleukin (IL)-10 is a potent antiinflammatory cytokine inhibiting the release of tumor necrosis factor--alpha (TNF-alpha) and IL-8 by activated macrophages and polymorphonuclear leukocytes. Cardiopulmonary bypass (CPB) represents a unique situation where an inflammatory reaction is predictably induced. Th...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/s0039-6060(96)80217-0
更新日期：1996-01-01 00:00:00
abstract：:From 1951 through 1975, 72 patients with congenital intrinsic duodenal obstruction were seen at the Childrens Hospital of Los Angeles. The survival rate was 55% during the first 15 years of the study, but this has increased to 88% during the last 10 years. Factors important to this increased survival rate include: ear...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1977-11-01 00:00:00
abstract：BACKGROUND:Laparoscopy has become an increasingly important diagnostic tool for the staging of intraabdominal malignancies. Some investigators have suggested laparoscopy to be of questionable value in the preoperative staging of gastric cancer because many patients may require palliative surgery despite laparoscopic fi...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/s0039-6060(96)80184-x
更新日期：1996-06-01 00:00:00
abstract：BACKGROUND:The importance of cigarette smoking in the etiology of peripheral arterial occlusive disease is well known, but there have been few studies that have quantified this relationship. METHODS:A case-control study design was used in which the case subjects were men with a history of claudication for at least 1 y...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1993-10-01 00:00:00
abstract：BACKGROUND:Early survival after pancreaticoduodenectomy has improved, but its morbidity remains high. The purpose of this study is to determine how the intra-operative (OR) occurrence of major vascular complications affects the outcome of pancreaticoduodenectomy. METHODS:The medical records of 180 consecutive patients...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1067/msy.2002.127688
更新日期：2002-10-01 00:00:00
abstract：:The release of oxygen radicals, in particular the hydroxyl radical, from sequestered neutrophils produces acute lung injury after a number of insults. Our purpose was to determine whether hydroxyl radical, OH., is responsible for the lung injury from endotoxin characterized by (1) pulmonary leukostasis, (2) increased ...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1985-03-01 00:00:00
abstract：:A long-acting somatostatin analog, SMS 201-995, is now available to treat the hormonal manifestations of islet cell tumors. We report its use in a patient with a metastatic glucagonoma refractory to conventional therapy. This patient, who was severely disabled by the rash of necrolytic migratory erythema and brittle d...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1986-12-01 00:00:00
abstract：BACKGROUND:Obesity is known as a risk factor for intra- and postoperative complications in pancreatic operation. However, the operative outcomes in obese patients undergoing laparoscopic distal pancreatectomy remain unclear. METHODS:A total number of 423 patients underwent laparoscopic distal pancreatectomy at Oslo Un...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2016.05.046
更新日期：2016-11-01 00:00:00
abstract：:We studied the effect of partial excision and wound closure on the postburn hypermetabolic state. A 25% of total body surface burn was produced in seven sheep. Oxygen consumption (VO2) was significantly increased to 215 +/- 44 ml/min/M2 by day 3 compared with baseline of 125 +/- 21 ml/min/M2. The calculated increase w...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1988-11-01 00:00:00
abstract：BACKGROUND:Lung injury is a life-threatening complication in patients with liver dysfunction. We recently provided an experimental lung injury model in mouse with common bile duct ligation. In this study, we aimed to characterize the pathologic and biochemical features of lung tissues in common bile duct ligation mice ...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2016.12.017
更新日期：2017-06-01 00:00:00
abstract：BACKGROUND:Although there exists robust literature on mortality-associated factors in burn patients, it is not known how electronic medical records affect outcomes. Using burn injury as a surgical care model of information and communication, we hypothesized that functionality and interoperability of the electronic medi...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2018.07.010
更新日期：2018-10-01 00:00:00
abstract：BACKGROUND:Necrotizing enterocolitis is the leading case of gastrointestinal-related morbidity in premature infants. Necrotizing enterocolitis totalis is an aggressive form of necrotizing enterocolitis, which has traditionally been managed with comfort care. Recent advances in management of short bowel syndrome have re...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2019.03.005
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:Four-dimensional computed tomography (4D-CT) provides both functional and highly detailed anatomic information about parathyroid tumors. The purpose of this study was to compare 4D-CT with sestamibi imaging and ultrasonography as methods for the accurate preoperative localization of hyperfunctioning parathyr...
journal_title：Surgery
pub_type： 临床试验,杂志文章
doi：10.1016/j.surg.2006.07.028
更新日期：2006-12-01 00:00:00
abstract：:To prevent aneurysm rupture, avoid pseudoaneurysm formation, and preserve intercostal arteries, a new procedure for repair of DeBakey type 3 dissecting aneurysm was developed. Since January 1977, 28 patients have undergone repair of type 3 dissecting aneurysm. Fifteen patients with type 3b underwent this new procedure...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:A case of abdominal aortic aneurysm associated with renovascular hypertension in a 3-year-old boy is reported. The child was treated by resection of the aneurysm and replacement with a 12 mm polyester (Dacron) bifurcated graft. The cause of the aneurysm was not revealed by clinical and pathologic examination. In addit...
journal_title：Surgery
pub_type： 杂志文章,评审
doi：
更新日期：1989-09-01 00:00:00
abstract：:Eighteen patients with arteriovenous malformations (AVM's) involving the extremities, pelvis, or head are reported and their treatment is discussed. Our experience has led us to the following conclusions: (1) careful selective angiography is mandatory to delineate the vascular anatomy, extent, and major afferent vesse...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1976-01-01 00:00:00
abstract：:A prospective, randomized, double-blind, endoscopic study is described in which the efficacy of cimetidine (13 patients) is compared to that of antacids (14 patients) in the prevention of stress ulceration following severe thermal injury. Each treatment modality was equally effective in the prevention of acute gastrod...
journal_title：Surgery
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1979-10-01 00:00:00
abstract：BACKGROUND:No reports have yet precisely determined corticotropin (ACTH) responsiveness in virilizing adrenocortical adenoma. METHODS:Five women with an androgen-secreting adrenal adenoma were reviewed. Three of them were examined by in vitro steroidogenesis. Two of these 3 patients were studied by immunohistochemistr...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1999-04-01 00:00:00
abstract：:Social media is a necessary component of the practice of surgery. Each surgeon must embrace the power and potential of social media and serve as a guide or content expert for patients and other health care providers to facilitate and share responsible use of the various media available. Social media facilitates rapid ...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2015.06.002
更新日期：2015-09-01 00:00:00
abstract：BACKGROUND:The development of pancreatic cancer involves an accumulation of genetic changes, including oncogene activation and mutations in tumor suppressor genes important in cell cycle regulation. As a step to developing gene therapies to restore cell cycle control, we hypothesized that adenoviral-mediated gene trans...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/s0039-6060(97)90036-2
更新日期：1997-08-01 00:00:00
abstract：BACKGROUND:The incidence of reoperation for adhesive bowel obstruction after general abdominal surgery is 2.5% and carries a considerable risk of mortality and morbidity. Adhesions account for 56% of all cases of bowel obstruction. Most epidemiologic knowledge regarding adhesive bowel obstruction is derived from data o...
journal_title：Surgery
pub_type： 临床试验,杂志文章
doi：10.1016/j.surg.2015.11.016
更新日期：2016-05-01 00:00:00
abstract：:Forty-seven patients with 50 clinically occult injuries of major arteries were studied prospectively to determine the natural history of these lesions and the safety of nonoperative management. Penetrating trauma was the predominant mechanism and lower extremity arteries were most commonly involved. The morphology of ...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
