One-year experience of nucleic acid technology testing for human immunodeficiency virus Type 1, hepatitis C virus, and hepatitis B virus in Thai blood donations.

Abstract:

BACKGROUND:Blood donations collected at the National Blood Center, the Thai Red Cross Society, Bangkok, in 2007 were tested by nucleic acid amplification technology (NAT) using the Chiron TIGRIS/Procleix Ultrio test and the Roche cobas s 201/cobas TaqScreen multiplex (MPX) test. STUDY DESIGN AND METHODS:The sensitivity, specificity, and robustness were determined by testing 486,676 seronegative blood donations. Samples from each day of collection were divided into two sets; the odd-numbered samples were tested individually on the TIGRIS and the even-numbered samples were tested in pools of 6 on the cobas s 201. The status of reactive samples was confirmed by duplicate testing of samples from the plasma bag to calculate the test specificity. Reactive samples were tested on the alternate system and followed up. RESULTS:The analytical sensitivity of both systems met the 95% limits of detection claimed by the respective package inserts. No cross contamination was seen with either system. Test specificity was 99.93 and 99.90% for the Procleix Ultrio and cobas TaqScreen tests, respectively. The NAT yield rates for human immunodeficiency virus Type 1 (HIV-1), hepatitis C virus (HCV), and hepatitis B virus (HBV) were 1:97,000, 1:490,000, and 1:2800, respectively. Several occult HBV donors, the majority of whom were detected by both tests, were also identified. The HIV-1 and HCV window cases were detected with both tests. CONCLUSION:The performances of the systems and tests indicated that both were acceptable for routine NAT by the National Blood Center, the Thai Red Cross Society. However, the Procleix Ultrio test appeared to be less sensitive than the cobas TaqScreen test for HBV.

journal_name

Transfusion

journal_title

Transfusion

authors

Phikulsod S,Oota S,Tirawatnapong T,Sakuldamrongpanich T,Chalermchan W,Louisirirotchanakul S,Tanprasert S,Chongkolwatana V,Kitpoka P,Phanuphak P,Wasi C,Nuchprayoon C,Working Group for NAT Study in Thai Blood Donations.

doi

10.1111/j.1537-2995.2009.02176.x

subject

Has Abstract

pub_date

2009-06-01 00:00:00

pages

1126-35

issue

6

eissn

0041-1132

issn

1537-2995

pii

TRF02176

journal_volume

49

pub_type

杂志文章
  • Potassium load in CPD-preserved whole blood and two types of packed red blood cells.

    abstract::The potassium load of transfused blood must be minimized. We have compared the total plasma potassium content of units of CPD-preserved stored whole blood (SWB), stored packed cells (SPC), and packed cells prepared from stored whole blood (WB-PC). Plasma potassium concentrations, unit weights, and hematocrits of 20 un...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1975.15275122809.x

    authors: Michael JM,Dorner I,Bruns D,Ladenson JH,Sherman LA

    更新日期:1975-03-01 00:00:00

  • Preparation of white cell-reduced platelet concentrates from whole blood during component preparation.

    abstract::This article introduces a new method of component preparation that is capable of producing white cell (WBC)-reduced platelet concentrates (PCs) from whole blood. Whole blood is separated into packed red cells (RBCs) and platelet-rich plasma (PRP) by centrifugation, and the PRP is expressed through a newly designed WBC...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1991.31691306254.x

    authors: Dzik WH,Cusack WF,Gacek MJ

    更新日期:1991-07-01 00:00:00

  • Development of a real-time polymerase chain reaction assay for sensitive detection and quantitation of Babesia microti infection.

    abstract:BACKGROUND:Babesia microti, the most frequently implicated pathogen in transfusion-transmitted babesiosis, is widely endemic in the Northeast and upper Midwestern United States. High seroprevalence in endemic areas limits antibody-based donor screening. A high-performance molecular test is needed to identify donors in ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.12098

    authors: Bloch EM,Lee TH,Krause PJ,Telford SR 3rd,Montalvo L,Chafets D,Usmani-Brown S,Lepore TJ,Busch MP

    更新日期:2013-10-01 00:00:00

  • Immune-mediated hemolysis associated with the administration of a radiographic contrast medium.

    abstract::A female patient developed serious hemolysis in association with the injection of a radiographic contrast medium (RCM). Serologic investigation of her serum suggested complement-mediated hemolysis, induced by an RCM-dependent IgM antibody in her serum. The antibody was of high titer and low avidity. The antibody showe...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1991.31992094673.x

    authors: Nordhagen R,Vik H,Wolthuis K,Bøhn HP,Urdahl P,Michaelsen TE

    更新日期:1991-11-01 00:00:00

  • Blood supply safety in Afghanistan: a national assessment of high-volume facilities.

    abstract:BACKGROUND:Little information is available regarding blood supply safety in Afghanistan. The purpose of this study was to assess blood safety through serologic and observational measures in Afghanistan. STUDY DESIGN AND METHODS:This cross-sectional assessment included the 40 highest-volume facilities collecting and tr...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.12005

    authors: Mansoor GF,Rahmani AM,Kakar MA,Hashimy P,Abrahimi P,Scott PT,Peel SA,Rentas FJ,Todd CS

    更新日期:2013-09-01 00:00:00

  • Current challenges for CAR T-cell therapy of acute myeloid leukemia.

    abstract::KEY IDEAS Chimeric antigen receptor (CAR) T-cell therapy has the potential to improve the dismal outcome of patients diagnosed with acute myeloid leukemia (AML). A major challenge for CAR T-cell therapy of AML patients is identifying leukemia-specific target antigens. Immune escape through down-regulation of target an...

    journal_title:Transfusion

    pub_type: 杂志文章,评审

    doi:10.1111/trf.15199

    authors: Sauer T,Rooney CM

    更新日期:2019-04-01 00:00:00

  • Self-reported historic human immunodeficiency virus (HIV) testing in a Brazilian blood donor HIV case-control study.

    abstract:BACKGROUND:There has been increased worldwide emphasis on the many benefits of human immunodeficiency virus (HIV) serostatus awareness for both infection prevention and improved treatment outcomes. Previous studies indicate that donors may use blood donation to be tested; the objectives of this analysis were to assess,...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.13792

    authors: Bruhn R,Moreno E,Sabino EC,Ferreira NA,Carneiro-Proietti AB,Lopes ME,Sampaio D,Loureiro P,Custer B,Goncalez TT,National Heart, Lung and Blood Institute Retrovirus Epidemiology Donor Study-II (REDS-II) International Component.

    更新日期:2016-11-01 00:00:00

  • The prevalence of human parvovirus B19 DNA and antibodies in blood donors from four Chinese blood centers.

    abstract:BACKGROUND:Human parvovirus B19 is a common human pathogen that causes a variety of diseases with outcomes ranging from asymptomatic to severe, especially in immunocompromised patients. The B19 virus can be transmitted via blood and/or blood products and its resistance to common viral inactivation and/or removal method...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2011.03067.x

    authors: Ke L,He M,Li C,Liu Y,Gao L,Yao F,Li J,Bi X,Lv Y,Wang J,Hirsch ML,Li W

    更新日期:2011-09-01 00:00:00

  • Clinical outcomes and transfusion management following intracranial hemorrhage in patients with acute leukemia.

    abstract:BACKGROUND:There is little evidence to guide management of patients with acute leukemia and intracranial hemorrhage (ICH). Predictors of long-term outcome following ICH are unknown. STUDY DESIGN AND METHODS:This study included adult patients with acute leukemia and ICH over an 8-year period. The primary outcome was da...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15621

    authors: Nixon S,Lieberman L,Atenafu EG,Doherty M,Murray C,Wolfe A,Brandys D,Rowland S,Kwan BY,Yu E,Lechner B,Maze D

    更新日期:2020-02-01 00:00:00

  • Hepatitis B virus nucleic acid amplification testing of Australian blood donors highlights the complexity of confirming occult hepatitis B virus infection.

    abstract:BACKGROUND:We present an analysis of the first 2 years of hepatitis B virus (HBV) nucleic acid testing (NAT) of the Australian donor population. STUDY DESIGN AND METHODS:Between July 5, 2010, and July 4, 2012, all blood donations were screened for HBV DNA and hepatitis B surface antigen (HBsAg). Donors who tested HBsA...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.12556

    authors: Kiely P,Margaritis AR,Seed CR,Yang H,Australian Red Cross Blood Service NAT Study Group.

    更新日期:2014-08-01 00:00:00

  • WBC alloimmunization: effects on the laboratory and clinical endpoints of therapeutic granulocyte transfusions.

    abstract:BACKGROUND:Although the subject of many previous studies, the importance of white blood cell (WBC) alloimmunization in granulocyte transfusion therapy has not been settled. In this study, we report the results of the effects of WBC antibodies in the RING (Resolving Infection in Neutropenia with Granulocytes) study, a r...

    journal_title:Transfusion

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/trf.14551

    authors: Price TH,McCullough J,Strauss RG,Ness PM,Hamza TH,Harrison RW,Assmann SF

    更新日期:2018-05-01 00:00:00

  • Transfusion and blood donation on the screen.

    abstract:BACKGROUND:In the 20th century, blood transfusion has become an indispensable therapy in carrying out and improving many medical and surgical applications. Its scope of influence goes well beyond that of medicine, because blood donation, an action with high social significance, is completely connected to progress in th...

    journal_title:Transfusion

    pub_type: 历史文章,杂志文章

    doi:10.1111/j.1537-2995.2007.01634.x

    authors: Danic B,Lefrère JJ

    更新日期:2008-05-01 00:00:00

  • Monitoring for underutilization of RBC components and platelets.

    abstract:BACKGROUND:Monitoring blood transfusion for overutilization is standard practice at most institutions. STUDY DESIGN AND METHODS:This study monitored for underutilization of blood transfusion over a 14-month period, by evaluating patients who had Hb levels that were reported to be <5 g per dL or platelet counts <10 x 1...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2001.41050587.x

    authors: Saxena S,Wehrli G,Makarewicz K,Sartorelli J,Shulman IA

    更新日期:2001-05-01 00:00:00

  • The prevalence of anti-HCV among Chinese voluntary blood donors in Taiwan.

    abstract::In Taiwan, the prevalence of circulating anti-HCV is 2 percent among first-time voluntary Chinese blood donors, 10 percent among donors with elevated ALT levels (greater than 45 IU/L), and higher among older men. The carrier rate for HBsAg was 18.6 percent and the frequency of positive HBV marker(s) (HBsAg, anti-HBc, ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1990.30590296383.x

    authors: Lin-Chu M,Tsai SJ,Watanabe J,Nishioka K

    更新日期:1990-06-01 00:00:00

  • Improvement of platelet storage conditions by using new polyolefin containers.

    abstract:BACKGROUND:Storage of pooled platelet concentrates (PCs) with yields above 3.0 x 10(11) platelets per unit in a 1-L PL-732 polyolefin container for 5 days often results in a drop in pH to below 6.0. Recently, new oxygen-permeable platelet containers (1-L PL-2410, 1-L and 1.5-L Compoflex) have been developed. The maxima...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1997.37597293876.x

    authors: de Wildt-Eggen J,Schrijver JG,Bouter-Valk HJ,Fijnheer R,Bins M,van Prooijen HC

    更新日期:1997-05-01 00:00:00

  • Iron supplementation in female blood donors deferred by copper sulfate screening.

    abstract::Female blood donors with low hematocrit levels detected by copper sulfate screening were selected randomly to receive either 75 mg of iron per day, as ferrous gluconate, or a calcium phosphate placebo. Their ferritin, serum iron, total iron-binding capacity, zinc protoporphyrin, and hemoglobin values, as well as their...

    journal_title:Transfusion

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1537-2995.1988.28588337328.x

    authors: Cable RG,Morse EE,Keltonic J,Kakaiya R,Kiraly T

    更新日期:1988-09-01 00:00:00

  • Cost projections for implementation of safety interventions to prevent transfusion-transmitted Zika virus infection in the United States.

    abstract:BACKGROUND:In August 2016, the Food and Drug Administration advised US blood centers to screen all whole blood and apheresis donations for Zika virus (ZIKV) with an individual-donor nucleic acid test (ID-NAT) or to use approved pathogen reduction technology (PRT). The cost of implementing this guidance nationally has n...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.14164

    authors: Ellingson KD,Sapiano MRP,Haass KA,Savinkina AA,Baker ML,Henry RA,Berger JJ,Kuehnert MJ,Basavaraju SV

    更新日期:2017-06-01 00:00:00

  • The restricted use of IGHV3 superspecies genes in anti-Rh is not limited to hyperimmunized anti-D donors.

    abstract:BACKGROUND:Antibodies produced against the D antigen make use of IGHV genes restricted to the IGHV3 superfamily. These findings are based on the IGHV gene analysis in anti-D-producing B cells from hyperimmunized donors, however, and therefore the restriction might be due to the hyperimmunization. In this study the IGHV...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2006.01047.x

    authors: Dohmen SE,Verhagen OJ,Muit J,Ligthart PC,van der Schoot CE

    更新日期:2006-12-01 00:00:00

  • Associated factors of umbilical cord blood collection quality.

    abstract::After 30 years of hematopoietic stem cell use for various indications, umbilical cord blood is considered as an established source of cells with marrow and postmobilization peripheral blood. The limited number of cells still remains a problematic element restricting their use, especially in adults who require to be gr...

    journal_title:Transfusion

    pub_type: 杂志文章,评审

    doi:10.1111/trf.14447

    authors: Faivre L,Couzin C,Boucher H,Domet T,Desproges A,Sibony O,Bechard M,Vanneaux V,Larghero J,Cras A

    更新日期:2018-02-01 00:00:00

  • How we handled the dextran shortage: an alternative washing or dilution solution for cord blood infusions.

    abstract::Dextran 40 is the main component of the solution used to wash or dilute thawed cord blood unit (CBU) products for stem cell transplant. Dextran 40 became unavailable in the United States as of April 2014. Like many other cellular therapy laboratories in the United States, we found ourselves with limited dextran 40 inv...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.13015

    authors: Reich-Slotky R,Bachegowda LS,Ancharski M,Mendeleyeva L,Rubinstein P,Rennert H,Shore T,van Besien K,Cushing M

    更新日期:2015-06-01 00:00:00

  • Volume of RBCs, 24- and 48-hour posttransfusion survivals, and the lifespan of (51)Cr and biotin-X-N-hydroxysuccinimide (NHS)-labeled autologous baboon RBCs: effect of the anticoagulant and blood pH on (51)Cr and biotin-X-NHS elution in vivo.

    abstract:BACKGROUND:The RBC injury that occurs during collection of the first few milliliters of blood into the pH 5.0 ACD (NIH, Formula A) is referred to as the lesion of collection. The RBC injury was evaluated by labeling the ACD RBCs with (51)Cr and measuring the 24-hour posttransfusion survival. The effect of the acidifica...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2002.00071.x

    authors: Valeri CR,Pivacek LE,Cassidy GP,Ragno G

    更新日期:2002-03-01 00:00:00

  • How to verify patient identity and blood product compatibility using an electronic bedside transfusion system.

    abstract::Transfusion of an incorrect blood component is an important avoidable serious hazard of transfusion resulting from process errors. Our group and others have taken advantage of new technology and developed electronic transfusion systems for safe transfusion practice in a previous studies. They allow the clinical staff ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.16028

    authors: Staples S,O'Callaghan C,Pavord S,Staves J,Murphy MF

    更新日期:2020-09-01 00:00:00

  • Effects of prestorage white cell reduction on platelet aggregate formation and the activation state of platelets and plasma enzyme systems.

    abstract:BACKGROUND:The introduction of prestorage white cell (WBC) reduction in random-donor platelet concentrates in Canada has increased the occurrence of particulate material in PCs. The effects of filtration on platelet activation state and the activation of plasma enzyme systems were assessed. STUDY DESIGN AND METHODS:Pa...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1999.39070724.x

    authors: Devine DV,Bradley AJ,Maurer E,Levin E,Chahal S,Serrano K,Gyongyossy-Issa MI

    更新日期:1999-07-01 00:00:00

  • Etoricoxib-induced immune hemolytic anemia: first case presenting acute kidney failure.

    abstract:BACKGROUND:Etoricoxib is a selective inhibitor of cyclooxygenase 2 used mainly to treat osteoarticular pain. Here, we report the case of a patient who developed acute kidney failure and immune hemolytic anemia after the use of etoricoxib. STUDY DESIGN AND METHODS:An 83-year-old female patient developed immune hemolyti...

    journal_title:Transfusion

    pub_type:

    doi:10.1111/trf.15226

    authors: Burgos Pratx L,Santoro D,Coca Mogro B,Valiente VL,Camino P,Scordo W,Salamone H

    更新日期:2019-05-01 00:00:00

  • Comprehensive survey of red blood cell unit life cycle at a large teaching institution in eastern Canada.

    abstract:BACKGROUND:Recent blood shortages and the potential clinical impact of red blood cell (RBC) age highlight the need to understand blood supply delivery. This study addresses the characteristics and mechanics of RBC unit trafficking and storage across the transfusion service, previously undescribed in the literature. ST...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2009.02375.x

    authors: Cheng CK,Trethewey D,Sadek I

    更新日期:2010-01-01 00:00:00

  • The development of a quantitative enzyme-linked immunosorbent assay to detect human platelet factor 4.

    abstract:BACKGROUND:Platelet factor 4 (PF4) is a marker for in vitro and in vivo tests of platelet (PLT) activation and alpha-granule secretion. PF4 is also a major CXC cytokine released during storage. Cytokines released during PLT storage are a potential cause of nonhemolytic transfusion reactions. Quantitative measurement of...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2005.04243.x

    authors: Schraw T,Whiteheart S

    更新日期:2005-05-01 00:00:00

  • Effects of new brochures on blood donor recruitment and retention.

    abstract:BACKGROUND:Currently, donors may arrive at blood collection sites without prior knowledge of eligibility and deferral criteria. STUDY DESIGN AND METHODS:The effects of distributing newly developed recruitment brochures 2 weeks in advance of blood drives and the provision of brochures on temporary deferral at the takin...

    journal_title:Transfusion

    pub_type: 临床试验,杂志文章

    doi:10.1046/j.1537-2995.1994.34794330012.x

    authors: Gimble JG,Kline L,Makris N,Muenz LR,Friedman LI

    更新日期:1994-07-01 00:00:00

  • Safe fetal platelet genotyping: new developments.

    abstract:BACKGROUND:Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is due to maternal alloimmunization against fetal platelet (PLT) antigens. Antenatal management strategies have been developed to avoid complications such as intracranial hemorrhage. The aim of this study was to set up two reliable, noninvasive fetal gen...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2012.03954.x

    authors: Le Toriellec E,Chenet C,Kaplan C

    更新日期:2013-08-01 00:00:00

  • Incorporation of plasticizer into red cells during storage.

    abstract::The development of flexible plastic blood bags has permitted effective blood component production and therapy. However, the plasticizer di(2-ethylhexyl)phthalate (DEHP), whose toxicity in humans is still undefined, is known to leach from the plastic into stored blood. Despite the availability of bags made of plastics ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1984.24685066808.x

    authors: Rock G,Tocchi M,Ganz PR,Tackaberry ES

    更新日期:1984-11-01 00:00:00

  • Continuous-flow leukapheresis for rapid cytoreduction in leukemia.

    abstract::Three patients with leukemia were treated for acute leukostasis using the continuous-flow cell separator. The first patient, treated with a standard procedure sustained only a 14 per cent decrease in leukocyte count even though 50 X 10(10) leukocytes were removed. A more aggressive approach was taken with the second t...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1980.20480260280.x

    authors: Lane TA

    更新日期:1980-07-01 00:00:00