Abstract：
:Sepsis is a systemic inflammatory response to suspected or proven infection. Given its importance in terms of morbidity and mortality, a number of initiatives by several professional societies in recent years have led to the development of guidelines for the recognition and timely management of sepsis. The principal elements of the most recent guidelines are summarized in this practice point. These elements include recognition of changes in clinical condition and vital signs, such as fever, tachycardia, and changes in peripheral perfusion, which should raise concern for sepsis; initial stabilization of airway, breathing, and circulation; timely administration of empiric antimicrobial therapy; use of fluid boluses and vasoactive medications; and specific considerations in patients with underlying medical conditions, such as the use of corticosteroids for possible adrenal insufficiency due to hypothalamic-adrenal suppression. Two changes from previous guidelines are the concern for fluid overload, implying the need for clinical re-assessment after administration of each fluid bolus, and the removal of dopamine as the initial vasoactive agent for use in hypotensive paediatric patients, with recommendations for the use of epinephrine or norepinephrine as dictated by the clinical context. This practice point focuses primarily on sepsis management in older infants, children, and youth.
journal_name
Paediatr Child Healthjournal_title
Paediatrics & child healthauthors
Farrell CAdoi
10.1093/pch/pxz178subject
Has Abstractpub_date
2020-11-02 00:00:00pages
475-476issue
7eissn
1205-7088issn
1918-1485pii
pxz178journal_volume
25pub_type
杂志文章abstract：OBJECTIVE:To determine the current prevalence of smoking among First Nations youth living on reserve within the Saskatoon Tribal Council, and to determine the independent risk indicators associated with smoking among First Nations youth. METHODS:Students in grades 5 to 8 attending school within the Saskatoon Tribal Co...
journal_title：Paediatrics & child health
pub_type： 杂志文章
doi：10.1093/pch/16.10.e71
更新日期：2011-12-01 00:00:00
abstract：:Medically unexplained symptoms in young people can present a challenge for primary care physicians to manage. Despite the prevalence of this clinical problem, physicians feel ill-equipped to deal with it. Families may attribute symptoms to an organic cause, despite the absence of identified pathology, and often resist...
journal_title：Paediatrics & child health
pub_type： 杂志文章
doi：
更新日期：2008-07-01 00:00:00
abstract：:Paediatric restless legs syndrome (RLS) treatment is important because RLS's associated sleep disturbance causes significant developmental-behavioural morbidity and impacts family well-being. RLS is associated with brain iron insufficiency and dopaminergic dysfunction. Diagnosis requires fulfillment of diagnostic crit...
journal_title：Paediatrics & child health
pub_type： 杂志文章
doi：10.1093/pch/17.4.193
更新日期：2012-04-01 00:00:00
abstract：:The present paper describes research on the skills and processes associated with word and text reading acquisition in preschool children and during the first years of school. The aim is to provide an overview that gives a sense of the important milestones in language and literacy acquisition. A comparison of children'...
journal_title：Paediatrics & child health
pub_type： 杂志文章
doi：10.1093/pch/11.9.589
更新日期：2006-11-01 00:00:00
abstract：:A 1992 meta-analysis did not find enough evidence to recommend one method of umbilical cord care as the 'best'. However, certain agents were deemed acceptable including triple dye, silver sulfadiazine and antibiotic ointments. In this paper, the authors sought to discover whether there was now evidence to support one ...
journal_title：Paediatrics & child health
pub_type： 杂志文章
doi：10.1093/pch/4.2.105
更新日期：1999-03-01 00:00:00
abstract：:[This corrects the article DOI: 10.1093/pch/pxy072.]. ...
journal_title：Paediatrics & child health
pub_type： 杂志文章,已发布勘误
doi：10.1093/pch/pxy163
更新日期：2019-02-01 00:00:00
abstract：:The present article is intended to inform paediatricians about the associations between ambient air pollution and adverse health outcomes in children within the context of current epidemiological evidence.The majority of the current literature pertains to adverse respiratory health outcomes, including asthma, other re...
journal_title：Paediatrics & child health
pub_type： 杂志文章
doi：
更新日期：2006-10-01 00:00:00
abstract：:Family physicians, paediatricians, nurse practitioners and all primary health care providers are well-positioned in the health care system to provide identification and intervention for developmental delay in early childhood. This can be accomplished through the promotion of healthy child development by supporting chi...
journal_title：Paediatrics & child health
pub_type： 杂志文章
doi：10.1093/pch/13.10.845
更新日期：2008-12-01 00:00:00
abstract：:Maintenance of plasma glucose depends on a normal endocrine system, functional enzyme levels for glycogenolysis, gluconeogenesis and other processes, and there must be an adequate supply of endogenous fat, glycogen and substrates of gluconeogenesis. Neonatal hypoglycemia should be defined as serum glucose less than 2....
journal_title：Paediatrics & child health
pub_type： 杂志文章
doi：10.1093/pch/3.1.16
更新日期：1998-01-01 00:00:00
abstract：Objective:To determine if treatment failure varies based on ROME III classification and adherence to guideline congruent therapy among children diagnosed in an emergency department with functional constipation. Methods:Children aged 1 month to 18 years who were diagnosed with constipation in a paediatric emergency dep...
journal_title：Paediatrics & child health
pub_type： 杂志文章
doi：10.1093/pch/pxy121
更新日期：2019-06-01 00:00:00
abstract：:The ability to communicate effectively with patients and families is paramount for good patient care. This practice point reviews the importance of communicating effectively in cross-cultural encounters. The concept of cultural competence is introduced, along with the LEARN (Listen, Explain, Acknowledge, Recommend, Ne...
journal_title：Paediatrics & child health
pub_type： 杂志文章
doi：10.1093/pch/pxx126
更新日期：2018-02-01 00:00:00
abstract：Aim:To investigate the implementation of amplitude-integrated electroencephalography (aEEG) as bedside monitoring tool of cerebral function in tertiary Canadian Neonatal Intensive Care Units (NICU) over the past decade. Methods:Longitudinal study consisting of online surveys of neonatologists on the use of aEEG in 200...
journal_title：Paediatrics & child health
pub_type： 杂志文章
doi：10.1093/pch/pxz091
更新日期：2019-10-10 00:00:00
abstract：OBJECTIVE:To determine whether reminder notices would improve the timeliness of toddler-age vaccinations. DESIGN:Prospective, randomized, controlled trial. POPULATION STUDIED:Two convenience cohorts of 320 children due to receive either measles-mumps-rubella (MMR) vaccine (at 12 months of age) or diphtheria-pertussis...
journal_title：Paediatrics & child health
pub_type： 杂志文章
doi：
更新日期：1999-09-01 00:00:00
abstract：:[This corrects the article on p. 12 in vol. 20, PMID: 25722635.]. ...
journal_title：Paediatrics & child health
pub_type： 已发布勘误
doi：
更新日期：2015-04-01 00:00:00
abstract：:Clinical trials in paediatric cancer continue to be a key factor in progress toward better treatment and prognosis. Paediatricians and family physicians may be asked by patients and families for their advice regarding participation in such trials. The significant advances in the success of treatment of paediatric canc...
journal_title：Paediatrics & child health
pub_type： 杂志文章
doi：
更新日期：2006-03-01 00:00:00
abstract：BACKGROUND:Night-float systems, in which residents work consecutive nights, have been increasingly adopted in paediatric programs, but may be detrimental to residents' sleep and mood. OBJECTIVE:To describe the self-reported impact of a novel system consisting of two consecutive weeks of 16 h overnight shifts every sec...
journal_title：Paediatrics & child health
pub_type： 杂志文章
doi：10.1093/pch/20.2.77
更新日期：2015-03-01 00:00:00
abstract：:Antimicrobial stewardship is a recent concept that embodies the practical, judicious use of antimicrobials to decrease adverse outcomes from antimicrobials while optimizing the treatment of bacterial infections to reduce the emergence of resistant pathogens. The objectives of the present statement are to illustrate th...
journal_title：Paediatrics & child health
pub_type： 杂志文章
doi：10.1093/pch/19.5.261
更新日期：2014-05-01 00:00:00
abstract：:Mitigating the harmful effects of adverse social conditions is critical to promoting optimal health and development throughout the life course. Many Canadians worry over food access or struggle with household food insecurity. Public policy positions breastfeeding as a step toward eradicating poverty. Breastfeeding ful...
journal_title：Paediatrics & child health
pub_type： 杂志文章
doi：10.1093/pch/pxx067
更新日期：2017-07-01 00:00:00
abstract：:The harmful effects of child poverty are well documented. Despite this, progress in poverty reduction in Canada has been slow. A significant gap exists between what is known about eradicating poverty and its implementation. Paediatricians can play an important role in bridging this gap by understanding and advancing c...
journal_title：Paediatrics & child health
pub_type： 杂志文章,评审
doi：10.1093/pch/20.4.203
更新日期：2015-05-01 00:00:00
abstract：:Helicobacter pylori infection is acquired in childhood and plays a causative role in chronic gastritis, peptic ulcer disease and the development of gastric cancer. The present review focuses on recent advances in the management of H pylori infection in children and provides an update of current Canadian guidelines reg...
journal_title：Paediatrics & child health
pub_type： 杂志文章
doi：10.1093/pch/9.10.709
更新日期：2004-12-01 00:00:00
abstract：:Canadian children and youth travelling overseas face numerous environmental risks, including trauma, extreme temperatures, sun exposure, high altitudes, environmental pollution, and a variety of bites, stings and envenomations. Because skilled emergency response is limited or nonexistent in places where serious illnes...
journal_title：Paediatrics & child health
pub_type： 杂志文章
doi：10.1093/pch/5.7.387
更新日期：2000-10-01 00:00:00
abstract：:Childhood obesity has reached epidemic proportions. Many of these children have risk factors for later disease, including cardiovascular disease. For optimal cardiovascular health, health care professionals must be able to identify children and youth at risk and provide appropriate support as needed. The present artic...
journal_title：Paediatrics & child health
pub_type： 杂志文章
doi：10.1093/pch/14.3.177
更新日期：2009-03-01 00:00:00
abstract：OBJECTIVES:To determine the use and potential interactions of natural health products (NHPs) with conventional medications in children with life-limiting illnesses. METHODS:The present study was a retrospective medical record review of palliative care patients <18 years of age who were admitted for respite care to a C...
journal_title：Paediatrics & child health
pub_type： 杂志文章
doi：10.1093/pch/20.1.23
更新日期：2015-01-01 00:00:00
abstract：:Respiratory syncytial virus (RSV) is recognized as an important cause of childhood morbidity and mortality. Vaccine development has been challenging in young infants and has required the advent of molecular technologies to optimize the safety profile, while maintaining immunogenicity of live-attenuated vaccines. Prote...
journal_title：Paediatrics & child health
pub_type： 杂志文章
doi：10.1093/pch/8.10.605
更新日期：2003-12-01 00:00:00
abstract：Objectives:Children with attention deficit/hyperactivity disorder (ADHD) are frequently treated with psycho-stimulant agents causing a modest but significant increase in blood pressure and heart rate. The objective of this study was to define blood pressure characteristics in children with ADHD treated with a variety o...
journal_title：Paediatrics & child health
pub_type： 杂志文章
doi：10.1093/pch/pxx207
更新日期：2018-09-01 00:00:00
abstract：OBJECTIVE:To determine whether a simple, nonsurgical treatment for congenital ear abnormalities (lop-ear, Stahl's ear, protruding ear, cryptotia) improved the appearance of ear abnormalities in newborns at six weeks of age. METHODS:This is a descriptive case series. All newborns with identified abnormalities were refe...
journal_title：Paediatrics & child health
pub_type： 杂志文章
doi：10.1093/pch/10.6.327
更新日期：2005-07-01 00:00:00
abstract：:Disability is a major public health concern worldwide and the situation for children with disabilities is even more serious. The present article will focus on the issue of children with disabilities in low-income countries. Approximately one-third of the world's disabled population is children and many of these disabl...
journal_title：Paediatrics & child health
pub_type： 杂志文章
doi：10.1093/pch/10.5.269
更新日期：2005-05-01 00:00:00
abstract：:The administration of intravenous (IV) therapy at home is an alternative to hospitalization for treatment of infection and a number of other conditions, and has been demonstrated to be effective and safe, to reduce cost and to improve quality of life. While home IV therapy has many advantages for children, it is not u...
journal_title：Paediatrics & child health
pub_type： 杂志文章
doi：10.1093/pch/16.2.105
更新日期：2011-02-01 00:00:00
abstract：:Within the paediatric population, changing patterns of circumcisions have confounded the epidemiology and presentation of lichen sclerosus (LS). We sought to evaluate the incidence, demographics, and clinical features of patients presenting to a single Albertan paediatric urologist with LS. This retrospective descript...
journal_title：Paediatrics & child health
pub_type： 杂志文章
doi：10.1093/pch/pxy172
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:A checklist that promotes compliance with aseptic technique during line insertion is a component of many care bundles aimed at reducing nosocomial infections among intensive care unit patients. OBJECTIVE:To determine whether the use of bundled interventions that include a checklist during central-line inser...
journal_title：Paediatrics & child health
pub_type： 杂志文章,评审
doi：10.1093/pch/19.4.e20
更新日期：2014-04-01 00:00:00
