Abstract:
:The methanolic extract from the pericarps of Sapindus rarak DC. was found to show pancreatic lipase inhibitory activity (IC50=ca. 614 microg/mL). From the extract, oleanane-type triterpene oligoglycosides, rarasaponins I-III (1-3), and raraoside A (4), were isolated together with 13 known saponins and four known sesquiterpene glycosides. Among them, several saponin constituents including rarasaponins I (1, IC50=131microM) and II (2, 172microM), and raraoside A (4, 151microM) inhibited pancreatic lipase activity, which were stronger than that of theasaponin E(1) (270microM).
journal_name
Phytochemistryjournal_title
Phytochemistryauthors
Morikawa T,Xie Y,Asao Y,Okamoto M,Yamashita C,Muraoka O,Matsuda H,Pongpiriyadacha Y,Yuan D,Yoshikawa Mdoi
10.1016/j.phytochem.2009.06.015subject
Has Abstractpub_date
2009-06-01 00:00:00pages
1166-1172issue
9eissn
0031-9422issn
1873-3700pii
S0031-9422(09)00252-0journal_volume
70pub_type
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