Impact of histological Oral Tongue Cancer margins on locoregional recurrence: A multi-centre retrospective analysis.

abstract：:Similar to actors changing costumes during a performance, cancer cells undergo many rapid changes during the process of tumor metastasis, including epithelial-mesenchymal transition (EMT), acquisition of cancer stem cells (CSCs) properties, and mesenchymal-epithelial transition (MET). Such changes allow the tumor to c...

journal_title：Oral oncology

authors： Zhou C,Liu J,Tang Y,Liang X

更新日期：2012-11-01 00:00:00

abstract：PURPOSE:To describe patterns of failure (POF) after reirradiation (reRT) with intensity modulated radiation therapy (IMRT) for recurrent/second primary squamous cell carcinoma of the head and neck. METHODS:From 08/2004-02/2013, 75 consecutive patients received reRT with IMRT. Gross tumor was generally treated with a 5...

journal_title：Oral oncology

authors： Margalit DN,Rawal B,Catalano PJ,Haddad RI,Goguen LA,Annino DJ,Limaye SA,Lorch JH,Lavigne AW,Schoenfeld JD,Sher DJ,Tishler RB

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVES:Prior studies suggest that oxaliplatin is unique among platinum chemotherapy drugs in its ability to enhance anti-tumor immunity, but the immune mechanisms of different platinum chemotherapy drugs have not been previously compared in preclinical models of head and neck squamous cell carcinoma (HNSCC). MATER...

journal_title：Oral oncology

authors： Park SJ,Ye W,Xiao R,Silvin C,Padget M,Hodge JW,Van Waes C,Schmitt NC

更新日期：2019-08-01 00:00:00

abstract：:Mel-CAM (CD146) is a cell-cell adhesion protein found in normal and tumoral tissues. The aim of this study was to analyse Mel-CAM expression in mucoepidermoid carcinoma (MEC), and assess its importance in prognosis and its utility in differentiating high-grade MEC from squamous cell carcinoma (SCC). Immunohistochemica...

journal_title：Oral oncology

authors： Pires FR,Shih IeM,da Cruz Perez DE,de Almeida OP,Kowalski LP

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVES:Dysphagia is a common and debilitating side effect of chemoradiotherapy. Assessment is difficult; swallowing is multifactorial and studies choose from a range of dysphagia assessments. This study intended to investigate the relationship between swallowing assessments of dysphagia in a cohort of patients and ...

journal_title：Oral oncology

authors： Pedersen A,Wilson J,McColl E,Carding P,Patterson J

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:Elective neck dissection (END) for salvage laryngectomy remains controversial due to variability in reported occult nodal metastasis rates and postoperative complications. We performed a meta-analysis to examine the role of END for treatment of the clinically N0 (cN0) neck in the salvage setting. METHODS:A P...

journal_title：Oral oncology

authors： Lin C,Puram SV,Bulbul MG,Sethi RK,Rocco JW,Old MO,Kang SY

更新日期：2019-09-01 00:00:00

abstract：:Prophylactic internal fixation (PIF), with a bone plate in either the anterior (over the section defect) or posterior (on intact cortex) position, has substantially reduced the incidence of fracture at the donor site of the radial osteocutaneous free flap. This study uses the sheep tibia model to compare the effective...

journal_title：Oral oncology

authors： Avery CM,Skidmore M,Peden A,Pan J

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:To identify functional outcome and orbital complication rate of the preserved orbit and to identify predictors of orbital impairment in periorbital free flap reconstruction. MATERIALS AND METHODS:A retrospective review was conducted on patients undergoing orbit-sparing surgery with periorbital free flap reco...

journal_title：Oral oncology

authors： Philips R,Topf MC,Graf A,Krein H,Heffelfinger R,Luginbuhl A,Curry J

更新日期：2019-11-01 00:00:00

abstract：:To assess the prognostic value of apoptosis, proliferation and clinical factors in squamous cell carcinoma of the oropharynx after radical surgery and postoperative radiotherapy (RT). Between 1985 and 1995, a total of 82 patients with 84 tumors were entered onto the study. Forty-two primary tumors (50%) involved the t...

journal_title：Oral oncology

authors： Grabenbauer GG,Suckorada O,Niedobitek G,Rödel F,Iro H,Sauer R,Rödel C,Schultze-Mosgau S,Distel L

更新日期：2003-07-01 00:00:00

abstract：:This research aims to give a new insight to the relationship between host local immune response and the biological behaviour of the tumor by evaluating of intratumoral natural killer (NK) cells and tumor necrosis factor-alpha (TNFalpha) expressions in oral squamous cell carcinomas. New paraffin sections of the deepest...

journal_title：Oral oncology

authors： Türkseven MR,Oygür T

更新日期：2010-05-01 00:00:00

abstract：:ED-B fibronectin (ED-B FN), a glycoprotein involved in cell adhesion and migration, is expressed in fetal and neoplastic tissues and absent in their normal counterparts. The aim of this study is to evaluate the expression of this glycoprotein in relation to the histological and clinical data and to determine whether i...

journal_title：Oral oncology

authors： Mhawech P,Dulguerov P,Assaly M,Ares C,Allal AS

更新日期：2005-01-01 00:00:00

abstract：:Histological assessment is an essential tool in the diagnosis and guidance of the treatment of various diseases, in particular cancer, of the head and neck. Recent major advances in optical imaging techniques have made it possible to acquire high-resolution in vivo images at the cellular scale. Confocal endomicroscopy...

journal_title：Oral oncology

authors： Abbaci M,Breuskin I,Casiraghi O,De Leeuw F,Ferchiou M,Temam S,Laplace-Builhé C

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVES:Several studies have investigated the relationship between the use of dentures and the duration of denture use and cancer development. Of particular interest is whether ill-fitting dentures increase the likelihood of the development of oral cancer. We conducted a meta-analysis to determine the relationship b...

journal_title：Oral oncology

authors： Manoharan S,Nagaraja V,Eslick GD

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Adenoid cystic carcinomas (ACC) are characterized by high rate of local recurrence and late distant metastasis. Chromosomal changes in the evolution from primary tumors to metastatic disease of ACC have not been appointed. Here we investigated the chromosomal alterations of 53 primary tumors from...

journal_title：Oral oncology

authors： Cordesmeyer R,Laskawi R,Schliephake H,Kauffmann P,Beck J,Bornemann-Kolatzki K,Schütz E,Ströbel P,Kueffer S,Fichtner A,Bremmer F

更新日期：2020-04-01 00:00:00

abstract：:Ameloblastoma is a rare human disease of benign neoplasm odontogenic tumor with a lower prevalence but higher recurrence rate. Etiology of ameloblastoma is not fully understood thus lacks implementation of curative treatments. One of the proposed models of evolution of ameloblastoma is related to alteration in DNA dam...

journal_title：Oral oncology

authors： Toprani SM

更新日期：2020-09-01 00:00:00

abstract：:We hope to establish a new readmission prediction score for patients with head and neck cancer (HNC) after major cancer surgery. A retrospective cohort study was conducted from the clinical and cancer registry data at Kaohsiung Veterans General Hospital. We included the data of patients with newly diagnosed HNC who un...

journal_title：Oral oncology

authors： Yin CH,Kang BH,Liu WS,Pan LF,Chen HM,Lee CC

更新日期：2020-09-01 00:00:00

abstract：:Salivary duct carcinoma (SDC) is a rare, aggressive salivary malignancy that is often diagnosed at an advanced stage. Previously, little was known about outcomes of this disease due to its rarity. In the past several years, much has been learned about salivary duct carcinoma after publication of outcomes from several ...

journal_title：Oral oncology

authors： Schmitt NC,Kang H,Sharma A

更新日期：2017-11-01 00:00:00

abstract：:Parapharyngeal space tumours are rare and most clinicians will only see a small number during their career. We performed a systematic review of 1143 parapharyngeal space tumors published in the past 20 years to increase cumulative experience. A systematic literature review was performed and data on histological diagno...

journal_title：Oral oncology

authors： Riffat F,Dwivedi RC,Palme C,Fish B,Jani P

更新日期：2014-05-01 00:00:00

abstract：:The hormonal regulation of Na+,K(+)-ATPase enzyme activities and induction of the alpha subunit protein of the enzyme in the human submandibular gland (HSG) were studied by use of cultured HSG cells. We treated HSG cells with thyroid hormone, androgen, mineralocorticoid, and glucocorticoid, singly or in combination. 3...

journal_title：Oral oncology

authors： Kurihara K,Tajima Y,Kawasaki M,Ueha T

更新日期：1999-07-01 00:00:00

abstract：:Tubulopapillary hidradenoma-like tumor of the mandible is extremely rare, with only 3 cases published in the English-language literature. The clinicopathological characteristics and histogenesis of this tumor are unclear. Few pathologists and perhaps fewer clinicians are familiar with this entity, and it is likely und...

journal_title：Oral oncology

authors： Zeng M,Guo X,Chen X,Yang S

更新日期：2020-01-01 00:00:00

abstract：:Costimulatory molecules have complementary effects on T-cell activation and their balance may control the development of oral cancer. The aim of this study was to determine the relevance of cytotoxic T-lymphocyte antigen 4 (CTLA-4), CD28 and inducible costimulator (ICOS) polymorphisms in oral squamous cell carcinoma (...

journal_title：Oral oncology

authors： Kämmerer PW,Toyoshima T,Schöder F,Kämmerer P,Kuhr K,Brieger J,Al-Nawas B

更新日期：2010-07-01 00:00:00

abstract：:Quality of life evaluation is an important measure of outcome following the treatment of head and neck cancer. The aim of this study was to evaluate the quality of life of patients undergoing primary surgery for oral and oropharyngeal squamous cell carcinoma. 50 consecutive patients with previously untreated oral canc...

journal_title：Oral oncology

authors： Rogers SN,Humphris G,Lowe D,Brown JS,Vaughan ED

更新日期：1998-05-01 00:00:00

abstract：:To define the role of surgical management of lung metastases in ACC. Twenty ACC patients referred to lung metastasectomy were retrospectively reviewed. Twenty-six operations were performed; at the first metastasectomy, a resection with clear margins (R0) was achieved in 11 patients (55%), 3 are alive and well. Four ou...

journal_title：Oral oncology

authors： Locati LD,Guzzo M,Bossi P,Massone PP,Conti B,Fumagalli E,Bareggi C,Cantù G,Licitra L

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVES:Angiotensin I-converting enzyme (ACE), a type I cell surface zinc metallopeptidase, is differentially expressed in several malignancies and plays a role in tumor cell proliferation, tumor cell migration, angiogenesis, and metastatic behavior. We aimed to investigate the effects of ACE gene (rs1799752) varian...

journal_title：Oral oncology

authors： Liu YT,Lin LW,Chen CY,Wang CP,Liu HP,Houng JY,Chung FM,Shieh TY

更新日期：2012-12-01 00:00:00

abstract：:Hyalinizing clear cell carcinoma (HCCC) is a recently described low-grade carcinoma of the salivary glands presenting two main histological features: clear neoplastic cells and prominent hyalinized stroma. Our aim was to characterize the composition of the hyalinized stroma in three cases of HCCC. An immuno-histochemi...

journal_title：Oral oncology

authors： Félix A,Rosa JC,Nunes JF,Fonseca I,Cidadão A,Soares J

更新日期：2002-06-01 00:00:00

abstract：:Cancer of the oropharynx has attracted considerable attention in recent years given: (1) an increasing incidence in selected populations over the past three decades; (2) the discovery of human papillomavirus (HPV) infection as the driver of the increase, as opposed to the traditional risk factors such as tobacco (smok...

journal_title：Oral oncology

authors： Kreimer AR,Chaturvedi AK,Alemany L,Anantharaman D,Bray F,Carrington M,Doorbar J,D'Souza G,Fakhry C,Ferris RL,Gillison M,Neil Hayes D,Hildesheim A,Huang SH,Kowalski LP,Lang Kuhs KA,Lewis J Jr,Lowy DR,Mehanna H,Ness A

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Head and neck mucosal melanoma (HNMM) is a rare and aggressive disease with a high metastatic potential. Two staging systems are currently available: one specific to HNMM (mmTNM) and one specific to primary tumour sites (sccTNM). Our main objective was to assess the prognostic value of both of these classifi...

journal_title：Oral oncology

authors： Moya-Plana A,Mangin D,Dercle L,Taouachi R,Casiraghi O,Ammari S,Nguyen F,Temam S,Robert C,Gorphe P

更新日期：2019-10-01 00:00:00

abstract：:We performed a meta-analysis to evaluate the role of (18)F-fluorodeoxyglucose positron emission tomography/computed tomography ((18)FDG-PET/CT) in detecting distant metastases and second primary cancers in patients with head and neck cancer (HNC) at staging. Studies about (18)FDG-PET/CT for detecting distant metastase...

journal_title：Oral oncology

authors： Xu GZ,Guan DJ,He ZY

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVES:The objective of this network meta-analysis is to optimize the prophylactic treatment for radiotherapy-induced oral mucositis in patients with head and neck cancer (HNSCC) receiving postoperative or definitive radiotherapy with or without chemotherapy. MATERIALS AND METHODS:We searched electronic databases ...

journal_title：Oral oncology

authors： Peng H,Chen BB,Chen L,Chen YP,Liu X,Tang LL,Mao YP,Li WF,Zhang Y,Lin AH,Sun Y,Ma J

更新日期：2017-12-01 00:00:00

abstract：:The effect of meat and fat in laryngeal carcinogenesis was examined in a case-control study carried out in Uruguay in the time period 1998-1999. One-hundred and forty patients with squamous cell laryngeal carcinoma and 420 hospitalized patients, afflicted with conditions not related with tobacco smoking, alcohol drink...

journal_title：Oral oncology

authors： Oreggia F,De Stefani E,Boffetta P,Brennan P,Deneo-Pellegrini H,Ronco AL

更新日期：2001-02-01 00:00:00