Abstract：
:The novel corona virus termed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread throughout the globe at a formidable speed, causing tens of millions of cases and more than one million deaths in less than a year of its report in December 2019. Since then, companies and research institutions have raced to develop SARS-CoV-2 vaccines, ranging from conventional viral and protein-based vaccines to those that are more cutting edge, including DNA- and mRNA-based vaccines. Each vaccine exhibits a different potency and duration of efficacy, as determined by the antigen design, adjuvant molecules, vaccine delivery platforms, and immunization method. In this review, we will introduce a few of the leading non-viral vaccines that are under clinical stage development and discuss delivery strategies to improve vaccine efficacy, duration of protection, safety, and mass vaccination.
journal_name
Adv Drug Deliv Revjournal_title
Advanced drug delivery reviewsauthors
Park KS,Sun X,Aikins ME,Moon JJdoi
10.1016/j.addr.2020.12.008subject
Has Abstractpub_date
2021-02-01 00:00:00pages
137-151eissn
0169-409Xissn
1872-8294pii
S0169-409X(20)30279-9journal_volume
169pub_type
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journal_title：Advanced drug delivery reviews
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journal_title：Advanced drug delivery reviews
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journal_title：Advanced drug delivery reviews
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journal_title：Advanced drug delivery reviews
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journal_title：Advanced drug delivery reviews
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journal_title：Advanced drug delivery reviews
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journal_title：Advanced drug delivery reviews
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