Men and women affected by Sars-CoV-2 pneumonia: same CT features but different outcome.

Abstract:

AIM:To compare the computed tomography (CT) features of Sars-CoV-2 pneumonia between the two sexes and among different age groups. MATERIALS AND METHODS:Consecutive patients (n=331) who presented to the emergency department and underwent chest CT and reverse transcription polymerase chain reaction (RT-PCR) with a time interval <7 days, which were subsequently found to be consistent with Sars-CoV-2 infection, were enrolled retrospectively. Two experienced radiologists evaluated the images in consensus, recording the number of pulmonary lobes with ground-glass opacities and with consolidation. A CT score was subsequently calculated based on the percentage involvement of each lobe. Clinical symptoms, comorbidities, and level of required hospitalisation were noted. In-hospital mortality was recorded and analysed via the Kaplan-Meier estimator. RESULTS:Males and females had the same age distribution. No statistically significant difference was found in the analysed CT features and in the CT score (p=0.31) between the sexes. More females were affected by two or more comorbidities (17.1% versus 7.5%, p=0.024), all comorbidities except diabetes were more prevalent in females. Women had a higher probability to be discharged home and a lower probability to be admitted to the intensive care unit (ICU; p=0.008), in-hospital mortality was inferior (13.5% versus 22%). CONCLUSION:Despite more comorbidities, women had lower hospital admission and mortality, which was independent of CT findings between both sexes.

journal_name

Clin Radiol

journal_title

Clinical radiology

authors

Percivale I,Danna PSC,Falaschi Z,Berardo S,Gangi S,Tricca S,Castello LM,Barini M,Airoldi C,Carriero A

doi

10.1016/j.crad.2020.11.119

subject

Has Abstract

pub_date

2020-12-11 00:00:00

eissn

0009-9260

issn

1365-229X

pii

S0009-9260(20)30629-2

pub_type

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