Abstract:
:The association between early atherosclerosis (IMT) and Atherogenic index of plasma (AIP), a marker of atherogenicity (log triglycerides/HDL Cholesterol) was evaluated in a population-based cohort study in women, aged 30-69, living in the metropolitan area of Naples, Southern Italy (Progetto ATENA). Serum cholesterol, HDL-cholesterol, LDL-cholesterol, Triglyceride, Insulin, HOMA, Apo B, hs-CPR were measured in 390 menopausal women, as a part of 5.062 participants of the cohort. Women in the second and third tertile of AIP showed an increased common carotid intima-media thickness compared with those in the first tertile: II vs I tertile (O.R. = 2.24, p = 0.007), III vs I tertile (O.R. = 2.29, p = 0.005), adjusted for age and Systolic pressure or II vs I tertile (O.R. = 2.19, p = 0.014), III vs I tertile (O.R. = 2.13, p = 0.026), adjusted for age, Systolic pressure, Body mass index and Apo B. Women in the second and third tertile of AIP compared to those in the first tertile, showed an OR of 2.14 (p = 0.016) and 1.99 (p = 0.033) respectively, of having elevates level of IMT, adjusted for traditional cardiovascular risk factor (age, Systolic Pressure, BMI, LDL Cholesterol, Diabetes diagnosis). This finding shows that in this group of menopausal women increased IMT is associated with elevated AIP independently of age and different cardiovascular risk factors. These results are in line with the hypothesis that AIP may be an useful clinical tools to give additional information in the risk assessment for atherosclerotic disease, in particular in postmenopausal women.
journal_name
Acta Cardioljournal_title
Acta cardiologicaauthors
Gentile M,Iannuzzo G,Simeon V,Mattiello A,Rubba F,Panico C,Panico S,Rubba Pdoi
10.1080/00015385.2020.1858537subject
Has Abstractpub_date
2020-12-11 00:00:00pages
1-6eissn
0001-5385issn
1784-973Xpub_type
杂志文章abstract::Residual risk, which cannot be prevented by statins alone, must be controlled for inhibiting the onset of coronary events. Omega-3 polyunsaturated fatty acids (PUFAs) play an important role in controlling residual risk. The Japan eicosapentaenoic acid (EPA) Lipid Intervention Study demonstrated the inhibitory effect o...
journal_title:Acta cardiologica
pub_type: 杂志文章,评审
doi:10.1080/00015385.2017.1305174
更新日期:2017-06-01 00:00:00
abstract::A total of 10 cases of non-bacterial thrombotic endocarditis (NBTE) were found among 1640 adult patients, autopsied in a 24-year period. Eight out of 10 patients had an underlying malignant tumor, NBTE was more common in cancer patients than in patients without malignancy (1.25% vs 0.2%, P less than 0.05). Patients wi...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:The effects of cigarette smoking on the circadian rhythm of heart rate variability (HRV) are not known. METHODS:We studied the effects of cigarette smoking on the circadian rhythm of HRV in 24 smoking and 21 non-smoking healthy subjects. Twenty-four hour ambulatory electrocardiograms were recorded and time ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.55.5.2005757
更新日期:2000-10-01 00:00:00
abstract::Background: Since many years catheter ablation is widely used for the treatment of atrial fibrillation (AF), however, long-term follow-up data of ablation techniques are rare. This study presents a 10-year follow-up period in patients treated for paroxysmal AF (PAF) with point-by-point pulmonary vein isolation (PVI) u...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2020.1756087
更新日期:2020-05-01 00:00:00
abstract::Most decision-support systems in medicine have been developed in hospital environments, but only few are designed for being used by general practitioners. The present work aims to design an expert system for practitioners in chronic heart failure (CHF) treatment. It provides assistance in defining the therapy relying ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract:OBJECTIVE:The present study was undertaken to test the hypothesis that smoking induces peripheral endothelial dysfunction and altered function in central conduit arteries. METHODS:A total of 22 healthy volunteers (10 women and 12 men; mean age 25.3 +/- 5.8 years) were included. At baseline, brachial artery flowmediate...
journal_title:Acta cardiologica
pub_type: 杂志文章,随机对照试验
doi:10.1080/ac.68.3.2983419
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:The present study was designed to examine the changes of MMP-2/TIMP-2 in the hearts of streptozotocin-induced diabetic rats and gain insight into their roles in extracellular matrix (ECM) remodelling on an experimental animal model of diabetic cardiomyopathy. METHODS AND RESULTS:Sixteen male Wistar rats were...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.62.5.2023412
更新日期:2007-10-01 00:00:00
abstract:OBJECTIVE:Due to uncertainty in the clinical implications of slow coronary flow (SCF), we aimed to investigate the clinical features and mid-term outcome of the Iranian patients with the slow coronary flow phenomenon. METHODS:During a four-year period from January 2005 to December 2009, out of 3523 consecutive patient...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.67.5.2174134
更新日期:2012-10-01 00:00:00
abstract::A definitive diagnosis in patients with syncope is often problematic if the cause is not evident after initial clinical assessment. The cause of syncope may be not established due to the infrequent, episodic occurrence. A symptom-rhythm correlation is frequently an unattainable gold standard in many patients. The impl...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:The coronary slow flow phenomenon is an angiographic finding characterized by delayed distal vessel opacification in the absence of significant epicardial coronary disease, and is an important clinical entity because it may be the cause of angina at rest or during exercise, acute myocardial infarction, and h...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.63.5.2033224
更新日期:2008-10-01 00:00:00
abstract:OBJECTIVES:The purpose of this study is to determine plasma fibronectin level and its relationships with plasma lipids, lipoproteins and C-reactive protein (CRP) levels in patients with dyslipidaemia during lipid-lowering therapy. METHODS:Plasma levels of fibronectin, CRP, fibrinogen, lipids and lipoproteins in 38 pat...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.57.6.2005466
更新日期:2002-12-01 00:00:00
abstract:OBJECTIVE:The aortic distensibility index, as a measure of vascular function, can serve as a marker of coronary artery disease severity. This study explores the feasibility of using the non-invasively measured index as an indicator of severity of coronary stenosis. METHODS:One hundred patients with normal left ventric...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.70.4.3096895
更新日期:2015-08-01 00:00:00
abstract::Left ventricular-right atrial communication is a relatively rare surgically corrigible congenital heart defect. We report a case with review of the literature. ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract:OBJECTIVE:This study evaluated autonomic nervous system function in 5 young (6-10 years old) and 5 older (10-15 years) children with recurrent episodes of neurally mediated syncope and a positive tilt-test result, 10 with syncope but a negative test result and 30 age-matched healthy volunteers. METHODS:Time- (SDNN, SD...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.55.3.2005734
更新日期:2000-06-01 00:00:00
abstract::In order to define the role of the ubiquitin-proteasome system in atherosclerotic plaque rupture in patients with type 2 diabetes mellitus (T2DM), we evaluated the amount of this system, of the main inflammatory cells, of the collagen content and some indexes indicative of oxidative stress in the carotid plaques of bo...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.61.6.2017962
更新日期:2006-12-01 00:00:00
abstract:OBJECTIVE:Decreased effects of smoking on serum high-density lipoprotein cholesterol (HDL-c) were demonstrated in subjects smoking more than 20 cigarettes a day. We aimed to evaluate the effects of non-heavy smoking (< or =20 cigarettes a day) on HDL-c in young, healthy men who are similar in terms of age, physical act...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.61.4.2017301
更新日期:2006-08-01 00:00:00
abstract:OBJECTIVE:This study investigates the relationship between post-heparin plasma lipoprotein lipase (LPL) activity, chronic inflammation and premature stable coronary artery disease (CAD) in male patients. METHODS AND RESULTS:132 male patients (< 55 years) with documented stable CAD (cases) and 130 male subjects without...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.64.3.2038025
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVE:dobutamine stress echocardiography (DSE) in patients with ischaemic cardiomyopathy. We explored the accuracy of resting echocardiographic and tissue Doppler parameters to predict a positive response by low-dose METHODS AND RESULTS:We enrolled 100 consecutive patients with prior myocardial infarction, and a l...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.67.6.2184672
更新日期:2012-12-01 00:00:00
abstract::Color-coded liquid plastic was injected intraparenchymally (not into the blood vessels) into more than 300 hearts of homeotherms--including dog, cat, sheep, beef, horse, mammalian dolphins, chickens, turkeys, etc. The organization of the hearts of all these species appears to be similar. After injection of a heart seg...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::The present study was designated to assess long term functional capacity, blood pressure and renal function at 12 and 60 months after heart transplantation. The data of sixty heart transplant recipients were retrospectively reviewed. At rest, radionuclide ejection fraction and cardiac index measured by thermodilution ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract:OBJECTIVE:A prospective randomized multicentre pilot trial, comparing stenting with balloon angioplasty as a treatment for coronary lesions, located in a bifurcation was performed. METHODS AND RESULTS:After balloon dilatation, with a < 30% residual stenosis in the main vessel and < 50% residual stenosis in the side br...
journal_title:Acta cardiologica
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.2143/AC.60.4.2004986
更新日期:2005-08-01 00:00:00
abstract::Thromboembolic events are major causes of morbidity and mortality in patients with native heart valve disease and artificial heart valves. Oral anticoagulation can reduce these complications. The indication for and intensity of oral anticoagulation depends on both, the risk for thromboembolic events and the risk of he...
journal_title:Acta cardiologica
pub_type: 杂志文章,评审
doi:
更新日期:1996-01-01 00:00:00
abstract::Background: The objective was to explore the value of serum carbohydrate antigen 125 (CA125) combined with N-terminal pro B-type natriuretic peptide (NT-proBNP) in predicting the clinical prognosis of patients with acute heart failure (AHF).Methods: We prospectively observed 213 patients with AHF. CA125 (U/ml) and NT-...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2020.1769347
更新日期:2020-06-10 00:00:00
abstract::Experimental demonstration that the external phonocardiogram is similar to the third derivative (rate of acceleration) of LV pressure, and that catecholamines cause a similar increase of the early systolic wave of the first derivative of LV pressure and of S1 prompted a study of the first sound during stress testing. ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract::We present two cases of Ortner's syndrome, a syndrome with hoarseness caused by unilateral left recurrent laryngeal nerve palsy as a complication of cardiovascular diseases. In the first case, aneurysmatic dilatation of the aorta and in the second case a dilated pulmonary trunk was thought to be the cause. ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.65.6.2059871
更新日期:2010-12-01 00:00:00
abstract::In eighteen consecutive patients (14 male, 4 females, in the age 37-52 years, mean = 43 years) with dilated cardiomyopathy in NYHA functional classification groups III-IV, the efficacy of ambulatory long-term (mean = 6 years) vasodilator therapy by means mechanocardiography (systolic and diastolic time intervals) and ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::A clinical, electrocardiographic and coronarographic study of ten cases shows that surelevation of ST-segment during exercise (without any signs of infarction) correspond to very different clinical situations of anatomical state of coronary vessels, occurrence of coronary spasm and evolution of the ischemic disease. "...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1977-01-01 00:00:00
abstract::We report the case of a 61-year-old male patient who suffered a spontaneous (atraumatic) splenic rupture (SSR) following splenic infarction treated by heparin anticoagulation. Splenic rupture precipitated by thrombolytic or anticoagulant therapy has been reported and putatively attributed to unrecognized micro-traumat...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.68.4.2988897
更新日期:2013-08-01 00:00:00
abstract::A follow-up study was carried out in 98 patients with congestive cardiomyopathy using clinical data and M-mode echocardiography. 59 patients survived (mean follow-up period 18 months), 39 patients died (mean survival period 12.6 months). Median survival time was 3 years. Prognosis was unfavorably affected by ECG signs...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract::Background: All previous meta-analyses including clinical outcomes after remote ischaemic conditioning (RIC) in patients with ST-elevation myocardial infarction (STEMI) treated with percutaneous coronary intervention (PCI) demonstrated that RIC significantly reduced all-cause mortality and major adverse cardiovascular...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2020.1766259
更新日期:2020-07-03 00:00:00