Gold embedded chitosan nanoparticles with cell membrane mimetic polymer coating for pH-sensitive controlled drug release and cellular fluorescence imaging.

abstract：:The objective of the present study was to incorporate strontium into calcium phosphate cement combined with a lower single-dose local administration of bone morphogenetic protein-2 to enhance its in vivo biodegradation and bone tissue growth. After the creation of a rodent critical-sized femoral metaphyseal bone defec...

journal_title：Journal of biomaterials applications

authors： Tao Z,Zhou W,Jiang Y,Wu X,Xu Z,Yang M,Xie J

更新日期：2018-07-01 00:00:00

abstract：:Sodium alginate is an effective biomaterial for tissue engineering applications. Non-purified alginate is contaminated with protein, lipopolysaccharide, DNA, and RNA, which could elicit adverse immunological reactions. We developed a purification protocol to generate biocompatible alginate based on (a) activated charc...

journal_title：Journal of biomaterials applications

authors： Sondermeijer HP,Witkowski P,Woodland D,Seki T,Aangenendt FJ,van der Laarse A,Itescu S,Hardy MA

更新日期：2016-10-01 00:00:00

abstract：:A biodegradable polylactic acid composite containing tricalcium phosphate microsphere was fabricated. The composite exhibited enhanced biocompatibility and a well-interconnected porous structure that enabled tissue ingrowth after degradation. The tricalcium phosphate microspheres had an average size of 106 ± 43 μm and...

journal_title：Journal of biomaterials applications

authors： Shin DY,Kang MH,Kang IG,Kim HE,Jeong SH

更新日期：2018-05-01 00:00:00

abstract：:This study reports the properties of tableted microparticles based on high-amylose corn starch (HACS)-pectin blend polymers as the controlled release system for diclofenac sodium (DS). HACS-pectin blend microparticles are prepared through a modified process by the spray drying technique, which is a widely used microen...

journal_title：Journal of biomaterials applications

authors： Desai KG

更新日期：2007-01-01 00:00:00

abstract：:Biomaterials and devices have been used in a variety of applications ranging from disposable extracorporeal devices and soft and hard tissue augmentation, to total artificial internal organs. However, there are risks and failures in each application which are a result of undesirable biological interactions. This artic...

journal_title：Journal of biomaterials applications

authors： Jayabalan M

更新日期：1993-07-01 00:00:00

abstract：:This investigation describes the synthesis and in vitro evaluation of cationic hydrogel sub-microparticles based on polydimethylaminoethylmethacrylate for oral insulin delivery. Polymerization of dimethylaminoethylmethacrylate was carried out in aqueous medium with potassium persulfate as the initiator. Quaternization...

journal_title：Journal of biomaterials applications

authors： Sonia TA,Sharma CP

更新日期：2013-07-01 00:00:00

abstract：:Three types of commercially available ultra-high molecular weight polyethylene (UHMWPE) acetabular cups currently used in total hip arthroplasty have been studied by means of Raman micro-spectroscopy to unfold the microstructural modification induced by the oxidative degradation after accelerated aging with and withou...

journal_title：Journal of biomaterials applications

authors： Puppulin L,Zhu W,Sugano N,Pezzotti G

更新日期：2015-01-01 00:00:00

abstract：:Polylactic acid (PLA)-derived polymers are widely used in many biotechnological fields, thanks to their biocompatibility and resorbability through natural pathways. Moreover, PLA is one of the few polymers in which both the properties and the stereochemical structure can be easily modified, making possible a specific ...

journal_title：Journal of biomaterials applications

authors： Renò F,Rizzi M,Cannas M

更新日期：2012-08-01 00:00:00

abstract：:Solvent-based methods are commonly employed for the production of polyester-based samples and coatings in both medical device production and research. The influence of solvent casting and subsequent drying time was studied using thermal analysis, spectroscopy and weight measurement for four grades of 50 : 50 poly(lact...

journal_title：Journal of biomaterials applications

authors： Manson J,Dixon D

更新日期：2012-01-01 00:00:00

abstract：:Using a hydraulic stress simulator, the mechanical behavior of the porcine pericardium used in the construction of cardiac valve leaflets was characterized following the same procedure employed with calf pericardium in Part 1 of this study. One hundred fifty pairs of tissue samples were subjected to tensile testing to...

journal_title：Journal of biomaterials applications

authors： García Páez JM,Carrera A,Herrero EJ,Millán I,Rocha A,Cordón A,Sainz N,Mendez J,Castillo-Olivares JL

更新日期：2001-07-01 00:00:00

abstract：:A multifunctional targeted nanoplatform combining photothermal therapy and chemotherapy has emerged as a promising strategy for comprehensive therapies of breast cancer. In this study, we constructed human epidermal growth factor receptor 2 (Her2)-targeted gold nanoshelled poly(lactic-co-glycolic acid) hybrid nanocaps...

journal_title：Journal of biomaterials applications

authors： Dong Q,Wan C,Yang H,Zheng D,Xu L,Zhou Z,Xie S,Du J,Li F

更新日期：2020-09-01 00:00:00

abstract：:Chitosan-glutaraldehyde microparticles were produced by emulsion crosslinking method to be used as drug delivery system for polyphenols from Thymus serpyllum L. aqueous extract. The effect of preparation conditions, chitosan concentration (1.5-3% w/v), and glutaraldehyde/chitosan (GA/Ch) mass ratio (0.15-1.20) on wate...

journal_title：Journal of biomaterials applications

authors： Trifković K,Milašinović N,Djordjević V,Zdunić G,Kalagasidis Krušić M,Knežević-Jugović Z,Šavikin K,Nedović V,Bugarski B

更新日期：2015-11-01 00:00:00

abstract：:Phase-sensitive in situ gel-forming controlled release formulations of insulin were prepared using poly(lactide-co-glycolide) and a solvent system consisting of various proportions of benzyl benzoate and benzyl alcohol. The in vitro release samples of formulations were assayed for insulin content by enzyme linked immu...

journal_title：Journal of biomaterials applications

authors： Dhawan S,Kapil R,Kapoor DN

更新日期：2011-03-01 00:00:00

abstract：:The development and improvement of medical devices and artificial organs is critically dependent on the realisation of the importance of the interactions between materials and body tissues. In this regard, the evaluation of biocompatibility assumes paramount importance. This paper reviews the hematological aspects of ...

journal_title：Journal of biomaterials applications

authors： Banerjee R,Nageswari K,Puniyani RR

更新日期：1997-07-01 00:00:00

abstract：:Novel in situ polymerizable liquid three-arm biodegradable oligomeric polyesters based upon glycolic acid (GA), L-lactic acid (LLA), and their copolymers are synthesized and characterized. Injectable and in situ curable polymer neat resins and their composites formulated with bioabsorbable beta-tricalcium phosphate ar...

journal_title：Journal of biomaterials applications

authors： Xie D,Park JG,Zhao J,Turner CH

更新日期：2007-07-01 00:00:00

abstract：:Poor blood circulation makes it difficult for antitubercular drugs to achieve effective bactericidal concentration at tuberculose focus. The residual Mycobacterium tuberculosis around surgical wound would multiply, resulting in nonunion or sinus formation. Carbon nanotubes have strong tissue penetration and can cross ...

journal_title：Journal of biomaterials applications

authors： Chen G,Wu Y,Yu D,Li R,Luo W,Ma G,Zhang C

更新日期：2019-02-01 00:00:00

abstract：:To develop biocompatible composite microspheres for novel hemostatic use, we designed and prepared a novel biomaterial, composite microspheres consisting of carboxymethyl chitosan, sodium alginate, and collagen (CSCM). The ultra-structure of CSCM was investigated by scanning electron microscopy assay. In hemostatic fu...

journal_title：Journal of biomaterials applications

authors： Shi X,Fang Q,Ding M,Wu J,Ye F,Lv Z,Jin J

更新日期：2016-02-01 00:00:00

abstract：:The incidence of fractures increases with age. This is partly due to extraosseous factors and partly to the increased fragility of the bone material itself. Ageing adversely affects the "quality" of human bone material, its elastic and ultimate properties. The hypothesis here is that these effects are caused by factor...

journal_title：Journal of biomaterials applications

authors： Zioupos P

更新日期：2001-01-01 00:00:00

abstract：:Injectable thermo-sensitive hydrogels have a potential application in bone tissue engineering for their sensitivities and minimal invasive properties. Human dental pulp stem cells have been considered a promising tool for tissue reconstruction. The objective of this study was to investigate the proliferation and osteo...

journal_title：Journal of biomaterials applications

authors： Chen Y,Zhang F,Fu Q,Liu Y,Wang Z,Qi N

更新日期：2016-09-01 00:00:00

abstract：:The quality and quantity of bone are crucial to the success of dental implant treatment. Recently, bone grafting materials have reached some limitations. This study aimed to evaluate the biocompatibility of novel drug delivery material, injectable methacrylated hyaluronic acid hydrogel incorporated with different rati...

journal_title：Journal of biomaterials applications

authors： Areevijit K,Dhanesuan N,Luckanagul JA,Rungsiyanont S

更新日期：2020-11-04 00:00:00

abstract：:The in vitro effect of platelet-rich plasma (PRP) on cell loading, proliferation, and osteogenic differentiation of human mesenchymal stem cells (MSC) is assessed on distinct resorbable and synthetic calcium phosphate scaffolds. A high specific surface area scaffold composed of calcium-deficient hydroxyapatite (CDHA; ...

journal_title：Journal of biomaterials applications

authors： Kasten P,Vogel J,Beyen I,Weiss S,Niemeyer P,Leo A,Lüginbuhl R

更新日期：2008-09-01 00:00:00

abstract：:Sustained intestinal delivery of thiamine hydrochloride (Vitamin B(1); VB(1)) and pyridoxine hydrochloride (Vitamin B(6); VB(6)) seems to be a feasible alternative to existing therapy. The vitamins (VB(1)/VB(6)) intercalated in montmorillonite (MMT) and intercalated VB(1)/VB(6)-MMT hybrid is further used for synthesis...

journal_title：Journal of biomaterials applications

authors： Kevadiya BD,Joshi GV,Patel HA,Ingole PG,Mody HM,Bajaj HC

更新日期：2010-08-01 00:00:00

abstract：:Silicate-based cements have been developed as a class of bioactive and biodegradable bone cements owing to their good in vitro bioactivity and ability to dissolve in a simulated body fluid. Until recently, however, the in vivo evidence of their ability to support bone regeneration is still scarce. In the present study...

journal_title：Journal of biomaterials applications

authors： Ma B,Huan Z,Xu C,Ma N,Zhu H,Zhong J,Chang J

更新日期：2017-08-01 00:00:00

abstract：:The aim of this study was to examine the release of silica (Si), calcium (Ca), phosphorous (P), and fluoride (F) from conventional glass ionomer cement (GI) and resin-modified glass ionomer cement (LCGI), containing different quantities of bioactive glass (BAG). Further aim was to evaluate in vitro biomineralization o...

journal_title：Journal of biomaterials applications

authors： Yli-Urpo H,Vallittu PK,Närhi TO,Forsback AP,Väkiparta M

更新日期：2004-07-01 00:00:00

abstract：:Transarterial embolization is an established minimally invasive treatment for solid tumors. Unintended inflammation, foreign body reactions and ischemia-triggered neoangiogenesis are clinical drawbacks of permanent embolic materials. The aim of the current study was to characterize a new type of biodegradable starch m...

journal_title：Journal of biomaterials applications

authors： Sommer CM,Do TD,Schlett CL,Flechsig P,Gockner TL,Kuthning A,Vollherbst DF,Pereira PL,Kauczor HU,Macher-Göppinger S

更新日期：2018-02-01 00:00:00

abstract：:Fabrication of osteoconductive scaffold with osteoinductive capability and appropriate resorption rate is of great significance for treating bone defects. To achieve this aim, strontium-substituted calcium sulfate hemihydrate (Sr-CSH) and hydroxyapatite (HA) were mixed to develop a novel composite. Sr-CSH containing 5...

journal_title：Journal of biomaterials applications

authors： Chang H,Xiang H,Yao Z,Yang S,Tu M,Zhang X,Yu B

更新日期：2020-07-01 00:00:00

abstract：:Two series of glasses of general formula (2-p) SiO2.1.1Na2O.CaO.pP2O5.xZnO (p=0.10, 0.20; x=0.0, 0.16, 0.35, and 0.78) have been analyzed for physico-chemical surface features before and after contact with simulated body fluid, morphological characteristics, and osteoblast-like cells behavior when cultured on them. Th...

journal_title：Journal of biomaterials applications

authors： Lusvardi G,Malavasi G,Menabue L,Menziani MC,Pedone A,Segre U,Aina V,Perardi A,Morterra C,Boccafoschi F,Gatti S,Bosetti M,Cannas M

更新日期：2008-05-01 00:00:00

abstract：:This study's aim consists of evaluating the adhesion and proliferation of mesenchymal stem cells (MSCs) derived from rat bone marrow on nanoparticle Titanium (Ti) surface. Hence, passage 3 MSCs were, respectively, seeded on nanoparticle Ti and pure Ti surfaces and then cultured for 32 h. Cell morphology and viability ...

journal_title：Journal of biomaterials applications

authors： Chen L,Sun J,Zhu Z,Wu K,Li W,Liu H,Xu S

更新日期：2013-01-01 00:00:00

abstract：:The purpose of this investigation is to study the effect of long-term subcutaneous aluminum polymeric implants on aluminum release and accumulation in various tissues in rats. The implants were formulated using silicone rubber and polyurethane polymers and three different aluminum salts. The polymeric matrices were ev...

journal_title：Journal of biomaterials applications

authors： Pathak YV,Vanmeeteren R,Dwivedi C

更新日期：1996-07-01 00:00:00

abstract：:Nonviral gene delivery systems are finding widespread use due to their safety, rapid and economical production, and ease of modification. In this work, series of N-alkyl-substituted linear polyethylenimine (CP) polymers have been synthesized, characterized, and investigated about how degree of substitution (hydrophobi...

journal_title：Journal of biomaterials applications

authors： Bansal R,Kumar P

更新日期：2017-07-01 00:00:00