Developmental exposure to PCBs, MeHg, or both: long-term effects on auditory function.

abstract：BACKGROUND:In male rodents, anogenital distance (AGD) provides a sensitive and continuous correlate of androgen exposure in the intrauterine environment and predicts later reproductive success. Some endocrine-disrupting chemicals can alter male reproductive tract development, including shortening AGD, in both rodents a...

journal_title：Environmental health perspectives

authors： Mendiola J,Stahlhut RW,Jørgensen N,Liu F,Swan SH

更新日期：2011-07-01 00:00:00

abstract：:A major challenge in the emerging field of toxicogenomics is to define the relationships between chemically induced changes in gene expression and alterations in conventional toxicologic parameters such as clinical chemistry and histopathology. We have explored these relationships in detail using the rodent uterotroph...

journal_title：Environmental health perspectives

authors： Moggs JG,Tinwell H,Spurway T,Chang HS,Pate I,Lim FL,Moore DJ,Soames A,Stuckey R,Currie R,Zhu T,Kimber I,Ashby J,Orphanides G

更新日期：2004-11-01 00:00:00

abstract：:Reaction of chromium(VI) with one equivalent of ascorbate was studied by electron paramagnetic resonance spectroscopy in the presence of 0.10 M 5,5-dimethyl-1-pyrroline-1-oxide (DMPO) at room temperature in 0.10 M (N-[2-hydroxyethyl]piperazine-N'-[2-ethanesulfonic acid]) (HEPES) and 0.05 M tris(hydroxymethyl)aminometh...

journal_title：Environmental health perspectives

authors： Stearns DM,Courtney KD,Giangrande PH,Phieffer LS,Wetterhahn KE

更新日期：1994-09-01 00:00:00

abstract：INTRODUCTION:Asians, Pacific Islanders, and Native Americans are a potentially high-risk group for dietary exposure to methylmercury through fish consumption. However, blood mercury levels in this group have not been identified in recent reports of the National Health and Nutrition Examination Survey (NHANES) for the y...

journal_title：Environmental health perspectives

authors： Hightower JM,O'Hare A,Hernandez GT

更新日期：2006-02-01 00:00:00

abstract：:Although allergic diseases such as asthma and hay fever are a major cause of morbidity in industrialized countries, most studies have focused on patterns of prevalence among children and adolescents, with relatively few studies on variations in prevalence by race/ethnicity and socioeconomic position among adults. Our ...

journal_title：Environmental health perspectives

authors： Chen JT,Krieger N,Van Den Eeden SK,Quesenberry CP

更新日期：2002-04-01 00:00:00

abstract：:Our desire to understand the potential adverse human health effects of environmental chemical exposure has coincided with an increased understanding of the immune system and an appreciation of its complex regulatory network. This has spawned a broad interest in the area of immunotoxicology within the scientific commun...

journal_title：Environmental health perspectives

authors： Luster MI,Rosenthal GJ

更新日期：1993-04-01 00:00:00

abstract：OBJECTIVES:There are some common occupational agents and exposure circumstances for which evidence of carcinogenicity is substantial but not yet conclusive for humans. Our objectives were to identify research gaps and needs for 20 agents prioritized for review based on evidence of widespread human exposures and potenti...

journal_title：Environmental health perspectives

authors： Ward EM,Schulte PA,Straif K,Hopf NB,Caldwell JC,Carreón T,DeMarini DM,Fowler BA,Goldstein BD,Hemminki K,Hines CJ,Pursiainen KH,Kuempel E,Lewtas J,Lunn RM,Lynge E,McElvenny DM,Muhle H,Nakajima T,Robertson LW,Rothma

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Although from a societal point of view a modal shift from car to bicycle may have beneficial health effects due to decreased air pollution emissions, decreased greenhouse gas emissions, and increased levels of physical activity, shifts in individual adverse health effects such as higher exposure to air pollu...

journal_title：Environmental health perspectives

authors： Johan de Hartog J,Boogaard H,Nijland H,Hoek G

更新日期：2010-08-01 00:00:00

abstract：:We developed a sensitive and accurate analytical method for quantifying methyleugenol (ME) in human serum. Our method uses a simple solid-phase extraction followed by a highly specific analysis using isotope dilution gas chromatography-high resolution mass spectrometry. Our method is very accurate; its limit of detect...

journal_title：Environmental health perspectives

authors： Barr DB,Barr JR,Bailey SL,Lapeza CR Jr,Beeson MD,Caudill SP,Maggio VL,Schecter A,Masten SA,Lucier GW,Needham LL,Sampson EJ

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND:Pesticides have been associated with Parkinson's disease (PD), but there are few data on important exposure characteristics such as dose-effect relations. It is unknown whether associations depend on clinical PD subtypes. OBJECTIVES:We examined quantitative aspects of occupational pesticide exposure associa...

journal_title：Environmental health perspectives

authors： Moisan F,Spinosi J,Delabre L,Gourlet V,Mazurie JL,Bénatru I,Goldberg M,Weisskopf MG,Imbernon E,Tzourio C,Elbaz A

更新日期：2015-11-01 00:00:00

abstract：:Repeated inhalation of silica dust can lead to inflammation and fibrosis in human lung and in experimental animal models. The alveolar macrophage is believed to play a pivotal role in this process. Numerous macrophage-derived growth factors, cytokines, and arachidonic acid metabolites have been shown to contribute to ...

journal_title：Environmental health perspectives

authors： Koren HS,Joyce M,Devlin RB,Becker S,Driscoll K,Madden MC

更新日期：1992-07-01 00:00:00

abstract：:In April 2004, one of the largest aflatoxicosis outbreaks occurred in rural Kenya, resulting in 317 cases and 125 deaths. Aflatoxin-contaminated homegrown maize was the source of the outbreak, but the extent of regional contamination and status of maize in commercial markets (market maize) were unknown. We conducted a...

journal_title：Environmental health perspectives

authors： Lewis L,Onsongo M,Njapau H,Schurz-Rogers H,Luber G,Kieszak S,Nyamongo J,Backer L,Dahiye AM,Misore A,DeCock K,Rubin C,Kenya Aflatoxicosis Investigation Group.

更新日期：2005-12-01 00:00:00

abstract：:comments on S. Patandin et al. : Dietary exposure to polychlorinated biphenyls and dioxins from infancy until adulthood: a comparison between breast-feeding, toddler, and long-term exposure. Environ Health Perspect 107:45-51 (1999). ...

journal_title：Environmental health perspectives

authors： LaKind JS,Filser JG

更新日期：1999-10-01 00:00:00

abstract：:A major goal of studying farmworkers is to better understand how their work environment, including exposure to pesticides, affects their health. Although a number of health conditions have been associated with pesticide exposure, clear linkages have yet to be made between exposure and health effects except in cases of...

journal_title：Environmental health perspectives

authors： McCauley LA,Anger WK,Keifer M,Langley R,Robson MG,Rohlman D

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Phthalates are metabolized and eliminated in urine within hours after exposure. Several reports suggest that concentrations of phthalate metabolites in a spot urine sample can provide a reliable estimation of exposure to phthalates for up to several months. OBJECTIVES:We examined inter- and intraperson and ...

journal_title：Environmental health perspectives

authors： Preau JL Jr,Wong LY,Silva MJ,Needham LL,Calafat AM

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:The presence of pharmaceuticals in aquatic environments and in drinking water has prompted significant public interest regarding potential adverse ecological effects and risks to human health. OBJECTIVES:The Environmental Health Summit held in North Carolina, 10-11 November 2008, explored the issues associa...

journal_title：Environmental health perspectives

authors： Rodriguez-Mozaz S,Weinberg HS

更新日期：2010-07-01 00:00:00

abstract：:The biopersistence of fibers and minerals in the respiratory tract is an important parameter in the toxicity of those materials. The biopersistence of respirable synthetic fibers and minerals in man can be most closely evaluated in an animal model. While acellular and in vitro systems are important for initial evaluat...

journal_title：Environmental health perspectives

authors： Bernstein DM,Mast R,Anderson R,Hesterberg TW,Musselman R,Kamstrup O,Hadley J

更新日期：1994-10-01 00:00:00

abstract：:1,3-Butadiene is a major monomer in the rubber and plastics industry and is one of the highest-production industrial chemicals in the United States. Although not highly acutely toxic to rodents, inhalation of concentrations as low as 6.25 ppm causes tumors in mice. Butadiene is oncogenic in rats, but much higher expos...

journal_title：Environmental health perspectives

authors： Birnbaum LS

更新日期：1993-12-01 00:00:00

abstract：:To assess quantitatively the association between benzene and leukemia, we evaluated the rate of mortality experienced by a cohort occupationally exposed to benzene. Using data from historical air sampling surveys, we estimated the daily benzene exposure for each member of the cohort. The expected number of leukemia de...

journal_title：Environmental health perspectives

authors： Rinsky RA

更新日期：1989-07-01 00:00:00

abstract：:The study reported here presents the results of an investigation of a marsh-cove ecosystem heavily contaminated by cadmium. The most contaminated aquatic sediments were dredged in 1972-73, but the resuspension of the sediments and recycle of water from the dredge spoil resulted in reestablishment of a large contaminat...

journal_title：Environmental health perspectives

authors： Kneip TJ,Hazen RE

更新日期：1979-02-01 00:00:00

abstract：:Free-radical metabolites can be generated metabolically by a one-electron reductase-catalyzed reaction or a "peroxidase" catalyzed oxidation or by photoactivation of a wide variety of aromatic xenobiotics. Radicals may also be generated during lipid peroxidation. Some radicals can react with DNA or bind covalently or ...

journal_title：Environmental health perspectives

authors： O'Brien PJ

更新日期：1985-12-01 00:00:00

abstract：:New technologies are providing innovative ways to reduce sound levels in many areas. Aircraft engineers are finding ways to reduce the noise produced by jet engines, while road builders are using rubber-enhanced pavement to quiet highway noise. Indoor acoustics are benefiting from materials that transform sound waves ...

journal_title：Environmental health perspectives

authors： Manuel J

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Particulate matter (PM) air pollution has been associated with cardiovascular morbidity and mortality, and elevated blood pressure (BP) is a known risk factor for cardiovascular disease. A small number of studies have investigated the relationship between PM and BP and found mixed results. Evidence suggests ...

journal_title：Environmental health perspectives

authors： Mordukhovich I,Wilker E,Suh H,Wright R,Sparrow D,Vokonas PS,Schwartz J

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Phthalates, known endocrine disruptors, may play a role in breast carcinogenesis. Few studies have examined phthalates in relation to breast cancer (BC), and, to our knowledge, none have considered survival following BC. OBJECTIVES:We examined 11 urinary phthalate metabolites, individually and as molar sum ...

journal_title：Environmental health perspectives

authors： Parada H Jr,Gammon MD,Chen J,Calafat AM,Neugut AI,Santella RM,Wolff MS,Teitelbaum SL

更新日期：2018-04-26 00:00:00

abstract：INTRODUCTION:Ambient particulate pollution and traffic have been linked to myocardial infarction and cardiac death risk. Possible mechanisms include autonomic cardiac dysfunction. METHODS:In a repeated-measures study of 46 patients 43-75 years of age, we investigated associations of central-site ambient particulate po...

journal_title：Environmental health perspectives

authors： Zanobetti A,Gold DR,Stone PH,Suh HH,Schwartz J,Coull BA,Speizer FE

更新日期：2010-03-01 00:00:00

abstract：:Dysmenorrhea is a common gynecologic disorder in women of reproductive age. Previous studies have found an association between current cigarette smoking and prevalence of dysmenorrhea. This study investigated the association between exposure to environmental tobacco smoke (ETS) and the occurrence of dysmenorrhea among...

journal_title：Environmental health perspectives

authors： Chen C,Cho SI,Damokosh AI,Chen D,Li G,Wang X,Xu X

更新日期：2000-11-01 00:00:00

abstract：:A combined cytogeneticurine metabolite analysis approach was used to assess potential interactive effects between Fenarimol (FN), a fungicide, and trichloroethylene (TRI), a halogenated solvent. FN was demonstrated to selectively induce P450-2B1 isoforms in different organs of treated mice. Since the rate of metabolis...

journal_title：Environmental health perspectives

authors： Hrelia P,Maffei F,Vigagni F,Fimognari C,Flori P,Stanzani R,Cantelli Forti G

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Exposure mixtures frequently occur in data across many domains, particularly in the fields of environmental and nutritional epidemiology. Various strategies have arisen to answer questions about exposure mixtures, including methods such as weighted quantile sum (WQS) regression that estimate a joint effect o...

journal_title：Environmental health perspectives

authors： Keil AP,Buckley JP,O'Brien KM,Ferguson KK,Zhao S,White AJ

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:The potential impact of microwave radiofrequency electromagnetic fields (RF-EMF) emitted by wireless communication devices on neurocognitive functions of adolescents is controversial. In a previous analysis, we found changes in figural memory scores associated with a higher cumulative RF-EMF brain dose in ad...

journal_title：Environmental health perspectives

authors： Foerster M,Thielens A,Joseph W,Eeftens M,Röösli M

更新日期：2018-07-23 00:00:00

abstract：OBJECTIVE:The World Health Organization is the agency responsible for reporting the Millennium Development Goal (MDG) indicator "percentage of population using solid fuels." In this article, we present the results of a comprehensive assessment of solid fuel use, conducted in 2005, and discuss the implications of our fi...

journal_title：Environmental health perspectives

authors： Rehfuess E,Mehta S,Prüss-Ustün A

更新日期：2006-03-01 00:00:00