Splicing and transcription differ between spore and intracellular life stages in the parasitic microsporidia.

abstract：:Multiple haplotypes from each of three nuclear loci were isolated and sequenced from geographic populations of the American oyster, Crassostrea virginica. In tests of alternative phylogeographic hypotheses for this species, nuclear gene genealogies constructed for these haplotypes were compared to one another, to a mi...

journal_title：Molecular biology and evolution

authors： Hare MP,Avise JC

更新日期：1998-02-01 00:00:00

abstract：:The detection of selection, both positive and negative, acting on a DNA sequence or class of nucleotide sites requires comparison with a reference sequence that is unaffected by selection. In Drosophila, recent findings of widespread selective constraint, as well as adaptive evolution, in both coding and noncoding reg...

journal_title：Molecular biology and evolution

authors： Parsch J,Novozhilov S,Saminadin-Peter SS,Wong KM,Andolfatto P

更新日期：2010-06-01 00:00:00

abstract：:Evolution at silent sites is often used to estimate the pace of selectively neutral processes or to infer differences in divergence times of genes. However, silent sites are subject to selection in favor of preferred codons, and the strength of such selection varies dramatically across genes. Here, we use the relation...

journal_title：Molecular biology and evolution

authors： Hirsh AE,Fraser HB,Wall DP

更新日期：2005-01-01 00:00:00

abstract：:Protamines are small, highly basic DNA-binding proteins found in the sperm of animals. Interestingly, the proportion of arginine residues in one type of protamine, protamine P1, is about 50% in mammals. Upon closer examination, it was found that both the total number of amino acids and the positions of arginine residu...

journal_title：Molecular biology and evolution

authors： Rooney AP,Zhang J,Nei M

更新日期：2000-02-01 00:00:00

abstract：:Random genetic drift, or stochastic change in gene frequency, is a fundamental evolutionary force that is usually defined within the ideal Wright-Fisher (WF) population. However, as the theory is increasingly applied to populations that deviate strongly from the ideal model, a paradox of random drift has emerged. When...

journal_title：Molecular biology and evolution

authors： Chen Y,Tong D,Wu CI

更新日期：2017-08-01 00:00:00

abstract：:The T1 family of retrotransposable elements is interspersed and moderately repeated in five member species of the Anopheles gambiae sibling-species complex and has diverged little since the radiation of the complex. T1 includes two closely related but independent subfamilies, defined by the presence or absence of link...

journal_title：Molecular biology and evolution

authors： Besansky NJ

更新日期：1990-05-01 00:00:00

abstract：:Ion channels have played a substantial role in the evolution of novel traits across all of the domains of life. A fascinating example of a novel adaptation is the convergent evolution of electric organs in the Mormyroid and Gymnotiform electric fishes. The regulated currents that flow through ion channels directly gen...

journal_title：Molecular biology and evolution

authors： Thompson A,Vo D,Comfort C,Zakon HH

更新日期：2014-08-01 00:00:00

abstract：:As the largest European herbivore, the wisent (Bison bonasus) is emblematic of the continent wildlife but has unclear origins. Here, we infer its demographic and adaptive histories from two individual whole-genome sequences via a detailed comparative analysis with bovine genomes. We estimate that the wisent and bovine...

journal_title：Molecular biology and evolution

authors： Gautier M,Moazami-Goudarzi K,Levéziel H,Parinello H,Grohs C,Rialle S,Kowalczyk R,Flori L

更新日期：2016-11-01 00:00:00

abstract：:Homologues of glucosephosphate isomerase (GPI, EC 5.3.1.9) were purified to homogeneity and kinetically characterized from Mytilus edulis and Isognomon alatus, two bivalve molluscs experiencing contrasting thermal environments. The enzyme isolated from I. alatus functions at warmer temperatures (25-35 C) than GPI from...

journal_title：Molecular biology and evolution

authors： Hall JG

更新日期：1985-05-01 00:00:00

abstract：:Whole genome duplications (WGDs) have been hypothesized to be responsible for major transitions in evolution. However, the effects of WGD and subsequent gene loss on cellular behavior and metabolism are still poorly understood. Here we develop a genome scale evolutionary model to study the dynamics of gene loss and me...

journal_title：Molecular biology and evolution

authors： van Hoek MJ,Hogeweg P

更新日期：2009-11-01 00:00:00

abstract：:Hybrid males resulting from crosses between closely related species of Drosophila are sterile. The F1 hybrid sterility phenotype is mainly due to defects occurring during late stages of development that relate to sperm individualization, and so genes controlling sperm development may have been subjected to selective d...

journal_title：Molecular biology and evolution

authors： Civetta A,Rajakumar SA,Brouwers B,Bacik JP

更新日期：2006-03-01 00:00:00

abstract：:We have used analysis of variance to partition the variation in synonymous and amino acid substitution rates between three effects (gene, lineage, and a gene-by-lineage interaction) in mammalian nuclear and mitochondrial genes. We find that gene effects are stronger for amino acid substitution rates than for synonymou...

journal_title：Molecular biology and evolution

authors： Smith NG,Eyre-Walker A

更新日期：2003-01-01 00:00:00

abstract：:Due to its speed, the distance approach remains the best hope for building phylogenies on very large sets of taxa. Recently (R. Desper and O. Gascuel, J. Comp. Biol. 9:687-705, 2002), we introduced a new "balanced" minimum evolution (BME) principle, based on a branch length estimation scheme of Y. Pauplin (J. Mol. Evo...

journal_title：Molecular biology and evolution

authors： Desper R,Gascuel O

更新日期：2004-03-01 00:00:00

abstract：:We measured nucleotide variability within and between the three semispecies of the Drosophila athabasca complex, at the period (per) gene by using a polymerase chain reaction-based four-cutter restriction-enzyme analysis. The levels of polymorphism varied considerably between the three semispecies. Our results for per...

journal_title：Molecular biology and evolution

authors： Ford MJ,Yoon CK,Aquadro CF

更新日期：1994-03-01 00:00:00

abstract：:Reconstructing phylogenies from intraspecific data (such as human mitochondrial DNA variation) is often a challenging task because of large sample sizes and small genetic distances between individuals. The resulting multitude of plausible trees is best expressed by a network which displays alternative potential evolut...

journal_title：Molecular biology and evolution

authors： Bandelt HJ,Forster P,Röhl A

更新日期：1999-01-01 00:00:00

abstract：:The quantitative immunological technique of micro-complement fixation (MC'F) has been routinely used during the past decade to assess evolutionary relationships among living vertebrate species. The large data base that has been generated, along with the excellent correlations between immunologically measured genetic d...

journal_title：Molecular biology and evolution

authors： Maxson RD,Maxson LR

更新日期：1986-09-01 00:00:00

abstract：:Genetic incompatibilities are commonly observed between hybridizing species. Although this type of isolating mechanism has received considerable attention, we have few examples describing how genetic incompatibilities evolve. We investigated the evolution of two loci involved in a classic example of a Bateson-Dobzhans...

journal_title：Molecular biology and evolution

authors： Scarpino SV,Hunt PJ,Garcia-De-Leon FJ,Juenger TE,Schartl M,Kirkpatrick M

更新日期：2013-10-01 00:00:00

abstract：:The mitoribosome, as known from studies in model organisms, deviates considerably from its ancestor, the bacterial ribosome. Deviations include substantial reduction of the mitochondrial ribosomal RNA (mt-rRNA) structure and acquisition of numerous mitochondrion-specific (M) mitoribosomal proteins (mtRPs). A broadly a...

journal_title：Molecular biology and evolution

authors： Valach M,Alcazar JAG,Sarrasin M,Lang BF,Gray MW,Burger G

更新日期：2020-09-04 00:00:00

abstract：:Sponges (Porifera) are among the simplest living and the earliest branching metazoans. They hold a pivotal role for studying genome evolution of the entire metazoan branch, both as an outgroup to Eumetazoa and as the closest branching phylum to the common ancestor of all multicellular animals (Urmetazoa). In order to ...

journal_title：Molecular biology and evolution

authors： Harcet M,Roller M,Cetković H,Perina D,Wiens M,Müller WE,Vlahovicek K

更新日期：2010-12-01 00:00:00

abstract：:Baleen whales (suborder Mysticeti) comprise 11 extant species that are classified into four families. Although several phylogenetic hypotheses about these taxa have been proposed, their phylogenetic relationships remain confused. We addressed this problem using short interspersed repetitive element (SINE) insertion da...

journal_title：Molecular biology and evolution

authors： Nikaido M,Hamilton H,Makino H,Sasaki T,Takahashi K,Goto M,Kanda N,Pastene LA,Okada N,SMBE Tri-National Young Investigators.

更新日期：2006-05-01 00:00:00

abstract：:Knowledge of mutation rates is crucial for calibrating population genetics models of demographic history in units of years. However, mutation rates remain challenging to estimate because of the need to identify extremely rare events. We estimated the nuclear mutation rate in wolves by identifying de novo mutations in ...

journal_title：Molecular biology and evolution

authors： Koch E,Schweizer RM,Schweizer TM,Stahler DR,Smith DW,Wayne RK,Novembre J

更新日期：2019-07-12 00:00:00

abstract：:We examine rate heterogeneity among evolutionary lineages of the grass family at two plasmid loci, ndhF and rbcL, and we introduce a method to determine whether patterns of rate heterogeneity are correlated between loci. We show both that rates of synonymous evolution are heterogeneous among grass lineages and that ar...

journal_title：Molecular biology and evolution

authors： Gaut BS,Clark LG,Wendel JF,Muse SV

更新日期：1997-07-01 00:00:00

abstract：:Vertebrate eye lenses mostly contain two abundant types of proteins, the alpha-crystallins and the beta/gamma-crystallins. In addition, certain housekeeping enzymes are highly expressed as crystallins in various taxa. We now observed an unusual approximately 41-kd protein that makes up 16% to 18% of the total protein ...

journal_title：Molecular biology and evolution

authors： van Rheede T,Amons R,Stewart N,de Jong WW

更新日期：2003-06-01 00:00:00

abstract：:Wolbachia bacteria infect about half of all arthropods, with diverse and extreme consequences ranging from sex-ratio distortion and mating incompatibilities to protection against viruses. These phenotypic effects, combined with efficient vertical transmission from mothers to offspring, satisfactorily explain the invas...

journal_title：Molecular biology and evolution

authors： Bailly-Bechet M,Martins-Simões P,Szöllosi GJ,Mialdea G,Sagot MF,Charlat S

更新日期：2017-05-01 00:00:00

abstract：:Natural selection is expected to act strongly on immune system genes as hosts adapt to novel, diverse, and coevolving pathogens. Population genetic studies of host defense genes with parallel functions in model organisms have revealed distinct evolutionary histories among the different components-receptors, adaptors, ...

journal_title：Molecular biology and evolution

authors： Fornarino S,Laval G,Barreiro LB,Manry J,Vasseur E,Quintana-Murci L

更新日期：2011-11-01 00:00:00

abstract：:DNA fingerprinting exhibits multilocus genotypes of individuals, detected by the use of a single multilocus probe. Consequently, population data on DNA fingerprinting do not provide a complete characterization of the genetic variation in terms of allele-frequency distributions, since neither the number of loci nor the...

journal_title：Molecular biology and evolution

authors： Jin L,Chakraborty R

更新日期：1994-01-01 00:00:00

abstract：:Most mitochondrial proteins are synthesized in the cytosol of eukaryotic cells as precursor proteins carrying N-terminal extensions called transit peptides or presequences, which mediate their specific transport into mitochondria. However, plant cells possess a second potential target organelle for such transit peptid...

journal_title：Molecular biology and evolution

authors： Staiger C,Hinneburg A,Klösgen RB

更新日期：2009-08-01 00:00:00

abstract：:Male reproductive fitness is strongly affected by seminal fluid. In addition to interacting with the female environment, seminal fluid mediates important physiological characteristics of sperm, including capacitation and motility. In mammals, the male reproductive tract shows a striking degree of compartmentalization,...

journal_title：Molecular biology and evolution

authors： Dean MD,Clark NL,Findlay GD,Karn RC,Yi X,Swanson WJ,MacCoss MJ,Nachman MW

更新日期：2009-08-01 00:00:00

abstract：:As the oomycete pathogen causing potato late blight disease, Phytophthora infestans triggered the famous 19th-century Irish potato famine and remains the leading cause of global commercial potato crop destruction. But the geographic origin of the genotype that caused this devastating initial outbreak remains disputed,...

journal_title：Molecular biology and evolution

authors： Martin MD,Vieira FG,Ho SY,Wales N,Schubert M,Seguin-Orlando A,Ristaino JB,Gilbert MT

更新日期：2016-02-01 00:00:00

abstract：:Members of the grass family (Poaceae) exhibit a broad range of inflorescence structures and other morphologies, making the grasses an interesting model system for studying the evolution of development. Here we present an analysis of the molecular evolution of FLORICAULA/LEAFY-like genes, which are important developmen...

journal_title：Molecular biology and evolution

authors： Bomblies K,Doebley JF

更新日期：2005-04-01 00:00:00