Abstract:
:Since perioperative anaphylaxis occurs suddenly, and it can be life-threatening, anesthesiologists need to have sufficient knowledge of the epidemiology of perioperative anaphylaxis and appropriate coping strategies to deal with it. Recent studies conducted in Western countries reported the characteristics of perioperative anaphylaxis in each country. However, there are few studies of perioperative anaphylaxis in Japan. To bridge the gap between Japan and other countries, the data of 46 anaphylaxis patients at Gunma University Hospital and 13 neighboring hospitals between 2012 and 2018 were collected and analyzed. The recently developed clinical scoring system was combined with a skin test to include only cases with a definite diagnosis. The most common causative agents were sugammadex, followed by rocuronium, cefazolin, and antibiotics other than cefazolin. Furthermore, the characteristics of anaphylaxis for each causative drug were identified. Time from drug administration to appearance of the first symptom was the longest in the cefazolin group. The incidence of canceled operation was the highest in the rocuronium group. Although it is unclear whether the results of this study can apply to Japan as a whole, the information about the agents responsible for perioperative anaphylaxis and the characteristics of anaphylaxis due to each agent would be helpful to anesthesiologists.
journal_name
J Anesthjournal_title
Journal of anesthesiaauthors
Horiuchi T,Takazawa T,Orihara M,Sakamoto S,Nagumo K,Saito Sdoi
10.1007/s00540-020-02886-5subject
Has Abstractpub_date
2021-02-01 00:00:00pages
154-160issue
1eissn
0913-8668issn
1438-8359pii
10.1007/s00540-020-02886-5journal_volume
35pub_type
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journal_title:Journal of anesthesia
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更新日期:2011-12-01 00:00:00
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journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-003-0187-3
更新日期:2003-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s00540-010-0946-x
更新日期:2010-08-01 00:00:00
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journal_title:Journal of anesthesia
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doi:10.1007/s0054000040242
更新日期:1990-07-01 00:00:00
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更新日期:2010-06-01 00:00:00
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更新日期:2007-01-01 00:00:00
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journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02483394
更新日期:1996-12-01 00:00:00
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journal_title:Journal of anesthesia
pub_type: 杂志文章
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更新日期:2011-10-01 00:00:00
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更新日期:1994-06-01 00:00:00
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pub_type: 杂志文章
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journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
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更新日期:2006-01-01 00:00:00
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journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-007-0598-7
更新日期:2008-01-01 00:00:00
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journal_title:Journal of anesthesia
pub_type: 杂志文章,评审
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更新日期:2020-12-01 00:00:00
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journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-018-2551-3
更新日期:2018-10-01 00:00:00
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journal_title:Journal of anesthesia
pub_type: 杂志文章
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更新日期:2011-04-01 00:00:00
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journal_title:Journal of anesthesia
pub_type: 杂志文章
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更新日期:2017-02-01 00:00:00
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journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-016-2140-2
更新日期:2016-06-01 00:00:00
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journal_title:Journal of anesthesia
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00540-011-1261-x
更新日期:2012-02-01 00:00:00