Abstract:
:Within the UK, the majority of hepatitis A occurs in high risk groups such as men who have sex with men (MSM). It has been estimated that 70% of MSM need immunity to provide adequate herd immunity. We aimed to estimate the proportion of hepatitis A susceptibility in MSM throughout a 10-year period (2010-2019), and explore associated demographic factors. Using our Electronic Patient Record system, we extracted anonymous clinical data between for MSM at their first attendance; including hepatitis A IgG result, age, country of birth and diagnosis of an STI. Overall, 1401/6884(20%) were tested for hepatitis A IgG at their first attendance, with 626/1401 (45%, 95% CI = 42%-47%) showing susceptibility. Testing rates increased between 2010-2019 (OR = 67.79, 95%CI = 39.09-117.60, p = <0.0001); however, susceptibility remained similar (OR = 0.98, 95%CI = 0.33-2.89, p = 0.98). MSM aged 35 and under had significantly higher susceptibility vs MSM aged over 35 (OR 3.4176, 95%CI = 2.71-4.31, p = <0.0001). UK-born had significantly higher susceptibility vs non-UK born (OR 1.5, 95%CI = 1.2147-1.8618, p = 0.0002). Susceptibility of hepatitis A in MSM may be higher than necessary to control future outbreaks. It is important that effective targeting of MSM, particularly young MSM, occur at all levels of healthcare and not solely rely on opportunistic presentation at a sexual health clinic.
journal_name
Int J STD AIDSjournal_title
International journal of STD & AIDSauthors
Fitzpatrick C,Finnerty F,Williams D,Richardson Ddoi
10.1177/0956462420961960subject
Has Abstractpub_date
2020-12-18 00:00:00pages
956462420961960eissn
0956-4624issn
1758-1052pub_type
杂志文章abstract::HIV status awareness is key to prevention, linkage-to-care and treatment. Our study evaluated the accessibility and potential willingness of HIV self-testing among men who have sex with men (MSM) and transgender women in Peru. We surveyed four pharmacy chains in Peru to ascertain the commercial availability of the ora...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462416630674
更新日期:2017-02-01 00:00:00
abstract::Few analytic opportunities have allowed us to evaluate the role that specific sexual acts and male latex condoms play in the acquisition of external anal warts (EAW) using longitudinal data. The acquisition of EAWs occurs from epithelial contact with other HPV-infected surfaces, and hence is dependent upon sexual beha...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,多中心研究
doi:10.1258/0956462053420176
更新日期:2005-03-01 00:00:00
abstract::The objective of this study was to quantitatively measure the nature of concurrent sex partnering in two samples of drug users having large numbers of sex partners. The purpose of this study was to measure concurrent sex partnering and overlap in concurrent sex partners in two samples of drug users in which some or al...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646206776790123
更新日期:2006-05-01 00:00:00
abstract::The aim of this study was to develop and evaluate a simple V3 peptide-based enzyme immunoassay (PEIA) for large-scale serotyping of HIV-1 specimens derived from injecting drug users (IDUs) in the Russian Federation. Two synthetic peptides were evaluated, named P1 (RKSIHIGPGRAFYATGD) and P2 (RTSVRIGPGQVFYKTGD), in an P...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::There is a need for new hypotheses to supplement existing explanations for the observed differences in HIV prevalence between countries and within countries. Due to high levels of viraemia during the initial phase of HIV infection, networks of concurrent regular partnerships in a community could be the determining fac...
journal_title:International journal of STD & AIDS
pub_type: 社论
doi:10.1177/095646249300400501
更新日期:1993-09-01 00:00:00
abstract::Two hundred consecutive patients with herpes zoster attending the skin clinic at the Kilimanjaro Christian Medical Centre (KCMC) were examined and checked for HIV infection. They ranged in age from 10 months to 86 years with the majority in their 20s and 30s. The dermatomes involved were thoracic (97), trigeminal (50)...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462001915804
更新日期:2000-04-01 00:00:00
abstract::Given the disproportionate HIV burden faced by female sex workers FSWs and limited data regarding their engagement in the HIV cascade of care in conflict-affected settings, we characterized the cascade of care and examined associations with new HIV diagnoses and antiretroviral therapy (ART) use in a community-based co...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462418804658
更新日期:2019-03-01 00:00:00
abstract::The aims of this study were to understand the prevalence and correlates of syphilis infection among HIV-positive men who have sex with men (MSM) in Shanghai, China. A total of 200 HIV-positive MSM participants were recruited using "snowball" sampling. Participants were tested for syphilis and completed a one-time ques...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462413512804
更新日期:2014-05-01 00:00:00
abstract::Trichomonas vaginalis (TV) rates in women are increasing and many are asymptomatic. Nucleic acid amplification tests (NAATs) are becoming the 'gold standard' for diagnosis. We aimed to establish our asymptomatic TV rates by testing all women attending Oxfordshire's Sexual Health service, regardless of symptoms, using ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462416649888
更新日期:2017-03-01 00:00:00
abstract::Tetracycline resistant Neisseria gonorrhoeae (TRNG) contain a 25.2 MDa TetM plasmid encoding a 68 KDa cytoplasmic protein which confers high-level tetracycline resistance. The aim of this study was to subtype all TRNG isolated in Scotland between 1992 and 1998. Subtyping was performed by a polymerase chain reaction (P...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462991913204
更新日期:1999-10-01 00:00:00
abstract::We present the case of a 58-year-old HIV-infected patient with adrenal insufficiency after local injection of triamcinolone, most likely due to drug-drug interaction with his ritonavir-boosted antiretroviral therapy (ART). This is the first case of adrenal insufficiency occurring without prior symptoms of Cushing's sy...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462418768689
更新日期:2018-11-01 00:00:00
abstract::The objectives were, first, to determine the sensitivity and specificity of the Osmetech Microbial Analyser (OMA) for the diagnosis of bacterial vaginosis (BV) and, secondly, to determine the factors that interfere with the performance of the test. Women presenting to a genitourinary medicine clinic underwent routine ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646203321156881
更新日期:2003-02-01 00:00:00
abstract::In Latin America, men who have sex with men (MSM) remain disproportionately impacted by HIV. Pre-exposure prophylaxis (PrEP) is an effective HIV prevention tool and has been FDA approved in the United States since 2012, but no Latin American state, with the recent exception of Brazil, has implemented PrEP guidelines. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462419825944
更新日期:2019-05-01 00:00:00
abstract::The prevalence of viral and bacterial sexually transmitted diseases were studied in 101 men attending a dermatovenereal outpatient clinic in Mogadishu. A control group of 103 healthy adult men were included for the serological part of the study. Serological markers of hepatitis B virus (HBV), human immunodeficiency vi...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249000100206
更新日期:1990-03-01 00:00:00
abstract::The management and outcome of all cases of gonorrhoea which presented to a south London genitourinary medicine clinic during 1999 were assessed and compared with published national guidelines. The incidence of penicillin resistance was calculated, as was the rate of co-infection with chlamydia and trichomonas. Informa...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646203322301095
更新日期:2003-09-01 00:00:00
abstract::Little information is available on the prevalence of herpes simplex type-2 (HSV-2) antibodies among groups at potential high risk of HIV in Asia. This study was carried out to determine the prevalence of HSV-2 antibodies and correlates of HSV-2 infection in female sex workers (FSWs) in border provinces of Vietnam. Nin...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646206778691176
更新日期:2006-11-01 00:00:00
abstract::We investigated our patients' preferences for weekend services at the same time as commencing a new Saturday clinic. Patients were asked for their views on weekend services: 374 questionnaires were returned; 210 (56%) from women and 164 (44%) from men. Saturday services were rated as more important than Sunday service...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009208
更新日期:2010-04-01 00:00:00
abstract::Ninety women who were HIV antibody positive attended the genitourinary medicine clinics of East Riverside up to May 1990. Seventy-five of these women (83%) were examined for co-existent sexually transmitted disease (STD) at presentation. The prevalence of STD in these women was compared to the incidence of STD in all ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249100200312
更新日期:1991-05-01 00:00:00
abstract::The potential for drug-drug interactions (DDIs) between direct oral anticoagulants and antiretroviral therapy (ART) is vast. Ritonavir and cobicistat are used as pharmacokinetic enhancers with either concurrent protease inhibitors or the integrase strand transfer inhibitor, elvitegravir, to optimize therapeutic concen...
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pub_type: 杂志文章
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abstract::Despite many reports of HIV-infected African children who have HIV-uninfected mothers, little is known about the extent and modes of horizontal HIV transmission in African children. We estimated the extent of horizontal HIV transmission in Swazi children by comparing child and mother HIV statuses in the 2006-2007 Swaz...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
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abstract::We determined the retention rate of patients infected with HIV who resumed care after being tracked at the Infectious Diseases Clinic (IDC) in Kampala, Uganda. Between April 2011 and September 2013, patients who missed their clinic appointment for 8-90 days were tracked, and those who returned to the clinic within 120...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462414529098
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abstract::Progression of lipodystrophy syndrome is a big challenge in HIV treatment. Nowadays, fat loss at the lower part of buttocks has become another problem as patients have started to complain that it is painful to be seated for a long time and/or on hard surfaces. We developed a method for buttock lipoatrophy treatment wi...
journal_title:International journal of STD & AIDS
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abstract::This cross-sectional study assessed beliefs about highly active antiretroviral therapy (HAART) and their association with reported adherence to HAART among 109 HIV-positive patients receiving HAART while attending an ambulatory care clinic in Brighton, UK. Patients' beliefs about the necessity for and concerns about H...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646204322637245
更新日期:2004-01-01 00:00:00
abstract::We report the case of a patient with a large Buschke-Lowenstein tumour which had previously recurred following local excision. A preferred treatment modality for this rare variant of human papillomavirus has not been clearly defined. Treatment with chemo-radiotherapy in this case resulted in complete resolution of the...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009012
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abstract::We present the updated British Association for Sexual Health and HIV guidelines for HIV post-exposure prophylaxis following sexual exposure (PEPSE). This document includes a review of the current data to support the use of PEPSE, considers how to calculate the risks of infection after a potential exposure, and provide...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
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abstract::Prior research indicates that injection drug users forget substantial proportions of their injection partners when asked to recall them. Such under-reporting hampers both ascertainment of the injection networks that underlie transmission of blood-borne pathogens and contact-tracing efforts for disease control. We repo...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
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abstract::The persistent sexual arousal syndrome (PSAS) is a newly described entity where women become involuntarily aroused genitally for extended periods in time in the absence of sexual desire. Genital vasoengorgement and oedema have been observed. These women are found to be usually very distressed. The cause of the syndrom...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
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abstract::The current cervical screening guidelines lay the duty of care of women under 25 years of age on genitourinary (GU) medicine clinics. To date there has not been an extensive review of cervical cytology results sourced from GU medicine departments. We reviewed the annual reports of the cervical screening programme, wit...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
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abstract::The efficacy of oral azithromycin (500 mg daily for 10 days or 500 mg on alternate days for 11 days) in 100 patients with seropositive syphilis was studied. Clinical manifestations regressed more rapidly in azithromycin-treated patients compared with patients who received erythromycin or penicillin, and there was also...
journal_title:International journal of STD & AIDS
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abstract::Chylous ascites related to Mycobacterium avium complex (MAC) in HIV-infected patients is rare, with only six cases reported in the English literature. We report a series of six cases from a single institution. During the past six years, chylous ascites was diagnosed in six (35%) of 17 AIDS patients, all of whom had pr...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2008.008275
更新日期:2009-04-01 00:00:00