New enema treatments for inflammatory bowel disease.

abstract：:An 18-year-old male who developed a pancreatic pseudocyst during the active phase of polyarteritis nodosa is described. Cytotoxic therapy with cyclophosphamide and prednisolone was unable to control the manifestation of this disease, and he required percutaneous drainage of the pseudocyst. The drainage resulted in com...

journal_title：Digestive diseases and sciences

authors： Ghosh AK,Sakhuja V,Malik N,Kathuria P,Chugh KS

更新日期：1993-07-01 00:00:00

abstract：:Nearly all chronic anal fissures occur in the posterior midline of the anal canal. However, some of them are in the anterior midline and are rarely double or in the lateral anal walls. The aim of this study was to determine if the clinical, manometric and endosonographic characteristics in patients with chronic anal f...

journal_title：Digestive diseases and sciences

authors： Pascual M,Parés D,Pera M,Courtier R,Gil MJ,Puig S,Serrano A,Andreu M,Grande L

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Usefulness of thiopurine and scheduled infliximab combination therapy in non-immunomodulator (IM)-naïve Crohn's disease (CD) patients and the optimal length of dual therapy are still debated. AIMS:To determine proportion of patients developing disease flare requiring rescue therapy and risk factors associat...

journal_title：Digestive diseases and sciences

authors： Fischer M,Campbell SC,Calley CSJ,Helper DJ,Chiorean MV,Fadda HM

更新日期：2017-11-01 00:00:00

abstract：:Since celiac disease screening by traditional IgA anti-endomysial antibody test is limited by high costs of monkey esophagus commercial kits as well as by rising ethical problems related to the endangered species, the identification of an inexpensive and commonly available substrate for this antibody determination is ...

journal_title：Digestive diseases and sciences

authors： Volta U,Molinaro N,de Franceschi L,Fratangelo D,Bianchi FB

更新日期：1995-09-01 00:00:00

abstract：:Dieulafoy's lesion or cirsoid aneurysm is a rare cause of massive upper gastrointestinal hemorrhage. Historically cirsoid aneurysm most often occurs in the stomach, but has been reported to occur in the jejunum. In this paper, four cases are presented that are felt to represent the first documented cases of cirsoid an...

journal_title：Digestive diseases and sciences

authors： McClave SA,Goldschmid S,Cunningham JT,Boyd WP Jr

更新日期：1988-07-01 00:00:00

abstract：:Several epidemiological studies have demonstrated a close association between Helicobacter pylori infection and carcinoma of the mid- or distal stomach. If this can be shown to be a causal association, eradication of the organism may prevent later development of cancer. Several mechanisms have been proposed by which H...

journal_title：Digestive diseases and sciences

authors： Hahm KB,Lee KJ,Kim JH,Cho SW,Chung MH

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Irritable bowel syndrome (IBS) patients frequently complain of gas-related symptoms, and the lactulose breath test (LBT) is a test that assesses the amount of fermented gas generated by bacteria in the bowel. We aimed to assess the relationship among intestinal gas volume, LBT result, and gastrointe...

journal_title：Digestive diseases and sciences

authors： Youn YH,Park JS,Jahng JH,Lim HC,Kim JH,Pimentel M,Park H,Lee SI

更新日期：2011-07-01 00:00:00

abstract：:The aim of the present study was to study the effect and mechanism of action of intraduodenal and intrajejunal dai-kenchu-to, an herbal medicine clinically effective for uncomplicated postoperative adhesive intestinal obstruction, on upper gastrointestinal motility. Five mongrel dogs were equipped with four strain-gau...

journal_title：Digestive diseases and sciences

authors： Jin XL,Shibata C,Naito H,Ueno T,Funayama Y,Fukushima K,Matsuno S,Sasaki I

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:Heartburn is frequently reported by patients with achalasia before treatment. However, the esophageal sensitivity to acid as a possible mediator of this symptom has not been previously evaluated. AIM:To evaluate the prevalence of gastroesophageal reflux symptoms and the esophageal sensitivity to acid perfus...

journal_title：Digestive diseases and sciences

authors： Ponce J,Ortiz V,Maroto N,Ponce M,Bustamante M,Garrigues V

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Diagnosis of eosinophilic esophagitis (EoE) requires manual quantification of tissue eosinophils. Eosinophil peroxidase (EPX) is an eosinophil-specific, cytoplasmic granule protein released during degranulation. AIMS:The objective of this study was to evaluate image analysis of EPX immunohistochemistry as a...

journal_title：Digestive diseases and sciences

authors： Wright BL,Doyle AD,Shim KP,Pai RK,Barshow SM,Horsley-Silva JL,Luo H,Rank MA,Jacobsen EA,Katzka DA,Kita H,Dellon ES

更新日期：2020-04-04 00:00:00

abstract：:The paraoxonase (PON) genes family maps to chromosome 7q21-q22, within a loci that also showed evidence of susceptibility genes for both Crohn's disease (CD) and ulcerative colitis (UC). In this case-control study we investigated the possible relationship between PON1 and PON2 polymorphisms and the risk of inflammator...

journal_title：Digestive diseases and sciences

authors： Karban A,Hartman C,Eliakim R,Waterman M,Nesher S,Barnett-Griness O,Shamir R

更新日期：2007-10-01 00:00:00

abstract：:There are no requirements concerning the amplitude of simultaneous contractions among the present criteria for the manometric diagnosis of diffuse esophageal spasm. The purpose of this investigation was to determine whether the current criteria effectively identify an appropriately homogenous patient population. Sixty...

journal_title：Digestive diseases and sciences

authors： Allen ML,DiMarino AJ Jr

更新日期：1996-07-01 00:00:00

abstract：:The potential effect of recombinant human interleukin-11 (rhIL-11) on trinitrobenzene sulfonic acid (TNB)-induced colitis was investigated in rats. Intrarectal TNB (40 mg in 0.25 ml 40% ethanol) produced significant ulcerative colitis. The lesions were most severe at three days after TNB instillation, and then decline...

journal_title：Digestive diseases and sciences

authors： Qiu BS,Pfeiffer CJ,Keith JC Jr

更新日期：1996-08-01 00:00:00

abstract：:The effects of cisapride on upper gut motility were studied in seven healthy volunteers by means of a novel intraluminal electromyographic technique in a placebo-controlled study. In the interdigestive state, cisapride (10 mg intravenous bolus injection) markedly increased the number of spike bursts. The most obvious ...

journal_title：Digestive diseases and sciences

authors： Coremans G,Janssens J,Vantrappen G,Chaussade S,Ceccatelli P

更新日期：1988-12-01 00:00:00

abstract：:Consistent regression of intestinal metaplasia in Barrett's esophagus has not been achieved with medical or surgical interventions. In this case report, a patient with Barrett's esophagus of stable length had half the circumference of the Barrett's epithelium ablated with laser therapy while on a high-dose proton-pump...

journal_title：Digestive diseases and sciences

authors： Sampliner RE,Hixson LJ,Fennerty MB,Garewal HS

更新日期：1993-02-01 00:00:00

abstract：:Sera from Japanese patients with chronic liver disease were tested for hepatitis B virus (HBV) markers and antibodies to hepatitis C virus (anti-HCV), and the results were correlated to the presence of hepatocellular carcinoma. In chronic non-A, non-B liver disease, anti-HCV prevalence was high both in patients with h...

journal_title：Digestive diseases and sciences

authors： Yuki N,Hayashi N,Kasahara A,Hagiwara H,Katayama K,Fusamoto H,Kamada T

更新日期：1992-01-01 00:00:00

abstract：:The aim of this study was to evaluate the breath hydrogen test in the diagnosis of small intestine bacterial overgrowth associated with asymptomatic environmental enteropathy in children living in an urban slum. Fifty school-age children living in a slum and 50 children who attended a private health clinic in the same...

journal_title：Digestive diseases and sciences

authors： dos Reis JC,de Morais MB,Oliva CA,Fagundes-Neto U

更新日期：2007-05-01 00:00:00

abstract：:Polycystic liver disease (PCLD) without polycystic kidney is infrequent in clinical setting. Family clustering is found in patients with PCLD, and it is inherited in an autosomal dominant fashion. Through positional cloning in North America and Europe (mostly in Dutch and Finnish descents), mutations in PRKCSH gene on...

journal_title：Digestive diseases and sciences

authors： Yang AM,Shih SC,Chu CH,Wang TE,Yang WS

更新日期：2010-03-01 00:00:00

abstract：:A 70-year-old woman with secretory diarrhea was studied with a novel technique of recording small intestinal myoelectrical activity which allowed us to obtain long, uninterrupted records of slow waves and spikes at eight or more different intestinal levels simultaneously. Typical migrating action potential complexes (...

journal_title：Digestive diseases and sciences

authors： Coremans G,Janssens J,Vantrappen G,Chaussade S,Ceccatelli P

更新日期：1987-10-01 00:00:00

abstract：:The aims of this study were to select the patients with a potential for progression to hepatic failure due to lamivudine-resistant HBV and to standardize the treatment for patients with lamivudine-resistant HBV. Patients (n = 47) with reactivated hepatitis due to lamivudine-resistant HBV were classified into two group...

journal_title：Digestive diseases and sciences

authors： Kuwahara R,Kumashiro R,Ide T,Koga Y,Hino T,Hisamochi A,Tanaka K,Ogata K,Koga H,Takao Y,Sata M

更新日期：2008-11-01 00:00:00

abstract：:Rectally administered suspensions of 5-aminosalicylic acid (5-ASA) are topically effective in treating left-sided ulcerative colitis. The extent to which the contents of these enemas are distributed to inflamed mucosal linings has not previously been determined. This study was undertaken to validate a technique for la...

journal_title：Digestive diseases and sciences

authors： Vitti RA,Meyers F,Knight LC,Siegel JA,Malmud LS,Fisher RS

更新日期：1989-11-01 00:00:00

abstract：:We report the findings in two sisters with active cirrhosis and an anti-liver-kidney microsomal antibody (anti-LKM) of the autoimmune type. This unusual disease is characterized by the presence of high levels of antibodies that react with the smooth and rough endoplasmic reticulum of the liver and other tissues. Our p...

journal_title：Digestive diseases and sciences

authors： Buffet C,Homberg JC,Pelletier G,Turner K,Etienne JP

更新日期：1986-11-01 00:00:00

abstract：:This study was designed to determine the effect of a newly synthesized benzimidazole derivative NC-1300-B on H+, K+-ATPase (proton pump) in the hog gastric mucosa and on the basal gastric acid secretion and necrotizing agent-induced gastric lesions in rats. NC-1300-B inhibited the proton pump in a concentration-depend...

journal_title：Digestive diseases and sciences

authors： Okabe S,Akimoto Y,Yamasaki S,Nagai H

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Probe-based confocal laser endomicroscopy (pCLE) has enabled in vivo histopathology by obtaining high resolution images of the mucosal layers of the gastrointestinal tract. For indeterminate bile duct strictures, biopsy, cytologic brushing and needle aspiration have low levels of diagnostic accuracy. AIM:Th...

journal_title：Digestive diseases and sciences

authors： Talreja JP,Sethi A,Jamidar PA,Singh SK,Kwon RS,Siddiqui UD,Sawhney M,Bakhru MR,Gaidhane M,Kline P,Sauer BG,Kahaleh M

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Average-risk women aged 50-59 years have a lower incidence and mortality of colorectal cancer relative to age-matched men, calling into question the benefit of screening colonoscopy in this age group. AIMS:We aimed to determine whether FOBT is an effective initial screening test in 50-59-year-old women. ME...

journal_title：Digestive diseases and sciences

authors： Mooers HM,Holub JL,Lieberman DA

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVES:Acute pancreatitis (AP) is a severe inflammatory disease with high mortality and morbidity rates. We have previously demonstrated that resistin may represent an early marker of inflammation in AP. It was also revealed that ghrelin may have anti-inflammatory potential. However, the role of adipohormones in AP...

journal_title：Digestive diseases and sciences

authors： Daniel P,Leśniowski B,Jasińska A,Pietruczuk M,Małecka-Panas E

更新日期：2010-10-01 00:00:00

abstract：:It is known that the muscularis mucosae and mucosa are not pharmacologically homogeneous throughout the rat colon. The aim of this study was to simultaneously characterize all three neurokinin (NK) receptors in the muscularis mucosae and mucosa along the length of the rat colon. Strips of proximal, mid, and distal col...

journal_title：Digestive diseases and sciences

authors： Appleyard CB,Morales M,Percy WH

更新日期：2006-03-01 00:00:00

abstract：:Dilation of malignant esophageal strictures often is required to complete staging by endoscopic ultrasound (EUS). This study was designed to determine the successful dilation rate (ability to complete staging) and complication rate of through-the-scope (TTS) balloon dilation for malignant esophageal strictures during ...

journal_title：Digestive diseases and sciences

authors： Jacobson BC,Shami VM,Faigel DO,Larghi A,Kahaleh M,Dye C,Pedrosa M,Waxman I

更新日期：2007-03-01 00:00:00

abstract：:Hepatic vein thrombosis (Budd-Chiari syndrome) is a rare complication of ulcerative colitis and has not previously been reported in association with Crohn's disease. We here report the first known case of Crohn's disease presenting as the Budd-Chiari syndrome. ...

journal_title：Digestive diseases and sciences

authors： Maccini DM,Berg JC,Bell GA

更新日期：1989-12-01 00:00:00

abstract：:A 24-year-old white woman presented with abdominal discomfort associated with a firm, nonpulsatile hepatic mass. Radiological examination, which included radionuclide liver scan, abdominal ultrasonography, computed tomography, and hepatic angiography, demonstrated a large, globular, multilocular cyst arising from the ...

journal_title：Digestive diseases and sciences

authors： Marcial MA,Hauser SC,Cibas ES,Braver J

更新日期：1986-08-01 00:00:00