Protein kinase C mediated intracellular signaling pathways are involved in the regulation of sodium-dependent glucose co-transporter SGLT1 activity.

abstract：:The presented results show for the first time that the neurogenic transdifferentiation of hUC-MSCs considerably changes the elements of purinergic signaling profile. Although, it has been demonstrated in the literature that extracellular nucleotides and nucleosides determine the fate of mesenchymal and neural stem cel...

journal_title：Journal of cellular biochemistry

authors： Czarnecka J,Porowińska D,Bajek A,Hołysz M,Roszek K

更新日期：2017-03-01 00:00:00

abstract：:MUC4, a transmembrane glycoprotein, interferes with cell adhesion, and promotes EGFR signaling in cancer. Studies in rat models have demonstrated steroid hormonal regulation of endometrial MUC4 expression. In this study, qRT-PCR screening of mouse tissues determined that Muc4 mRNA also was robustly expressed in mouse ...

journal_title：Journal of cellular biochemistry

authors： Chapela PJ,Broaddus RR,Hawkins SM,Lessey BA,Carson DD

更新日期：2015-11-01 00:00:00

abstract：:It has been proposed carbon tetrachloride (CCl4 ) intoxication due to the production of free radicals and serum levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP) overload results hepatotoxicity. Phosphatidylserine (PS) has shown antioxidant activity in numerous ...

journal_title：Journal of cellular biochemistry

authors： Yousefi-Manesh H,Shirooie S,Partoazar A,Nikoui V,Estakhri MRA,Bakhtiarian A

更新日期：2019-02-15 00:00:00

abstract：BACKGROUND:Cholangiocarcinoma (CC) is devastating neoplasm and very few specific biomarkers could be used in clinical diagnosis. A study was taken to find novel serum biomarkers for CC. METHODS:Surface enhanced laser desorption/ionization (SELDI) technology was used to analyze 427 serum samples including 56 CCs, 49 he...

journal_title：Journal of cellular biochemistry

authors： Liu L,Wang J,Liu B,Dai S,Wang X,Chen J,Huang L,Xiao X,He D

更新日期：2008-06-01 00:00:00

abstract：:Burkitt lymphoma (BL) commonly exhibits Epstein-Barr virus (EBV) positivity associated with latent chronic infection. Models of acute EBV infection have been associated with cellular resistance to apoptosis. However, the effect of latent long-term EBV infection on apoptosis induced by drugs is not well defined. To det...

journal_title：Journal of cellular biochemistry

authors： Lima RT,Seca H,Soares P,Nascimento MS,Vasconcelos MH

更新日期：2011-01-01 00:00:00

abstract：:In the present study, monoclonal antibodies were produced using porcine adipocyte extracts as the immunogen. Two of the monoclonal antibodies, designated CB6 and IB4, exhibited reactivity toward only cells containing lipid in stromal-vascular cell cultures. The antigens recognized by the CB6 and IB4 monoclonal antibod...

journal_title：Journal of cellular biochemistry

authors： Wright JT,Hausman GJ

更新日期：1991-03-01 00:00:00

abstract：:The caspase family of protease is speculated to have a crucial role in apoptosis. The effect of treatment with Idarubicin (IDA) and Medroxyprogesterone acetate (MPA), used alone or in combination, on the activation of Caspase-3 in canine Chronic Lymphatic Leukaemia (CLL) cells was investigated, in order to clarify the...

journal_title：Journal of cellular biochemistry

authors： Florio S,Crispino L,Ciarcia R,Vacca G,Pagnini U,de Matteis A,Pacilio C,D'Andrilli G,Kumar C,Giordano A

更新日期：2003-07-01 00:00:00

abstract：:The aim of the present study was to test the hypothesis that the decreased renal tubular reabsorption of calcium observed in estrogen deficiency is associated with a local regulation of either PTHrP or PTH/PTHrP receptor genes in the kidney. Rats were randomly sham-operated (S) or ovariectomized receiving either vehic...

journal_title：Journal of cellular biochemistry

authors： Cros M,Silve C,Graulet AM,Morieux C,Ureña P,de Vernejoul MC,Bouizar Z

更新日期：1998-07-01 00:00:00

abstract：:Prostate cancer (PCa) cells frequently invade the surrounding stroma, leading to heterogeneous formation of structural atypia. The surrounding stroma contains multiple functionally diverse populations of fibroblasts that trigger numerous changes in PCa cells including motility. Thus, we hypothesized that direct or ind...

journal_title：Journal of cellular biochemistry

authors： Ishii K,Nakagawa Y,Matsuda C,Katoh D,Ichishi M,Shirai T,Hirokawa Y,Fujiwara M,Sugimura Y,Watanabe M

更新日期：2021-01-22 00:00:00

abstract：:Poor prognosis and low survival are commonly seen in patients with glioblastoma multiforme (GBM). Due to the specific nature of solid tumors such as GBM, delivery of therapeutic agents to the tumor sites is difficult. So, one of the major challenges in the treatment of these tumors is a selection of appropriate method...

journal_title：Journal of cellular biochemistry

authors： Jabbarpour Z,Kiani J,Keshtkar S,Saidijam M,Ghahremani MH,Ahmadbeigi N

更新日期：2020-02-01 00:00:00

abstract：:Lysophosphatidic acid (LPA) elicits diverse cellular responses through cell surface LPA receptors in nervous system-derived cells and cell lines. The developing nervous system is one of the major loci for LPA receptor expression. Recent studies have also revealed that metabolic pathways of LPA are present in the nervo...

journal_title：Journal of cellular biochemistry

authors： Fukushima N

更新日期：2004-08-01 00:00:00

abstract：:Hepassocin (HPS) is a specific mitogenic active factor for hepatocytes, and inhibits growth by overexpression in hepatocellular carcinoma (HCC) cells. However, the mechanism of HPS regulation on growth of liver-derived cells still remains largely unknown. In this study, we found that HPS was expressed and secreted int...

journal_title：Journal of cellular biochemistry

authors： Cao MM,Xu WX,Li CY,Cao CZ,Wang ZD,Yao JW,Yu M,Zhan YQ,Wang XH,Tang LJ,Chen H,Li W,Ge CH,Yang XM

更新日期：2011-10-01 00:00:00

abstract：UNLABELLED:Chemotherapy treatment is the standard in triple negative breast cancers, a cancer subgroup which lacks a specific target. The mechanisms leading to the response, as well as any markers that allow the differentiation between responder and non-responder groups prior to treatment are unknown. In parallel, miRN...

journal_title：Journal of cellular biochemistry

authors： Tormo E,Pineda B,Serna E,Guijarro A,Ribas G,Fores J,Chirivella E,Climent J,Lluch A,Eroles P

更新日期：2015-09-01 00:00:00

abstract：:In this study, we purpose to investigate a novel five-gene signature for predicting the prognosis of patients with laryngeal cancer. The laryngeal cancer datasets were obtained from The Cancer Genome Atlas (TCGA). Both univariate and multivariate Cox regression analysis was applied to screening for prognostic differen...

journal_title：Journal of cellular biochemistry

authors： Zhang G,Fan E,Yue G,Zhong Q,Shuai Y,Wu M,Feng G,Chen Q,Gou X

更新日期：2019-10-31 00:00:00

abstract：:Survivin is recognized as an attractive target in cancer therapy because of its selective overexpression in the majority of tumors. Upregulated expression of this protein correlates with increased tumor grade, recurrence risk and decreased cancer patients survival. In this study, we assessed the efficacy of two surviv...

journal_title：Journal of cellular biochemistry

authors： Croci DO,Cogno IS,Vittar NB,Salvatierra E,Trajtenberg F,Podhajcer OL,Osinaga E,Rabinovich GA,Rivarola VA

更新日期：2008-10-01 00:00:00

abstract：:DNA methylation plays a role in the etiology of primary breast cancers. We analyzed paired primary and second breast tumors to elucidate the role of methylation in recurrence. Methylation profiles from paired primary and second breast tumors of 23 women were assessed using the HumanMethylation450 BeadChip. Twelve wome...

journal_title：Journal of cellular biochemistry

authors： Williams KE,Jawale RM,Schneider SS,Otis CN,Pentecost BT,Arcaro KF

更新日期：2019-01-01 00:00:00

abstract：:Preserving self-renewal, multipotent capacity, and large-scale expansion of highly functional progenitor cells, including endothelial progenitor cells (EPCs), is a controversial issue. These current limitations, therefore, raise the need of developing promising in vitro conditions for prolonged expansion of EPCs witho...

journal_title：Journal of cellular biochemistry

authors： Siavashi V,Nassiri SM,Rahbarghazi R,Vafaei R,Sariri R

更新日期：2016-08-01 00:00:00

abstract：:Self-renewal and differentiation of hematopoietic stem and progenitor cells are defined by the ensembles of genes expressed by these cells. Here we report identification of a novel gene named Jedi, which is expressed predominantly in short- and long-term repopulating stem cells when compared to more mature bone marrow...

journal_title：Journal of cellular biochemistry

authors： Krivtsov AV,Rozov FN,Zinovyeva MV,Hendrikx PJ,Jiang Y,Visser JW,Belyavsky AV

更新日期：2007-06-01 00:00:00

abstract：:The BRCA1 tumor suppressor involved in breast and ovarian cancer is linked to several fundamental cell regulatory processes. Recently, it was reported that BRCA1 supports localization of XIST RNA to the inactive X chromosome (Xi) in women. The apparent cytological overlap between BRCA1 and XIST RNA across the Xi raise...

journal_title：Journal of cellular biochemistry

authors： Pageau GJ,Hall LL,Lawrence JB

更新日期：2007-03-01 00:00:00

abstract：:We examined the action of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) on HeLa cells and compared it with that of cisplatin (CP). MNNG directly killed a substantial number of cells within 1 hour and resulted in strong DNA-damage as evidenced by Comet measurements. Despite appearance of DNA lesions, p53 protein was not ...

journal_title：Journal of cellular biochemistry

authors： Wesierska-Gadek J,Gueorguieva M,Schloffer D,Uhl M,Wojciechowski J

更新日期：2003-08-15 00:00:00

abstract：:Membrane type 1 matrix metalloproteinase (MT1-MMP, MMP14) is an efficient extracellular matrix (ECM) degrading enzyme that plays important roles in tissue homeostasis and cell invasion. Like a number of type I membrane proteins, MT1-MMP can be internalized from the cell surface through early and recycling endosomes to...

journal_title：Journal of cellular biochemistry

authors： Hakulinen J,Sankkila L,Sugiyama N,Lehti K,Keski-Oja J

更新日期：2008-12-01 00:00:00

abstract：:Expression of cyclin, a non-histone nuclear protein, during recombinant interleukin 2 (rIL2)-driven cell-cycle progression of cloned T lymphocytes has been assessed. We found that expression of cyclin protein, as detected by immunofluorescence, is tightly associated with proliferation, and not merely S-phase, of L2 ce...

journal_title：Journal of cellular biochemistry

authors： Shipman PM,Sabath DE,Fischer AH,Comber PG,Sullivan K,Tan EM,Prystowsky MB

更新日期：1988-11-01 00:00:00

abstract：:We have examined the effect of calcium-dependent adhesion, mediated by N-cadherin, on cell signaling during chondrogenesis of multipotential embryonic mouse C3H10T1/2 cells. The activity of chondrogenic genes, type II collagen, aggrecan, and Sox9 were examined in monolayer (non-chondrogenic), and micromass (chondrogen...

journal_title：Journal of cellular biochemistry

authors： Modarresi R,Lafond T,Roman-Blas JA,Danielson KG,Tuan RS,Seghatoleslami MR

更新日期：2005-05-01 00:00:00

abstract：:Fracture repair is a complex process involving timed cellular recruitment, gene expression, and synthesis of compounds that regenerate native tissue to restore the mechanical integrity, and thus function of injured bone. While the majority of fractures heal without complication, this takes time and a subset of patient...

journal_title：Journal of cellular biochemistry

authors： Komatsu DE,Warden SJ

更新日期：2010-02-01 00:00:00

abstract：:The human P zero-related protein (hPZR) has a unique function in regulating cell migration. This activity is dependent on both its cytoplasmic immunoreceptor tyrosine inhibitory motif (ITIM) and its interaction with the tyrosine protein phosphatase, src homology phosphatase-2 (SHP-2). Here, using in silico and cDNA cl...

journal_title：Journal of cellular biochemistry

authors： Roubelakis MG,Martin-Rendon E,Tsaknakis G,Stavropoulos A,Watt SM

更新日期：2007-11-01 00:00:00

abstract：:Two monoclonal antibodies that cause changes in the morphology of cultured myogenic cells are described. Antibody JG9 causes myoblasts to round up and causes myotubes to become thin, cable-like structures with multiple round swellings. Antibody JG22 causes both myoblasts and myotubes to become round refractile cells p...

journal_title：Journal of cellular biochemistry

authors： Greve JM,Gottlieb DI

更新日期：1982-01-01 00:00:00

abstract：:We explored the effect of S100A12 gene on serum levels of anti-inflammatory/pro-inflammatory cytokines in septic rats by activating the extracellular signal-regulated kinase (ERK) signaling pathway. A total of 180 specific pathogen-free (SPF) rats were purchased to establish cecal ligation and puncture (CLP) model. Ra...

journal_title：Journal of cellular biochemistry

authors： Wen X,Han XR,Wang YJ,Fan SH,Zhang ZF,Wu DM,Lu J,Zheng YL

更新日期：2018-05-01 00:00:00

abstract：:A large number of natural compounds, such as phenolic compounds, have been scientifically evaluated in the search for enzyme inhibitors. The interactions between the phenolic compound p-coumaric acid and the enzymes present in snake venoms (used as research tools) were evaluated in vitro and in silico. The p-coumaric ...

journal_title：Journal of cellular biochemistry

authors： Cesar PHS,Cardoso Trento MV,Sales TA,Marques TR,Braga MA,Ramalho TC,Marcussi S

更新日期：2019-09-01 00:00:00

abstract：:The specific lysis of bloodstream trypanosomes by serum from a nonpermissive mammalian host is the result of interaction between the serum trypanocidal factor (high-density lipoprotein) and the trypanosome surface. The studies described in this paper attempt to define further the mode of action of this cytotoxic lipop...

journal_title：Journal of cellular biochemistry

authors： Rifkin MR

更新日期：1983-01-01 00:00:00

abstract：:Epithelial-to-mesenchymal transition (EMT) is a major process to regulate cell migration and invasion. Inhibition of epidermal growth factor receptor (EGFR)-mediated EMT by tyrosine kinase inhibitors (TKIs) is a strategy to prevent lung cancer invasion. However, drug resistance is emerged and accelerated invasion thro...

journal_title：Journal of cellular biochemistry

authors： Hsieh YS,Liao CH,Chen WS,Pai JT,Weng MS

更新日期：2017-12-01 00:00:00