Environmental and economic impact of using increased fresh gas flow to reduce carbon dioxide absorbent consumption in the absence of inhalational anaesthetics.

Abstract:

BACKGROUND:Increasing fresh gas flow (FGF) to a circle breathing system reduces carbon dioxide (CO2) absorbent consumption. We assessed the environmental and economic impacts of this trade-off between gas flow and absorbent consumption when no inhalational anaesthetic agent is used. METHODS:A test lung with fixed CO2 inflow was ventilated via a circle breathing system of an anaesthetic machine (Dräger Primus or GE Aisys CS2) using an FGF of 1, 2, 4, or 6 L min-1. We recorded the time to exhaustion of the CO2 absorbent canister, defined as when inspired partial pressure of CO2 exceeded 0.3 kPa. For each FGF, we calculated the economic costs and the environmental impact associated with the manufacture of the CO2 absorbent canister and the supply of medical air and oxygen. Environmental impact was measured in 100 yr global-warming potential, analysed using a life cycle assessment 'cradle to grave' approach. RESULTS:Increasing FGF from 1 to 6 L min-1 was associated with up to 93% reduction in the combined running cost with minimal net change to the 100 yr global-warming potential. Most of the reduction in cost occurred between 4 and 6 L min-1. Removing the CO2 absorbent from the circle system, and further increasing FGF to control CO2 rebreathing, afforded minimal further economic benefit, but more than doubled the global-warming potential. CONCLUSIONS:In the absence of inhalational anaesthetic agents, increasing FGF to 6 L min-1 reduces running cost compared with lower FGFs, with minimal impact to the environment.

journal_name

Br J Anaesth

authors

Zhong G,Abbas A,Jones J,Kong S,McCulloch T

doi

10.1016/j.bja.2020.07.043

subject

Has Abstract

pub_date

2020-11-01 00:00:00

pages

773-778

issue

5

eissn

0007-0912

issn

1471-6771

pii

S0007-0912(20)30634-6

journal_volume

125

pub_type

杂志文章
  • Effect of diazepam on pancuronium-induced neuromuscular blockade maintained by a feedback system.

    abstract::The possibility of an interaction between diazepam and pancuronium bromide was investigated in six patients undergoing general anaesthesia maintained with fentanyl, droperidol and nitrous oxide. Neuromuscular blockade was controlled using a feedback mechanism which automatically adjusted the rate of injection of pancu...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/53.8.859

    authors: Asbury AJ,Henderson PD,Brown BH,Turner DJ,Linkens DA

    更新日期:1981-08-01 00:00:00

  • Prediction of inspired oxygen concentration within a circle anaesthetic system.

    abstract::Fresh gas flows of nitrous oxide, oxygen and halothane at 6, 3, 2 and 1 litre/min were introduced into a circle absorber system. Spontaneous respiration and IPPV were studied and a regression of inspired on delivered oxygen concentration % was calculated. The difference between delivered and inspired oxygen concentrat...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/48.3.217

    authors: Raymond JA

    更新日期:1976-03-01 00:00:00

  • Third-generation FloTrac/Vigileo does not reliably track changes in cardiac output induced by norepinephrine in critically ill patients.

    abstract:BACKGROUND:The ability of the third-generation FloTrac/Vigileo software to track changes in cardiac index (CI) induced by volume expansion and norepinephrine in critically ill patients is unknown. METHODS:In subjects with circulatory failure, we administered volume expansion (20 subjects) and increased (20 subjects) o...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aer491

    authors: Monnet X,Anguel N,Jozwiak M,Richard C,Teboul JL

    更新日期:2012-04-01 00:00:00

  • Malignant hyperpyrexia and sudden infant death syndrome.

    abstract::This paper reports three investigations of the suggested relationship between sudden infant death syndrome (SIDS) and malignant hyperpyrexia (MH). In the first study 151 MH-susceptible families completed a questionnaire designed to identify the incidence of SIDS within their own pedigree. In the second study 106 SIDS ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/60.1.28

    authors: Ellis FR,Halsall PJ,Harriman DG

    更新日期:1988-01-01 00:00:00

  • Metoclopramide in the prevention of postoperative nausea and vomiting: a quantitative systematic review of randomized, placebo-controlled studies.

    abstract::Metoclopramide has been used for almost 40 yr to prevent postoperative nausea and vomiting (PONV). We have reviewed the efficacy and safety of metoclopramide for the prevention of PONV. A systematic search (MEDLINE, EMBASE, manufacturers' databases, hand searching, bibliographies, all languages, up to June 1998) was p...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,meta分析

    doi:10.1093/bja/83.5.761

    authors: Henzi I,Walder B,Tramèr MR

    更新日期:1999-11-01 00:00:00

  • Effect of low and high concentrations of alfentanil administered intrathecally on A delta and C fibre mediated somatosympathetic reflexes.

    abstract::We have studied the effects of alfentanil administered intrathecally on somatosympathetic reflexes evoked by stimulation of radial and tibial nerves in 10 anaesthetized and paralysed dogs. In five animals, alfentanil was administered in doses of 100, 100, 200 and 400 micrograms in 0.8 ml and 800 micrograms in 1.6 ml p...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/68.5.503

    authors: Wang C,Chakrabarti MK,Whitwam JG

    更新日期:1992-05-01 00:00:00

  • Extradural block in patients who have previously undergone caesarean section.

    abstract::The 119 patients who had undergone previous Caesarean section lumbar extradural block was administered to 77 (65%); the other 42 (35%) received analgesia with ketobemidone 0.8-1.0 ml i.m. or nitrous oxide in oxygen intermittently, or both. Controlled i.v. infusion of oxytocin for induction or acceleration of labour wa...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/52.8.827

    authors: Carlsson C,Nybell-Lindahl G,Ingemarsson I

    更新日期:1980-08-01 00:00:00

  • Studies of the neuromuscular blocking effects of BW 403C65 in frog and cat muscle.

    abstract::BW 403C65, an isoquinolinium bisquaternary compound, was investigated for its neuromuscular blocking properties. In vitro in from preparations, low concentrations induced an increase in miniature endplate potentials (m.e.p.p.) frequency without altering their amplitude. With increasing concentrations m.e.p.p. frequenc...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/47.9.929

    authors: Post EL,Sokoll MD,Gergis SD,Dretchen KL,Cronnelly R

    更新日期:1975-09-01 00:00:00

  • Effect of pre- vs postoperative inguinal field block on postoperative pain after herniorrhaphy.

    abstract::The analgesic effects of an identical inguinal field block, performed before or immediately after inguinal herniorrhaphy, were evaluated in 32 healthy patients in a double-blind, randomized study. During surgery, all patients received a light general anaesthesia with thiopentone, alfentanil and nitrous oxide in oxygen...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/68.4.344

    authors: Dierking GW,Dahl JB,Kanstrup J,Dahl A,Kehlet H

    更新日期:1992-04-01 00:00:00

  • Observations on extradural morphine analgesia in various pain conditions.

    abstract::We report the extradural administration of low-dose morphine in 10 ml of 10% dextrose (2-3 mg) to 98 adult patients with various types of acute and chronic pain. Extradural morphine injections were given either via a Tuohy needle (single or repeat injection) or via an extradural catheter. Pain relief was evaluated by ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/52.3.247

    authors: Magora F,Olshwang D,Eimerl D,Shorr J,Katzenelson R,Cotev S,Davidson JT

    更新日期:1980-03-01 00:00:00

  • Effect of pretreatment with oral pyridostigmine on subsequent activity of alcuronium in non-anaesthetized subjects.

    abstract::We have studied the effects of alcuronium in 10 healthy, non-anaesthetized volunteers after they had been taking oral pyridostigmine 30 mg 8 hourly. The responses of adductor pollicis were recorded using an isolated forearm procedure (IFP) during onset and recovery of neuromuscular block produced by 1.5 mg of relaxant...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/66.3.365

    authors: Turner GA,Williams JD,Baker DJ

    更新日期:1991-03-01 00:00:00

  • Efficacy of low-dose bupivacaine in spinal anaesthesia for Caesarean delivery: systematic review and meta-analysis.

    abstract::Spinal anaesthesia is the preferred anaesthetic technique for elective Caesarean deliveries. Hypotension is the most common side-effect and has both maternal and neonatal consequences. Different strategies have been attempted to prevent spinal-induced hypotension, including the use of low-dose bupivacaine. We conducte...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,meta分析,评审

    doi:10.1093/bja/aer200

    authors: Arzola C,Wieczorek PM

    更新日期:2011-09-01 00:00:00

  • Epidural analgesia compared with peripheral nerve blockade after major knee surgery: a systematic review and meta-analysis of randomized trials.

    abstract::The relative analgesic efficacy and side-effect profile of peripheral nerve blockade (PNB) techniques compared with lumbar epidural analgesia for major knee surgery is unclear. We undertook a systematic review and meta-analysis of all randomized trials comparing epidural analgesia with PNB for major knee surgery. Eigh...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,meta分析,评审

    doi:10.1093/bja/aem373

    authors: Fowler SJ,Symons J,Sabato S,Myles PS

    更新日期:2008-02-01 00:00:00

  • Mitochondrial redox state in the critically ill.

    abstract::Abnormal oxygen use and organ failure in the critically ill may result from 'poisoning' of mitochondrial function. Measurement of arterial ketone body ratio (AKBR) has been proposed to reflect mitochondrial redox state and may provide a useful marker to monitor mitochondrial function in the critically ill. We measured...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/83.2.325

    authors: Yassen KA,Galley HF,Lee A,Webster NR

    更新日期:1999-08-01 00:00:00

  • Use of a mechanical simulator for training in applying cricoid pressure.

    abstract::Using an airway management training model, we have assessed anaesthesia personnel in their use of correct cricoid force and ability to retain this skill after a short training programme. A perspex device, working on a hydraulic principle, was used to measure cricoid pressure when applied to the model. After initial as...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/77.4.468

    authors: Ashurst N,Rout CC,Rocke DA,Gouws E

    更新日期:1996-10-01 00:00:00

  • Neuromuscular dose-response studies: determining sample size.

    abstract:BACKGROUND:Investigators planning dose-response studies of neuromuscular blockers have rarely used a priori power analysis to determine the minimal sample size their protocols require. Institutional Review Boards and peer-reviewed journals now generally ask for this information. This study outlines a proposed method fo...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aeq310

    authors: Kopman AF,Lien CA,Naguib M

    更新日期:2011-02-01 00:00:00

  • The suppression of spinal F-waves by propofol does not predict immobility to painful stimuli in humans.

    abstract:BACKGROUND:The immobilizing effects of volatile anaesthetics are primarily mediated at the spinal level. A suppression of recurrent spinal responses (F-waves), which reflect spinal excitability, has been shown for propofol. We have assessed the concentration-dependent F-wave suppression by propofol and related it to th...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aei283

    authors: Baars JH,Tas S,Herold KF,Hadzidiakos DA,Rehberg B

    更新日期:2006-01-01 00:00:00

  • Electromyographic responses to small doses of suxamethonium in children after burns.

    abstract::Integrated electromyographic studies in burned patients, and in normal controls, during the administration of small doses of suxamethonium (0.1 or 0.2 mg kg-1) have shown that the level of paralysis and the duration of paralysis are significantly increased in burn patients and that the effect is greater with larger bu...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/59.8.1017

    authors: Brown TC,Bell B

    更新日期:1987-08-01 00:00:00

  • Comparison of high- and low-dose intrathecal morphine for spinal fusion in children.

    abstract:BACKGROUND:The purpose of this prospective study was to assess the blood-sparing effect, the quality of analgesia, and the incidence of side-effects of a low-dose regime of intrathecal opioids (ITO) when compared with those of a high-dose regime in scoliosis surgery in children. METHODS:Forty-six children were randoml...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/bja/aen025

    authors: Eschertzhuber S,Hohlrieder M,Keller C,Oswald E,Kuehbacher G,Innerhofer P

    更新日期:2008-04-01 00:00:00

  • Extradural morphine for the relief of pain following caesarean section.

    abstract::Thirty patients took part in a double-blind trial to compare morphine 10 mg i.m. with morphine 5 mg into the extradural space for pain relief following Caesarean section. With the extradural route the mean time to first analgesia was 7.95 h compared with 4.75 h for the i.m. route. The mean number of further doses of d...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章

    doi:10.1093/bja/55.12.1201

    authors: Chambers WA,Mowbray A,Wilson J

    更新日期:1983-12-01 00:00:00

  • Postoperative myocardial ischaemia in patients with recent myocardial infarction.

    abstract::Fifteen patients (10 men and five women; mean age 67.3 yr) with a history of a recent (less than 1 yr) myocardial infarction underwent ambulatory ECG monitoring for 5 days after non-cardiac surgery. The duration, number and severity of ischaemic episodes were maximal within the first 12 h after surgery and again on th...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/67.3.317

    authors: Metzler H,Mahla E,Rotman B,Rehak P,Potisk S,List WF

    更新日期:1991-09-01 00:00:00

  • Effects of thoracic epidural anaesthesia on microvascular gastric mucosal oxygenation in physiological and compromised circulatory conditions in dogs.

    abstract:BACKGROUND:The effects of thoracic epidural anaesthesia (TEA) on gastric mucosal microvascular haemoglobin oxygenation (microHbO(2)) are unclear. At the splanchnic level, reduction of sympathetic tone may promote vasodilation and increase microHbO(2). However, these splanchnic effects are counteracted by systemic effec...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aeh235

    authors: Schwarte LA,Picker O,Höhne C,Fournell A,Scheeren TW

    更新日期:2004-10-01 00:00:00

  • Synergistic effects of sepsis and prematurity on neonatal postoperative mortality.

    abstract:INTRODUCTION:Compared with term neonates, preterm babies are more likely to die from sepsis. However, the combined effects of sepsis and prematurity on neonatal postoperative mortality are largely unknown. Our objective was to quantify the proportion of neonatal postoperative mortality that is attributable to the syner...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.bja.2020.07.026

    authors: Mpody C,Shepherd EG,Thakkar RK,Dairo OO,Tobias JD,Nafiu OO

    更新日期:2020-12-01 00:00:00

  • Metoclopramide for nausea and vomiting prophylaxis during and after Caesarean delivery: a systematic review and meta-analysis.

    abstract::Nausea and vomiting occur commonly during and after Caesarean delivery (CD) performed under neuraxial anaesthesia. Metoclopramide is a prokinetic agent reported to be safe in parturients. This meta-analysis assesses the efficacy of metoclopramide for prophylaxis against intra- and postoperative nausea and vomiting (IO...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,meta分析,评审

    doi:10.1093/bja/aer509

    authors: Mishriky BM,Habib AS

    更新日期:2012-03-01 00:00:00

  • Randomized trial of red cell washing for the prevention of transfusion-associated organ injury in cardiac surgery.

    abstract:Background:Experimental studies suggest that mechanical cell washing to remove pro-inflammatory components that accumulate in the supernatant of stored donor red blood cells (RBCs) might reduce inflammation and organ injury in transfused patients. Methods:Cardiac surgery patients at increased risk of large-volume RBC ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1093/bja/aex083

    authors: Wozniak MJ,Sullo N,Qureshi S,Dott W,Cardigan R,Wiltshire M,Morris T,Nath M,Bittar N,Bhudia SK,Kumar T,Goodall AH,Murphy GJ

    更新日期:2017-05-01 00:00:00

  • Association between postoperative delirium and postoperative cerebral oxygen desaturation in older patients after cardiac surgery.

    abstract:BACKGROUND:Near-infrared spectroscopy non-invasively measures regional cerebral oxygen saturation. Intraoperative cerebral desaturations have been associated with worse neurological outcomes. We investigated whether perioperative cerebral desaturations are associated with postoperative delirium in older patients after ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1016/j.bja.2019.09.042

    authors: Eertmans W,De Deyne C,Genbrugge C,Marcus B,Bouneb S,Beran M,Fret T,Gutermann H,Boer W,Vander Laenen M,Heylen R,Mesotten D,Vanelderen P,Jans F

    更新日期:2020-02-01 00:00:00

  • Effect of oral doxapram on morphine-induced changes in the ventilatory response to carbon dioxide.

    abstract::A double-blind crossover volunteer trial has been carried out to determine if oral doxapram reduces the respiratory depression caused by morphine 0.12 mg kg-1 i.m. Doxapram was given to the subjects 90 min before the morphine and significantly reduced the displacement of the ventilatory response to carbon dioxide caus...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/62.2.159

    authors: Randall NP,Pleuvry BJ,Fazackerley EJ,Modla CY,Prescott LF,Healy TE

    更新日期:1989-02-01 00:00:00

  • Post-circumcision analgesia: comparison of topical analgesia with dorsal nerve block using the midline and lateral approaches.

    abstract::Forty-five patients undergoing circumcision were allocated randomly to one of three study groups to compare topical analgesia with dorsal nerve block using the midline or lateral approach. Pain scores, side effects and analgesic requirements were recorded after surgery. Patients who received topical analgesia required...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/73.4.437

    authors: Chambers FA,Lee J,Smith J,Casey W

    更新日期:1994-10-01 00:00:00

  • Influence of muscle temperature and forearm position on evoked electromyography in the hand.

    abstract::We have examined the correlation between the evoked electromyographic response in the first dorsal interosseous muscle of the hand, temperature and forearm position in 40 female patients after enflurane anaesthesia with spontaneous breathing. In 20 patients the supinated forearm with the wrist extended was immobilized...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/72.4.407

    authors: Smith DC,Booth JV

    更新日期:1994-04-01 00:00:00

  • The intubating laryngeal mask airway compared with direct laryngoscopy.

    abstract::We have compared the ability of naïve intubators to intubate the trachea using a laryngoscope and an intubating laryngeal mask airway (ILMA) after receiving basic training, in a randomized, prospective, crossover study in 60 patients. Ventilation of the lungs via the ILMA was also compared with ventilation with a face...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/83.4.615

    authors: Avidan MS,Harvey A,Chitkara N,Ponte J

    更新日期:1999-10-01 00:00:00