Syd/JIP3 controls tissue size by regulating Diap1 protein turnover downstream of Yorkie/YAP.

abstract：:The acquisition of fertilizability in coelomic eggs of Xenopus laevis has been shown to be correlated with the physical, biochemical, and ultrastructural alterations of the egg envelope [coelomic envelope (CE)] induced during the passage of eggs through the pars recta portion of the oviduct. However, no direct evidenc...

journal_title：Developmental biology

authors： Katagiri C,Yoshizaki N,Kotani M,Kubo H

更新日期：1999-06-15 00:00:00

abstract：:teashirt (tsh) encodes a zinc-finger protein that is thought to be part of a network that contributes to regionalization of the Drosophila embryo and establishes the domains of Hox protein function. tsh and the Hox gene Sex combs reduced (Scr) are essential to establish the identity of the first thoracic segment. We u...

journal_title：Developmental biology

authors： Taghli-Lamallem O,Gallet A,Leroy F,Malapert P,Vola C,Kerridge S,Fasano L

更新日期：2007-07-01 00:00:00

abstract：:The embryonic cell lineage of Caenorhabditis elegans has been traced from zygote to newly hatched larva, with the result that the entire cell lineage of this organism is now known. During embryogenesis 671 cells are generated; in the hermaphrodite 113 of these (in the male 111) undergo programmed death and the remaind...

journal_title：Developmental biology

authors： Sulston JE,Schierenberg E,White JG,Thomson JN

更新日期：1983-11-01 00:00:00

abstract：:The mesoderm of the sea urchin embryo conventionally is divided into two populations of cells; the primary mesenchyme cells (PMCs), which produce the larval skeleton, and the secondary mesenchyme cells (SMCs), which differentiate into a variety of cell types but do not participate in skeletogenesis. In this study we e...

journal_title：Developmental biology

authors： Ettensohn CA,McClay DR

更新日期：1988-02-01 00:00:00

abstract：:The processes of myelination remain incompletely understood but are of profound biomedical importance owing to the several dysmyelinating and demyelinating disorders known in humans. Here, we analyze the zebrafish puma mutant, isolated originally for pigment pattern defects limited to the adult stage. We show that pum...

journal_title：Developmental biology

authors： Larson TA,Gordon TN,Lau HE,Parichy DM

更新日期：2010-10-15 00:00:00

abstract：:The colonial tunicate Botrylloides leachi can regenerate functional adults from minute vasculature fragments, in a poorly understood phenomenon termed Whole Body Regeneration (WBR). Using Piwi expression (Bl-Piwi), blood cell labeling and electron microscopy, we show that WBR develops through activation, mobilization ...

journal_title：Developmental biology

authors： Rinkevich Y,Rosner A,Rabinowitz C,Lapidot Z,Moiseeva E,Rinkevich B

更新日期：2010-09-01 00:00:00

abstract：:Developmental pattern formation allows cells within a tissue or organ to coordinate their development and establish cell types in relationship to one another. To better characterize the developmental patterning events within one organ, the C. elegans hindgut, we have analyzed the expression pattern of several genes us...

journal_title：Developmental biology

authors： Sewell ST,Zhang G,Uttam A,Chamberlin HM

更新日期：2003-10-01 00:00:00

abstract：:Nonmuscle myosin-II is a key motor protein that drives cell shape change and cell movement. Here, we analyze the function of nonmuscle myosin-II during Drosophila embryonic myogenesis. We find that nonmuscle myosin-II and the adhesion molecule, PS2 integrin, colocalize at the developing muscle termini. In the paradigm...

journal_title：Developmental biology

authors： Bloor JW,Kiehart DP

更新日期：2001-11-15 00:00:00

abstract：:We describe the lineage and morphogenesis of neural plate cells in the ascidian, Ciona intestinalis, from reconstructed cell maps of embryos at 12-min intervals during and after neurulation, between 31 and 61% of embryonic development. Neurulation commences in a posterior to anterior wave following in the wake of the ...

journal_title：Developmental biology

authors： Nicol D,Meinertzhagen IA

更新日期：1988-12-01 00:00:00

abstract：:A population of hematopoietic progenitors becomes committed within the embryo proper in the floor of the aorta (P-Sp/AGM in the mouse). In birds, this first aspect of intraembryonic hematopoiesis is prominent during embryonic day 3 (E3) as endothelium-associated "intra-aortic clusters." Between E6 and E8, diffuse hema...

journal_title：Developmental biology

authors： Jaffredo T,Gautier R,Brajeul V,Dieterlen-Lièvre F

更新日期：2000-08-15 00:00:00

abstract：:The fate of bacteriophage lambda-DNA was examined after injection into the fertilized eggs of Xenopus laevis. Injection of a large amount of lambda-DNA (ca. 24 ng) into a fertilized Xenopus egg induced the formation around the injected DNA of a giant nucleus-like structure which was surrounded by an apparently normal ...

journal_title：Developmental biology

authors： Shiokawa K,Sameshima M,Tashiro K,Miura T,Nakakura N,Yamana K

更新日期：1986-08-01 00:00:00

abstract：:This study describes the temporal pattern of posterior positional identity in mouse limb bud cells. To do this wedges of tissue from the posterior edge of mouse limb buds at various stages (limb stages: Wanek et al., 1989b. J. Exp. Zool. 249, 41-49) were grafted to the anterior edge of a host chick embryo wing bud. Gr...

journal_title：Developmental biology

authors： Wanek N,Bryant SV

更新日期：1991-10-01 00:00:00

abstract：:Chordin is the prototype of a group of cysteine-rich domain-containing proteins that bind and modulate signaling of various TGFbeta-like ligands. Chordin-like 1 and 2 (CHL1 and 2) are two members of this group that have been described in human, mouse, and chick. However, in vivo roles for CHL1 and 2 in early developme...

journal_title：Developmental biology

authors： Branam AM,Hoffman GG,Pelegri F,Greenspan DS

更新日期：2010-05-15 00:00:00

abstract：:Monoclonal antibodies (mAbs), electrophoresis, immunoblotting, and immunohistochemistry were used to determine the molecular properties of cardiac myosin heavy chain (MHC) isoforms and the regions of the developing chicken heart in which they were expressed. Adult atria expressed three electrophoretically distinct MHC...

journal_title：Developmental biology

authors： Evans D,Miller JB,Stockdale FE

更新日期：1988-06-01 00:00:00

abstract：:We report here the identification and characterization of a novel gene, T1 alpha, expressed in high abundance in adult rat lung, fetal lung, and early fetal brain. T1 alpha was identified by a monoclonal antibody previously shown to be specific for an antigen expressed by alveolar epithelial type I cells. The cDNA for...

journal_title：Developmental biology

authors： Rishi AK,Joyce-Brady M,Fisher J,Dobbs LG,Floros J,VanderSpek J,Brody JS,Williams MC

更新日期：1995-01-01 00:00:00

abstract：:DSL (Delta, Serrate, Lag-2) ligands activate Notch signaling and thereby regulate the differentiation of many different cell types during development. We have isolated a novel Serrate-like gene, Jagged2, whose amino acid sequence and expression pattern during rat embryogenesis suggest that it functions as a ligand for...

journal_title：Developmental biology

authors： Shawber C,Boulter J,Lindsell CE,Weinmaster G

更新日期：1996-11-25 00:00:00

abstract：:Neuronal circuit development and function require proper synapse formation and maintenance. Genetic screens are one powerful method to identify the mechanisms shaping synaptic development and stability. However, genes with essential roles in non-neural tissues may be missed in traditional loss-of-function screens. In ...

journal_title：Developmental biology

authors： Valakh V,Naylor SA,Berns DS,DiAntonio A

更新日期：2012-06-15 00:00:00

abstract：:How natural variation in embryo size affects patterning of the Drosophila embryo dorsal-ventral (DV) axis is not known. Here we examined quantitatively the relationship between nuclear distribution of the Dorsal transcription factor, boundary positions for several target genes, and DV axis length. Data were obtained f...

journal_title：Developmental biology

authors： Garcia M,Nahmad M,Reeves GT,Stathopoulos A

更新日期：2013-09-01 00:00:00

abstract：:We have investigated the accumulation and adenylation of the maternal mRNA during oogenesis in the oocytes of the marine worm Urechis caupo. The analysis, using in vitro translation and cDNA probes to assay for specific mRNAs, demonstrates that different maternal mRNAs accumulate with different patterns during oogenes...

journal_title：Developmental biology

authors： Rosenthal ET,Wilt FH

更新日期：1986-09-01 00:00:00

abstract：:The relative transcription of three unlinked actin genes of the sea urchin Strongylocentrotus purpuratus was measured in isolated nuclei, at several stages during embryonic development. Transcription of two cytoskeletal actin genes, CyI and CyIIIa, was first detected in 64-128 cell embryos. At the early stages, the Cy...

journal_title：Developmental biology

authors： Hickey RJ,Boshar MF,Crain WR Jr

更新日期：1987-11-01 00:00:00

abstract：:The ability of Xenopus oocytes to undergo insulin- or insulin-like growth factor 1-induced meiotic maturation develops during oogenesis, with cells 1.0 mm in diameter or larger responding in a size-dependent manner. Since insulin-induced oocyte maturation was shown previously to be p21 ras-dependent, experiments were ...

journal_title：Developmental biology

authors： Davis D,Sadler SE

更新日期：1992-01-01 00:00:00

abstract：:Mutations in the NF1 gene may cause developmental abnormalities and the formation of a variety of tumors of neural crest origin in humans. The NF1 gene codes for a large protein, neurofibromin (nf), which is structurally and functionally related to yeast and human ras-GTPase-activating proteins (ras-GAPs). Recently, t...

journal_title：Developmental biology

authors： Huynh DP,Nechiporuk T,Pulst SM

更新日期：1994-02-01 00:00:00

abstract：:Glycosaminoglycans in the form of heparan sulfate proteoglycans (HSPG) and chondroitin sulfate proteoglycans (CSPG) are required for normal kidney organogenesis. The specific roles of HSPGs and CSPGs on ureteric bud (UB) branching morphogenesis are unclear, and past reports have obtained differing results. Here we emp...

journal_title：Developmental biology

authors： Steer DL,Shah MM,Bush KT,Stuart RO,Sampogna RV,Meyer TN,Schwesinger C,Bai X,Esko JD,Nigam SK

更新日期：2004-08-15 00:00:00

abstract：:We have investigated oocyte development in Hydra vulgaris, a member of one of the oldest metazoan phyla. We show that oocyte determination involves a mechanism that establishes a subset of precursor interstitial cells competent to differentiate into oocytes. The oocyte is singled out from this subset and the competenc...

journal_title：Developmental biology

authors： Miller MA,Technau U,Smith KM,Steele RE

更新日期：2000-08-15 00:00:00

abstract：:Symplastic spermatids (sys) male mice are sterile due to a recessive mutation that causes defective adhesion between spermatids and Sertoli cells within the seminiferous epithelium. We show that the mutation in sys mice involves a deletion of 1.24 Mb of chromosome 14. Comparative genomic analysis suggests that this re...

journal_title：Developmental biology

authors： Obholz KL,Akopyan A,Waymire KG,MacGregor GR

更新日期：2006-10-15 00:00:00

abstract：:Cell signaling pathways, such as Wnt, Hedgehog (Hh), Notch, and Hippo, are essential for embryogenesis, organogenesis, and tissue homeostasis. In this study, we analyzed 415 genes involved in these pathways in the allotetraploid frog, Xenopus laevis. Most genes are retained in two subgenomes called L and S (193 homeol...

journal_title：Developmental biology

authors： Michiue T,Yamamoto T,Yasuoka Y,Goto T,Ikeda T,Nagura K,Nakayama T,Taira M,Kinoshita T

更新日期：2017-06-15 00:00:00

abstract：:Nociceptive neurons innervate the skin with complex dendritic arbors that respond to pain-evoking stimuli such as harsh mechanical force or extreme temperatures. Here we describe the structure and development of a model nociceptor, the PVD neuron of C. elegans, and identify transcription factors that control morphogen...

journal_title：Developmental biology

authors： Smith CJ,Watson JD,Spencer WC,O'Brien T,Cha B,Albeg A,Treinin M,Miller DM 3rd

更新日期：2010-09-01 00:00:00

abstract：:During endochondral ossification, the differentiation of proliferating into hypertrophic chondrocytes is a key step determining the pace of bone formation and the future length of the skeletal elements. A variety of transcription factors are expressed at the onset of hypertrophy coordinating the expression of differen...

journal_title：Developmental biology

authors： Wuelling M,Schneider S,Schröther VA,Waterkamp C,Hoffmann D,Vortkamp A

更新日期：2020-01-01 00:00:00

abstract：:Two main processes are involved in driving ventral mesendoderm internalization in the Xenopus gastrula. First, vegetal rotation, an active movement of the vegetal cell mass, initiates gastrulation by rolling the peripheral blastocoel floor against the blastocoel roof. In this way, the leading edge of the internalized ...

journal_title：Developmental biology

authors： Ibrahim H,Winklbauer R

更新日期：2001-12-01 00:00:00

abstract：:Morphogenesis of the vertebrate head relies on proper dorsal-ventral (D-V) patterning of neural crest cells (NCC) within the pharyngeal arches. Endothelin-1 (Edn1)-induced signaling through the endothelin-A receptor (Ednra) is crucial for cranial NCC patterning within the mandibular portion of the first pharyngeal arc...

journal_title：Developmental biology

authors： Tavares AL,Garcia EL,Kuhn K,Woods CM,Williams T,Clouthier DE

更新日期：2012-11-01 00:00:00