Secondary tumors of the bladder: A survival outcome study.

Abstract:

:The urinary bladder may be involved by a variety of secondary tumors that originate from other organs. Bladder secondary tumors are rare and may be mistaken as bladder primary tumors because of their overlapping morphologic features. To avoid the diagnostic pitfalls, we analyzed the clinicopathologic features of bladder secondary tumors in a large cohort of patients. Our patient cohort consisted of 45 females and 38 males with a mean age of 58.7 ± 15.4 years (range 10-87 years). The tumors involved the bladder via direct extension from adjacent organs (n = 42) and distant metastasis (n = 41). In females, the majority of secondary tumors originated from the gynecologic tract (n = 25), and other common origins included the colon/rectum (n = 5) and breast (n = 4). In males, the most common origin was the prostate (n = 18), followed by the colon/rectum (n = 4) and kidney (n = 3). 75.9% of the secondary tumors were adenocarcinoma (n = 63), and other common tumor types included sarcoma (n = 6), squamous cell carcinoma (n = 5), melanoma (n = 4), and neuroendocrine carcinoma (n = 3). 67.5% of patients (n = 56) died of the disease with a median overall survival of 23 months from the time of secondary involvement of the bladder. Patients with secondary tumors via direct extension had a median survival time of 20 months, which was not significantly different from that for patients with secondary involvement via distant metastasis (24 months) (p = 0.83). Median survival in cases with prostate primary was 20 months as compared to 23 months for all other tumor types (p = 0.68). The majority of secondary tumors are composed of adenocarcinoma, which highlights the importance of differentiating primary from secondary involvement in bladder adenocarcinoma. Regardless of the origin, bladder secondary tumors are associated with a poor prognosis.

journal_name

Ann Diagn Pathol

authors

Hamza A,Hwang MJ,Czerniak BA,Guo CC

doi

10.1016/j.anndiagpath.2020.151593

subject

Has Abstract

pub_date

2020-10-01 00:00:00

pages

151593

eissn

1092-9134

issn

1532-8198

pii

S1092-9134(20)30136-2

journal_volume

48

pub_type

杂志文章
  • A patient with prostate cancer and multiple myeloma-diagnostics and possible association of both diseases.

    abstract::In this report, we describe a case of a patient with prostate cancer and multiple myeloma as the second metachronous malignant disease. To our knowledge, synchronous occurrence of bone marrow prostate cancer metastases and multiple myeloma-as it was found in the clinical disease course of our patient-has not been docu...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章

    doi:10.1016/j.anndiagpath.2011.04.010

    authors: Sučić M,Bišof V,Cačić M,Kinda SB,Kolenc D,Ljubić N,Sučić T,Potočki K

    更新日期:2012-12-01 00:00:00

  • Primary cutaneous histiocytic sarcoma: A report of five cases with primary cutaneous involvement and review of the literature.

    abstract:INTRODUCTION:Histiocytic sarcoma is an extremely rare hematologic malignancy of histiocytic origin. Five cases of primary cutaneous histiocytic sarcoma are presented. MATERIALS AND METHODS:Cases of primary cutaneous histiocytic sarcoma were identified using a natural language search from the dermatopathology data base...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章,评审

    doi:10.1016/j.anndiagpath.2017.10.004

    authors: Magro CM,Kazi N,Sisinger AE

    更新日期:2018-02-01 00:00:00

  • Clear cell renal cell carcinoma with focal renal angiomyoadenomatous tumor-like area.

    abstract::Recently, renal angiomyoadenomatous tumor (RAT) has been identified. However, there are no descriptions about clear cell renal cell carcinoma (RCC) with focal RAT-like features. A 33-year-old Japanese man was found to have a tumor in the left kidney. Macroscopically, the tumor extended into the perinephric fat tissue,...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章

    doi:10.1016/j.anndiagpath.2010.03.003

    authors: Kuroda N,Hosokawa T,Michal M,Hes O,Sima R,Ohe C,Lee GH

    更新日期:2011-06-01 00:00:00

  • Frozen section discrepancy in the evaluation of nonneoplastic central nervous system samples.

    abstract::Frozen section (FS) for intraoperative evaluation of central nervous system (CNS) lesions provides the neurosurgeon with a rapid preliminary pathologic diagnosis. Diagnosis of nonneoplastic lesions is particularly challenging in this venue. To highlight common diagnostic pitfalls, we sought to identify discrepancies b...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章

    doi:10.1016/j.anndiagpath.2009.05.006

    authors: Plesec TP,Prayson RA

    更新日期:2009-12-01 00:00:00

  • So-called sclerosing hemangioma of lung: current concept.

    abstract::Sclerosing hemangioma of the lung is a rare neoplasm with polymorphic histologic features. Despite various patterns, there are 2 unifying cellular components: "surface cells" and "round cells." Although histogenesis has been debated for decades, most ultrastructural, immunocytochemical, and molecular studies strongly ...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章,评审

    doi:10.1016/j.anndiagpath.2009.07.002

    authors: Kalhor N,Staerkel GA,Moran CA

    更新日期:2010-02-01 00:00:00

  • Evaluation and reporting of biopsies from the columnar-lined esophagus and gastro-esophageal junction (GEJ).

    abstract::This review is part of a collaboration between the American Registry of Pathology (the publisher of the Armed Forces Institute of Pathology Fascicles) and Annals of Diagnostic Pathology. It is in a series of expert recommendations on topics encountered in daily practice. The authors, two pathologists and a gastroenter...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章,评审

    doi:10.1016/j.anndiagpath.2019.02.012

    authors: Montgomery EA,Canto MI,Srivastava A

    更新日期:2019-04-01 00:00:00

  • Papillary renal cell carcinoma with prominent spindle cell stroma - tumor mimicking mixed epithelial and stromal tumor of the kidney: Clinicopathologic, morphologic, immunohistochemical and molecular genetic analysis of 6 cases.

    abstract::Papillary renal cell carcinoma (PRCC) is currently a well-studied type of RCC. In addition to PRCC type 1, there are a number of other subtypes and variants of PRCCs which have been reported. We describe a series of 6 PRCCs with papillary, micropapillary and/or tubulopapillary architecture and prominent spindle cell s...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章

    doi:10.1016/j.anndiagpath.2019.151441

    authors: Rogala J,Kojima F,Alaghehbandan R,Agaimy A,Martinek P,Ondic O,Ulamec M,Sperga M,Michalova K,Pivovarcikova K,Pitra T,Hora M,Ferak I,Marečková J,Michal M,Hes O

    更新日期:2020-02-01 00:00:00

  • Parachordoma: a clinicopathologic and immunohistochemical study of four cases of an unusual soft tissue neoplasm.

    abstract::Four soft tissue tumors corresponding with the previously reported parachordoma are described. Three of the patients were men, and one was a woman, and their ages ranged from 14 to 53 years (mean age, 29). The tumors were located either superficially or within muscle, and, in one case, involved a tendon. Histologicall...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章

    doi:10.1016/s1092-9134(97)80003-2

    authors: Fisher C,Miettinen M

    更新日期:1997-10-01 00:00:00

  • Distinctive immunohistochemical staining in littoral cell angioma using ERG and WT-1.

    abstract::Littoral cell angioma (LCA) is a rare vascular tumor of the spleen. It has an immunohistochemical staining pattern that is somewhat distinctive but can still be occasionally confused with other vascular and stromal proliferations in the spleen. In this study, LCA was evaluated using Ets-related gene (ERG) and Wilms tu...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章

    doi:10.1016/j.anndiagpath.2015.02.007

    authors: O'Malley DP,Kim YS,Weiss LM

    更新日期:2015-06-01 00:00:00

  • Biphenotypic sinonasal sarcoma: A series of six cases with evaluation of role of β-catenin immunohistochemistry in differential diagnosis.

    abstract:INTRODUCTION:Biphenotypic sinonasal sarcoma (BSNS) is a recently described mesenchymal tumor exclusive to the sinonasal region. It is a low grade sarcoma, displaying evidence of myogenic and neural differentiation. Role of β-catenin immunohistochemistry in distinguishing it from its morphological mimics is not well-est...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章

    doi:10.1016/j.anndiagpath.2017.11.005

    authors: Kakkar A,Rajeshwari M,Sakthivel P,Sharma MC,Sharma SC

    更新日期:2018-04-01 00:00:00

  • Utility of thin-layer preparations in the endometrial cytology: evaluation of benign endometrial lesions.

    abstract::The purpose of the current study was to examine the use of thin-layer cytologic (TLC) preparation compared to conventional cytologic preparation (CCP) in the normal endometrium (proliferative, secretory, atrophic) and endometrial glandular and stromal breakdown (EGBD). During a 6-month period, we compiled 158 cases by...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章

    doi:10.1016/j.anndiagpath.2007.05.005

    authors: Norimatsu Y,Kouda H,Kobayashi TK,Moriya T,Yanoh K,Tsukayama C,Miyake Y,Ohno E

    更新日期:2008-04-01 00:00:00

  • Observer reliability in assessment of mitotic activity and MIB-1-determined proliferation rate in pediatric sarcomas.

    abstract::In hematoxylin-eosin-stained sections of 20 pediatric sarcomas the mitotic index was assessed by four experienced pathologists and four less-experienced observers without prior instructions. In adjacent sections immunolabeled for MIB-1, the proliferation index was assessed as the estimated percentage of labeled cells ...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章

    doi:10.1053/adpa.2000.8126

    authors: Molenaar WM,Plaat BE,Berends ER,te Meerman GJ

    更新日期:2000-08-01 00:00:00

  • CD133 expression in oral lichen planus correlated with the risk for progression to oral squamous cell carcinoma.

    abstract::Oral lichen planus (OLP) is a potentially malignant disorder associated with an increased risk for progression to oral squamous cell carcinoma (OSCC). The objective of this study to determine protein expression of cancer stem cell marker CD133 in tissue samples of patients with OLP and evaluate the correlation between...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章

    doi:10.1016/j.anndiagpath.2013.06.004

    authors: Sun L,Feng J,Ma L,Liu W,Zhou Z

    更新日期:2013-12-01 00:00:00

  • Cutaneous angiosarcoma. Analysis of 434 cases from the Surveillance, Epidemiology, and End Results Program, 1973-2007.

    abstract::Cutaneous angiosarcoma is an aggressive malignant mesenchymal vasoformative neoplasm that accounts for 1% of all soft tissue sarcomas. Using data from the National Cancer Institute's Surveillance, Epidemiology, and End Results program, we analyzed the demographics and survival of cutaneous angiosarcoma. The Surveillan...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章

    doi:10.1016/j.anndiagpath.2010.07.012

    authors: Albores-Saavedra J,Schwartz AM,Henson DE,Kostun L,Hart A,Angeles-Albores D,Chablé-Montero F

    更新日期:2011-04-01 00:00:00

  • Lymphoepithelioma-like carcinoma of the breast: report of a case mimicking lymphoma.

    abstract::Only 10 cases of lymphoepithelioma-like carcinoma of the breast have been reported in the literature. This report adds one more case to the published literature. A 62-year-old woman presented with a mass in her left breast on physical examination. The mammographic images showed a 3.0 cm, poorly defined mass in the upp...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章

    doi:10.1016/j.anndiagpath.2004.07.012

    authors: Sanati S,Ayala AG,Middleton LP

    更新日期:2004-10-01 00:00:00

  • Perianal mammary-type myofibroblastoma.

    abstract::We report a unique case of an extramammary mammary-type myofibroblastoma of the perianal region. The patient was a 40-year old female with no significant past history, who presented with a right side painless perianal mass. Gross examination of the excised mass showed a well-circumscribed, apparently encapsulated, nod...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章

    doi:10.1016/j.anndiagpath.2009.08.005

    authors: Zhang Y,Jorda M,Goldblum JR

    更新日期:2010-10-01 00:00:00

  • Dedifferentiated liposarcoma of the cheek.

    abstract::Liposarcomas of the head and neck region are rare; only a few cases have been reported to arise in the cheek or buccal mucosa. Dedifferentiated liposarcoma has rarely been reported in the head and neck region and, to the best of our knowledge, this is the first reported case of dedifferentiated liposarcoma of the chee...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章

    doi:10.1053/j.anndiagpath.2004.07.008

    authors: de la Roza G,Baredes S,Aisner SC

    更新日期:2004-12-01 00:00:00

  • Cholesteryl Ester Storage Disease: An underdiagnosed cause of cirrhosis in adults.

    abstract::Cholesteryl Ester Storage Disease (CESD), is a rare multisystem autosomal recessive disorder and belongs to the broad family of lysosomal storage disorders. It can present anytime from infancy and childhood to even adulthood. The clinical manifestations are generally severe in infants and with milder forms in adults. ...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章,评审

    doi:10.1016/j.anndiagpath.2017.02.005

    authors: Pant M,Oshima K

    更新日期:2017-12-01 00:00:00

  • Correlation of expression of hormone and HER2 receptors with various clinico-pathological prognostic parameters and with each other in malignant breast lesion.

    abstract:BACKGROUND:Estrogen receptors (ER), progesterone receptors (PR) and the human epidermal growth factor receptor-2 (HER2) are basic breast cancer molecular markers that are also best recognized prognostic factors and predictors of type of targeted therapy to be given. The objectives are to study the correlation of expres...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章

    doi:10.1016/j.anndiagpath.2020.151659

    authors: Mohanty SS

    更新日期:2020-11-05 00:00:00

  • Unusual locations of hydatid disease: A 10-year experience from a tertiary reference center in Western Turkey.

    abstract:INTRODUCTION:Hydatid disease is an endemic parasitic infection caused by Echinococcus granulosus mostly seen in the Mediterranean countries. The most affected organ is the liver, however hydatidosis can be found anywhere in the human body. METHODS:The records of patients who were diagnosed with hydatid disease in our ...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章

    doi:10.1016/j.anndiagpath.2017.01.011

    authors: Gun E,Etit D,Buyuktalanci DO,Cakalagaoglu F

    更新日期:2017-08-01 00:00:00

  • Clinicopathologic correlation of programmed death ligand-1 expression in non-small cell lung carcinomas: A report from India.

    abstract:INTRODUCTION:Increased expression of Programmed death ligand-1 (PD-L1) on cancer cells and immune cells predict response to PD-1/PDL1 inhibitors. Data regarding frequency and pattern of PD-L1 expression in NSCLC from India is not available. OBJECTIVES:To analyse PD-L1 expression on tumour cells (TC) and immune cells (...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章

    doi:10.1016/j.anndiagpath.2017.07.001

    authors: Vallonthaiel AG,Malik PS,Singh V,Kumar V,Kumar S,Sharma MC,Mathur S,Arava S,Guleria R,Jain D

    更新日期:2017-12-01 00:00:00

  • Cystic schwannoma of the pancreas.

    abstract::Intrapancreatic schwannoma is a rare neoplasm. We report a case of a 46-year-old man with a cystic schwannoma in the head of the pancreas. This tumor, based on clinical manifestations and radiologic features, was initially suspected to be a cystic mucinous tumor of the pancreas or a pseudocyst. Histologically, the tum...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章,评审

    doi:10.1016/s1092-9134(03)00082-0

    authors: Tan G,Vitellas K,Morrison C,Frankel WL

    更新日期:2003-10-01 00:00:00

  • Brain in the middle ear or nasal cavity: heterotopia or encephalocele?

    abstract::Brain in the middle ear or nasal cavity: heterotopia or encephalocele? The answer to this question is greatly influenced by clinical information. Sometimes, however, this information is insufficient and the pathologist's opinion may influence patient management. It seems that most pathologists tend to get the answer w...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章,评审

    doi:10.1053/j.anndiagpath.2004.04.009

    authors: Heffner DK

    更新日期:2004-08-01 00:00:00

  • Clinical and pathologic predictors of lymph node metastasis in papillary thyroid microcarcinomas.

    abstract::Papillary thyroid microcarcinoma (PTMC) has the highest incidence among all thyroid carcinomas. Although surgery is the primary treatment for PTMC, it inevitably leads to trauma and some complications. To formulate an optimal treatment strategy, we aim to clarify the risk factors for lymph node metastasis (LNM) in PTM...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章

    doi:10.1016/j.anndiagpath.2020.151647

    authors: Zhao L,Sun X,Luo Y,Wang F,Lyu Z

    更新日期:2020-12-01 00:00:00

  • The surgical and cytopathology of viral infections: utility of immunohistochemistry, in situ hybridization, and in situ polymerase chain reaction amplification.

    abstract::The diagnosis of viral infections is an important part of the daily work of a surgical and cytopathologist. Some viral infections, such as human papillomavirus infection of the lower genital tract, are seen commonly, whereas others, such as fatal enteroviral infection, cannot be diagnosed on routine histological exami...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章,评审

    doi:10.1016/j.anndiagpath.2006.02.003

    authors: Nuovo GJ

    更新日期:2006-04-01 00:00:00

  • BK virus histopathologic disease severity does not predict allograft outcome in renal transplant recipients.

    abstract:AIMS:BK polyomavirus nephropathy (BKPyVN) is an important cause of allograft failure after renal transplantation. Despite early screening for the virus, allograft loss from BKPyVN is still experienced in up to 14% of all renal transplant recipients. The aim of this study was to investigate the association between BKPyV...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章

    doi:10.1016/j.anndiagpath.2019.06.012

    authors: Sanders ML,Swee M,Fraer M,Kuppachi S,Ten Eyck P,Rastogi P

    更新日期:2019-10-01 00:00:00

  • Clear cell sarcoma of the mediastinum.

    abstract::A 59-year-old woman presented with a large mediastinal mass. At thoracotomy, the mass was found tightly adherent to the esophageal wall and right lower lobe of the lung. Histological examination showed a solid tumor composed of closely packed nests of cells with clear and eosinophilic cytoplasm, which were strongly an...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章

    doi:10.1016/j.anndiagpath.2008.02.014

    authors: Tirabosco R,Lang-Lazdunski L,Diss TC,Amary MF,Rodriguez-Justo M,Landau D,Lorenzi W,Flanagan AM

    更新日期:2009-06-01 00:00:00

  • Prognostic factors in malignant mixed tumors of the salivary gland: correlation of immunohistochemical markers with histologic classification.

    abstract::Malignant mixed tumor of salivary glands is a rare tumor whose variable behavior and prognosis are related for the most part to the clinical stage and histologic grade of the carcinomatous component. The purpose of this study is to predict prognosis by comparing the histologic grading and subclassification of the carc...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章

    doi:10.1053/adpa.2002.34728

    authors: Xin W,Paulino AF

    更新日期:2002-08-01 00:00:00

  • Core needle biopsy of benign, borderline and in-situ problematic lesions of the breast: Diagnosis, differential diagnosis and immunohistochemistry.

    abstract::Core needle biopsy (CNB) is the most common sampling technique for the histologic evaluation of breast abnormalities. Diagnosing benign proliferative, borderline and some in-situ lesions in CNB is challenging and subject to a significant degree of interobserver variability. In addition, due to the inherent limitations...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章,评审

    doi:10.1016/j.anndiagpath.2019.151407

    authors: Rosa M,Agosto-Arroyo E

    更新日期:2019-12-01 00:00:00

  • Correlation of anal cytology with follow-up histology and Human Papillomavirus genotyping: A 10-year experience from an academic medical center.

    abstract:BACKGROUND:Anal cytology (AC) is accepted as a practical screening modality for anal cancer. However, studies suggest that AC and anal biopsy dysplasia correlation is less robust than in cervicovaginal specimens. The current study goals were to look at our institutional experience in a subset of ACs and correlate with ...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章

    doi:10.1016/j.anndiagpath.2020.151670

    authors: Hopp AM,Pant M,Sniedze S,Parsons LN,Hunt B,Giorgadze T

    更新日期:2020-11-20 00:00:00