Racial disparities in awareness and treatment of atrial fibrillation: the REasons for Geographic and Racial Differences in Stroke (REGARDS) study.

abstract：:We examined the 21-aminosteroid U74006F, a potent inhibitor of lipid peroxidation, for potential neuroprotective effects in a canine model of complete cerebral ischemia. Two 1.5-mg/kg boluses were administered to six dogs, the first bolus 15 minutes prior to a 12-minute episode of complete cerebral ischemia and the se...

journal_title：Stroke

authors： Perkins WJ,Milde LN,Milde JH,Michenfelder JD

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to assess the geographic proximity of patients with stroke in California to centers that performed specific threshold volumes of mechanical embolectomy procedures each year. METHODS:We identified all patients who were hospitalized for acute ischemic stroke at all nonfederal acute care ...

journal_title：Stroke

authors： Choi JC,Hsia RY,Kim AS

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Cerebral fat embolism syndrome is a rare, but potentially lethal, complication of long bone fractures. Neurological symptoms are variable, and the clinical diagnosis is difficult. The purpose of this case study is to demonstrate the value of diffusion-weighted MRI of the brain for early diagnosis of fat embo...

journal_title：Stroke

authors： Parizel PM,Demey HE,Veeckmans G,Verstreken F,Cras P,Jorens PG,De Schepper AM

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The present study determines associations between early blood pressure (BP) variability and stroke outcomes after intravenous thrombolysis. METHODS:In 527 stroke patients receiving intravenous alteplase (0.6 mg/kg), BP was measured 8 times within the first 25 hours. BP variability was determined...

journal_title：Stroke

authors： Endo K,Kario K,Koga M,Nakagawara J,Shiokawa Y,Yamagami H,Furui E,Kimura K,Hasegawa Y,Okada Y,Okuda S,Namekawa M,Miyagi T,Osaki M,Minematsu K,Toyoda K

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Carotid artery intima-media thickness (IMT) is a marker of cardiovascular disease associated with incident stroke. We studied whether IMT rate of change is associated with stroke. METHODS:We studied 5028 participants of the Multi-Ethnic Study of Atherosclerosis (MESA) comprising white, Chinese, ...

journal_title：Stroke

authors： Polak JF,Pencina MJ,O'Leary DH,D'Agostino RB

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The administration of glucose has been shown to worsen brain injury in adult animals but has no effect on the severity of injury in newborn rats. We wished to see whether the results in newborn rats could be extended to another newborn animal. METHODS:In 44 0- to 3-day-old piglets, hypoxic-ische...

journal_title：Stroke

authors： LeBlanc MH,Huang M,Vig V,Patel D,Smith EE

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Computed tomography (CT) is used to study coronary artery plaques, but little is known about its potential to characterize plaque composition. This study assesses the relation between carotid calcium score (CCS) by CT and plaque composition, namely extracellular matrix, inflammatory mediators, an...

journal_title：Stroke

authors： Edsfeldt A,Dias N,Elmståhl B,Müller MF,Berg K,Nitulescu M,Persson A,Ekberg O,Gonçalves I

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In animal models of cerebral ischemia, matrix metalloproteinase (MMP) expression was significantly increased and related to blood-brain barrier disruption, edema formation, and hemorrhagic transformation (HT). MMP inhibitors reduce HT after embolic ischemia in tissue-type plasminogen activator-tr...

journal_title：Stroke

authors： Montaner J,Alvarez-Sabín J,Molina CA,Anglés A,Abilleira S,Arenillas J,Monasterio J

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:To judge the efficacy of new, putative stroke therapies, we need a method to measure neurological deficit accurately in groups of patients before and after treatment. No single measurement technique has yet proven to be universally acceptable, but one approach is the use of rating instruments that summarize ...

journal_title：Stroke

authors： Lyden PD,Lau GT

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:This study aimed to identify aspects of the caregiving situation contributing to family caregivers' psychological well-being. METHODS:Longitudinal cohort study with structured quantitative interviews 1, 3, 6, and 12 months post stroke. A subset of participants also completed surveys 18 and 24 mo...

journal_title：Stroke

authors： Cameron JI,Stewart DE,Streiner DL,Coyte PC,Cheung AM

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Approximately one fourth of stroke occur during sleep. Despite the clinical and radiological similarities between wake-up stroke (WUS) and non-WUS, the functional outcomes of WUS are largely unknown. METHODS:This retrospective analysis reviewed 2289 consecutive patients with acute ischemic strok...

journal_title：Stroke

authors： Kim BJ,Lee SH,Shin CW,Ryu WS,Kim CK,Yoon BW

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Exogenously administered fructose-1,6-bisphosphate reduces neuronal injury from hypoxic or ischemic brain insults. To test the hypothesis that fructose-1,6-bisphosphate prevents changes in intracellular calcium ([Ca2+]i) and high-energy phosphate levels, we measured [Ca2+]i, intracellular pH (pHi...

journal_title：Stroke

authors： Bickler PE,Kelleher JA

更新日期：1992-11-01 00:00:00

abstract：:In children with Moyamoya disease, transient ischemic attacks often occur during hyperventilation, and the frequency of attacks usually decreases with advancing age. To elucidate the mechanism of the attacks, the regional cerebral blood flow was measured during rest and/or hyperventilation in children aged 3-16 with M...

journal_title：Stroke

authors： Tagawa T,Naritomi H,Mimaki T,Yabuuchi H,Sawada T

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In 6% to 9% of patients with subarachnoid hemorrhage (SAH), familial aggregation occurs; truly familial cases carry a worse prognosis than sporadic cases and raise the question of screening. If relatives have died from SAH, the family history is often the only available clue to the diagnosis, but...

journal_title：Stroke

authors： Bromberg JE,Rinkel GJ,Algra A,Greebe P,Beldman T,van Gijn J

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is no consensus on whether anticoagulation should be continued or temporarily stopped in patients suffering acute ischemic stroke while using anticoagulation. We assessed treatment variations and outcomes in these patients. METHODS:Post hoc analysis of PASS (Preventive Antibiotics in Strok...

journal_title：Stroke

authors： Groot AE,Vermeij JM,Westendorp WF,Nederkoorn PJ,van de Beek D,Coutinho JM

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intravenous thrombolysis (IVT) within 4.5 hours from symptom onset improves functional outcome in patients with acute ischemic stroke. Its use in patients with previous stroke within the preceding 3 months is contraindicated because of the assumed higher risk of intracranial hemorrhage. In additi...

journal_title：Stroke

authors： Kahles T,Mono ML,Heldner MR,Baumgartner RW,Sarikaya H,Luft A,Bohlhalter S,Traenka C,Engelter ST,Kurka N,Köhrmann M,Curtze S,Michel P,Tatlisumak T,Nedeltchev K

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We examined patient demographic and hospital characteristics and clinical predictors of delay time from hospital arrival until CT among 20 374 patients enrolled in the North Carolina Collaborative Stroke Registry (January 2005 to April 2008). METHODS:Delay time was log-transformed in linear regr...

journal_title：Stroke

authors： Rose KM,Rosamond WD,Huston SL,Murphy CV,Tegeler CH

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study was to determine the 30-day mortality and morbidity of intracerebral hemorrhage in a large metropolitan population and to determine the most important predictors of 30-day outcome. METHODS:We reviewed the medical records and computed tomographic films for all cases of spont...

journal_title：Stroke

authors： Broderick JP,Brott TG,Duldner JE,Tomsick T,Huster G

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The prevalence of silent brain infarcts varies from 8% to 28% in the general elderly population. Silent brain infarcts are associated with increased risk of subsequent stroke and cognitive dysfunction. By definition, silent strokes lack clinically overt stroke-like symptoms and fail to come to cl...

journal_title：Stroke

authors： Saini M,Ikram K,Hilal S,Qiu A,Venketasubramanian N,Chen C

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purposes of this study were to assess the relationships between anatomic and technical factors and the 30-day risk of stroke or death after carotid angioplasty and stenting in the Endarterectomy versus Stenting in Patients with Symptomatic Severe Carotid Stenosis (EVA-3S) trial and to perform...

journal_title：Stroke

authors： Naggara O,Touzé E,Beyssen B,Trinquart L,Chatellier G,Meder JF,Mas JL,EVA-3S Investigators.

更新日期：2011-02-01 00:00:00

abstract：:To study the effects of antithrombotic therapy in experimental stroke, we have characterized a baboon model of acute cerebrovascular thrombosis. In this model an inflatable silastic balloon cuff has been implanted by transorbital approach around the right middle cerebral artery (MCA), proximal to the take-off of the l...

journal_title：Stroke

authors： Del Zoppo GJ,Copeland BR,Harker LA,Waltz TA,Zyroff J,Hanson SR,Battenberg E

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Subarachnoid hemorrhage (SAH) caused by ruptured intracranial aneurysm affects approximately 16 000 Americans annually, and almost 40% of affected patients die within 30 days despite the best current therapy. Prevention of SAH is therefore of paramount importance. We present a preliminary analysi...

journal_title：Stroke

authors： Kissela BM,Sauerbeck L,Woo D,Khoury J,Carrozzella J,Pancioli A,Jauch E,Moomaw CJ,Shukla R,Gebel J,Fontaine R,Broderick J

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The modified Rankin Scale (mRS) is widely used to assess global outcome after stroke. The aim of the study was to examine rater variability in assessing functional outcomes using the conventional mRS, and to investigate whether use of a structured interview (mRS-SI) reduced this variability. MET...

journal_title：Stroke

authors： Wilson JT,Hareendran A,Hendry A,Potter J,Bone I,Muir KW

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We studied whether the inducible nitric oxide synthase (iNOS) inhibitor aminoguanidine reduces focal cerebral ischemic damage in a relatively noninvasive stroke model in which the rat middle cerebral artery (MCA) is occluded using an intravascular filament. METHODS:In rats anesthetized with halo...

journal_title：Stroke

authors： Zhang F,Casey RM,Ross ME,Iadecola C

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Poststroke cognitive decline and white matter lesions (WML) are related to poor poststroke survival. Whether cognitive reserve as reflected by educational history associates with cognitive decline, recurrent strokes, and poststroke mortality independent of WML is not known. METHODS:A total of 48...

journal_title：Stroke

authors： Ojala-Oksala J,Jokinen H,Kopsi V,Lehtonen K,Luukkonen L,Paukkunen A,Seeck L,Melkas S,Pohjasvaara T,Karhunen P,Hietanen M,Erkinjuntti T,Oksala N

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Anticoagulation is a highly effective secondary prevention in patients with cardioembolic stroke and atrial fibrillation/flutter (AF). However, the condition remains underdiagnosed, because paroxysmal AF may be missed by diagnostic tests in the acute phase. In this study, the sensitivity of AF de...

journal_title：Stroke

authors： Kallmünzer B,Breuer L,Hering C,Raaz-Schrauder D,Kollmar R,Huttner HB,Schwab S,Köhrmann M

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Transcranial Doppler (TCD) monitoring of mean blood flow velocity (mV) during head-upright tilt can allow testing of cerebral autoregulation. Nonetheless, head-upright tilt can induce changes in the ventilation-perfusion relationship and/or respiratory activity that might influence TCD data. MET...

journal_title：Stroke

authors： Cencetti S,Bandinelli G,Lagi A

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study is to report on the use of transcranial Doppler ultrasonography as a noninvasive diagnostic monitoring tool during local intra-arterial thrombolysis in a patient with acute embolic occlusion of the middle cerebral artery. CASE DESCRIPTION:We describe a 41-year-old woman wit...

journal_title：Stroke

authors： Karnik R,Stelzer P,Slany J

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Quantitative data on sensory impairment in stroke patients are limited. We measured the perception thresholds for temperature and thermal pain in patients with different lacunar syndromes, correlated the results with clinical and magnetic resonance imaging (MRI) findings, and studied the long-ter...

journal_title：Stroke

authors： Samuelsson M,Samuelsson L,Lindell D

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We examined the relationship of carotid artery lesions (CALs), with and without acoustic shadowing (AS), to incident ischemic stroke events in the Atherosclerosis Risk in Communities study cohort. METHODS:The study population consisted of 13 123 men and women aged 45 to 64 years, and free of str...

journal_title：Stroke

authors： Hunt KJ,Evans GW,Folsom AR,Sharrett AR,Chambless LE,Tegeler CH,Heiss G

更新日期：2001-05-01 00:00:00