Abstract:
:Type 2 diabetes mellitus (T2DM) increases coronary artery disease (CAD) risk. In this study, we used T2DM clinical variables to predict abnormality in thallium-201 myocardial perfusion scans (Th-201 scans). These clinical variables were summed stress score (SSS), summed rest score, and summed difference score (SDS), with data obtained from 368 male and 428 female participants with T2DM. Multiple linear regression results were as follows. In male participants, body mass index (BMI) and creatinine (Cr) were associated with SSS (β = 0.224, p < 0.001; β = 0.140, p = 0.022, respectively), and only BMI was associated with SDS (β = 0.174, p = 0.004). In female participants, BMI and high-density lipoprotein cholesterol level were associated with SSS (β = 0.240, p < 0.001; β = - 0.120, p = 0.048, respectively), and only BMI was correlated with SDS (β = 0.123, p = 0.031). Our multivariate logistic regression indicated that in male and female participants, BMI was the only independent indicator of high SSS (SSS ≥ 9). In this study, we demonstrated that male patients have a higher SSS and SDS than female patients do in Th-201 scans for T2DM in a Chinese population. For male and female patients, BMI was the strongest predictor of abnormality in Th-201 scans. Our results can help clinicians identify patients with T2DM at high risk of CAD.
journal_name
Heart Vesselsjournal_title
Heart and vesselsauthors
Lu CH,Pei D,Wu CZ,Kua HC,Liang YJ,Chen YL,Lin JDdoi
10.1007/s00380-020-01681-2subject
Has Abstractpub_date
2020-08-20 00:00:00eissn
0910-8327issn
1615-2573pii
10.1007/s00380-020-01681-2pub_type
杂志文章abstract::Warfarin-induced skin necrosis is the rare but potentially devastating complication of anticoagulant therapy and commonly occurs in previously undetected C- and S-protein deficient patients. Because routine preoperative examination does not include protein C and S level measurement, detection of these patients preoper...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-006-0935-z
更新日期:2007-01-01 00:00:00
abstract::Percutaneous transvenous mitral commissurotomy (PTMC) increases peak oxygen uptake (VO2) chronically, but not acutely, despite early symptomatic improvements. Analysis of transient VO2 responses to submaximal exercise (an exercise regimen more comparable to the patients' daily activities than that provided by maximal ...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/BF02911391
更新日期:1995-01-01 00:00:00
abstract::Chronic inflammation has received a great deal of attention due to the role it plays in cardiovascular disease (CVD). The cardio-ankle vascular index (CAVI) has recently been developed to evaluate arterial stiffness. This index is independent of blood pressure at the time that it is measured, making it a better measur...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-011-0182-9
更新日期:2012-09-01 00:00:00
abstract::Primary myocardial involvement is common in systemic sclerosis (SSc). We evaluated the atrial and ventricular electromechanical characteristics by using tissue Doppler echocardiography in SSc patients with subclinical cardiac involvement. Twenty-seven consecutive patients (24 women; mean age +/- SD 49.9 +/- 11.3 years...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-009-1197-3
更新日期:2010-05-01 00:00:00
abstract::A transient left ventricular apical ballooning (so-called "ampulla" or "Takotsubo-shaped" cardiomyopathy) with type I CD36 deficiency is described in a 71-year-old woman. The patient was referred because of chest pain and worsening of dyspnea. Electrocardiogram showed T-wave inversions on the precordal leads, and acut...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-004-0787-3
更新日期:2005-05-01 00:00:00
abstract::In children, up to 10% of the cases of arterial hypertension may be caused by a renovascular disease. The etiology of this renovascular disease is most of the time due to a fibromuscular dysplasia (FMD), which causes a noninflammatory intimal-medial fibroplasia leading to luminal compromise. Percutaneous transluminal ...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-009-1147-0
更新日期:2009-11-01 00:00:00
abstract::This study aimed to investigate the combined efficacy in prediction of major adverse cardiac events (MACE) by coronary regional physiological indices including coronary flow reserve (CFR) or fractional flow reserve (FFR) and high-sensitivity cardiac troponin-I (hs-cTnI) or N-terminal pro brain natriuretic peptide (NT-...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-018-1260-z
更新日期:2019-03-01 00:00:00
abstract::Left ventricular non-compaction (LVNC) is genetically heterogeneous. It has been previously shown that LVNC is associated with defects in TAZ, DNTA, LDB3, YWHAE, MIB1, PRDM16, and sarcomeric genes. This study was aimed to investigate sarcomeric gene mutations in a Chinese population with LVNC. From 2004 to 2010, 57 un...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-014-0503-x
更新日期:2015-03-01 00:00:00
abstract::It is unclear whether the electrocardiogram amplitude in the inferior leads (Amp-I) can always predict the height of the origin of right ventricular outflow tract arrhythmias (RVOT-VAs). We analyzed patients who received catheter ablation of multiple RVOT-VAs in the same session in our hospital from 2011 to 2016. Two ...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-018-1235-0
更新日期:2019-02-01 00:00:00
abstract::Hypertrophic cardiomyopathy (HCM) with severe diastolic dysfunction is a major cause of heart failure and sudden cardiac death (SCD) associated with lethal arrhythmia. Although various risk factors for cardiac events have been reported in HCM patients, previous studies have reported that some HCM patients exhibit eith...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-019-01440-y
更新日期:2019-12-01 00:00:00
abstract::To assess left ventricular diastolic properties in response to dynamic exercise, mitral inflow velocity integrals were measured by pulsed-wave Doppler echocardiography in ten patients with myocardial infarction and in ten normal subjects, and simultaneous left ventricular pressure was obtained with micromanometry in t...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::There is no proven therapy for heart failure with preserved ejection fraction (HFpEF). Research has shown beneficial responses to cardiac rehabilitation (CR) among HF patients. To date, there are no reports comparing those responses between patients with HFpEF and those with reduced ejection fraction (HFrEF). The purp...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-018-1128-2
更新日期:2018-08-01 00:00:00
abstract::Existing methods to calculate pre-test probability of obstructive coronary artery disease (CAD) have been established using selected high-risk patients who were referred to conventional coronary angiography. The purpose of this study is to develop and validate our new method for pre-test probability of obstructive CAD...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-014-0515-6
更新日期:2015-09-01 00:00:00
abstract::Electrocardiographic left ventricular hypertrophy (ECG-LVH) gradually regressed after aortic valve replacement (AVR) in patients with severe aortic stenosis. Sokolow-Lyon voltage (SV1 + RV5/6) is possibly the most widely used criterion for ECG-LVH. The aim of this study was to determine whether decrease in Sokolow-Lyo...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-015-0761-2
更新日期:2016-09-01 00:00:00
abstract::Ischemic cardiomyopathy complicated by severe mitral regurgitation (MR) has a poor prognosis. In such cases, whether mitral valve repair for MR improves the prognosis of survival remains unclear. In this study, 50 patients diagnosed with ischemic cardiomyopathy at our hospital between August 1991 and August 1996 were ...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-004-0763-y
更新日期:2004-07-01 00:00:00
abstract::Heme oxygenase (HO)-1 is a rate-limiting enzyme for degrading heme into carbon monoxide. Longer (GT)n repeat of the HO-1 gene (HMOX1) promoter has a lower transcription rate. Subjects with longer GT repeats in the HMOX1 promoter are more likely to have coronary artery disease (CAD) and cardiovascular events. We retros...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-020-01733-7
更新日期:2021-01-03 00:00:00
abstract::We aimed to assess the acute cardiopulmonary effects of a 100-mg oral single dose of sildenafil in patients with idiopathic pulmonary hypertension (IPAH) using a well-validated but less-used noninvasive echocardiographic method for the measurement of both systolic and diastolic pulmonary artery pressure (PAP), by tric...
journal_title:Heart and vessels
pub_type: 临床试验,杂志文章
doi:10.1007/s00380-009-1208-4
更新日期:2010-07-01 00:00:00
abstract::Periprocedural bleeding and thromboembolic events are worrisome complications of catheter ablation for atrial fibrillation (AF). Periprocedural anticoagulation management could decrease the risk of these complications. However, evaluation of the complications from pulmonary vein isolation using cryoballoon related to ...
journal_title:Heart and vessels
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00380-019-01370-9
更新日期:2019-09-01 00:00:00
abstract::Cardiogenic shock frequently leads to death even with intensive treatment. Although the leading cause of cardiogenic shock is acute coronary syndrome (ACS), the clinical characteristics and the prognosis of ACS with cardiogenic shock in the present era still remain to be elucidated. We analyzed clinical characteristic...
journal_title:Heart and vessels
pub_type: 杂志文章,多中心研究
doi:10.1007/s00380-019-01354-9
更新日期:2019-08-01 00:00:00
abstract::Non-ST-elevation myocardial infarction (NSTEMI) and unstable angina (UA) resulted in different degrees of damage to the heart muscle, and yet, when factors related to in-hospital outcomes were examined, these two subsets were often lumped together as non-STelevation acute coronary syndrome. Therefore, we investigated ...
journal_title:Heart and vessels
pub_type: 杂志文章,多中心研究
doi:10.1007/s00380-008-1141-y
更新日期:2009-11-01 00:00:00
abstract::There is controversial data regarding the relationship between uric acid (UA) and coronary artery disease and cardiovascular events. Despite the deleterious effects of hyperuricemia on endothelial function, the effect of UA on myocardial ischemia has not been previously studied. We aimed to investigate the relationshi...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-014-0609-1
更新日期:2016-03-01 00:00:00
abstract::We explored the influence of global longitudinal strain (GLS) measured with two-dimensional speckle-tracking echocardiography on left ventricular mass regression (LVMR) in patients with pure aortic stenosis (AS) and normal left ventricular function undergoing aortic valve replacement (AVR). The study population includ...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-012-0308-8
更新日期:2013-11-01 00:00:00
abstract::Cardiac systolic (left ventricular ejection fraction) and diastolic (mitral inflow velocity pattern and/or mitral deceleration time) function were reported as predictors of clinical outcome or left ventricular remodeling in patients with acute myocardial infarction (AMI). Recently, a new index (Doppler-derived index c...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-003-0735-7
更新日期:2004-03-01 00:00:00
abstract::Compared to conscious sedation (CS), the use of general anesthesia (GA) in pulmonary vein isolation (PVI) is associated with a lower recurrence rate of atrial fibrillation (AF). GA may improve catheter stability and mapping system accuracy compared to CS, but its influence on contact force (CF) parameters during ipsil...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-017-0961-z
更新日期:2017-08-01 00:00:00
abstract::The inotropic effects of 5-hydroxytryptamine (5-HT) on mammalian heart muscles were investigated. 5-HT (10(-8)-10(-3)M) produced increases in the contractile tension of atrial and ventricular muscles isolated from guinea pigs, Japanese monkeys, and humans, but not in rat heart preparations. The maximum percent increas...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/BF01744594
更新日期:1996-01-01 00:00:00
abstract::Soluble urokinase-type plasminogen activator receptor (suPAR) is a membrane-binding protein that is released into the blood stream by immune activation. Recent reports suggest that circulating suPAR levels are associated with adverse cardiovascular outcomes. Exercise tolerance is an independent predictor of prognosis ...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-019-01538-3
更新日期:2020-05-01 00:00:00
abstract::In order to clarify the pathogenesis of acute myocardial infarction (MI) in hearts with normal coronary arteries, infarct size, and the extent of contraction band necrosis (CBN), coagulation necrosis, and hemorrhage were quantitatively examined using an image analyzer in 5 autopsy cases of MI with normal or nearly nor...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/BF02301880
更新日期:1990-01-01 00:00:00
abstract::The records of 153 patients with doubly committed subarterial ventricular septal defect (DCVSD) who underwent intracardiac repair were analyzed to evaluate factors responsible for aortic valve leaflet deformity. The patients were divided into two groups according to their echocardiographic and angiographic features as...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/BF01747853
更新日期:1999-01-01 00:00:00
abstract::Hyperuricemia is common in chronic kidney disease (CKD), but data regarding the relationship between serum uric acid levels and the long-term outcomes of CKD patients have been limited. The present study evaluated the associations between baseline serum uric acid levels with mortality and end-stage renal disease (ESRD...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-013-0396-0
更新日期:2014-07-01 00:00:00
abstract::Even though drug-coated balloon (DCB) angioplasty has emerged as a treatment option for drug-eluting stent in-stent restenosis (DES-ISR), the most effective treatment strategy for DES-ISR is still under debate. Therefore, we compared long-term clinical outcomes following DCB treatment of DES-ISR with those following 2...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-015-0741-6
更新日期:2016-09-01 00:00:00