Abstract:
PURPOSE:Enhancing Standard Cardiac Rehabilitation with Stress Management Training in Patients with Heart Disease (ENHANCED) is a randomized clinical trial funded by the National Heart Lung and Blood Institute to evaluate the effects of stress management training (SMT) on changes in biomarkers of risk and quality of life for patients enrolled in traditional exercise-based cardiac rehabilitation (CR). METHODS:One hundred fifty cardiac patients recruited from Duke University and the University of North Carolina will be evaluated and randomized to CR enhanced by SMT (including sessions devoted to relaxation training, cognitive restructuring, communication skills, and problem solving) or to standard exercise-based CR. Before and after 12 weeks of treatment, patients will undergo a battery of psychometric questionnaires and evaluation of cardiovascular biomarkers, including measures of flow-mediated dilation, heart rate variability, baroreflex sensitivity, platelet function and inflammation, and ischemia during laboratory mental stress testing. The primary outcomes include a composite measure of stress (distress, depression, anxiety, and hostility and 24-hour urinary catecholamines and cortisol) and a composite measure of cardiac biomarkers of risk (vascular endothelial function, cardiac vagal control, inflammation, platelet function, and mental stress-induced myocardial ischemia). Secondary outcomes include measures of quality of life as well as clinical events, including death, hospitalizations, myocardial infarction, and revascularization procedures. RESULTS:This article reviews prior studies in the area and describes the design of the ENHANCED study. Several key methodological issues are discussed including the assessment of biomarkers of risk and barriers to the integration of SMT into traditional CR. CONCLUSIONS:The ENHANCED study will provide important information by determining to what extent SMT combined with exercise-based CR may improve prognosis and quality of life in vulnerable cardiac patients.
journal_name
J Cardiopulm Rehabil Prevjournal_title
Journal of cardiopulmonary rehabilitation and preventionauthors
Blumenthal JA,Wang JT,Babyak M,Watkins L,Kraus W,Miller P,Hinderliter A,Sherwood Adoi
10.1097/HCR.0b013e3181d0c1d3subject
Has Abstractpub_date
2010-03-01 00:00:00pages
77-84issue
2eissn
1932-7501issn
1932-751Xpii
01273116-201003000-00002journal_volume
30pub_type
杂志文章,随机对照试验abstract:PURPOSE:Obstructive sleep apnea (OSA) is prevalent in patients with cardiovascular disease and is often undiagnosed. The purpose of this study was to determine the utility of communicating OSA risk with the patients in a diabetes and cardiac rehabilitation program (CRP) and primary care physicians. METHODS:Following a...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章
doi:10.1097/HCR.0000000000000186
更新日期:2016-11-01 00:00:00
abstract:PURPOSE:Cardiac rehabilitation (CR) has been shown to reduce cardiac risk and improve the psychosocial functioning of participants. This study examines gender differences on several psychosocial indicators across the course of CR. METHODS:Patients (N = 380; 67.9% men and 32.1% women) referred from local inpatient and ...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章
doi:10.1097/HCR.0000000000000034
更新日期:2014-01-01 00:00:00
abstract:PURPOSE:Cardiorespiratory fitness is positively related to heart failure (HF) prognosis, but lack of time and low energy are barriers for adherence to exercise. We, therefore, compared the effect of low-volume time-based resistance exercise training (TRE) with aerobic moderate-intensity cycling (AMC) on maximal and sub...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章,随机对照试验
doi:10.1097/HCR.0000000000000304
更新日期:2018-05-01 00:00:00
abstract:PURPOSE:The purpose of this study was to examine emotional distress, alexithymia, and coping styles as predictors of cardiac rehabilitation (CR) outcomes and attendance. METHODS:Participants included 56 patients in an outpatient CR program (65% male, 59% white, M = 61.1 years) who completed self-report measures of emo...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章
doi:10.1097/HCR.0b013e318276864c
更新日期:2013-01-01 00:00:00
abstract:PURPOSE:We investigated whether cardiac rehabilitation participation increases circulating endothelial progenitor cells (EPCs) and benefits vasculature in patients already on stable therapy previously shown to augment EPCs and improve endothelial function. METHODS:Forty-six of 50 patients with coronary artery disease ...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 临床试验,杂志文章
doi:10.1097/01.HCR.0000265031.10145.50
更新日期:2007-03-01 00:00:00
abstract:PURPOSE:Although cardiac rehabilitation programs have been shown to decrease cardiovascular risk, morbidity, and mortality, few programs have integrated a balanced mind/body approach in which patients are taught the relaxation response and utilize cognitive behavior skills for stress management, along with diet and exe...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章
doi:10.1097/HCR.0b013e3181a33352
更新日期:2009-07-01 00:00:00
abstract:PURPOSE:The purposes of this systematic review were to (1) review the literature related to the demographic and biopsychosocial-spiritual factors impacting cardiac rehabilitation (CR) referral and participation of African American patients with cardiovascular disease (CVD); (2) identify barriers and facilitators to CR ...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章,评审
doi:10.1097/HCR.0000000000000183
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:Despite well-documented positive benefits, cardiac rehabilitation (CR) is an underutilized resource for patients following a cardiac event or intervention. Bias in the CR referral process has led to programs designed to ensure that all eligible patients receive a referral. The purpose of the current investigati...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章
doi:10.1097/HCR.0b013e31827e14da
更新日期:2013-05-01 00:00:00
abstract:PURPOSE:The application of active video games (AVGs) during cardiac rehabilitation (CR) sessions could potentially facilitate patient adherence. The feasibility, safety, and efficacy of in-class AVG supplementation as an alternative to conventional phase 2 programs were investigated. METHODS:A pilot, evaluator-blinded...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章,随机对照试验
doi:10.1097/HCR.0000000000000224
更新日期:2017-07-01 00:00:00
abstract:PURPOSE:Pulmonary rehabilitation (PR) is effective in patients with moderate to severe chronic obstructive pulmonary disease (COPD). However, the effects of PR in patients with mild COPD have not yet been established. Thus, this study investigated the short- and long-term effects of PR in patients with mild COPD in com...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章
doi:10.1097/HCR.0000000000000219
更新日期:2016-11-01 00:00:00
abstract:PURPOSE:We evaluated the effectiveness of a computerized cardiac rehabilitation (CR) recruiting strategy instituted during the hospital discharge process after acute myocardial infarction (MI) or coronary artery bypass graft (CABG) surgery. The computerized referral was designed to enhance an already-established nurse-...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章
doi:10.1097/HCR.0b013e3181b4ca75
更新日期:2009-11-01 00:00:00
abstract:PURPOSE:To evaluate the response of patients with obesity to a cardiac rehabilitation program (CRP), compared with patients without obesity. METHODS:We performed a retrospective analysis of 731 patients who completed phase II of a CRP after an acute coronary syndrome. The response to the CRP was assessed using the rel...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章
doi:10.1097/HCR.0000000000000442
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:Inflammatory and vascular markers have proved to be predictors of outcome in myocardial infarction and heart failure. We evaluated several circulating markers of cardiac stress, inflammation, and endothelial function to investigate their ability to predict short-term functional recovery and long-term clinica...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章,多中心研究
doi:10.1097/HCR.0b013e31823be0f4
更新日期:2012-01-01 00:00:00
abstract:PURPOSE:Outpatient cardiac rehabilitation (CR) participation after myocardial infarction (MI) reduces all-cause mortality; however, less is known about effects of CR on post-MI hospitalization. The study objective was to investigate effects of CR on hospitalization following acute MI among older adults. METHODS:Medica...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章
doi:10.1097/HCR.0000000000000452
更新日期:2020-03-01 00:00:00
abstract:PURPOSE:Exercise training is established for the treatment of peripheral artery disease; however the additional benefit of pharmacologic therapy with exercise has not been studied. This trial tested the hypothesis that propionyl-L-carnitine (PLC), in combination with monitored home-based exercise training, would improv...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/HCR.0b013e3181f1fd65
更新日期:2011-03-01 00:00:00
abstract:PURPOSE:To determine whether individuals with chronic obstructive pulmonary disease (COPD) have decreased arm activity during daily life compared with healthy controls and explore the relationships between arm activity during daily life and arm functional measures in individuals with COPD. METHODS:This was a prospecti...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章
doi:10.1097/HCR.0000000000000153
更新日期:2016-03-01 00:00:00
abstract:PURPOSE:The objective of this study was to use a modified Philadelphia Panel rating method to evaluate the evidence supporting the use of therapeutic exercise interventions in patients with congestive heart failure (CHF). METHODS:A computerized literature search was conducted. Inclusion criteria included studies using...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章,评审
doi:10.1097/01.HCR.0000300263.07764.4a
更新日期:2007-11-01 00:00:00
abstract::Outcome measurement in cardiopulmonary rehabilitation is required for optimal assessment of program quality, effectiveness of treatments, and evaluation of patient progress. Recent position statements from the American Association of Cardiovascular and Pulmonary Rehabilitation (AACVPR), American College of Cardiology,...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章,评审
doi:10.1097/HCR.0b013e3181927843
更新日期:2009-05-01 00:00:00
abstract:PURPOSE:Type 2 diabetes (T2D) is associated with subclinical abnormalities in left ventricular function and an increased downstream risk for heart failure. Exercise training has been associated with significant improvement in cardiorespiratory fitness among these patients. However, its impact on cardiac function is not...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章,meta分析
doi:10.1097/HCR.0000000000000353
更新日期:2018-11-01 00:00:00
abstract:PURPOSE:Cardiac rehabilitation (CR) programs decrease morbidity and mortality rates in patients with coronary artery disease, the leading cause of death in Latin America. This study was carried out to assess the characteristics and current level of CR program implementation in South America. METHODS:We carried out a s...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章,多中心研究
doi:10.1097/HCR.0b013e318272153e
更新日期:2013-01-01 00:00:00
abstract:PURPOSE:Psychoeducation is a recommended component of cardiac rehabilitation, but to date, evidence from high quality trials examining behavior change has not been synthesized. The primary aim of this systematic review was to examine the effectiveness of psychoeducation on behavior change in adults with coronary artery...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章,meta分析,评审
doi:10.1097/HCR.0b013e318220a7c9
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:Heart failure with reduced ejection fraction (HFrEF) and chronic obstructive pulmonary disease (COPD) are relatively common conditions with similar symptoms of exercise intolerance and dyspnea. The aim of this study was to compare exercise capacity, ventilatory response, and breathing pattern in patient grou...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章
doi:10.1097/HCR.0000000000000528
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Hospitalization with acute exacerbation of chronic obstructive pulmonary disease (COPD) is common and costly to the health care system. Pulmonary rehabilitation (PR) can improve symptom burden and morbidity associated with COPD. The use of PR among Medicare beneficiaries is poor, and the use by Veterans Heal...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章
doi:10.1097/HCR.0000000000000357
更新日期:2018-11-01 00:00:00
abstract:PURPOSE:To determine the utility of equations that use the 6-minute walk test (6MWT) results to estimate peak oxygen uptake ((Equation is included in full-text article.)o2) and peak work rate with chronic obstructive pulmonary disease (COPD) patients in a clinical setting. METHODS:This study included a systematic revi...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章,评审
doi:10.1097/HCR.0000000000000129
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:The Incremental Shuttle Walking Test (ISWT) is used to assess exercise capacity in chronic obstructive pulmonary disease (COPD) and is employed as an outcome measure for pulmonary rehabilitation. We studied the value of this test in predicting survival in COPD patients enrolled in a rehabilitation program. ...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章
doi:10.1097/HCR.0b013e3181e1736b
更新日期:2010-11-01 00:00:00
abstract:PURPOSE:The efficacy of alternative delivery models for a cardiac rehabilitation program (CRP) in low- and middle-income countries is not well documented. This study compared the traditional hospital-based CRP with a hybrid CRP in western Iran. METHODS:This observational study was conducted with postcoronary surgery p...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章
doi:10.1097/HCR.0000000000000087
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:To compare exercise training intensity during standard cardiac rehabilitation (S-CR) versus hybrid-CR (combined clinic- and remote home-/community-based). METHODS:The iATTEND (improving ATTENDance to cardiac rehabilitation) trial is currently enrolling subjects and randomizing patients to S-CR versus hybrid-CR...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章
doi:10.1097/HCR.0000000000000569
更新日期:2021-01-01 00:00:00
abstract:PURPOSE:To examine whether the effects of psychosocial and vocational interventions delivered in the first 3 mo post-acute myocardial infarction (AMI) are effective for improving work outcomes compared with other interventions. METHODS:A search was completed for English language publications up to March 2016 across 4 ...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章
doi:10.1097/HCR.0000000000000261
更新日期:2018-07-01 00:00:00
abstract:PURPOSE:Coronary artery bypass graft (CABG) surgery patients participating in cardiac rehabilitation (CR) experience improvements in aerobic fitness, but there has been little study of outcomes for heart valve (HV) surgical patients. The primary aims of this study were to evaluate baseline peak aerobic capacity for HV ...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章
doi:10.1097/HCR.0000000000000104
更新日期:2015-07-01 00:00:00
abstract:PURPOSE:Body mass index (BMI) has prognostic value in patients with chronic lung disease. Pulmonary rehabilitation improves quality of life. This study investigated whether BMI predicts change in disease-specific quality of life following pulmonary rehabilitation. METHODS:Subjects (N = 61), who completed pulmonary reh...
journal_title:Journal of cardiopulmonary rehabilitation and prevention
pub_type: 杂志文章
doi:10.1097/HCR.0b013e3181e17607
更新日期:2010-09-01 00:00:00