Stimulation by D-glucose of protein biosynthesis in tumoral insulin-producing cells (RINm5F line).

abstract：:The existence of a vasoactive molecule released in response to hCG is believed to be the main feature in the development of ovarian hyperstimulation syndrome (OHSS) in women, and vascular endothelial growth factor (VEGF) is the main candidate as the human chorionic gonadotropin (hCG) mediator. This study was conducted...

journal_title：Endocrinology

authors： Gómez R,Simón C,Remohí J,Pellicer A

更新日期：2002-11-01 00:00:00

abstract：:GnRH, the main regulator of reproduction, is produced in a variety of tissues outside of the hypothalamus, its main site of synthesis and release. We aimed to determine whether GnRH produced in the female rat pituitary and ovaries is involved in the processes leading to ovulation. We studied the expression patterns of...

journal_title：Endocrinology

authors： Schirman-Hildesheim TD,Bar T,Ben-Aroya N,Koch Y

更新日期：2005-08-01 00:00:00

abstract：:The guinea pig is unusual in that its postnatal growth appears to be independent of GH even though its pituitary gland produces a GH molecule. The effects of fasting on the GH secretory pattern and the GH responses to insulin, GH-releasing factor (GRF), and somatostatin (SS) during fasting have now been studied by aut...

journal_title：Endocrinology

authors： Fairhall KM,Gabrielsson BG,Robinson IC

更新日期：1990-08-01 00:00:00

abstract：:The influence of LY117018 and tamoxifen on established uterotropic influence of estradiol was examined in immature ovariectomized rats. When LY117018 was introduced on the fourth day of estradiol treatment, it regressed the uterotropic effect of estradiol. However, tamoxifen did not attenuate estradiol activity under ...

journal_title：Endocrinology

authors： Black LJ,Goode RL

更新日期：1981-09-01 00:00:00

abstract：:Pituitary glands from ovariectomized F-344 rats bearing diethylstilbestrol-containing capsules for 70-100 days were dissociated and separated into three size classes by unit gravity sedimentation. The average percentage of large mammotrophs in fraction I was 86 +/- (SE) 2%, the percentage of intermediate-sized mammotr...

journal_title：Endocrinology

authors： Hymer WC,Motter KA

更新日期：1988-05-01 00:00:00

abstract：:The antral hormone gastrin and its intestinal relative, cholecystokinin (CCK), are pivotal in the regulation of gastric functions. Other gastric hormones like ghrelin, peptide YY (PYY), and islet amyloid polypeptide (IAPP), however, also contribute to the regulation of acid secretion, motility, and feeding. Because ga...

journal_title：Endocrinology

authors： Friis-Hansen L,Wierup N,Rehfeld JF,Sundler F

更新日期：2005-10-01 00:00:00

abstract：:An in vitro system which uses perifused pieces from the antrum of rat stomach has been used to study the effect of dihydrosomatostatin on gastrin release. The gastrin concentration in fractions of the perfusate was measured by radioimmunoassay. Dihydrosomatostatin (2 x 10-7M) had no effect on basal gastrin levels but ...

journal_title：Endocrinology

authors： Hayes JR,Johnson DG,Koerker D,Williams RH

更新日期：1975-06-01 00:00:00

abstract：:Glucocorticoid (Gc) excess, from endogenous overproduction in disorders of the hypothalamic-pituitary-adrenal axis or exogenous medical therapy, is recognized to cause adverse metabolic side effects. The Gc receptor (GR) is widely expressed throughout the body, including brain regions such as the hypothalamus. However...

journal_title：Endocrinology

authors： Sefton C,Harno E,Davies A,Small H,Allen TJ,Wray JR,Lawrence CB,Coll AP,White A

更新日期：2016-11-01 00:00:00

abstract：:The physicochemical and immunological properties of androgen receptors from kidney and brain of testicular-feminized (Tfm) mutant mice and wild-type mice were compared. Analysis by gel filtration and sucrose density gradients revealed that the mol wt of the mutant receptor was 66K (38A; 3.8S) which was significantly s...

journal_title：Endocrinology

authors： Young CY,Johnson MP,Prescott JL,Tindall DJ

更新日期：1989-02-01 00:00:00

abstract：:Steady state levels of plasma membrane receptors (measured in radioligand assays) result from processes that contribute to the production of receptors (synthesis, recycling, and unmasking) as well as those that contribute to the loss of receptors (degradation, internalization, and inactivation). Accordingly, we have p...

journal_title：Endocrinology

authors： Braden TD,Conn PM

更新日期：1990-05-01 00:00:00

abstract：:The intermediary role of the putative inhibitory regulatory membrane protein "Ni" in the "antigonadal" activity of the neurohypophysial hormones was investigated in vitro with the use of a primary culture of rat testicular cells. To this end, use was made of the pertussis toxin (PT) probe, an exotoxin of Bordetella pe...

journal_title：Endocrinology

authors： Adashi EY,Resnick CE,Cronin MJ,Hewlett EL

更新日期：1984-08-01 00:00:00

abstract：:Binding of lactogenic hormones to particulate and solubilized microsomal membranes isolated from mammary glands of lactating mice is inhibited by direct addition of 10(-10) M or greater concentrations of triphenylethylene antiestrogens [i.e. tamoxifen (TAM), 4-hydroxy-tamoxifen, and Nafoxidine] to the binding assays. ...

journal_title：Endocrinology

authors： Biswas R,Vonderhaar BK

更新日期：1991-01-01 00:00:00

abstract：:Basal or hypothalamic extract-induced ACTH or TSH secretory capacity as well as intracellular ACTH content were assessed in cultured rat adenohypophyseal cells after various pretreatments of the donor animals. Medium and intracellular ACTH or TSH were measured by radioimmunoassay. Ten-day to 2-month adrenalectomy enha...

journal_title：Endocrinology

authors： Yasuda N,Takebe K,Greer MA

更新日期：1976-03-01 00:00:00

abstract：:cAMP has been shown to mediate the response of the parathyroid gland to a number of agonists and appears to take part in the regulation of this gland by divalent cations as well. We have studied the effects of the concentrations of free magnesium (Mg+2) and ionic calcium (Ca+2) on the kinetic properties of normal porc...

journal_title：Endocrinology

authors： Oldham SB,Rude RK,Molloy CT,Lipson LG

更新日期：1984-11-01 00:00:00

abstract：:We examined the effects of bombesin on rat pancreatic digestive enzyme gene expression using cloned complementary DNA probes for amylase, trypsinogen I, chymotrypsinogen B, and lysophospholipase. Rats were injected sc three times daily with 5 nmol/kg body wt bombesin. Pancreata were investigated after 6, 12, 24, 48, a...

journal_title：Endocrinology

authors： Rosewicz S,Liehr RM,Solomon TE,Riecken EO,Logsdon CD

更新日期：1992-03-01 00:00:00

abstract：:In the present work a chimeric receptor containing the intracellular domain of the insulin receptor-related receptor (IRR) and the extracellular domain of the colony stimulating factor-1 (CSF-1) receptor was expressed in 3T3-L1 adipocytes and compared with the parallel chimeric receptor containing the cytoplasmic doma...

journal_title：Endocrinology

authors： Dandekar AA,Wallach BJ,Barthel A,Roth RA

更新日期：1998-08-01 00:00:00

abstract：:The role of anti-Müllerian hormone (AMH) during gonad development has been studied extensively in many species of mammal, bird, reptile, and fish but remains unresolved in amphibians. In male mammalian embryos, Sox9 activates AMH expression, which initiates regression of the Müllerian ducts. However, Sox9 (Sry-related...

journal_title：Endocrinology

authors： Kodama M,Suda M,Sakamoto D,Iwasaki T,Matsuo Y,Uno Y,Matsuda Y,Nakamura Y,Maekawa S,Katsu Y,Nakamura M

更新日期：2015-05-01 00:00:00

abstract：:PRL gene expression in the anterior pituitary has been the focus of intensive investigation for many years, but very little information is available on the actual dynamics by which this process occurs in individual mammotrope cells. Here, we used single cell bioluminescent imaging microscopy and a recently refined rep...

journal_title：Endocrinology

authors： Shorte SL,Leclerc GM,Vazquez-Martinez R,Leaumont DC,Faught WJ,Frawley LS,Boockfor FR

更新日期：2002-03-01 00:00:00

abstract：:The effects of endothelin-1 (ET) on several tissues are mediated by prostaglandins. In this study, we investigated the actions of ET on bone and determined whether they are mediated through prostaglandin-dependent pathways. Bone resorption, collagen, and non-collagen protein synthesis and inositol phosphate (IP) produ...

journal_title：Endocrinology

authors： Tatrai A,Foster S,Lakatos P,Shankar G,Stern PH

更新日期：1992-08-01 00:00:00

abstract：:The effects of electrical stimulation of the brain on the ovarian venous plasma concentrations of estradiol (E2) and progesterone (P) were investigated in female rats hypophysectomized and adrenalectomized at 1000 h on the day of proestrus. Stimulation was applied during the proestrous critical period under pentobarbi...

journal_title：Endocrinology

authors： Kawakami M,Kubo K,Uemura T,Nagase M,Hayashi R

更新日期：1981-07-01 00:00:00

abstract：:GH promotes the conversion of cultured preadipose 3T3 cells into adipose cells. The serum of most animals also promotes this differentiation. In order to determine the extent to which GH is responsible for the adipogenic activity of serum, we used a specific antiserum able to suppress completely the adipogenic activit...

journal_title：Endocrinology

authors： Nixon T,Green H

更新日期：1984-02-01 00:00:00

abstract：:Various hormones and growth factors act at least in part by raising the cytosolic pH of the target cell. In the present studies we examined the influence of the muscarinic cholinergic agonist carbachol on intracellular pH (pHi) in chicken granulosa cells. The pHi in granulosa cells from the two largest preovulatory fo...

journal_title：Endocrinology

authors： Li M,Morley P,Schwartz JL,Whitfield JF,Tsang BK

更新日期：1992-07-01 00:00:00

abstract：:Tumor necrosis factor-alpha (TNF), a pleiotropic cytokine localized within the ovary, alters follicular steroidogenesis. Preovulatory follicles dissected from ovaries of normal cyclic adult rats on the morning of proestrus exhibit steroidogenic and histological signs of atresia after 24 h of culture under the conditio...

journal_title：Endocrinology

authors： Roby KF,Terranova PF

更新日期：1990-05-01 00:00:00

abstract：:The effect of 3 alpha-hydroxy-4-pregnen-20-one (3HP), a Sertoli cell steroid, on the secretion of gonadotropins from rat anterior pituitary cells in culture was examined and subsequently compared with the action of other gonadal steroids and steroids structurally related to 3HP. Pituitary cells from randomly cycling, ...

journal_title：Endocrinology

authors： Wood PH,Wiebe JP

更新日期：1989-07-01 00:00:00

abstract：:Synthesis of uteroglobin in rabbit uterine epithelial cells during early pregnancy is induced by progesterone and apparently suppressed by estrogen. To assess whether the steroid hormones exert regulatory effects on the expression of the uteroglobin gene, we performed transcriptional rate assays in endometrial nuclei ...

journal_title：Endocrinology

authors： Shen XZ,Tsai MJ,Bullock DW,Woo SL

更新日期：1983-03-01 00:00:00

abstract：:Transfer of corticosterone from serum to milk was studied in lactating rats after ether and pentobarbital anesthesia. Two minutes after the onset of anesthesia stress, total serum and milk corticosterone concentrations were not significantly different. By 30 min, corticosterone concentrations in serum increased to a p...

journal_title：Endocrinology

authors： Yeh KY

更新日期：1984-10-01 00:00:00

abstract：:Prostacyclin (PGI2) (1-5 micrograms in 3 microliters 0.05 M Tris/HCl buffer, pH 7.5) and its stable metabolite, 6-oxo-PGF1 alpha, were microinjected into the third ventricle of ovariectomized rats, and plasma FSH, GH, PRL, and TSH levels were measured by RIA. Control animals received 3 microliters buffer. Injection of...

journal_title：Endocrinology

authors： Ottlecz A,Samson WK,McCann SM

更新日期：1984-02-01 00:00:00

abstract：:The corpora lutea of pregnancy in the rat are highly dependent on the action of PRL and PRL-like hormones to hypertrophy and to produce progesterone needed for the maintenance of gestation. Two forms of the PRL receptor (PRL-R), designated as long (PRL-RL) and short (PRL-RS), have been described in rat tissues. To det...

journal_title：Endocrinology

authors： Telleria CM,Parmer TG,Zhong L,Clarke DL,Albarracin CT,Duan WR,Linzer DI,Gibori G

更新日期：1997-11-01 00:00:00

abstract：:Studies were carried out to determine the regional central nervous system and species specificity of the previously observed [125I]iodoavian pancreatic polypeptide ( [125I]iodo-APP) specific binding to chick brain membranes. The avian species examined were chicken, pigeon, duck, quail, chukar, and pheasant. In all spe...

journal_title：Endocrinology

authors： Adamo ML,Hazelwood RL

更新日期：1984-03-01 00:00:00

abstract：:Intermittent PTH administration increases bone turnover, resulting in net anabolic effects on bone. These effects are primarily mediated by intracellular cAMP signaling. However, the molecular mechanisms that regulate PTH activity in bone remain incompletely understood. beta-Arrestin2, a G protein-coupled receptor reg...

journal_title：Endocrinology

authors： Ferrari SL,Pierroz DD,Glatt V,Goddard DS,Bianchi EN,Lin FT,Manen D,Bouxsein ML

更新日期：2005-04-01 00:00:00