Abstract:
:Mouse leukosialin, previously known as the 3E8 antigen, is expressed primarily on cells of the hematopoietic and lymphoid lineages and is shown to be the mouse homologue to the human leukosialin/sialophorin and rat W3/13 molecules. A partial leukosialin cDNA clone was isolated via cross-species hybridization with a portion of a human leukosialin cDNA. This mouse cDNA clone was used to demonstrate that the leukosialin isoforms are encoded by a single mRNA species of approximately 4.2 kilobases (kb) and that the leukosialin gene is located on chromosome 7. Based on these results, mouse leukosialin is given the designation Ly48.
journal_name
Immunogeneticsjournal_title
Immunogeneticsauthors
Baecher CM,Dorfman KS,Mattei MG,Frelinger JGdoi
10.1007/BF02115004subject
Has Abstractpub_date
1990-01-01 00:00:00pages
307-14issue
5-6eissn
0093-7711issn
1432-1211journal_volume
31pub_type
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