Development of a 1-step cell-based assay for cost-effective screening of antiviral drugs for vaccinia virus.

Abstract:

:We report a 1-step assay to screen antiviral substances combining the simultaneous application of cells, virus sample, and drug to 96-well plates. The results were obtained within 26 h when vaccinia virus plaques were counted or virus-induced cytopathic effect was measured. This fast cost-effective procedure may be used for other cytopathic viruses and is suitable to 1st screening tests.

authors

Jesus DM,Santos ES,Schnellrath LC,Damaso CR

doi

10.1016/j.diagmicrobio.2009.03.015

subject

Has Abstract

pub_date

2009-07-01 00:00:00

pages

350-3

issue

3

eissn

0732-8893

issn

1879-0070

pii

S0732-8893(09)00106-0

journal_volume

64

pub_type

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