Medication-related osteonecrosis of the mandible: an unusual presentation and treatment.

Abstract:

:A 71-year-old woman was referred to the clinic with extensive medication-related osteonecrosis of the jaw (MRONJ) involving the mandible. She had received 7 years of zoledronate therapy. On cone beam computed tomography, the MRONJ presented as a large sequestrum spanning from the left to the right condylar process, surrounded by thick sub-periosteal bone. The sequestrum was excised via an intraoral approach, leaving the newly formed sub-periosteal bone as a neo-mandible. The patient recovered well from the operation and was discharged 5 days after surgery. She healed completely without complications. This case report presents an alternative surgical treatment that may be considered if there is clinically stable sub-periosteal bone surrounding extensive MRONJ.

authors

Rothweiler R,Voss PJ,Schmelzeisen R,Metzger MC

doi

10.1016/j.ijom.2020.07.033

subject

Has Abstract

pub_date

2020-08-23 00:00:00

eissn

0901-5027

issn

1399-0020

pii

S0901-5027(20)30296-4

pub_type

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