Abstract:
OBJECTIVE:To investigate the diagnostic performance of contrast-enhanced ultrasound (CEUS) and its role as a second-line imaging modality after gadoxetate-enhanced MRI (Gd-EOB-MRI) in the diagnosis of hepatocellular carcinoma (HCC) among at risk observations. MATERIALS AND METHODS:We prospectively enrolled participants at risk of HCC with treatment-naïve solid hepatic observations (≥ 1 cm) of Liver Imaging Reporting and Data System (LR)-3/4/5/M during surveillance and performed Gd-EOB-MRI. A total of one hundred and three participants with 103 hepatic observations (mean size, 28.2 ± 24.5 mm; HCCs [n = 79], non-HCC malignancies [n = 15], benign [n = 9]; diagnosed by pathology [n = 57], or noninvasive method [n = 46]) were included in this study. The participants underwent CEUS with sulfur hexafluoride. Arterial phase hyperenhancement (APHE) and washout on Gd-EOB-MRI and CEUS were evaluated. The distinctive washout in CEUS was defined as mild washout 60 seconds after contrast injection. The diagnostic ability of Gd-EOB-MRI and of CEUS as a second-line modality for HCC were determined according to the European Association for the Study of the Liver (EASL) and the Korean Liver Cancer Association and National Cancer Center (KLCA-NCC) guidelines. The diagnostic abilities of both imaging modalities were compared using the McNemar's test. RESULTS:The sensitivity of CEUS (60.8%) was lower than that of Gd-EOB-MRI (72.2%, p = 0.06 by EASL; 86.1%, p < 0.01 by KLCA-NCC); however, the specificity was 100%. By performing CEUS on the inconclusive observations in Gd-EOB-MRI, HCCs without APHE (n = 10) or washout (n = 12) on Gd-EOB-MRI further presented APHE (80.0%, 8/10) or distinctive washout (66.7%, 8/12) on CEUS, and more HCCs were diagnosed than with Gd-EOB-MRI alone (sensitivity: 72.2% vs. 83.5% by EASL, p < 0.01; 86.1% vs. 91.1% by KCLA-NCC, p = 0.04). There were no false-positive cases for HCC on CEUS. CONCLUSION:The addition of CEUS to Gd-EOB-MRI as a second-line diagnostic modality increases the frequency of HCC diagnosis without changing the specificities.
journal_name
Korean J Radioljournal_title
Korean journal of radiologyauthors
Kang HJ,Lee JM,Yoon JH,Han JKdoi
10.3348/kjr.2020.0973subject
Has Abstractpub_date
2020-11-03 00:00:00eissn
1229-6929issn
2005-8330pii
21.e172pub_type
杂志文章abstract:OBJECTIVE:To assess the feasibility of T2*-corrected fat-signal fraction (FF) map by using the three-echo volume interpolated breath-hold gradient echo (VIBE) Dixon sequence to differentiate between malignant marrow-replacing lesions and benign red marrow deposition of vertebrae. MATERIALS AND METHODS:We assessed 32 l...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2014.15.6.781
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:Concurrent low brain and high liver uptake are sometimes observed on fluorine-18-labeled fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET). We investigated the potential clinical significance of this uptake pattern related to metabolic syndrome (MS). MATERIALS AND METHODS:We retrospectively r...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2017.18.2.392
更新日期:2017-03-01 00:00:00
abstract:OBJECTIVE:To retrospectively evaluate the frequency and risk factors for developing thrombus in a systemic vein such as the infrarenal inferior vena cava or the iliac vein, in which a balloon-occluded retrograde transvenous obliteration (B-RTO) catheter was indwelled. MATERIALS AND METHODS:Forty-nine patients who unde...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2012.13.3.324
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:We investigated low dose digital tomosynthesis (DT) for the evaluation of the paranasal sinus (PNS), and compared its diagnostic accuracy with a PNS radiography series (XR). MATERIALS AND METHODS:We enrolled 43 patients for whom XR, PNS DT, and OMU CT were performed. We measured effective doses (EDs) of XR, ...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2012.13.2.136
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVE:We wanted to present our experiences for performing transradial cerebral angiography during the learning period, and we also wanted to demonstrate this procedure's technical feasibility and utility in various clinical situations. MATERIALS AND METHODS:Thirty-two patients were enrolled in the study. All of th...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2006.7.1.7
更新日期:2006-01-01 00:00:00
abstract::A narrow internal auditory canal (IAC) with duplication is a rare anomaly of the temporal bone. It is associated with congenital sensorineural hearing loss. Aplasia or hypoplasia of the vestibulocochlear nerve may cause the hearing loss. We present an unusual case of an isolated narrow IAC with duplication that was de...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2008.9.s.s22
更新日期:2008-07-01 00:00:00
abstract::A 64-year-old male patient with liver cirrhosis underwent a CT study for hepatocellular carcinoma surveillance, which demonstrated a 1.4-cm hypervascular subcapsular tumor in the liver. On gadoxetic acid-enhanced MRI, the tumor showed brisk arterial enhancement and persistent hyperenhancement in the portal phase, but ...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2013.14.5.769
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVE:To evaluate spine magnetic resonance imaging (MRI) inter-reader and intra-reader reliabilities using the thoracolumbar injury classification system and severity score (TLICS) and to analyze the effects of reader experience on reliability and the possible reasons for discordant interpretations. MATERIALS AND ...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2015.16.4.889
更新日期:2015-07-01 00:00:00
abstract:OBJECTIVE:To determine the safety and usefulness of a two-tiered approach to balloon-occluded retrograde transvenous obliteration (B-RTO) as a treatment for large gastric varices after portal hypertension. MATERIALS AND METHODS:50 patients were studied who underwent B-RTO for gastric varices between October 2004 and O...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2013.14.3.439
更新日期:2013-05-01 00:00:00
abstract::Primary lymphoma of the uterus is a rare disease, the reported characteristic MR imaging findings being homogeneous intermediate signal intensity of the indistinct mass on T1- and T2-weighted images, and the preservation of endometrial lining and uterine architecture. We report a case of primary uterine lymphoma which...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2000.1.4.223
更新日期:2000-10-01 00:00:00
abstract:OBJECTIVE:We wanted to assess the MR imaging findings of ovarian cystadenofibroma and cystadenocarcinofibroma, and we wanted to find clues for making the differential diagnosis between them. MATERIALS AND METHODS:The MR images of 12 pathologically proven cystadenofibromas and two cystadenocarcinofibromas were reviewed...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2006.7.3.199
更新日期:2006-07-01 00:00:00
abstract::We describe here a case of intraductal tubular carcinoma of the main pancreatic duct. Gadolinium-enhanced pancreas magnetic resonance (MR) imaging showed an enhancing mass that was confined in the dilated main pancreatic duct of the pancreatic body, along with dilatation of the upstream main pancreatic duct and chroni...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2008.9.5.473
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:The purpose of the current study was to develop support vector machine (SVM) and artificial neural network (ANN) models for the pre-operative prediction of advanced prostate cancer by using the parameters acquired from transrectal ultrasound (TRUS)-guided prostate biopsies, and to compare the accuracies betwe...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2011.12.5.588
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to develop a new method for automated lung nodule detection in serial section CT images with using the characteristics of the 3D appearance of the nodules that distinguish themselves from the vessels. MATERIALS AND METHODS:Lung nodules were detected in four steps. First, to redu...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2008.9.1.1
更新日期:2008-01-01 00:00:00
abstract:Objective:To evaluate the current status of managing adverse reactions to iodinated contrast media (ICM) for computed tomography in referral hospitals in South Korea compared with hospitals in other countries. Materials and Methods:This survey investigation involved 59 Korean and 15 overseas hospitals using guideline-...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2017.0771
更新日期:2019-01-01 00:00:00
abstract::In order to relieve mechanical obstruction caused by rectal carcinoma, a bare rectal stent was inserted in the sigmoid colon of a 70-year-old female. The procedure was successful, and for one month the patient made good progress. She then complained of abdominal pain, however, and plain radiographs of the chest and ab...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2000.1.3.169
更新日期:2000-07-01 00:00:00
abstract:OBJECTIVE:We wanted to introduce a new technique for superselective catheterization of arteries with preshaping of a micro-guide wire into a shepherd's hook form, and this is useful for superselection of small arteries branching at an acute angle from a large parent artery for the treatment of tumors and hemorrhages. ...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2007.8.3.225
更新日期:2007-05-01 00:00:00
abstract:OBJECTIVE:We wanted to evaluate the image quality, diagnostic accuracy and radiation exposure of 64-slice dual-source CT (DSCT) coronary angiography according to the heart rate in symptomatic patients during daily clinical practice. MATERIALS AND METHODS:We performed a retrospective search for the DSCT coronary angiog...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2011.12.3.308
更新日期:2011-05-01 00:00:00
abstract::In stenosis of a segmental branch or among multiple renal arteries, Doppler sampling of intrarenal arteries in the upper, mid and lower poles demonstrates strikingly different waveform patterns that might otherwise be overlooked. We report a case of segmental branch renal artery stenosis in which a pulsus parvus et ta...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2001.2.1.57
更新日期:2001-01-01 00:00:00
abstract::As the detection and characterization of lung nodules are of paramount importance in thoracic radiology, various tools for making a computer-aided diagnosis (CAD) have been developed to improve the diagnostic performance of radiologists in clinical practice. Numerous studies over the years have shown that the CAD syst...
journal_title:Korean journal of radiology
pub_type: 杂志文章,评审
doi:10.3348/kjr.2011.12.2.145
更新日期:2011-03-01 00:00:00
abstract::Thermal ablation using radiofrequency is a new, minimally invasive modality employed as an alternative to surgery in patients with benign thyroid nodules and recurrent thyroid cancers. The Task Force Committee of the Korean Society of Thyroid Radiology (KSThR) developed recommendations for the optimal use of radiofreq...
journal_title:Korean journal of radiology
pub_type: 指南,杂志文章
doi:10.3348/kjr.2018.19.4.632
更新日期:2018-07-01 00:00:00
abstract::Radiologic findings of Middle East respiratory syndrome (MERS), a novel coronavirus infection, have been rarely reported. We report a 30-year-old male presented with fever, abdominal pain, and diarrhea, who was diagnosed with MERS. A chest computed tomographic scan revealed rapidly developed multifocal nodular consoli...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2016.17.1.166
更新日期:2016-01-01 00:00:00
abstract::Immunoglobulin G4 (IgG4)-related kidney disease (IgG4-KD) has recently been demonstrated to be an important part of IgG4-related sclerosing disease (IgG4-SD). However, since IgG4-KD is still relatively unfamiliar to radiologists and physicians as compared to IgG4-SD involving other organs, it could, therefore, be easi...
journal_title:Korean journal of radiology
pub_type: 杂志文章,评审
doi:10.3348/kjr.2015.16.5.1056
更新日期:2015-09-01 00:00:00
abstract::Disseminated mycobacterial infection after bacillus Calmette-Guerin (BCG) vaccination is a very rare disorder, occurring mostly in patients with immunologic deficiency. We report a case of disseminated BCG infection in a 16-month-old girl with severe combined immunodeficiency. Plain radiographs showed multiple osteoly...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2000.1.2.114
更新日期:2000-04-01 00:00:00
abstract:OBJECTIVE:To evaluate the safety and clinical efficacy of transcatheter uterine artery embolization (UAE) for post-myomectomy hemorrhage. MATERIALS AND METHODS:We identified eight female patients (age ranged from 29 to 51 years and with a median age of 37) in two regional hospitals who suffered from post-myomectomy he...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2014.15.3.356
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVE:The purpose of our study was to assess whether a review of multiphasic helical CT combined with the previous serial CT images could be helpful to depict a viable tumor in hepatocellular carcinoma treated with transarterial chemoembolization. MATERIALS AND METHODS:Twenty-four consecutive patients with 35 hepa...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2005.6.3.153
更新日期:2005-07-01 00:00:00
abstract:OBJECTIVE:This study aimed to assess the surgical morbidity and mortality of thoracic endovascular repair (TEVAR) as compared with open surgical repair (OSR) for isolated descending thoracic aortic disease. MATERIALS AND METHODS:From January 1, 2006 through May 31, 2010, a total of 68 patients with isolated descending...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2012.13.4.476
更新日期:2012-07-01 00:00:00
abstract::Papillary tumor of the bile duct is characterized by the presence of an intraductal tumor with a papillary surface comprising innumerable frondlike infoldings of proliferated columnar epithelial cells surrounding slender fibrovascular stalks. There may be multiple tumors along the bile ducts (papillomatosis or papilla...
journal_title:Korean journal of radiology
pub_type: 杂志文章,评审
doi:10.3348/kjr.2002.3.1.57
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVE:To retrospectively compare treatment of hepatocellular carcinoma (HCC) with transarterial chemoembolization (TACE) using gelatin sponges or microspheres plus lipiodol-doxorubicin vs. doxorubicin-loaded drug-eluting beads (DEB). MATERIALS AND METHODS:A total of 158 patients with HCC received TACE from Novembe...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2015.16.1.125
更新日期:2015-01-01 00:00:00
abstract::Endoscopic therapy by balloon dilation and placement of multiple large-bore plastic stents is the treatment of choice for benign biliary stricture. This approach is effective but it typically requires multiple endoscopic sessions given the short duration of stent patency. The endoscopic approach for treatment of bile ...
journal_title:Korean journal of radiology
pub_type: 杂志文章,评审
doi:10.3348/kjr.2012.13.S1.S67
更新日期:2012-01-01 00:00:00