当前位置： SCI文献检索 > JOURNAL OF CRITICAL CARE期刊下所有文献 > COVID-19 and non-COVID ARDS patients demonstrate a distinct response to low dose steroids- A retrospective observational study.

COVID-19 and non-COVID ARDS patients demonstrate a distinct response to low dose steroids- A retrospective observational study.

Abstract：

:Patients with COVID-19 ARDS have distinct physiological and immunological phenotypes compared to patients with non-COVID ARDS. Patients with COVID-19 ARDS (n = 32) had a significant improvement in PaO2: FiO2 ratio (p = 0.046) following low-dose steroid treatment, unlike patients with non-COVID ARDS (n = 16) (p = 0.529). Patients with COVID-19 ARDS had a greater fall in CRP compared to patients with non-COVID ARDS, albeit not statistically significant (p = 0.07). Our novel findings highlight differences in the underlying physiological and immunological phenotypes between COVID-19 and non-COVID ARDS, with implications for future ARDS studies.

journal_name

J Crit Care

journal_title

Journal of critical care

authors

Longobardo A,Snow TAC,Montanari C,Shulman R,Singer M,Arulkumaran N

doi

10.1016/j.jcrc.2020.11.012

subject

Has Abstract

pub_date

2020-11-21 00:00:00

pages

46-48

eissn

0883-9441

issn

1557-8615

pii

S0883-9441(20)30773-5

journal_volume

62

pub_type

杂志文章

相关文献

JOURNAL OF CRITICAL CARE文献大全
  • Ketamine for analgosedation in critically ill patients.

    abstract：PURPOSE:The purpose of this narrative review is to provide practical and useful guidance for clinicians considering the use of intravenous ketamine for its analgosedative properties in adult, critically ill patients. METHODS:MEDLINE was searched from inception until January 2016. Articles related to the pharmacologica...

    journal_title：Journal of critical care

    pub_type： 杂志文章,评审

    doi：10.1016/j.jcrc.2016.05.016

    authors： Erstad BL,Patanwala AE

    更新日期：2016-10-01 00:00:00

  • Dysbiosis in the intensive care unit: Microbiome science coming to the bedside.

    abstract：:Complex microbial communities within the human body, constituting the microbiome, have a broad impact on human health and disease. A growing body of research now examines the role of the microbiome in patients with critical illness, such as sepsis and acute respiratory failure. In this article, we provide an introduct...

    journal_title：Journal of critical care

    pub_type： 杂志文章,评审

    doi：10.1016/j.jcrc.2016.09.029

    authors： Kitsios GD,Morowitz MJ,Dickson RP,Huffnagle GB,McVerry BJ,Morris A

    更新日期：2017-04-01 00:00:00

  • Prognostic nomogram for acute pancreatitis patients: An analysis of publicly electronic healthcare records in intensive care unit.

    abstract：PURPOSE:The mortality rate of severe acute pancreatitis (AP) is 20-30% even after admission to intensive care unit (ICU). Thus we aimed to develop a laboratory-based nomogram to identify AP patients at high risk for mortality. MATERIALS AND METHODS:The primary and validation cohorts were extracted from the Medical Inf...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2018.10.030

    authors： Jiang X,Su Z,Wang Y,Deng Y,Zhao W,Jiang K,Sun C

    更新日期：2019-04-01 00:00:00

  • Comprehensive evidence-based clinical practice guidelines for ventilator-associated pneumonia: prevention.

    abstract：BACKGROUND:Ventilator-associated pneumonia (VAP) is an important cause of morbidity and mortality in ventilated critically ill patients. PURPOSE:To develop evidence-based guidelines for the prevention of VAP. DATA SOURCES:MEDLINE, EMBASE, CINAHL, and the Cochrane Database of Systematic Reviews and Register of Control...

    journal_title：Journal of critical care

    pub_type： 杂志文章,实务指引

    doi：10.1016/j.jcrc.2007.11.014

    authors： Muscedere J,Dodek P,Keenan S,Fowler R,Cook D,Heyland D,VAP Guidelines Committee and the Canadian Critical Care Trials Group.

    更新日期：2008-03-01 00:00:00

  • Persistent sepsis-induced hypotension without hyperlactatemia: is it really septic shock?

    abstract：PURPOSE:The prognostic value of hyperlactatemia in septic shock is unquestionable. However, as current definitions do not include hyperlactatemia as a mandatory criterion, some hypotensive patients may be diagnosed as having septic shock despite exhibiting normolactatemia. The significance of persistent sepsis-induced ...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2010.09.007

    authors： Hernandez G,Castro R,Romero C,de la Hoz C,Angulo D,Aranguiz I,Larrondo J,Bujes A,Bruhn A

    更新日期：2011-08-01 00:00:00

  • Impact of endotracheal intubation on septic shock outcome: A post hoc analysis of the SEPSISPAM trial.

    abstract：INTRODUCTION:The objective of the study to is to determine the characteristics associated with endotracheal intubation in septic shock patients. METHODS:This is a post hoc analysis of the database of the SEPSISPAM study, including patients with septic shock. RESULTS:Among the 776 patients, 633 (82%) were intubated wi...

    journal_title：Journal of critical care

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.jcrc.2015.08.018

    authors： Delbove A,Darreau C,Hamel JF,Asfar P,Lerolle N

    更新日期：2015-12-01 00:00:00

  • Comparison of 3 modes of automated weaning from mechanical ventilation: a bench study.

    abstract：PURPOSE:Automated weaning modes are available in some mechanical ventilators, but no studies compared them hitherto. We compared the performance of 3 automated modes under standard and challenging situations. METHODS:We used a lung simulator to compare 3 automated modes, adaptive support ventilation (ASV), mandatory r...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2011.12.021

    authors： Morato JB,Sakuma MT,Ferreira JC,Caruso P

    更新日期：2012-12-01 00:00:00

  • High central venous pressure is associated with acute kidney injury and mortality in patients underwent cardiopulmonary bypass surgery.

    abstract：PURPOSE:We sought to investigate the relationship between high CVP, AKI, and mortality in patients undergoing cardiac surgery with cardiopulmonary bypass. MATERIALS:All patients aged 18 years or older who underwent cardiac surgery with CPB were prospectively reviewed. Patients were excluded when renal artery were invo...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2018.08.034

    authors： Yang Y,Ma J,Zhao L

    更新日期：2018-12-01 00:00:00

  • Development and implementation of an early mobility program for mechanically ventilated pediatric patients.

    abstract：PURPOSE:Early mobility (EM) is being used in adult ICUs in an effort to treat and prevent intensive care unit acquired weakness (ICU-AW) and Post-Intensive Care Syndrome (PICS). Data supports children suffer from ICU-AW and PICS as well. Our objective was to create and implement an EM protocol for pediatric patients re...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2017.08.004

    authors： Betters KA,Hebbar KB,Farthing D,Griego B,Easley T,Turman H,Perrino L,Sparacino S,deAlmeida ML

    更新日期：2017-10-01 00:00:00

  • Development and validation of a novel fusion algorithm for continuous, accurate, and automated R-wave detection and calculation of signal-derived metrics.

    abstract：PURPOSE:Previous studies have shown that heart rate complexity may be a useful indicator of patient status in the critical care environment but will require continuous, accurate, and automated R-wave detection (RWD) in the electrocardiogram (ECG). Although numerous RWD algorithms exist, accurate detection remains a cha...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2013.02.015

    authors： Liu NT,Batchinsky AI,Cancio LC,Baker WL Jr,Salinas J

    更新日期：2013-10-01 00:00:00

  • Association of tumor necrosis factor α -308G/A and interleukin-6 -174G/C gene polymorphism with pneumonia-induced sepsis.

    abstract：PURPOSE:Sepsis is a lethal outcome of the inflammation and coagulation process. Human interleukin (IL)-6 and tumor necrosis factor (TNF) α are well-known inflammation factors closely associated with sepsis. In the present study, we aim to investigate the association of promoter-region polymorphisms IL-6 (-174G/C) rs180...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2015.04.123

    authors： Feng B,Mao ZR,Pang K,Zhang SL,Li L

    更新日期：2015-10-01 00:00:00

  • Selective digestive decontamination in critically ill children: A survey of Canadian providers.

    abstract：BACKGROUND:Selective digestive decontamination of the digestive tract involves the routine administration of oral, gastric, and intravenous antibiotics to mechanically ventilated children to prevent hospital-acquired infections. It has a strong evidence base in adults, with limited pediatric evidence. Current utilizati...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2017.02.024

    authors： Murthy S,Pathan N,Cuthbertson BH

    更新日期：2017-06-01 00:00:00

  • Fluid resuscitation mediates the association between inhalational burn injury and acute kidney injury in the major burn population.

    abstract：BACKGROUND:It is known that acute respiratory distress syndrome and acute lung injury are independent risk factors for developing acute kidney injury (AKI) through complex pathophysiologic mechanisms. Our specific aim is to evaluate the risk factors for AKI postburn injury and whether inhalation thermal injury is an in...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2016.10.008

    authors： Kumar AB,Andrews W,Shi Y,Shotwell MS,Dennis S,Wanderer J,Summitt B

    更新日期：2017-04-01 00:00:00

  • Effect of alpha-adrenoreceptor stimulation on the diaphragmatic oxygen delivery-consumption relationship.

    abstract：PURPOSE:In the vascularly isolated canine hemidiaphragm, we tested the hypothesis that alpha-adrenoreceptor stimulation may influence diaphragmatic function and O2 extraction during reductions in O2 delivery (QO2di). METHODS:The diaphragm was perfused using a constant flow pump with blood diverted from the left femora...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/s0883-9441(96)90016-7

    authors： Ward ME,Hussain SN

    更新日期：1996-03-01 00:00:00

  • Sepsis and organ system failure are major determinants of post-intensive care unit mortality.

    abstract：PURPOSE:The aim of the study was to investigate predictors of post-intensive care unit (ICU) in-hospital mortality with special emphasis on the impact of sepsis and organ system failure. METHODS:This study is a subanalysis of the database from the observational Sepsis Occurrence in Acutely Ill Patients study conducted...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2007.09.006

    authors： Sakr Y,Vincent JL,Ruokonen E,Pizzamiglio M,Installe E,Reinhart K,Moreno R,Sepsis Occurrence in Acutely Ill Patients Investigators.

    更新日期：2008-12-01 00:00:00

  • Relation of heart rate variability to serum levels of C-reactive protein, interleukin 6, and 10 in patients with sepsis and septic shock.

    abstract：PURPOSE:The aim of the study was to investigate possible associations between different heart rate variability (HRV) indices and various biomarkers of inflammation in 45 septic patients. MATERIALS AND METHODS:We daily assessed HRV in the time domain (SD of RR intervals [SDNN]), frequency domain (low [LF], high frequen...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2008.11.010

    authors： Papaioannou VE,Dragoumanis C,Theodorou V,Gargaretas C,Pneumatikos I

    更新日期：2009-12-01 00:00:00

  • Healthcare-associated ventriculitis and meningitis in a neuro-ICU: Incidence and risk factors selected by machine learning approach.

    abstract：PURPOSE:To define the incidence of healthcare-associated ventriculitis and meningitis (HAVM) in the neuro-ICU and to identify HAVM risk factors using tree-based machine learning (ML) algorithms. METHODS:An observational cohort study was conducted in Russia from 2010 to 2017, and included high-risk neuro-ICU patients. ...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2018.01.022

    authors： Savin I,Ershova K,Kurdyumova N,Ershova O,Khomenko O,Danilov G,Shifrin M,Zelman V

    更新日期：2018-06-01 00:00:00

  • Critically ill cancer patient in intensive care unit: issues that arise.

    abstract：:Advances in the management of malignancies and organ failures have led to substantial increases in survival as well as in the number of cancer patients requiring intensive care unit (ICU) admission. Although effectiveness of ICU in this group remains controversial, the heterogeneity of its population in terms of the n...

    journal_title：Journal of critical care

    pub_type： 杂志文章,评审

    doi：10.1016/j.jcrc.2014.04.007

    authors： Kostakou E,Rovina N,Kyriakopoulou M,Koulouris NG,Koutsoukou A

    更新日期：2014-10-01 00:00:00

  • Predictors for mortality after prolonged mechanical ventilation after cardiac surgery in children.

    abstract：PURPOSE:To identify early mortality-associated clinical risk factors preceding, during, and after cardiac surgery in children. MATERIALS AND METHODS:Of the 722 children admitted to our pediatric intensive care unit (PICU) from January 1992 to January 1997 after repair of congenital heart defects, 70 required 48 hours ...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1053/jcrc.2002.36760

    authors： Ben-Abraham R,Efrati O,Mishali D,Yulia F,Vardi A,Barzilay Z,Paret G

    更新日期：2002-12-01 00:00:00

  • Clinical course after identification of new-onset atrial fibrillation in critically ill patients: The AFTER-ICU study.

    abstract：PURPOSE:Epidemiological information is lacking after identification of new-onset atrial fibrillation (AF) in critically ill patients. This study aimed to describe the clinical course after the identification of new-onset AF. MATERIALS AND METHODS:This prospective cohort study enrolled adult patients with new-onset AF ...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2020.06.014

    authors： Yoshida T,Uchino S,Sasabuchi Y,AFTER-ICU study group.

    更新日期：2020-10-01 00:00:00

  • Diarrhea and patient outcomes in the intensive care unit: Systematic review and meta-analysis.

    abstract：PURPOSE:We aimed to determine whether diarrhea experienced by patients in the intensive care unit (ICU) is related to their clinical outcomes. MATERIAL AND METHODS:We performed a systematic review and meta-analysis. We searched the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE, CINAHL, and the World ...

    journal_title：Journal of critical care

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.jcrc.2019.06.014

    authors： Taito S,Kawai Y,Liu K,Ariie T,Tsujimoto Y,Banno M,Kataoka Y

    更新日期：2019-10-01 00:00:00

  • Validity of a clinical scale in predicting the failure of non-invasive ventilation in hypoxemic patients.

    abstract：INTRODUCTION:The HACOR scale is a clinical score that can predict early failure of NIV in hypoxemic acute respiratory failure (ARF) The aim of this study is to analyze the validity of the HACOR scale. METHODS:A retrospective study of a cohort of over 2749 episodes on 2711 consecutive patients requiring NIV for hypoxem...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2020.08.008

    authors： Carrillo A,Lopez A,Carrillo L,Caldeira V,Guia M,Alonso N,Renedo A,Quintana ME,Sanchez JM,Esquinas A

    更新日期：2020-12-01 00:00:00

  • Comparison of traditional microbiological culture and 16S polymerase chain reaction analyses for identification of preoperative airway colonization for patients undergoing lung resection.

    abstract：PURPOSE:Preoperative airway colonization is associated with increased risk of postoperative respiratory complications following lung resection. This study compares the rates of preoperative lower respiratory tract colonization identified by traditional culture and novel 16S polymerase chain reaction (PCR) tests. MATER...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2018.04.013

    authors： Howitt SH,Blackshaw D,Fontaine E,Hassan I,Malagon I

    更新日期：2018-08-01 00:00:00

  • A modified Delphi process to identify clinical and research priorities in patient and family centred critical care.

    abstract：PURPOSE:To identify elements which enable patient and family centred care (PFCC) in the intensive care unit (ICU) and priorities for PFCC research. MATERIALS AND METHODS:We engaged a panel of multidisciplinary stakeholders in a modified Delphi process. Items generated from a literature review and panelist suggestions ...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2017.08.008

    authors： Oczkowski SJW,Au S,des Ordons AR,Gill M,Potestio ML,Smith O,Sinuff T,Stelfox HT,Fox-Robichaud AE

    更新日期：2017-12-01 00:00:00

  • A survey of clinicians addressing the approach to the management of severe sepsis and septic shock in the United States.

    abstract：PURPOSE:Mortality in severe sepsis and septic shock (SS/SS) remains high. Surviving Sepsis Campaign (SSC) guidelines were published in 2004 with the goal of improving outcomes in SS/SS. We tested the hypothesis that adherence to SSC guidelines and management of patients with SS/SS were influenced by physician specialty...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2010.04.005

    authors： Djurkovic S,Baracaldo JC,Guerra JA,Sartorius J,Haupt MT

    更新日期：2010-12-01 00:00:00

  • The effects of transjugular intrahepatic portosystemic stent shunt on systemic cardiocirculatory parameters.

    abstract：PURPOSE:We aimed to evaluate the effects of transjugular intrahepatic portosystemic stent shunt (TIPS) on systemic cardiocirculatory parameters in patients treated with TIPS for portal hypertension-associated complications. MATERIALS AND METHODS:This prospective study was conducted in an intensive care unit of a Germa...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2014.06.028

    authors： Saugel B,Mair S,Meidert AS,Phillip V,Messer M,Nennstiel S,Berger H,Gaa J,Wagner JY,Schneider H,Schmid RM,Huber W

    更新日期：2014-12-01 00:00:00

  • Failure to reduce C-reactive protein levels more than 25% in the last 24 hours before intensive care unit discharge predicts higher in-hospital mortality: a cohort study.

    abstract：PURPOSE:To discharge a patient from the intensive care unit (ICU) is a complex decision-making process because in-hospital mortality after critical illness may be as high as up to 27%. Static C-reactive protein (CRP) values have been previously evaluated as a predictor of post-ICU mortality with conflicting results. Th...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2011.10.013

    authors： Ranzani OT,Prada LF,Zampieri FG,Battaini LC,Pinaffi JV,Setogute YC,Salluh JI,Povoa P,Forte DN,Azevedo LC,Park M

    更新日期：2012-10-01 00:00:00

  • Predictors of extraventricular drain-associated bacterial ventriculitis.

    abstract：PURPOSE:Bacterial ventriculitis (BV) may develop in patients requiring external ventricular drains (EVDs). The purpose of this study was to determine predictors of EVD-associated BV onset. MATERIALS AND METHODS:A retrospective review of Duke University Hospital patients with EVD device placement between January 2005 a...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2013.08.012

    authors： Williamson RA,Phillips-Bute BG,McDonagh DL,Gray MC,Zomorodi AR,Olson DM,Britz GW,Laskowitz DT,James ML

    更新日期：2014-02-01 00:00:00

  • Variation in mortality rates after admission to long-term acute care hospitals for ventilator weaning.

    abstract：PURPOSE:We sought to examine variation in long-term acute care hospital (LTACH) quality based on 90-day in-hospital mortality for patients admitted for weaning from mechanical ventilation. METHODS:We developed an administrative risk-adjustment model using data from Medicare claims. We validated the administrative mode...

    journal_title：Journal of critical care

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.jcrc.2018.03.022

    authors： Kahn JM,Davis BS,Le TQ,Yabes JG,Chang CH,Angus DC

    更新日期：2018-08-01 00:00:00

  • Mean arterial pressure and mean perfusion pressure deficit in septic acute kidney injury.

    abstract：BACKGROUND:Changes in mean perfusion pressure (MPP) from premorbid resting values may contribute to the progression of septic acute kidney injury (AKI). OBJECTIVES:In patients with septic shock, we aimed to investigate the association of changes from premorbid values with AKI severity and progression. METHODS:We obta...

    journal_title：Journal of critical care

    pub_type： 杂志文章

    doi：10.1016/j.jcrc.2015.05.003

    authors： Wong BT,Chan MJ,Glassford NJ,Mårtensson J,Bion V,Chai SY,Oughton C,Tsuji IY,Candal CL,Bellomo R

    更新日期：2015-10-01 00:00:00