Abstract：
:Nephrogenic systemic fibrosis (NSF) is a highly debilitating scleroderma-like disease occurring exclusively in patients with severe or end-stage renal failure. Since the recognition of a link between gadolinium chelates (GCs) used as contrast agents for MR imaging and NSF by two independent European teams in 2006, numerous studies have described the clinical issues and investigated the mechanism of this disease. So far the most commonly reported hypothesis is based on the in vivo dechelation of GCs. The physicochemical properties of GCs, especially their thermodynamic and kinetic stabilities, are described in the present article. High kinetic stability provided by the macrocyclic structure, combined with high thermodynamic stability, minimizes the amount of free gadolinium released in the body. The current hypotheses regarding the pathophysiologic mechanism are critically discussed.
journal_name
Radiol Clin North Amjournal_title
Radiologic clinics of North Americaauthors
Idée JM,Port M,Dencausse A,Lancelot E,Corot Cdoi
10.1016/j.rcl.2009.06.006subject
Has Abstractpub_date
2009-09-01 00:00:00pages
855-69, viiissue
5eissn
0033-8389issn
1557-8275pii
S0033-8389(09)00098-0journal_volume
47pub_type
杂志文章,评审abstract：:Transaxial computed tomographic (CT) data can be used to generate images rapidly in the coronal and sagittal planes (two-dimensional CT) and create simulated three-dimensional images. The techniques and advantages of an integrated two-dimensional/three-dimensional CT approach to musculoskeletal trauma are illustrated ...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1989-09-01 00:00:00
abstract：:MR and CT are complementary studies in evaluating inflammatory disease or neoplasms of the mastoid and middle ear cavities. CT should be performed prior to MR in the evaluation of patients with primary temporal bone pathology because of its ability to detect and delineate both soft tissue and bony abnormalities. CT sh...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1989-03-01 00:00:00
abstract：:Musculoskeletal disease occurs in association with inflammatory bowel disorders including Crohn's disease and ulcerative colitis, as well as with Whipple's disease; with enteritis caused by Salmonella, Shigella, and Yersinia; and also following intestinal bypass surgery. Extraintestinal causes of musculoskeletal alter...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:Stress cardiac magnetic resonance imaging can provide valuable information for the diagnosis and management of ischemic heart disease (IHD). It plays an important role in the initial diagnosis in patients with acute chest pain, in the diagnosis of complications post myocardial infarction (MI), in the assessment of the...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.rcl.2014.11.006
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abstract：:The overhead throwing motion is a complex sequence of maneuvers that requires coordinated muscle activity in the upper and lower extremities. The shoulder and elbow are subject to multidirectional forces and are particularly vulnerable to injury during specific phases of the overhead throwing motion. Ligamentous, tend...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.rcl.2012.09.016
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abstract：:MR imaging has become the definitive diagnostic procedure for the evaluation of suspected spinal dysrhaphic processes. Techniques for spinal MR imaging are discussed and MR findings in patients with surgically verified dysrhaphic spinal lesions are reviewed. ...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1988-03-01 00:00:00
abstract：:Mammography has had a major impact on the earlier detection, treatment options, and management decisions and survival and mortality rates of breast cancer. Consequences include overwhelming demand for mammography; problems with optimum response by radiology; limited availability of the examination, especially to the s...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:Magnetic resonance (MR) imaging of the pancreas is useful as both a problem-solving tool and an initial imaging examination of choice. With newer imaging sequences such as diffusion-weighted imaging, MR offers improved ability to detect and characterize lesions and identify and stage tumors and inflammation. MR cholan...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.rcl.2014.02.006
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abstract：:The diagnosis of PHPV is often made difficult by its extremely broad array of clinical manifestations, its etiologic heterogeneity, and frequently opaque ocular media. The CT and MR findings are discussed in terms of how they can be of use in the differential diagnosis of PHPV. The strengths and weaknesses of each of ...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1987-07-01 00:00:00
abstract：:The applications for FDG-PET imaging are rapidly growing and accepted in the field of oncology. FDG-PET imaging does not replace other imaging modalities, such as CT, but seems to be very helpful in specific situations where CT has known limitations, such as differentiation of benign from malignant indeterminate lesio...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0033-8389(05)70319-5
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abstract：:The pathologic conditions that involve the TMJ are similar to those conditions that involve other joints in the body. Therefore, many of the radiologic characteristics of these diseases are also similar. Nevertheless, because the articular surface of the condyle is an important site of mandibular growth, leading to se...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:Although a specific diagnosis of the calcified liver mass may not always be possible, there are some morphologic imaging features that help to indicate the diagnosis (Table 1). The radiologist needs to be aware of the wide spectrum of diseases of the liver that can calcify, and the most common causes. Pathologic corre...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0033-8389(05)70030-0
更新日期：1998-03-01 00:00:00
abstract：:The small bowel is subject to a variety of surgical interventions for the treatment of a broad spectrum of disease processes. Most operative procedures applied to the small bowel are straightforward techniques encumbered by few complications, whereas other procedures are considerably more complex and can be associated...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0033-8389(02)00119-7
更新日期：2003-03-01 00:00:00
abstract：:In the appropriate clinical setting of pituitary hyperfunction or hypofunction, visual field deficit, or cranial nerve palsy, imaging of the pituitary is necessary. This article reviews the normal appearance of the pituitary and its surroundings, emphasizing magnetic resonance imaging. Typical and variant appearances ...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.rcl.2011.02.012
更新日期：2011-05-01 00:00:00
abstract：:Diagnostic confirmation through tissue sampling plays a central role in managing patients with suspected lung malignancy. Tissue samples may be obtained in various ways using bronchoscopy, computed tomography guidance, or surgery. Multidisciplinary discussion between members of the lung cancer care team is helpful in ...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.rcl.2012.05.001
更新日期：2012-09-01 00:00:00
abstract：:Fracture classification systems are used on a daily basis in any busy orthopedic clinic. They are an essential means by which physicians communicate, make treatment decisions, estimate prognosis, and report and compare results. Until recently, these classifications have been designed, accepted, and utilized without fo...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1997-05-01 00:00:00
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journal_title：Radiologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1983-12-01 00:00:00
abstract：:Computed tomography (CT) provides an important perspective in patients with inflammatory bowel disease that often has a profound influence on the therapeutic decision-making process. By virtue of its ability to image the bowel wall, serosa, and mesentery directly and noninvasively, CT can diagnose infectious and infla...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1989-07-01 00:00:00
abstract：:Scrotal ultrasound is now the first and only imaging examination necessary to evaluate the scrotal contents. This article first discusses normal scrotal anatomy, and then examines the imaging findings of various malignant and benign scrotal masses. Other topics include cryptorchidism, extratesticular abnormalities, an...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1996-11-01 00:00:00
abstract：:The historical, epidemiologic, clinical, and pathologic features of the phakomatoses are briefly reviewed in this article. The central nervous system manifestations of the phakomatoses on MR also are illustrated and described. ...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1988-07-01 00:00:00
abstract：:Monoclonal gammopathy of unknown significance (MGUS) is a clinically asymptomatic premalignant clonal plasma cell or lymphoplasmacytic proliferative disorder. Smoldering multiple myeloma, also called asymptomatic multiple myeloma, is an intermediate stage between MGUS and symptomatic multiple myeloma. As the name impl...
journal_title：Radiologic clinics of North America
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abstract：:The sella and parasellar region, found between the anterior and central skull base, represents the central aspect of the skull base. Given the location of the pituitary gland in this location, small lesions in this location may have major physiologic effects on the human body. This article reviews the anatomy, develop...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.rcl.2016.09.002
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abstract：:In single-center trials across 42,838 examinations, 150 (0.35%) cancers were identified only sonographically in average-risk women. Over 90% of the 126 women with sonographically depicted cancers had dense or heterogeneously dense parenchyma. Of the 150 cancers, 141 (94%) were invasive, with a mean size of 9 to 11 mm ...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.rcl.2004.04.003
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abstract：:Multidetector computed tomography (MDCT) offers an important noninvasive imaging modality for confirmation and further characterization of primary lung and large airway neoplasms encountered in pediatric patients. Children represent a unique challenge in imaging, not only because of unique patient factors (eg, inabili...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.rcl.2013.04.005
更新日期：2013-07-01 00:00:00
abstract：:Imaging plays a major role in the evaluation of patients who present to the emergency department with acute left upper quadrant (LUQ) pain. Multidetector computed tomography is currently the primary modality used for imaging these patients. The peritoneal reflections, subperitoneal compartment, and peritoneal spaces o...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.rcl.2015.06.003
更新日期：2015-11-01 00:00:00
abstract：:Technical advances in high-resolution ultrasound have brought ultrasound to the forefront of thyroid imaging. Despite the seeming similarity in the imaging appearance of diffuse thyroid diseases, the radiologist should be able to identify patients with diffuse thyroid abnormality, be aware of the spectrum of the imagi...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.rcl.2011.02.002
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abstract：:From technical and interpretative perspectives, upper extremity computed tomographic angiography (CTA) is one of the more challenging vascular CTA applications. Synchronizing the relatively large scan coverage with a single bolus of contrast medium requires precise selection of acquisition and contrast delivery parame...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.rcl.2010.02.022
更新日期：2010-03-01 00:00:00
abstract：:Liver transplant is the treatment of choice for end-stage liver disease. Management of transplant patients requires a multidisciplinary approach, with radiologists playing a key role in identifying complications in both symptomatic and asymptomatic patients. Ultrasonography remains the investigation of choice for the ...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.rcl.2015.09.004
更新日期：2016-03-01 00:00:00
abstract：:Central nervous system complications in AIDS patients are common and often the cause of severe morbidity and mortality. Most symptomatic central nervous system complications in AIDS patients involve the brain, principally in the form of HIV encephalitis, various other forms of infection, or development of neoplasms. T...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1997-09-01 00:00:00
abstract：:Traumatic injury to the major vessels of the head and neck can result in potentially devastating neurologic sequelae. Until recently, conventional angiography was the primary imaging modality used to evaluate these often challenging patients. Advances in cross-sectional imaging have improved the ability to screen for ...
journal_title：Radiologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.rcl.2005.08.003
更新日期：2006-01-01 00:00:00
