Influence of bathing or washing on skin barrier function in newborns during the first four weeks of life.

Abstract:

BACKGROUND AND OBJECTIVES:After birth, skin barrier function is in state of flux and at risk of dysfunction. In a prospective clinical study, we compared the effects of 2 standard cleansing procedures on skin barrier function in newborns. METHODS:Fifty-seven healthy full-term neonates aged < or = 48 h were randomly assigned to either a bathing group (group B; n = 29), who were bathed with clear water twice weekly, or to a washing group (group W; n = 28), who were washed with a washcloth moistened with clear water twice weekly. Transepidermal water loss (TEWL), skin pH, stratum corneum hydration (SCH) and sebum production were measured at days 2, 7 and 28 of life on the forehead, abdomen, upper leg and buttock. RESULTS:Group B showed significantly lower TEWL on the buttock and higher SCH on the abdomen and forehead compared to group W at day 28. CONCLUSIONS:Both skin care regimens do not harm the adaptation of the skin barrier in healthy neonates within the first 4 weeks of life. Skin barrier function differentiates after birth in a regionally specific fashion.

journal_name

Skin Pharmacol Physiol

authors

Garcia Bartels N,Mleczko A,Schink T,Proquitté H,Wauer RR,Blume-Peytavi U

doi

10.1159/000235552

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

248-57

issue

5

eissn

1660-5527

issn

1660-5535

pii

000235552

journal_volume

22

pub_type

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