Abstract:
:The advent of moderate dilatations in ascending aortas is often accompanied by structural modifications of the main components of the aortic tissue, elastin and collagen. In this study, we have undertaken an approach based on FTIR microscopy coupled to a curve-fitting procedure to analyze secondary structure modifications in these proteins in human normal and pathological aortic tissues. We found that the outcome of the aortic pathology is strongly influenced by these proteins, which are abundant in the media of the aortic wall, and that the advent of an aortic dilatation is generally accompanied by a decrease of parallel beta-sheet structures. Elastin, essentially composed of beta-sheet structures, seems to be directly related to these changes and therefore indicative of the elastic alteration of the aortic wall. Conventional microscopy and confocal fluorescence microscopy were used to compare FTIR microscopy results with the organization of the elastic fibers present in the tissues. This in-vitro study on 6 patients (three normal and three pathologic), suggests that such a spectroscopic marker, specific to aneurismal tissue characterization, could be important information for surgeons who face the dilemma of moderate aortic tissue dilatation of the ascending aortas.
journal_name
J Biophotonicsjournal_title
Journal of biophotonicsauthors
Bonnier F,Rubin S,Debelle L,Ventéo L,Pluot M,Baehrel B,Manfait M,Sockalingum GDdoi
10.1002/jbio.200810020subject
Has Abstractpub_date
2008-08-01 00:00:00pages
204-14issue
3eissn
1864-063Xissn
1864-0648journal_volume
1pub_type
杂志文章abstract::The research work presented in this paper focuses on qualitative tissue differentiation by monitoring the intensity ratios of atomic emissions using 'Laser Induced Breakdown Spectroscopy' (LIBS) on the plasma plume created during laser tissue ablation. The background of this study is to establish a real time feedback ...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201300159
更新日期:2015-01-01 00:00:00
abstract::The above article from the Journal of Biophotonics, published online on 9 January 2018 in Wiley Online Library as Early View (https://onlinelibrary.wiley.com/doi/abs/10.1002/jbio.201700354), and in Volume 11, e201700354, has been retracted by agreement between the authors (Hong Zhong, Lin Lu, Yuanhao Wang, Hongxing Ya...
journal_title:Journal of biophotonics
pub_type: 杂志文章,撤回出版物
doi:10.1002/jbio.201890133
更新日期:2020-04-01 00:00:00
abstract::Malaria is a life-threatening infectious blood disease affecting humans and other animals caused by parasitic protozoans belonging to the Plasmodium type especially in developing countries. The gold standard method for the detection of malaria is through the microscopic method of chemically treated blood smears. We de...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201700279
更新日期:2018-05-01 00:00:00
abstract::In biomedical applications, nanoparticles have demonstrated the potential to eradicate abnormal cells in small localized pathological zones associated with cancer or infections. Here, we introduce a method for nanotechnology-based photothermal (PT) killing of whole organisms considered harmful to humans or the environ...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201200199
更新日期:2014-07-01 00:00:00
abstract::A simple scheme for multimodal coherent anti-Stokes Raman scattering (CARS) microscopy is based on the spectral focusing of ultrafast-oscillator-derived pump/probe light and synchronous photonic crystal fiber (PCF) fiber-generated broadband Stokes light. To date, such schemes allowed rapid hyperspectral imaging throug...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201200171
更新日期:2014-01-01 00:00:00
abstract::Photobiomodulation (PBM) therapy has been noted to promote cell proliferation and growth in many different cell types shown both in vitro and in vivo. Currently, treatment regimens are used in the clinic for a variety of ailments, including wound healing. However, most protocols treat an anatomical site without consid...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201600025
更新日期:2016-12-01 00:00:00
abstract::223 Radium (223 Ra) is widely used in nuclear medicine to treat patients with osseous metastatic prostate cancer. In clinical practice 223 Ra cannot be imaged directly; however, gamma photons produced by its short-lived daughter nuclides can be captured by conventional gamma cameras. In this work, we show that 223 Ra ...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201700209
更新日期:2018-04-01 00:00:00
abstract::We report on transient membrane perforation of living cancer cells using plasmonic gold nanoparticles (AuNPs) enhanced single near infrared (NIR) femtosecond (fs) laser pulse. Under optimized laser energy fluence, single pulse treatment (τ = 45 fs, λ = 800 nm) resulted in 77% cell perforation efficiency and 90% cell v...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201500135
更新日期:2016-01-01 00:00:00
abstract::Cardiomyocytes derived from human pluripotent stem cells are a promising tool for disease modeling, drug compound testing, and cardiac toxicity screening. Bio-image segmentation is a prerequisite step in cardiomyocyte image analysis by digital holography (DH) in microscopic configuration and has provided satisfactory ...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201800116
更新日期:2018-12-01 00:00:00
abstract::The content of dermal beta-carotene can be a good indicator showing the body health. Because, it is involved in production of vitamin A maintaining healthy skin and mucous membranes. Also, it reduces the risk of cardiovascular diseases and its antioxidant capacity prevents the formation of cancerous cells. In this wor...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.202000124
更新日期:2020-09-01 00:00:00
abstract::The purpose of this study was to evaluate thermal and near-infrared (NIR) reflectance imaging methods for the assessment of the activity of root caries lesions. In addition, changes in the lesion structure were monitored with polarization sensitive optical coherence tomography (PS-OCT). Artificial bovine and natural r...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201500333
更新日期:2017-03-01 00:00:00
abstract::Nanofluidics enables the imaging of stretched single molecules with potential applications for single molecule sequence mapping. Lab-on-a-chip devices for single cell trapping and lyzing, genomic DNA extraction from single cells, and optical mapping of genomic length DNA has been demonstrated separately. Yet the pursu...
journal_title:Journal of biophotonics
pub_type: 杂志文章,评审
doi:10.1002/jbio.201200050
更新日期:2012-08-01 00:00:00
abstract::Perfusion and oxygenation are critical parameters of muscle metabolism in health and disease. They have been both the target of many studies, in particular using near-infrared spectroscopy (NIRS). However, difficulties with quantifying NIRS signals have limited a wide dissemination of the method to the clinics. Our ai...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201960169
更新日期:2020-06-01 00:00:00
abstract::Basidiomycetes, that is, mushroom-type fungi, are known to produce pigments in response to environmental impacts. As antioxidants with a high level of unsaturation, these compounds can neutralize highly oxidative species. In the event of close contact with other microbes, the enzymatically controlled pigment productio...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201700369
更新日期:2018-06-01 00:00:00
abstract::We report a compact, cost-effective tuned amplifier for frequency-selective amplification of the modulated signal in heterodyne detected nonlinear optical microscopy. Our method improved the signal to noise ratio by an order of magnitude compared to conventional lock-in detection, as demonstrated through stimulated Ra...
journal_title:Journal of biophotonics
pub_type: 社论
doi:10.1002/jbio.201200005
更新日期:2012-10-01 00:00:00
abstract::Laser therapy, also known as Photobiomodulation (PBM) is indicated to reduce pain associated with different pathologies and applied using protocols that vary in wavelength, irradiance and fluence. Its mechanisms of action are still unclear and possibly able to directly impact on pain transmission, reducing nociceptor ...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201900043
更新日期:2019-10-01 00:00:00
abstract::We have investigated the ability of dual-frequency Coherent Antistokes Raman Scattering (D-CARS) micro-spectroscopy, based on femtosecond pulses (100 fs or 5 fs) spectrally focussed by glass dispersion, to distinguish the chemical composition of micron-sized lipid droplets consisting of different triglycerides types (...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201200197
更新日期:2014-01-01 00:00:00
abstract::Drowsy driving contributes to ~20% of all traffic accidents worldwide. Onsite monitoring the mental condition of a driver and forewarning may be a preventive solution to reduce occurrence of drowsiness and potential accidents. Functional near-infrared spectroscopy (fNIRS) has been successfully utilized in hemodynamics...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201800160
更新日期:2018-12-01 00:00:00
abstract::In preclinical researches, bioluminescence tomography (BLT) has widely been used for tumor imaging and monitoring, imaged-guided tumor therapy, and so forth. For these biological applications, both tumor spatial location and morphology analysis are the leading problems needed to be taken into account. However, most ex...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201960218
更新日期:2020-04-01 00:00:00
abstract::The authors have developed a tomographic diffractive microscope that combines microholography with illumination from an angular synthetic aperture. It images specimens relative to their complex index of refraction distribution (index and absorption) and permits imaging of unlabelled specimens, with high lateral resolu...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.200900094
更新日期:2010-07-01 00:00:00
abstract::Noninvasive body shaping is becoming a growing demand. The aim of this study was to investigate the efficacy and safety of the combined treatments of 1064 nm Nd:YAG and 2940 nm Er:YAG in noninvasive lipolysis and skin tightening. Ten females were enrolled, and all women's side of the waist or the lower part of the abd...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201900083
更新日期:2019-09-01 00:00:00
abstract::The aim of this study was to evaluate whether OCT topography of the Bowman's layer and artificial intelligence (AI) can result in better diagnosis of forme fruste (FFKC) and clinical keratoconus (KC). Normal (n = 221), FFKC (n = 72) and KC (n = 116) corneas were included. Some of the FFKC and KC patients had the fello...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201900126
更新日期:2019-10-01 00:00:00
abstract::Surface-enhanced Raman scattering (SERS) is highly sensitive and label-free analytical technique based on Raman spectroscopy aided by field-multiplying plasmonic nanostructures. We report the use of SERS measurements of patient urine in conjunction with biostatistical algorithms to assess the treatment response of pro...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.202000275
更新日期:2021-01-01 00:00:00
abstract::Monitoring living cells in real-time is important in order to unravel complex dynamic processes in life sciences. In particular the dynamics of initiation and progression of degenerative diseases is intensely studied. In atherosclerosis the thickening of arterial walls is related to high lipid levels in the blood stre...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201600279
更新日期:2017-09-01 00:00:00
abstract::The purpose of this study was to evaluate the tomographic features of postrefractive surgery eyes. This was a retrospective evaluation of clinical data. Three patients with post-LASIK (laser-assisted in situ keratomileusis) and two patients with post-SMILE (small incision lenticule extraction) ectasia were imaged with...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201800253
更新日期:2019-02-01 00:00:00
abstract::Dynamic follow-up of exogenous molecules permeation through the skin is one among many competing applications for confocal Raman microspectroscopy. Previous studies showed the feasibility of tracking actives through the skin; the next step should be recording in vivo kinetics. Thus, we conducted a study to evaluate th...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201300011
更新日期:2014-09-01 00:00:00
abstract::Skin fibrosis is a chronic debilitating feature of several skin diseases that lead to characteristic increases in dermal fibroblast proliferation and collagen deposition through upregulation in components of the transforming growth factor beta (TGF-B)/SMAD pathway. In contrast to ultraviolet phototherapy, high-fluence...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201800207
更新日期:2019-05-01 00:00:00
abstract::The class of PEGylated emulsifiers finds broad application in the pharmaceutical and cosmetic industry. We target on one of the categories of polyethylene glycol (PEG) alkyl ethers with different lipophilic and hydrophilic chain length and aim to examine their effects on the skin comprehensively. In this study, we emp...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.202000286
更新日期:2020-12-01 00:00:00
abstract::Optical coherence tomography (OCT) is a well-developed technology that utilizes near-infrared light to reconstruct three-dimensional images of biological tissues with micrometer resolution. Improvements of the imaging contrast of the OCT technique are able to further widen its extensive biomedical applications. In thi...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201600047
更新日期:2017-06-01 00:00:00
abstract::A multiple exposure laser speckle contrast imaging (MELSCI) setup for visualizing blood perfusion was developed using a field programmable gate array (FPGA), connected to a 1000 frames per second (fps) 1-megapixel camera sensor. Multiple exposure time images at 1, 2, 4, 8, 16, 32 and 64 milliseconds were calculated by...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201700069
更新日期:2018-02-01 00:00:00