Endophthalmitis in Eyes with Osteo-odonto Keratoprosthesis.

Abstract:

:Aim: To analyze the incidence, microbiological profile, risk factors, and outcomes in eyes with osteo-odonto keratoprosthesis (OOKP) developing endophthalmitis. Methods & material: Retrospective review of medical records of patients presenting between 2003 and 2013 with OOKP and endophthalmitis was undertaken after obtaining IRB approval. Patient demographics, clinical features, microbiological evaluation, treatment details, and outcomes were analyzed. Results: Of 92 eyes with OOKP, 8 (9%) had endophthalmitis. Indications for OOKP included Steven-Johnson syndrome (SJS; n = 6; 75%) and chemical injuries (n = 2; 25%). The mean duration from OOKP surgery to endophthalmitis was 49.4 ± 32.3 months. Seven of eight eyes had associated laminar resorption. Endophthalmitis resolved with conservative management in three eyes. Lamina removal was required in three eyes; one eye underwent evisceration. At presentation, mean BCVA was 2.76 ± 0.24 logMAR that improved to 2.48 ± 1.0 logMAR after intervention. Mean follow-up was 12.6 ± 13.2 months. Conclusion: Endophthalmitis portends a grave prognosis for eyes with OOKP. The most important risk factors are SJS (75%) and lamina resorption (88%).

journal_name

Ocul Immunol Inflamm

authors

Rishi P,Rishi E,Manchegowda P,Iyer G,Srinivasan B,Agarwal S

doi

10.1080/09273948.2020.1770807

subject

Has Abstract

pub_date

2020-10-07 00:00:00

pages

1-5

eissn

0927-3948

issn

1744-5078

pub_type

杂志文章
  • A Focus on the Epidemiology of Uveitis.

    abstract:PURPOSE:Uveitis is a common, sight-threatening inflammatory ocular disease and includes multiple heterogeneous clinical entities. The prevalence of various types of uveitis depends upon multiple factors, such as age, sex, race, geographic distribution, environmental influence, genetics, and social habits. Epidemiologic...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章,评审

    doi:10.1080/09273948.2016.1196713

    authors: Tsirouki T,Dastiridou A,Symeonidis C,Tounakaki O,Brazitikou I,Kalogeropoulos C,Androudi S

    更新日期:2018-01-01 00:00:00

  • Use of a high infusion rate to prevent posterior dislocation of fluocinolone acetonide implant during surgical removal.

    abstract:PURPOSE:To describe a strategy for reducing the risk of posterior dislocation of a fluocinolone implant during exchange or removal. DESIGN:Case report and in vitro model. METHODS:Description of a surgical case and an in vitro experiment evaluating the role of infusion pressure in maintaining implant stability in surg...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2011.553980

    authors: Wan W,Stewart JM

    更新日期:2011-06-01 00:00:00

  • A double-masked, randomized study to investigate the safety and efficacy of daclizumab to treat the ocular complications related to Behçet's disease.

    abstract:PURPOSE:To investigate the safety and efficacy of daclizumab (Zenapax, humanized anti-Tac, HAT) in controlling the ocular manifestations of Behçet's disease. DESIGN:Randomized, placebo-controlled, double-masked clinical trial. PARTICIPANTS:Seventeen participants with Behçet's disease experiencing at least two prior o...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章,随机对照试验

    doi:10.1080/09273940701299370

    authors: Buggage RR,Levy-Clarke G,Sen HN,Ursea R,Srivastava SK,Suhler EB,Altemare C,Velez G,Ragheb J,Chan CC,Nussenblatt RB,Bamji AT,Sran P,Waldmann T,Thompson DJ

    更新日期:2007-03-01 00:00:00

  • Subcutaneous Tocilizumab for Cystoid Macular Edema Secondary to Juvenile Idiopathic Arthritis (JIA)-associated Uveitis: A Case Report.

    abstract::Purpose: To report a case of cystoid macular edema (CME) secondary to juvenile idiopathic arthritis (JIA)-associated uveitis. Case report: 26-year-old female patient presented with CME in both eyes. CME became refractory and TCZ-IV was initiated. After 12 infusions was stopped because grade 1 neuropenia developed. On ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2019.1644350

    authors: Adán A,Moll-Udina A,Ramirez J,Llorenç V

    更新日期:2019-10-07 00:00:00

  • Tocilizumab for the Treatment of Behçet Uveitis that Failed Interferon Alpha and Anti-Tumor Necrosis Factor-Alpha Therapy.

    abstract:PURPOSE:To report the results of tocilizumab (TCZ) treatment in patients with Behçet uveitis (BU) who had failed conventional, interferon alpha, and anti-Tumor necrosis factor-alpha therapy. METHODS:We reviewed the records of five patients with BU treated with monthly infusions of TCZ 8 mg/kg. Outcome measures were vi...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2017.1355471

    authors: Eser Ozturk H,Oray M,Tugal-Tutkun I

    更新日期:2018-01-01 00:00:00

  • The Use of Optical Coherence Tomography Angiography in the Diagnosis of Inflammatory Type 1 Choroidal Neovascularization Secondary to Tuberculosis: A Case Report.

    abstract::Purpose: To report a case of choroidal neovascularization (CNV), which was not obvious with dye angiography but was detected with optical coherence tomography angiography (OCTA).Methods: A 50-year-old female presented with decreased vision in her right eye. Funduscopic examination revealed a swollen hyperemic disc, pe...

    journal_title:Ocular immunology and inflammation

    pub_type: 信件

    doi:10.1080/09273948.2020.1754862

    authors: Demirel S,Yalçındağ N,Yanık Ö,Batıoğlu F,Özmert E

    更新日期:2020-05-27 00:00:00

  • Polymerase chain reaction for diagnosis of herpetic intraocular inflammation.

    abstract::The authors present a polymerase chain reaction method for rapid and direct diagnosis of herpetic intraocular infections using small volume samples of intraocular fluid from 29 patients with various intraocular inflammatory diseases and 24 controls with senile cataract. Of six patients with early acute retinal necrosi...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273949309086545

    authors: Usui M,Usui N,Goto H,Minoda H,Rai T

    更新日期:1993-01-01 00:00:00

  • Safety and efficacy of intravitreal triamcinolone acetonide for uveitic macular edema.

    abstract:BACKGROUND:To evaluate the safety and efficacy of intravitreal triamcinolone acetonide (TA) for treating macular edema secondary to non-infectious uveitis. METHODS:Retrospective review of sixteen patients (20 eyes) with chronic cystoid macular edema (CME) as a consequence of controlled intermediate uveitis, posterior ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273940590933511

    authors: Androudi S,Letko E,Meniconi M,Papadaki T,Ahmed M,Foster CS

    更新日期:2005-04-01 00:00:00

  • The Effect of Androgens on Proinflammatory Cytokine Secretion from Human Ocular Surface Epithelial Cells.

    abstract::Purpose: The purpose of this study is to explore the effects of dihydrotestosterone (DHT) on lipopolysaccharide (LPS)-induced proinflammatory cytokine release in human ocular surface epithelial cells exposed to LPS and LPS-binding protein (LBP).Methods: Immortalized human corneal, conjunctival, and meibomian gland epi...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2019.1686155

    authors: Marangoz D,Oner C,Schicht M,Turgut Cosan D,Paulsen F,Yildiz E,Zibandeh N,Sahin A

    更新日期:2019-11-18 00:00:00

  • Survival of corneal grafts after severe burns of the eye.

    abstract::The authors investigated 32 human corneal buttons of patients suffering from severe eye burns. The keratoplasties were performed in different periods after the burn and collected within five years. Grafts were followed-up until they failed because of ulceration or until rehabilitating keratoplasties were performed. Ea...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273949409057077

    authors: Becker J,Salla S,Redbrake C,Schrage NF,Reim M

    更新日期:1994-01-01 00:00:00

  • Clinical Follow-up of Patients with Behçet Uveitis after Discontinuation of Infliximab Therapy.

    abstract:PURPOSE:To evaluate the clinical course of patients with Behçet uveitis after discontinuation of infliximab (IFX) therapy. METHODS:Medical records of eight patients who discontinued treatment between 2010 and 2018 were retrospectively analyzed. The main outcome measures were frequency of uveitis attacks per year, best...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2020.1774907

    authors: Köse HC,Yalçındağ N

    更新日期:2020-08-11 00:00:00

  • Association between Skin Thickness Measurements with Corneal Biomechanical Properties and Dry Eye Tests in Systemic Sclerosis.

    abstract::Purpose: To analyse the association between skin score with corneal biomechanics and dry eye tests in systemic sclerosis (SSc). Methods: 112 cases (limited SSc (lcSSc), n=50; diffuse SSc  (dcSSc), n=32; controls, n=30) were included in the study. Corneal hysteresis (CH), corneal resistance factor (CRF), Schirmer 1, 2 ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2018.1501496

    authors: Ayhan Z,Kaya M,Ozturk T,Arikan G,Birlik M

    更新日期:2019-01-01 00:00:00

  • Epidemic Retinitis with Macular Edema -Treatment Outcome with and without Steroids.

    abstract::Purpose: To study treatment outcomes with and without oral corticosteroids in epidemic retinitis (ER).Method: A retrospective, observational study of 35 eyes of 29 patients diagnosed as ER. Days taken for resolution of macular edema and retinitis lesions were compared in patients treated with oral antibiotics (Group 1...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2019.1704792

    authors: Kawali A,Srinivasan S,Mohan A,Bavaharan B,Mahendradas P,Shetty B

    更新日期:2020-01-21 00:00:00

  • Corneal Graft Rejection after Yellow Fever Vaccine: A Case Report.

    abstract::Purpose: To report an unusual case of corneal graft rejection after yellow fever vaccine. Methods: Case report. Results: We have described the case of a 48-year-old man who developed a corneal graft rejection in the left eye 3 weeks after a yellow fever vaccination. The ophthalmic examination of the left eye revealed ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2020.1870146

    authors: Vignapiano R,Vicchio L,Favuzza E,Cennamo M,Mencucci R

    更新日期:2021-01-28 00:00:00

  • Impact of Inflammation and Treatment on Self-reported Quality of Life in Patients with Non-acute Vogt-Koyanagi-Harada Disease (VKHD).

    abstract::Aims: To evaluate associations between vision-related (VR-) and health-related (HR-) QoL metrics and inflammation and treatment in non-acute VKHD patients.Methods: Cross-sectional study in a tertiary center in Sao Paulo, Brazil with 22 patients with non-acute VKHD followed prospectively for ≥12 months since acute dise...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2019.1668431

    authors: Souto FMS,Missaka RFBG,Magalhães BM,Caetano VMC,Takiuti JT,Lavezzo MM,Sakata VM,Oyamada MK,Hirata CE,Yamamoto JH

    更新日期:2019-10-31 00:00:00

  • A privileged view of NKT cells and peripheral tolerance through the eye.

    abstract::The eye is an immune-privileged site that uses specialized mechanisms to protect itself from damage and to preserve its visual acuity. Among the mechanisms that contribute to the eye's privileged existence is its ability to induce both local and peripheral tolerance to antigens that may transgress its chambers. Experi...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章,评审

    doi:10.1080/09273940490912371

    authors: Stein-Streilein J

    更新日期:2005-04-01 00:00:00

  • Subretinal Hemorrhage Complicating Retinal Angiomatous Proliferation in Tubercular Retinal Vasculitis.

    abstract:PURPOSE:To report a patient with submacular hemorrhage due to retinal angiomatous proliferation (RAP) in tubercular retinal vasculitis (TRV). METHODS:Case report. RESULTS:We report a 33-year-old Asian Indian patient of TRV presenting with capillary non-perfusion areas, submacular hemorrhage and venous loops. The pati...

    journal_title:Ocular immunology and inflammation

    pub_type: 信件

    doi:10.1080/09273948.2020.1803363

    authors: Agarwal A,Aggarwal K,Handa S,Markan A,Gupta V

    更新日期:2020-09-25 00:00:00

  • Branch retinal artery occlusion associated with Behçet disease.

    abstract:PURPOSE:To report 2 cases of branch retinal artery occlusion (BRAO) associated with Behçet disease (BD). DESIGN:Small case series. METHODS:Review of two patients' charts, fluorescein angiography, and optical coherence tomography (OCT). RESULTS:The authors report two young patients, diagnosed with BD, who developed d...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2011.582219

    authors: Yahia SB,Kahloun R,Jelliti B,Khairallah M

    更新日期:2011-08-01 00:00:00

  • Quantitative polymerase chain reaction for Mycobacterium tuberculosis in so-called Eales' disease.

    abstract:PURPOSE:To report mycobacterial load in the vitreous of patients labeled as having Eales' disease. METHODS:Eighty-eight patients were prospectively enrolled into 3 groups: 28 patients with so-called Eales' disease (group A); 30 positive controls with specific uveitis syndromes (group B), and 30 negative controls (grou...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2012.658134

    authors: Singh R,Toor P,Parchand S,Sharma K,Gupta V,Gupta A

    更新日期:2012-06-01 00:00:00

  • Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) - Report 2: Pattern of Uveitis Investigations in Singapore.

    abstract::Purpose: To analyze the pattern of laboratory investigations of uveitis at a tertiary referral eye care center in Singapore.Methods: Retrospective analysis of 2040 uveitis cases from the Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) database over a 12-year period (2004 - 2015).Results: Patients with...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2018.1535080

    authors: Low R,Chen EJ,Bin Ismail MA,Mi H,Ling HS,Lim WK,Teoh SC,Agrawal R

    更新日期:2020-01-01 00:00:00

  • Tachykinins as enhancers of prostaglandin E2-induced intraocular inflammation.

    abstract::The effects of tachykinins on prostaglandin E2 (PGE2)-induced intraocular inflammation were investigated. PGE2 (0.01% or 0.1%) instillation induced iridal hyperemia and protein leakage into the aqueous humor in rabbits, but caused minimal miosis. Intravitreally injected substance P (SP) or neurokinin A (NKA), on the o...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1076/ocii.6.1.19.8080

    authors: Tsuji F,Hamada M,Shirasawa E

    更新日期:1998-03-01 00:00:00

  • Antigen-presenting cells are targets of regulatory T cells similar to those that mediate anterior chamber-associated immune deviation.

    abstract:PURPOSE:To identify the means by which in-vitro-generated regulatory T cells, similar to those in anterior chamber-associated immune deviation (ACAID), suppress antigen-specific T-cell responses. METHODS:T regulators (T regs), generated by stimulating ovalbumin (OVA)-specific Tcr transgenic DO11.10 T cells with OVA-pu...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273940490895317

    authors: Yokoi H,Streilein JW

    更新日期:2004-06-01 00:00:00

  • Uveitis related to juvenile idiopathic arthritis: familial cases and possible genetic implication in the pathogenesis.

    abstract:PURPOSE:To describe four cases of familial Juvenile Idiopathic Arthritis (JIA) associated uveitis. DESIGN:Retrospective observational case series. METHODS:Clinical data from patients who present familial JIA-associated uveitis are described and possible genetic influence in disease etiology is reviewed. RESULTS:Two ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273941003678837

    authors: Julián K,Terrada C,Quartier P,Lehoang P,Bodaghi B

    更新日期:2010-06-01 00:00:00

  • Retinal Pigment Epithelium Tear after Immunosuppressive Treatment for Sarcoidosis-related Choroidal Granuloma.

    abstract:PURPOSE:To describe the formation of a retinal pigment epithelial (RPE) tear following immunosuppressive treatment of a large choroidal granuloma in a patient with sarcoidosis-related panuveitis. METHODS:A 25-year-old woman presented with bilateral sarcoidosis-related panuveitis and optic disc edema in both eyes with ...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2016.1180402

    authors: Knickelbein JE,Wei M,Nussenblatt RB,Sen HN

    更新日期:2017-12-01 00:00:00

  • Clinical Profile, Ultra-Wide-Field Fluorescence Angiography Findings, and Long-Term Prognosis of Uveitis in Tubulointerstitial Nephritis and Uveitis Syndrome at One Tertiary Medical Institute in China.

    abstract::Purpose: To analyze the clinical features and long-term prognosis of uveitis in tubulointerstitial nephritis and uveitis (TINU) syndrome in a cohort of Chinese patients. Methods: A total of 32 patients with TINU syndrome between 2000 - 2016 were analyzed retrospectively. Results: Mild anterior inflammation was observe...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2017.1394469

    authors: Yang M,Chi Y,Guo C,Huang J,Yang L,Yang L

    更新日期:2019-01-01 00:00:00

  • Evaluation of the Anterior Segment Parameters of the Patients with Scleroderma.

    abstract:PURPOSE:To evaluate corneal parameters of scleroderma (SC) patients by Pentacam-HR. METHODS:Twenty-two eyes of 22 SC patients and 33 eyes of 33 control subjects were enrolled. All participants underwent Pentacam (Pentacam-HR, Oculus, Germany) evaluation. Both SC and control groups were divided into two subgroups as dr...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.3109/09273948.2015.1115079

    authors: Şahin M,Yüksel H,Şahin A,Cingü AK,Türkcü FM,Kaya S,Yazmalar L,Batmaz İ

    更新日期:2017-04-01 00:00:00

  • Intravitreal Adalimumab for the Control of Breakthrough Intraocular Inflammation.

    abstract:PURPOSE:Investigate the efficacy of intravitreal adalimumab in breakthrough panuveitis in patients on systemic adalimumab for more than 3 months. METHODS:Retrospective study of patients on systemic adalimumab with breakthrough panuveitis requiring intravitreal adalimumab therapy. RESULTS:Seven eyes of four patients w...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2017.1335756

    authors: Kheir WJ,Mehanna CJ,Abdul Fattah M,Al Ghadban S,El Sabban M,Mansour AM,Hamam RN

    更新日期:2018-01-01 00:00:00

  • Patterns of Uveitis among Patients Attending Jimma University Department of Ophthalmology, Jimma, Ethiopia.

    abstract::Introduction: Uveitis is an important cause of blindness and ocular morbidity in the world. The patterns of uveitis have not been well characterized in sub-Saharan Africa. Purpose: To describe the characteristics of uveitis among patients presenting to Jimma University Department of Ophthalmology (JUDO) from July 2013...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2019.1644348

    authors: Tolesa K,Abateneh A,Kempen JH,Gelaw Y

    更新日期:2020-10-02 00:00:00

  • Neuro-Behcet Disease and Ocular Inflammation: A Case Report and Literature Review.

    abstract::Purpose: To describe a case of panuveitis with occlusive vasculitis leading to the diagnosis of neuro-Behcet disease (NBD) and discuss the relationship between uveitis and NBD. Methods: Case report with a literature review of ocular inflammation in NBD. Results: A 26-year-old woman with a seven-month history of recurr...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2020.1787461

    authors: Patel SA,Okeagu C,Jones K,Chaudhry A,Berkenstock MK

    更新日期:2020-08-19 00:00:00

  • Idiopathic Central Nervous System Inflammatory Disease in the Setting of HLA-B27 Uveitis.

    abstract::Purpose: The purpose of the article is to describe a novel case of idiopathic central nervous system inflammatory disease with bilateral human leukocyte antigen (HLA)-B27-positive anterior uveitis. Methods/Results: A 15-year-old African American boy with bilateral HLA-B27-positive anterior uveitis controlled with topi...

    journal_title:Ocular immunology and inflammation

    pub_type: 杂志文章

    doi:10.1080/09273948.2018.1449865

    authors: Crowell EL,Pfeiffer ML,Kamdar AA,Koenig MK,Wittenberg SE,Supsupin EP,Adesina OO

    更新日期:2019-01-01 00:00:00