Hepatitis A susceptibility in newly attending men who have sex with men to an urban sexual health centre.

Abstract:

:Within the UK, the majority of hepatitis A occurs in high risk groups such as men who have sex with men (MSM). It has been estimated that 70% of MSM need immunity to provide adequate herd immunity. We aimed to estimate the proportion of hepatitis A susceptibility in MSM throughout a 10-year period (2010-2019), and explore associated demographic factors. Using our Electronic Patient Record system, we extracted anonymous clinical data between for MSM at their first attendance; including hepatitis A IgG result, age, country of birth and diagnosis of an STI. Overall, 1401/6884(20%) were tested for hepatitis A IgG at their first attendance, with 626/1401 (45%, 95% CI = 42%-47%) showing susceptibility. Testing rates increased between 2010-2019 (OR = 67.79, 95%CI = 39.09-117.60, p = <0.0001); however, susceptibility remained similar (OR = 0.98, 95%CI = 0.33-2.89, p = 0.98). MSM aged 35 and under had significantly higher susceptibility vs MSM aged over 35 (OR 3.4176, 95%CI = 2.71-4.31, p = <0.0001). UK-born had significantly higher susceptibility vs non-UK born (OR 1.5, 95%CI = 1.2147-1.8618, p = 0.0002). Susceptibility of hepatitis A in MSM may be higher than necessary to control future outbreaks. It is important that effective targeting of MSM, particularly young MSM, occur at all levels of healthcare and not solely rely on opportunistic presentation at a sexual health clinic.

journal_name

Int J STD AIDS

authors

Fitzpatrick C,Finnerty F,Williams D,Richardson D

doi

10.1177/0956462420961960

subject

Has Abstract

pub_date

2020-12-18 00:00:00

pages

956462420961960

eissn

0956-4624

issn

1758-1052

pub_type

杂志文章
  • HIV self-testing in Peru: questionable availability, high acceptability but potential low linkage to care among men who have sex with men and transgender women.

    abstract::HIV status awareness is key to prevention, linkage-to-care and treatment. Our study evaluated the accessibility and potential willingness of HIV self-testing among men who have sex with men (MSM) and transgender women in Peru. We surveyed four pharmacy chains in Peru to ascertain the commercial availability of the ora...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1177/0956462416630674

    authors: Bustamante MJ,Konda KA,Joseph Davey D,León SR,Calvo GM,Salvatierra J,Brown B,Caceres CF,Klausner JD

    更新日期:2017-02-01 00:00:00

  • How condom use, number of receptive anal intercourse partners and history of external genital warts predict risk for external anal warts.

    abstract::Few analytic opportunities have allowed us to evaluate the role that specific sexual acts and male latex condoms play in the acquisition of external anal warts (EAW) using longitudinal data. The acquisition of EAWs occurs from epithelial contact with other HPV-infected surfaces, and hence is dependent upon sexual beha...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章,多中心研究

    doi:10.1258/0956462053420176

    authors: Wiley DJ,Harper DM,Elashoff D,Silverberg MJ,Kaestle C,Cook RL,Heilemann M,Johnson L

    更新日期:2005-03-01 00:00:00

  • An investigation of concurrent sex partnering in two samples of drug users having large numbers of sex partners.

    abstract::The objective of this study was to quantitatively measure the nature of concurrent sex partnering in two samples of drug users having large numbers of sex partners. The purpose of this study was to measure concurrent sex partnering and overlap in concurrent sex partners in two samples of drug users in which some or al...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1258/095646206776790123

    authors: Williams ML,Ross MW,Atkinson J,Bowen A,Klovdahl A,Timpson SC

    更新日期:2006-05-01 00:00:00

  • Serological approaches to subtyping of HIV-1 in injecting drug users in Russia: evidence of subtype homogeneity at the main sites of the epidemic.

    abstract::The aim of this study was to develop and evaluate a simple V3 peptide-based enzyme immunoassay (PEIA) for large-scale serotyping of HIV-1 specimens derived from injecting drug users (IDUs) in the Russian Federation. Two synthetic peptides were evaluated, named P1 (RKSIHIGPGRAFYATGD) and P2 (RTSVRIGPGQVFYKTGD), in an P...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:

    authors: Bobkova MR,Kazennova EV,Selimova LM,Buravtsova EV,Lister S,Prilipov AG,Weber JN,Pokrovsky VV,Bobkov AF

    更新日期:2001-01-01 00:00:00

  • Concurrent partnerships could cause AIDS epidemics.

    abstract::There is a need for new hypotheses to supplement existing explanations for the observed differences in HIV prevalence between countries and within countries. Due to high levels of viraemia during the initial phase of HIV infection, networks of concurrent regular partnerships in a community could be the determining fac...

    journal_title:International journal of STD & AIDS

    pub_type: 社论

    doi:10.1177/095646249300400501

    authors: Hudson CP

    更新日期:1993-09-01 00:00:00

  • Herpes zoster and HIV infection in Tanzania.

    abstract::Two hundred consecutive patients with herpes zoster attending the skin clinic at the Kilimanjaro Christian Medical Centre (KCMC) were examined and checked for HIV infection. They ranged in age from 10 months to 86 years with the majority in their 20s and 30s. The dermatomes involved were thoracic (97), trigeminal (50)...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1258/0956462001915804

    authors: Naburi AE,Leppard B

    更新日期:2000-04-01 00:00:00

  • High burden of previously undiagnosed HIV infections and gaps in HIV care cascade for conflict-affected female sex workers in northern Uganda.

    abstract::Given the disproportionate HIV burden faced by female sex workers FSWs and limited data regarding their engagement in the HIV cascade of care in conflict-affected settings, we characterized the cascade of care and examined associations with new HIV diagnoses and antiretroviral therapy (ART) use in a community-based co...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1177/0956462418804658

    authors: Goldenberg SM,Muzaaya G,Akello M,Braschel M,Birungi J,Shannon K

    更新日期:2019-03-01 00:00:00

  • Prevalence of syphilis infection and associations with sexual risk behaviours among HIV-positive men who have sex with men in Shanghai, China.

    abstract::The aims of this study were to understand the prevalence and correlates of syphilis infection among HIV-positive men who have sex with men (MSM) in Shanghai, China. A total of 200 HIV-positive MSM participants were recruited using "snowball" sampling. Participants were tested for syphilis and completed a one-time ques...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1177/0956462413512804

    authors: He H,Wang M,Zaller N,Wang J,Song D,Qu Y,Sui X,Dong Z,Operario D,Zhang H

    更新日期:2014-05-01 00:00:00

  • Detecting asymptomatic Trichomonas vaginalis in females using the BD ProbeTec™ Trichomonas vaginalis Qx nucleic acid amplification test.

    abstract::Trichomonas vaginalis (TV) rates in women are increasing and many are asymptomatic. Nucleic acid amplification tests (NAATs) are becoming the 'gold standard' for diagnosis. We aimed to establish our asymptomatic TV rates by testing all women attending Oxfordshire's Sexual Health service, regardless of symptoms, using ...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1177/0956462416649888

    authors: Lord E,Newnham T,Dorrell L,Jesuthasan G,Clarke L,Jeffery K,Sherrard J

    更新日期:2017-03-01 00:00:00

  • Subtyping of high-level plasmid-mediated tetracycline resistant Neisseria gonorrhoeae isolated in Scotland between 1992 and 1998.

    abstract::Tetracycline resistant Neisseria gonorrhoeae (TRNG) contain a 25.2 MDa TetM plasmid encoding a 68 KDa cytoplasmic protein which confers high-level tetracycline resistance. The aim of this study was to subtype all TRNG isolated in Scotland between 1992 and 1998. Subtyping was performed by a polymerase chain reaction (P...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1258/0956462991913204

    authors: Beattie T,Moyes A,Patrizio C,Young H

    更新日期:1999-10-01 00:00:00

  • Adrenal insufficiency due to ritonavir-triamcinolone drug-drug interaction without preceding Cushing's syndrome.

    abstract::We present the case of a 58-year-old HIV-infected patient with adrenal insufficiency after local injection of triamcinolone, most likely due to drug-drug interaction with his ritonavir-boosted antiretroviral therapy (ART). This is the first case of adrenal insufficiency occurring without prior symptoms of Cushing's sy...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1177/0956462418768689

    authors: Noe S,Jaeger H,Heldwein S

    更新日期:2018-11-01 00:00:00

  • Evaluation of a novel diagnostic test for bacterial vaginosis: 'the electronic nose'.

    abstract::The objectives were, first, to determine the sensitivity and specificity of the Osmetech Microbial Analyser (OMA) for the diagnosis of bacterial vaginosis (BV) and, secondly, to determine the factors that interfere with the performance of the test. Women presenting to a genitourinary medicine clinic underwent routine ...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1258/095646203321156881

    authors: Hay P,Tummon A,Ogunfile M,Adebiyi A,Adefowora A

    更新日期:2003-02-01 00:00:00

  • The role of sexual risk behaviors on PrEP awareness and interest among men who have sex with men in Latin America.

    abstract::In Latin America, men who have sex with men (MSM) remain disproportionately impacted by HIV. Pre-exposure prophylaxis (PrEP) is an effective HIV prevention tool and has been FDA approved in the United States since 2012, but no Latin American state, with the recent exception of Brazil, has implemented PrEP guidelines. ...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1177/0956462419825944

    authors: Edeza A,Galarraga O,Novak D,Mayer K,Rosenberger J,Mimiaga M,Biello K

    更新日期:2019-05-01 00:00:00

  • Sexually transmitted diseases in men in Mogadishu, Somalia.

    abstract::The prevalence of viral and bacterial sexually transmitted diseases were studied in 101 men attending a dermatovenereal outpatient clinic in Mogadishu. A control group of 103 healthy adult men were included for the serological part of the study. Serological markers of hepatitis B virus (HBV), human immunodeficiency vi...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1177/095646249000100206

    authors: Ismail SO,Ahmed HJ,Grillner L,Hederstedt B,Issa A,Bygdeman SM

    更新日期:1990-03-01 00:00:00

  • Gonorrhoea in a south London genitourinary medicine department.

    abstract::The management and outcome of all cases of gonorrhoea which presented to a south London genitourinary medicine clinic during 1999 were assessed and compared with published national guidelines. The incidence of penicillin resistance was calculated, as was the rate of co-infection with chlamydia and trichomonas. Informa...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1258/095646203322301095

    authors: Newell A,Herbert E,Vigus J,Grieg A,Rodgers ME

    更新日期:2003-09-01 00:00:00

  • HSV-2 antibodies in female sex workers in Vietnam.

    abstract::Little information is available on the prevalence of herpes simplex type-2 (HSV-2) antibodies among groups at potential high risk of HIV in Asia. This study was carried out to determine the prevalence of HSV-2 antibodies and correlates of HSV-2 infection in female sex workers (FSWs) in border provinces of Vietnam. Nin...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1258/095646206778691176

    authors: O'Farrell N,Thuong NV,Nghia KV,Tram LT,Long NT

    更新日期:2006-11-01 00:00:00

  • Something for the weekend! Saturday services - what do patients want and what do they need?

    abstract::We investigated our patients' preferences for weekend services at the same time as commencing a new Saturday clinic. Patients were asked for their views on weekend services: 374 questionnaires were returned; 210 (56%) from women and 164 (44%) from men. Saturday services were rated as more important than Sunday service...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1258/ijsa.2009.009208

    authors: Challenor R,Warwick Z

    更新日期:2010-04-01 00:00:00

  • Sexually transmitted diseases in HIV-1 seropositive women at presentation.

    abstract::Ninety women who were HIV antibody positive attended the genitourinary medicine clinics of East Riverside up to May 1990. Seventy-five of these women (83%) were examined for co-existent sexually transmitted disease (STD) at presentation. The prevalence of STD in these women was compared to the incidence of STD in all ...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1177/095646249100200312

    authors: Kell PD,Barton SE,Summerbell CD,Lawrence AG

    更新日期:1991-05-01 00:00:00

  • Ritonavir- or cobicistat-boosted antiretroviral therapy and direct oral anticoagulants: A case for apixaban.

    abstract::The potential for drug-drug interactions (DDIs) between direct oral anticoagulants and antiretroviral therapy (ART) is vast. Ritonavir and cobicistat are used as pharmacokinetic enhancers with either concurrent protease inhibitors or the integrase strand transfer inhibitor, elvitegravir, to optimize therapeutic concen...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1177/0956462419832099

    authors: Nisly SA,Stevens BN

    更新日期:2019-06-01 00:00:00

  • Horizontally-acquired HIV infection in Kenyan and Swazi children.

    abstract::Despite many reports of HIV-infected African children who have HIV-uninfected mothers, little is known about the extent and modes of horizontal HIV transmission in African children. We estimated the extent of horizontal HIV transmission in Swazi children by comparing child and mother HIV statuses in the 2006-2007 Swaz...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1258/ijsa.2009.009204

    authors: Okinyi M,Brewer DD,Potterat JJ

    更新日期:2009-12-01 00:00:00

  • Patients who return to care after tracking remain at high risk of attrition: experience from a large HIV clinic, Uganda.

    abstract::We determined the retention rate of patients infected with HIV who resumed care after being tracked at the Infectious Diseases Clinic (IDC) in Kampala, Uganda. Between April 2011 and September 2013, patients who missed their clinic appointment for 8-90 days were tracked, and those who returned to the clinic within 120...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1177/0956462414529098

    authors: Nakiwogga-Muwanga A,Musaazi J,Katabira E,Worodria W,Talisuna SA,Colebunders R

    更新日期:2015-01-01 00:00:00

  • Soft tissue augmentation with PMMA-microspheres for the treatment of HIV-associated buttock lipodystrophy.

    abstract::Progression of lipodystrophy syndrome is a big challenge in HIV treatment. Nowadays, fat loss at the lower part of buttocks has become another problem as patients have started to complain that it is painful to be seated for a long time and/or on hard surfaces. We developed a method for buttock lipoatrophy treatment wi...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1177/0956462414536878

    authors: Serra MS,Gonçalves LZ,Ramos-e-Silva M

    更新日期:2015-03-01 00:00:00

  • Doubts about necessity and concerns about adverse effects: identifying the types of beliefs that are associated with non-adherence to HAART.

    abstract::This cross-sectional study assessed beliefs about highly active antiretroviral therapy (HAART) and their association with reported adherence to HAART among 109 HIV-positive patients receiving HAART while attending an ambulatory care clinic in Brighton, UK. Patients' beliefs about the necessity for and concerns about H...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1258/095646204322637245

    authors: Horne R,Buick D,Fisher M,Leake H,Cooper V,Weinman J

    更新日期:2004-01-01 00:00:00

  • Successful treatment of a large Buschke-Lowenstein tumour with chemo-radiotherapy.

    abstract::We report the case of a patient with a large Buschke-Lowenstein tumour which had previously recurred following local excision. A preferred treatment modality for this rare variant of human papillomavirus has not been clearly defined. Treatment with chemo-radiotherapy in this case resulted in complete resolution of the...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1258/ijsa.2009.009012

    authors: Armstrong N,Foley G,Wilson J,Finan P,Sebag-Montefiore D

    更新日期:2009-10-01 00:00:00

  • UK guideline for the use of HIV Post-Exposure Prophylaxis Following Sexual Exposure, 2015.

    abstract::We present the updated British Association for Sexual Health and HIV guidelines for HIV post-exposure prophylaxis following sexual exposure (PEPSE). This document includes a review of the current data to support the use of PEPSE, considers how to calculate the risks of infection after a potential exposure, and provide...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1177/0956462416641813

    authors: Cresswell F,Waters L,Briggs E,Fox J,Harbottle J,Hawkins D,Murchie M,Radcliffe K,Rafferty P,Rodger A,Fisher M

    更新日期:2016-08-01 00:00:00

  • Improved injection network ascertainment with supplementary elicitation techniques.

    abstract::Prior research indicates that injection drug users forget substantial proportions of their injection partners when asked to recall them. Such under-reporting hampers both ascertainment of the injection networks that underlie transmission of blood-borne pathogens and contact-tracing efforts for disease control. We repo...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1258/ijsa.2007.007167

    authors: Brewer DD,Hagan H,Hough ES

    更新日期:2008-03-01 00:00:00

  • Persistent genital arousal in women -- a new syndrome entity.

    abstract::The persistent sexual arousal syndrome (PSAS) is a newly described entity where women become involuntarily aroused genitally for extended periods in time in the absence of sexual desire. Genital vasoengorgement and oedema have been observed. These women are found to be usually very distressed. The cause of the syndrom...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章,评审

    doi:10.1258/095646206776253480

    authors: Goldmeier D,Leiblum SR

    更新日期:2006-04-01 00:00:00

  • A review of cervical cytology in genitourinary medicine clinics in England between 1997 and 2008.

    abstract::The current cervical screening guidelines lay the duty of care of women under 25 years of age on genitourinary (GU) medicine clinics. To date there has not been an extensive review of cervical cytology results sourced from GU medicine departments. We reviewed the annual reports of the cervical screening programme, wit...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章,评审

    doi:10.1258/ijsa.2009.009122

    authors: Markos AR

    更新日期:2009-10-01 00:00:00

  • Treatment of syphilis with azithromycin.

    abstract::The efficacy of oral azithromycin (500 mg daily for 10 days or 500 mg on alternate days for 11 days) in 100 patients with seropositive syphilis was studied. Clinical manifestations regressed more rapidly in azithromycin-treated patients compared with patients who received erythromycin or penicillin, and there was also...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1258/0956462961917249

    authors: Mashkilleyson AL,Gomberg MA,Mashkilleyson N,Kutin SA

    更新日期:1996-01-01 00:00:00

  • Chylous ascites: a late complication of intra-abdominal Mycobacterium avium complex immune reconstitution syndrome in HIV-infected patients.

    abstract::Chylous ascites related to Mycobacterium avium complex (MAC) in HIV-infected patients is rare, with only six cases reported in the English literature. We report a series of six cases from a single institution. During the past six years, chylous ascites was diagnosed in six (35%) of 17 AIDS patients, all of whom had pr...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1258/ijsa.2008.008275

    authors: Phillips P,Lee JK,Wang C,Yoshida E,Lima VD,Montaner J

    更新日期:2009-04-01 00:00:00