Abstract:
:Temperature control of hyperthermia treatments is generally implemented with multipoint feedback system comprised of phased-array transducer, which is complicated and high cost. Our simulations to the acoustic field induced by a self-focused concave spherical transducer (0.5MHz, 9cm aperture width, 8.0cm focal length) show that the distribution of temperature can keep the same "cigar shape" in the focal region during ultrasound insonation. Based on the characteristic of the temperature change, a two-dimensional model of a "cigar shape" tumor is designed and tested through numerical simulation. One single-point on the border of the "cigar shape" tumor is selected as the control target and is controlled at the temperature of 43 degrees C by using a self-tuning regulator (STR). Considering the nonlinear effects of biological medium, an accurate state-space model obtained via the finite Fourier integral transformation to the bioheat equation is presented and used for calculating temperature. Computer simulations were performed with the perfusion rates of 2.0kg/(m(3)s) and 4.5kg/(m(3)s) to the different targets, it was found that the temperatures on the border of the "cigar shape" tumor can achieve the desired temperature of 43 degrees C by control of one single-point. A larger perfusion rate requires a higher power output to obtain the same temperature elevation under the same insonation time and needs a higher cost for compensating the energy loss carried away by blood flow after steady state. The power output increases with the controlled region while achieving the same temperature at the same time. Especially, there is no overshoot during temperature elevation and no oscillation after steady state. The simulation results demonstrate that the proposed approach may offers a way for obtaining a single-point, low-cost hyperthermia system.
journal_name
Ultrasonicsjournal_title
Ultrasonicsauthors
Hu J,Qian S,Ding Ydoi
10.1016/j.ultras.2010.01.006subject
Has Abstractpub_date
2010-05-01 00:00:00pages
628-33issue
6eissn
0041-624Xissn
1874-9968pii
S0041-624X(10)00019-3journal_volume
50pub_type
杂志文章相关文献
ULTRASONICS文献大全abstract::A method for measuring the mechanical quality factor (Q factor) of materials in large-amplitude flexural vibrations was devised on the basis of the original definition of the Q factor. The Q factor, the ratio of the reactive energy to the dissipated energy, was calculated from the vibration velocity distribution. The ...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/j.ultras.2016.03.012
更新日期:2016-07-01 00:00:00
abstract::The present study focuses on a possibility for improving NO removal efficiency from flue gas by application of powerful sound waves. The sound waves (frequency 6.9-17.2kHz, intensity 144-160dB) are propagated from Hartmann sound generators to a preheated graphite disk inside a vertical reaction tube (height 1.8m, I.D....
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/j.ultras.2004.06.010
更新日期:2005-02-01 00:00:00
abstract::In this paper, we propose a semi-analytical isogeometric analysis(S-IGA) approach in the twist space to investigate the dispersive properties in helical thread waveguides, which combines the advantages of the spectral approach and IGA. The convergence and accuracy of the proposed method are discussed, by comparing S-I...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/j.ultras.2017.06.004
更新日期:2018-02-01 00:00:00
abstract::In this paper, a new topological structure for the Langevin-type ultrasonic transducer is proposed and investigated. The two cylindrical terminal blocks are conically shaped with four supporting plates each, and two cooling fins are disposed at the bottom of terminal blocks, adjacent to the piezoelectric rings. Experi...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/j.ultras.2016.11.008
更新日期:2017-03-01 00:00:00
abstract::We demonstrate a new method for a real-time imaging of surface acoustic waves at frequencies up to 1 GHz with picosecond temporal and micron spatial resolutions using an ultrafast optical pump and probe technique combined with a common path interferometer. Using samples with isotropic or anisotropic substrates coated ...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/s0041-624x(02)00090-2
更新日期:2002-05-01 00:00:00
abstract::Surface wave motions generated by a time-harmonic point load applied at the surface of an isotropic linearly elastic half-space are conventionally solved by the use of integral transform techniques. The inverse transforms, are often complicated and will not always yield closed-form solutions. In this paper expressions...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/j.ultras.2014.05.003
更新日期:2014-09-01 00:00:00
abstract::It is now accepted that an effective way to investigate the elastic properties of soft tissues is to generate a localized transient acoustic radiation force and to follow the associated displacements in the time/space domain. Shear waves induced by this stress field are particularly interesting in this kind of medium ...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/j.ultras.2006.06.022
更新日期:2006-12-22 00:00:00
abstract::A novel nanocomposite-inspired in-situ broadband ultrasonic sensor previously developed, with carbon black as the nanofiller and polyvinylidene fluoride as the matrix, was networked for acousto-ultrasonic wave-based passive and active structural health monitoring (SHM). Being lightweight and small, this kind of sensor...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/j.ultras.2017.03.007
更新日期:2017-07-01 00:00:00
abstract::Thrombosis is an extremely critical clinical condition where a clot forms inside a blood vessel which blocks the blood flow through the cardiovascular system. Previous sonothrombolysis methods using ultrasound and microbubbles (MBs) often have a relatively low lysis rate due to the low microbubbles concentration at cl...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/j.ultras.2019.06.004
更新日期:2019-09-01 00:00:00
abstract:MOTIVATION:Commercial ultrasound machines in the past did not provide the ultrasound researchers access to raw ultrasound data. Lack of this ability has impeded evaluation and clinical testing of novel ultrasound algorithms and applications. OBJECTIVES:Recently, we developed a flexible ultrasound back-end where all th...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/j.ultras.2007.11.009
更新日期:2008-07-01 00:00:00
abstract::Ultrasound image guided brain surgery (UGBS) requires an automatic and fast image segmentation method. The level-set and active contour based algorithms have been found to be useful for obtaining topology-independent boundaries between different image regions. But slow convergence limits their use in online US image s...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/j.ultras.2020.106304
更新日期:2021-03-01 00:00:00
abstract::The electromagnetic acoustic transducers (EMATs) with a meander-line coil possess the capability of generating Lamb waves carrying multiple wavelengths, and the characteristics of multiple wavelengths is analyzed by developing a spatial transversal filter model for the EMAT. It is shown that the characteristics is due...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/j.ultras.2013.09.003
更新日期:2014-02-01 00:00:00
abstract::Classically, rotary motors with gears and spindle mechanisms are used to achieve translatory motion. In means of miniaturization and weight reduction piezoelectric linear motors are of interest. Several ultrasonic linear motors found in literature base on the use of two different vibration modes. Most often flexural a...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/j.ultras.2006.05.056
更新日期:2006-12-22 00:00:00
abstract::Mechanical properties of biological tissue represent important diagnostic information and are of histological and pathological relevance. In order to obtain non-invasively mechanical properties of tissue, we developed a real-time strain imaging system for clinical applications. The output data of this system also allo...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/j.ultras.2006.06.007
更新日期:2006-12-22 00:00:00
abstract::In this paper, high-speed photography was used to investigate the intrinsic dynamics of subharmonious surface wave in a vertical vibrated and idealized bidimensional granular layer. Using the high-speed photography, velocity fields of the granular layer at different stages through two cycles were obtained, which show ...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/j.ultras.2006.05.196
更新日期:2006-12-22 00:00:00
abstract::A nonlinear ultrasonic method is proposed based on a group of newly discovered wave triplets where two primary codirectional shear-horizontal SH0 waves mix in a weakly nonlinear plate and generate a cumulative S0 Lamb wave at the sum frequency. Theoretical analyses show that any combination of two primary SH0 waves wh...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/j.ultras.2019.04.001
更新日期:2019-07-01 00:00:00
abstract::Thallium bromide iodide crystal also known as KRS-5 is the well known material used in far infrared radiation applications for optical windows and lenses fabrication. The main advantage of this material is the transparency in wide band of wavelengths from 0.53 to 50μm. Despite such advantages as transparency and large...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/j.ultras.2016.11.019
更新日期:2017-03-01 00:00:00
abstract::Guided acoustic waves, such as Lamb waves, are widely applied for material characterization, sensing of liquids and the generation of streaming in liquids. There are numerical simulation tools for the prediction of their propagation near a solid-liquid boundary but a demand for complementary measurement techniques for...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/j.ultras.2019.105955
更新日期:2019-11-01 00:00:00
abstract::The ultrasound-induced harmonic microbubble response spectrum is known to shift to lower frequencies with increasing tissue attenuation. We hypothesized that this shift could be reproducibly detected in received broadband radiofrequency spectra. We used an automatic Gaussian curve-fitting technique to measure the mean...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/s0041-624x(02)00397-9
更新日期:2003-03-01 00:00:00
abstract::A new method of spatial compound imaging is presented that improves image quality without the usual requirement to decrease the frame rate. The new method of imaging utilizes three transducers for data acquisition. The transducer located at the center of the transducer system is a phased array probe that acts as both ...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/s0041-624x(03)00105-7
更新日期:2003-07-01 00:00:00
abstract::The natural frequencies and distributions of displacement components for the surface vibrational modes in thin isotropic elastic disks are calculated. In particular, the research is focused on even solutions for low-lying resonant vibrations with large angular wave numbers. Several families of modes are found which ar...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/j.ultras.2013.11.002
更新日期:2014-03-01 00:00:00
abstract::In this study, 3D finite element simulation of ultrasonically-assisted drilling is carried out to analyze the effect of ultrasonic vibrations on common difficulties existed in conventional drilling. Influence of harmonic movement of drill bit on the formation of built-up edge is experimentally evaluated and also discu...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/j.ultras.2016.11.009
更新日期:2017-03-01 00:00:00
abstract::In this newly developed method, the ultrasonic diagnosis has become quantitative. The data will remain quantitative so far as an image storage tube is used. With the conventional storage type CRT, it is impossible to memorize the reflected echo signals of different strength levels. But with our method, it becomes poss...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/0041-624x(75)90036-0
更新日期:1975-09-01 00:00:00
abstract::We study thickness-shear vibration of a quartz plate connected to two piezoelectric ceramic plates with initial deformations caused by a biasing electric field. The theory for small deformations superposed on finite biasing deformations in an electroelastic body is used. It is shown that the resonant frequencies of th...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/j.ultras.2010.07.002
更新日期:2011-02-01 00:00:00
abstract::Targeted mechanical cell stimulation has been extensively studied for a better understanding of its effect on cellular mechanotransduction signaling pathways and structures by utilizing a variety of mechanical sources. In this work, an ultrasound-driven single cell stimulation method is thus proposed, and a preliminar...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/j.ultras.2012.03.002
更新日期:2012-09-01 00:00:00
abstract::This paper describes a completely non-contact ultrasonic method of gas flow metering using air-coupled leaky Lamb waves. To show proof of principle, a simplified representation of gas flow in a duct, comprising two separated thin isotropic plates with a gas flowing between them, has been modelled and investigated expe...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/j.ultras.2018.04.008
更新日期:2018-09-01 00:00:00
abstract::The frequency dependence of H2O2 generation from H2O by a sonochemical reaction was detected experimentally. The results are in good agreement with previous experimental results, which indicate that in sonochemical reactions, frequencies higher than 90 kHz are more effective than frequencies of several tens of kiloher...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/s0041-624x(99)00114-6
更新日期:2000-03-01 00:00:00
abstract::A reformulation of the Thomson-Haskell method is presented for calculating the reflection coefficients of multilayer structure immersing in the coupling fluid. Instead of directly multiplying the layer propagator matrix, the new method splits the layer propagator matrix and excursively determines the interface stiffne...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/j.ultras.2012.08.004
更新日期:2012-12-01 00:00:00
abstract::High-frequency calibration of hydrophones is becoming increasingly important, both for clinical and scientific applications of ultrasound, and user safety. At present, the calibrations available routinely to the user community extend to 60 MHz. However, hydrophones that can measure beyond this are available, and ultra...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/j.ultras.2020.106218
更新日期:2020-12-01 00:00:00
abstract::Since the identification of micro-cracks in engineering materials is very valuable in understanding the initial and slight changes in mechanical properties of materials under complex working environments, numerical simulations on the propagation of the low frequency S0 Lamb wave in thin plates with randomly distribute...
journal_title:Ultrasonics
pub_type: 杂志文章
doi:10.1016/j.ultras.2017.04.004
更新日期:2017-08-01 00:00:00