Abstract:
OBJECTIVE:The main justification of this study was to describe our experience in neonatal screening and to define the prevalence of the diseases included in the neonatal screening program in Andalusia, among which are congenital hypothyroidism, expanded screening (aminoacidopathies, mitochondrial beta-oxidation defects and organic acidurias), cystic fibrosis, and screening for sickle cell anemia. METHODS:The study was carried out in the Metabolopathies Unit of the Virgen del Rocío Hospital in Seville with samples of newborns from Western Andalusia (Cádiz, Córdoba, Huelva and Seville) and autonomous city of Ceuta. A total of 435,141 newborns were studied (from the period from April 1st 2009 to December 31st 2019) to rule out congenital hypothyroidism and expanded screening; 378,306 for cystic fibrosis from May 1st 2011 to the same date described above. Finally, sickle cell anemia screening was included, which comprised a total of 55,576 newborns from November 26th, 2018 to the same period as the previous ones. Statistical analysis was performed using IBM SPSS software (version 22, SPSS INC., USA). RESULTS:The study revealed a prevalence of 1:1565 newborns for congenital hypothyroidism, 1:1532 newborns for extended screening, 1:6.878 newborns for cystic fibrosis, and a 1:11.115 newborns for sickle cell disease. CONCLUSIONS:The neonatal screening program allows a large number of newborns to benefit from the early detection of certain serious congenital diseases. This aim improves the morbidity and mortality of those who suffer from them. OBJETIVO:La principal justificación del trabajo fue describir nuestra experiencia en cribado neonatal y definir la prevalencia de cada una de las enfermedades incluidas en el programa de cribado neonatal de Andalucía, entre las que se encuentran el hipotiroidismo congénito, cribado ampliado expandido (aminoacidopatías, defectos de la beta-oxidación mitocondrial y acidurias orgánicas), fibrosis quística y enfermedad de células falciformes. METODOS:El estudio se realizó en la Unidad del Laboratorio de Metabolopatías del Hospital Universitario Virgen del Rocío de Sevilla con muestras de recién nacidos de Andalucía Occidental (Cádiz, Córdoba, Huelva y Sevilla) y la ciudad autónoma de Ceuta. Para descartar hipotiroidismo congénito y cribado ampliado expandido se estudiaron un total de 435.141 recién nacidos, con fecha de inicio el 1 de abril de 2009. El cribado de fibrosis quística comenzó el 1 de mayo de 2011, siendo estudiados un total de 378.306 recién nacidos. Por último, el 26 de noviembre de 2018 se incorporó el cribado de anemia de células falciformes, que comprendió un total de 55.576 recién nacidos. La fecha fin de estudio fue el 31 de diciembre de 2019 para todas las patologías descritas anteriormente. El análisis estadístico se realizó usando el software IBM SPSS (versión 22, SPSS INC., EEUU). RESULTADOS:El estudio reveló una prevalencia de 1:1.565 recién nacidos para hipotiroidismo congénito, 1:1.532 para cribado ampliado expandido, 1:6.878 para fibrosis quística y 1:11.115 recién nacidos para enfermedad de células falciformes. CONCLUSIONES:El programa de cribado neonatal permite que se beneficien gran número de recién nacidos en la detección precoz de determinadas enfermedades congénitas graves y, con ello, mejora la morbimortalidad de aquellos que las padecen.
journal_name
Rev Esp Salud Publicajournal_title
Revista espanola de salud publicaauthors
Delgado-Pecellín C,Álvarez Ríos I,Bueno Delgado MDA,Jiménez Jambrina MM,Quintana Gallego ME,Ruiz Salas P,Marcos Luque I,Melguizo Madrid Esubject
Has Abstractpub_date
2020-12-16 00:00:00eissn
1135-5727issn
2173-9110journal_volume
94pub_type
杂志文章abstract:OBJECTIVE:The Basque Government (Spain) approved a population based Colorectal Cancer Screening Programme in 2008 with its base on Primary Healthcare. Since then, a coverage of 100% of the population and an average participation rate of 68.4% have been achieved. General Practitioners and nurses play a central role on i...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:2021-01-26 00:00:00
abstract::Performance measurement, in their different meanings--either balance scorecard or outputs measurement--have become an essential tool in today's organizations (World-Class organizations) to improve service quality and reduce costs. This paper presents a performance measurement system for the hospital supply chain. The ...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:2001-07-01 00:00:00
abstract:BACKGROUND:Given that there are different ways of setting out clinical test results, this study is aimed at ascertaining whether the way in which these results are set out has any bearing on the intention to prescribed on the part of Primary Care physicians. METHODS:Randomized, multi-center cross-study. Following a ra...
journal_title:Revista espanola de salud publica
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1590/s1135-57272004000100004
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Social class has commonly been defined by the type of employment and it is assessed as a categorical variable. However, this approach has a number of drawbacks. The objective of this article is to develop and validate a readily standardizable quantitative indicator of social class and to show its ability to ...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
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abstract:BACKGROUND:The gradual increase of women in the health professions does not correspond with her presence in positions of power. Given that professional colleges have an essential role in the representation and professional regulation, arises as an aim to describe the presence of women in the managerial structures of th...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
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abstract:BACKGROUND:Over at least the past ten years, measures aimed at health promotion and prevention among young adults and teenagers have been being implemented from different public institutions and, in a certain sense, on a sectorial basis. The overall objective is to assess how the different measures carried out by diffe...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:2002-09-01 00:00:00
abstract:BACKGROUND:The consumption of butterfish is spreading in our country; if appropriate standards of conservation and preparation of this type of food are not met may cause poisoning. The objective is to describe an outbreak of histamine poisoning and double cerous esters after consumption butterfish. METHODS:A descripti...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:10.4321/S1135-57272015000100011
更新日期:2015-01-01 00:00:00
abstract::The pandemic influenza (H1N1) 2009 raised a number of issues, of which we address the following: Why did between 25 and 30% of severe influenza cases show no obvious risk factor? We hypothesize that an element that can contribute to the answer are host genetic risk factors involved in poor disease progression. Several...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:10.1590/S1135-57272011000100004
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:The term "Patient Reported Outcomes" (PRO) is defined as any result assessed directly by the patient and based on his perception of the illness and its treatment. The scope of the study is to determine and compare the use of PRO measures with other types of effectiveness endpoints in the summary of the produ...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:10.4321/S1135-57272014000500006
更新日期:2014-10-01 00:00:00
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journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:10.1590/s1135-57272004000400004
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abstract:BACKGROUND:In undertaking a Minimum Basic Data Set (MBDS) of hospital discharges has to be done for all hospitals. It depends on the good function of the Medical Records Archive. The objective of this study is the continuous evaluation of the quality of the Medical Records Archive via Control Diagrams statistical techn...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:10.1590/S1135-57272011000400008
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:The province of Havana City, the capital and most densely populated city in Cuba, totals around 27% of the new cases of tuberculosis. This article is for the purpose of describing the distribution and trend of the tuberculosis cases rates from 1986 to 1998, by municipalities and age groups in this province. ...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:2000-09-01 00:00:00
abstract:OBJECTIVE:Terminal patients and their relatives must know their real situation, and be treated according to the principle of autonomy, to establish therapeutic objectives adapted each one, according to their needs and decisions. The objective of this study is to identify the sufficient existence of records in the Medic...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:2020-05-05 00:00:00
abstract:BACKGROUND:To identify epidemiological aspects of the osteoporotic hip fractures (OHF) in the province of Zamora in 1993, and the basic and standardised accumulative incidence rates amongst the Spanish population. METHODS:215 OHF cases were studied in the province throughout 1993, 203 were admitted to hospital, 188 of...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:1997-07-01 00:00:00
abstract:BACKGROUND:In the context of budgetary difficulties, the estimation of non safety costs is an additional tool that may be useful in the decision making process of the health system as well as to improve the health care management. Until now there is no study that has estimated the costs of non safety in Spain in an int...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:10.4321/S1135-57272013000300008
更新日期:2013-05-01 00:00:00
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journal_title:Revista espanola de salud publica
pub_type: 杂志文章,评审
doi:10.4321/S1135-57272014000600012
更新日期:2014-11-01 00:00:00
abstract::The Millennium Development Goals (MDGs) are now at the midterm of their target period, as 2015 is the date scheduled by the United Nations Organisation (UN) for their attainment. The purpose of this article is to review the current situation of the MDGs worldwide and to analyse the barriers which are preventing them f...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章,评审
doi:10.1590/s1135-57272008000500002
更新日期:2008-09-01 00:00:00
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journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:2020-08-27 00:00:00
abstract:OBJECTIVE:Hand hygiene (HH) is essential for the prevention of health care-associated infections (HAIs). Compliance rates documented in Spain and internationally are low, although improvement is possible using some strategies and training. The aim of this study was to know the evolution of the adherence to the 5 moment...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:2020-07-22 00:00:00
abstract::The results of the meningococcal vaccination campaign carried out in Cantabria in February-March 1997 are presented. In the short term, the campaign reduced the rate of incidence in the risk group from 21.33/100,000 in the previous 12 months, to zero in the 12 months following the campaign. In the medium term (2 and a...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:2000-07-01 00:00:00
abstract:BACKGROUND:The Medical Death Certificate and the Death Statistics Bulletin were unified and implemented in the year 2009 in Spain. National statistics detected an unusual increase for diabetes mellitus (DM) and hypertensive disease (HT) deaths in 2009, in relation to previous years trend.The objective is to study the d...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:10.1590/S1135-57272012000300003
更新日期:2012-05-01 00:00:00
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journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:2020-11-03 00:00:00
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journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:10.1590/s1135-57272006000100006
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:This a prospective study of the incidence, etiology and epidemiological profile of human brucellosis in the regions of Pallars Jussà y Sobirà (Lleida) for the 1995-1998 period. METHODS:Fifty-five patients diagnosed as having brucellosis were studied. Information was recorded regarding the gender, age, town ...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Knowing Influenza absenteeism in the educational environment. Making health education in the same medium. METHODS:Among other actions carried out in the pandemic plan, the absences were monitored by flu-like symptoms in children from kindergarten, primary and secondary public schools and reached epidemiolog...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:10.1590/s1135-57272010000500019
更新日期:2010-09-01 00:00:00
abstract:OBJECTIVE:The partner notification is one of the main activities of epidemiological surveillance in Public Health. The primary objective was to estimate the compliance of the partner notification by health professionals who reported sexually transmitted diseases (HIV, Gonorrhoea, Syphilis and Chlamydia) during 2017 in ...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:2019-12-02 00:00:00
abstract:OBJECTIVE:Only very few instruments have been developed to assess sexual knowledge and practices. Most of the research to date has been carried out with adolescent samples, but not with university students, who are also at a particularly risky stage. The aim of this study was to design and validate a brief questionnair...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:2018-06-01 00:00:00
abstract:OBJECTIVE:One of the fist lines of action of the National Plan against Antibiotic Resistance (PRAN) is to monitor the use of antibiotics as a fundamental basis for the fight against resistance. In order to know the antibiotic prescription habits, we pretended to describe the outpatient prescription of systemic antibiot...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:2020-09-25 00:00:00
abstract:BACKGROUND:Human immuno-deficiency virus (HIV) infection is one of the leading public health problems in our country. Preventive education has shown itself to be a useful tool for curtailing this disease. The objective of this study is that of assessing the effectiveness of a preventive intervention at the Secondary Sc...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:2003-05-01 00:00:00
abstract:BACKGROUND:Even if there is a wide consensus on the concept of a dependent individual, in practice national valuation systems produce completely different results. The objective in this work is to compare the application of different valuation scales for dependency on the Spanish population and to identify the differen...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:10.1590/s1135-57272009000300004
更新日期:2009-05-01 00:00:00