Controlled application and removal of liposomal therapeutics: effective elimination of pegylated liposomal doxorubicin by double-filtration plasmapheresis in vitro.

abstract：BACKGROUND:Autologous stem cell transplantation (auto-SCT) is a treatment approach in non-Hodgkin lymphoma (NHL) patients. The options for mobilization of CD34+ cells to support high-dose therapy are granulocyte-colony stimulating factors (G-CSFs) alone or after chemotherapy. Limited data exist on the efficacy of lipeg...

journal_title：Journal of clinical apheresis

authors： Partanen A,Turunen A,Valtola J,Vasala K,Ågren L,Penttilä K,Pyörälä M,Kuittinen T,Mäntymaa P,Pelkonen J,Jantunen E,Varmavuo V

更新日期：2020-08-01 00:00:00

abstract：:This study was undertaken to evaluate the relationship between the time to recovery of peripheral blood counts and CD34+ cells in the peripheral blood (PB) and apheresis collections of patients undergoing intensive chemotherapy followed by rhG-CSF. Twenty-three patients with a median age of 42 years (range 17-64) with...

journal_title：Journal of clinical apheresis

authors： Williams O,Demirer T,Lilleby K,Buckner CD,Bensinger WI

更新日期：1998-01-01 00:00:00

abstract：:Extracorporeal photopheresis (ECP) in young pediatric patients has a risk for procedural hypotension and anemia due to extracorporeal fluid shifts. A standard mitigation policy in these patients is to prime the device with packed red blood cells (RBC) or whole blood. We now report multiple episodes of hemolysis while ...

journal_title：Journal of clinical apheresis

authors： Cooling L,Thompson T,Downs T,Abusin G,Yanik G

更新日期：2019-12-01 00:00:00

abstract：:Complement-derived anaphylatoxin may be one of the causes of vascular injury and an indicator of activity in systemic lupus erythematosus (SLE). The present study examines the effectiveness of dextran sulfate (DS) column immunoadsorption treatment to remove anaphylatoxins (C3a, C4a, and C5a) from the blood of patients...

journal_title：Journal of clinical apheresis

authors： Matsuki Y,Suzuki K,Kawakami M,Ishizuka T,Hidaka T,Nakamura H

更新日期：1998-01-01 00:00:00

abstract：:Dysmetabolic iron overload syndrome is a rare event causing hepatic impairment with serious long-term side effects. Here, we describe a case of metabolic syndrome-related hepatic iron overload that showed a rapid, effective, and safe response to erythrocytapheresis. J. Clin. Apheresis 31:443-447, 2016. © 2015 Wiley Pe...

journal_title：Journal of clinical apheresis

authors： Vetro C,Rosso R,Palmucci S,Russello M,Colletta G,Romeo MA,Ximenes B,Romano A,Palumbo GA,Di Raimondo F

更新日期：2016-10-01 00:00:00

abstract：:The practice of transfusing ABO-incompatible platelets, driven primarily by concerns about inventory management, has been considered generally safe because the accompanying plasma is usually diluted in the recipient's total blood volume. However, if the platelet product contains a large volume of plasma or a high conc...

journal_title：Journal of clinical apheresis

authors： Sapatnekar S,Sharma G,Downes KA,Wiersma S,McGrath C,Yomtovían R

更新日期：2005-12-01 00:00:00

abstract：:We present clinical data on two boys with chronic relapsing polyneuropathy. Their recurrent episodes of weakness had produced marked disability which was unresponsive to continuous prednisone therapy. Plasmapheresis produced dramatic improvement in muscle strength and functional ability. The remissions induced have be...

journal_title：Journal of clinical apheresis

authors： Connor RK,Ziter FA,Anstall HB

更新日期：1982-01-01 00:00:00

abstract：:The infusion of high-dose (275 mg/kg body weight) immune globulin intravenous (IGIV) after 466 plasma exchanges in 64 patients with autoimmune disease was studied. Side effects occurred during 15% of IGIV infusions. For the most part they were transient and mild, and could be controlled by slowing the infusion rate. T...

journal_title：Journal of clinical apheresis

authors： Dau PC

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Currently, low titer A plasma is used on a routine basis in bleeding trauma patients of unknown AB type. Three AB non-bleeding apheresis patients are presented here who safely received a combination of AB and low titer A plasma during therapeutic plasma exchange (TPE). One control AB patient received AB plas...

journal_title：Journal of clinical apheresis

authors： Kaplan A,Sevcik J,Kiss JE

更新日期：2019-02-01 00:00:00

abstract：:This study examined the incidence and predictors of peripheral blood stem cell (PBSC) mobilization failure in patients with multiple myeloma (MM). Retrospective data for 104 patients who received granulocyte colony-stimulating factor (G-CSF) alone or with cyclophosphamide as mobilization regimens were analyzed. The ra...

journal_title：Journal of clinical apheresis

authors： Jung SH,Yang DH,Ahn JS,Kim YK,Kim HJ,Lee JJ

更新日期：2014-12-01 00:00:00

abstract：:Leukemic-dendritic cells (leukemic-DCs) have certain limitations, which include difficult generation in 30-40% of patients, and low levels of expression of several key molecules. Therefore, an alternative approach using monocyte-derived DCs pulsed with tumor antigens is required. We investigated the possibility of imm...

journal_title：Journal of clinical apheresis

authors： Lee JJ,Park MS,Park JS,Kang HK,Kim SK,Nguyen Pham TN,Zhu XW,Cho D,Nam JH,Kim YJ,Rhee JH,Chung IJ,Kim HJ

更新日期：2006-10-01 00:00:00

abstract：:Two patients suffering from allergic bronchial asthma who showed no improvement despite six and four weeks, respectively, of drug therapy were successfully treated with therapeutic plasma exchange. The first patient had no attacks over a period of five months, and the other patient had none for over one year. Although...

journal_title：Journal of clinical apheresis

authors： Bambauer R,Jutzler GA,Micka K,Austgen M,Schlimmer P,Trendelenburg F

更新日期：1984-01-01 00:00:00

abstract：:Blood group incompatibility remains a significant barrier to kidney transplantation. Approximately, one-third of donors are blood group incompatible with their intended recipient. Options for these donor-recipient pairs include blood group incompatible transplantation or kidney paired donation. However, the optimal pr...

journal_title：Journal of clinical apheresis

authors： Yabu JM,Fontaine MJ

更新日期：2015-12-01 00:00:00

abstract：:Acute thrombotic thrombocytopenic purpura (TTP) occurred in three patients following abdominal surgeries. One patient underwent extensive lysis for intestinal adhesions with bowel resection, another cholecystectomy for acute cholecystitis, and the third right colectomy and partial intestinal resection for colon cancer...

journal_title：Journal of clinical apheresis

authors： Chang JC,El-Tarabily M,Gupta S

更新日期：2000-01-01 00:00:00

abstract：:Recently very potent extracorporeal cholesterol-lowering treatment options have become available for patients with hypercholesterolemia. LDL immunoapheresis treatment selectively removes LDL and lipoprotein(a) from the circulation. Since LDL is the major carrier of lipophilic antioxidants in plasma, the purpose of the...

journal_title：Journal of clinical apheresis

authors： Cauza E,Jansen M,Resch U,Dunky A,Derfler K,Winklhofer-Roob BM,Kostner K

更新日期：2004-01-01 00:00:00

abstract：:Because the administration of hematopoietic growth factors and the use of stem cell support often fails to alleviate the neutropenic phase induced by cytotoxic drugs, several investigators have attempted to expand ex vivo hematopoietic progenitors for clinical use. These attempts have clearly shown that the cultured c...

journal_title：Journal of clinical apheresis

authors： Estrov Z,Huh YO,Ginsberg CF,Harris D,Van Q,Mirza NQ,Talpaz M,Korbling M

更新日期：2002-01-01 00:00:00

abstract：:Targeted extracorporeal granulocyte and monocyte apheresis (GMA) has produced clinical efficacy together with down modulation of specific inflammatory cytokines in patients with ulcerative colitis (UC). This study was to investigate if preoperative GMA produces immunological effect on dysregulated immune activity afte...

journal_title：Journal of clinical apheresis

authors： Bamba T,Yamamoto T,Umegae S,Matsumoto K

更新日期：2014-04-01 00:00:00

abstract：:We sought to optimize direct intravenous infusion of calcium gluconate (CaGlu) for maintaining plasma ionized calcium concentration ([Ca2+ ]) and preventing hypocalcemic reactions during 34 consecutive 1-volume therapeutic plasma exchanges (TPEs) in eight patients. CaGlu, 2 g in 50 mL of 0.9% NaCl, was prepared by our...

journal_title：Journal of clinical apheresis

authors： Zhao Y,Garrity D,Graves M,Linden J,St Pierre P,Ducharme P,Greene M,Vauthrin M,Weinstein R

更新日期：2019-12-01 00:00:00

abstract：:Folinic acid (FA) has been reported to expand the pool of peripheral blood stem cells (PBSC) after chemotherapy. We evaluated the efficacy of FA for harvesting PBSC following cytotoxic chemotherapy in 4 patients with acute leukemia. After achieving a complete remission (CR), 3 courses of chemotherapy for a consolidati...

journal_title：Journal of clinical apheresis

authors： Teshima T,Harada M,Takamatsu Y,Inaba S,Kondo S,Akashi K,Okamura T,Niho Y

更新日期：1992-01-01 00:00:00

abstract：:The influence of 6 weeks of cyclosporin A (CYA), followed by a further 6 weeks of this agent in combination with plasma exchange (PE), was defined on panel reactivity and titre of preformed cytotoxic antibodies in stable patients on haemodialysis awaiting renal transplantation. Nine individuals with antibodies to 30% ...

journal_title：Journal of clinical apheresis

authors： Swanepoel CR,Cassidy MJ,May M,Oudshoorn M,du Toit E,Wood L,Jacobs P

更新日期：1991-01-01 00:00:00

abstract：:Current management of heparin-induced thrombocytopenia (HIT) involves prompt discontinuation of all heparin products and concomitant initiation of a direct thrombin or anti-Xa inhibitor for anticoagulation. In the setting of HIT complicated by an urgent need for cardiopulmonary bypass (CPB), the safety and the efficac...

journal_title：Journal of clinical apheresis

authors： Cho JH,Parilla M,Treml A,Wool GD

更新日期：2019-02-01 00:00:00

abstract：:Mobilized PBSC are the main source for allogeneic HSCT. We aimed to evaluate factors that affect CD34+ cell yield including the donor's age, gender, BSA, processed blood volume and the method of G-CSF dose calculation. Data from 170 healthy donors were analyzed. The concentration of CD34+ cells in the peripheral blood...

journal_title：Journal of clinical apheresis

authors： Machaczka M,Hägglund H,Staver E,Joks M,Hassan M,Wahlin BE,Axdorph Nygell U

更新日期：2017-12-01 00:00:00

abstract：:Mobilized stem cells in the peripheral blood (PB) must be efficiently harvested at the appropriate time before autologous PB stem cell (PBSC) transplantation. Enumeration of CD34+ cells in the PB before apheresis predicts the number of PBSCs that can be collected, but the cytometric techniques used are complex and exp...

journal_title：Journal of clinical apheresis

authors： Mitani N,Yujiri T,Tanaka Y,Tanaka M,Fujii Y,Hinoda Y,Tanizawa Y

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Specialized centers claim a need for blood component production independent from the general blood transfusion services. We performed a prospective change control analysis of the transfer of platelet (PLT) production for hematological patients at the University Hospital Basel from the Departme...

journal_title：Journal of clinical apheresis

authors： Sigle JP,Medinger M,Stern M,Infanti L,Heim D,Halter J,Gratwohl A,Buser A

更新日期：2012-01-01 00:00:00

abstract：:The cell separator MCS-3P is an apheresis system offering the flexibility to collect standardized red blood cells, plasma, and/or platelets from one donor. Two different programs were used for the red cell apheresis--RBCP (collection of one unit of red cells and two units of plasma) and RBCPS (one unit of red cells an...

journal_title：Journal of clinical apheresis

authors： Matthes G,Tofote U,Krause KP,Pawlow I,Kucera W,Lerche D

更新日期：1994-01-01 00:00:00

abstract：INTRODUCTION:Algorithms have been developed to predict the platelet yield after apheresis from the donor's data, as well as the effect on the blood cell count, to extract an acceptable platelet number without affecting the donor. However, the evaluation of these algorithms has not been widely reported. This study aimed...

journal_title：Journal of clinical apheresis

authors： Cienfuegos-Pecina E,Ayala-De la Cruz S,Leal-Nava ER,Pérez-Olvera JA,Llaca-Díaz JM,Avilés-Rodríguez LE,Pérez-Chávez F,Díaz-Chuc EA

更新日期：2020-10-05 00:00:00

abstract：:Apheresis procedures in small children are technically challenging and require special planning with attention to extracorporeal volume. Discontinuous procedures such as extracorporeal photopheresis (ECP) require additional consideration. Alternative methods to perform ECP have been utilized in small children that req...

journal_title：Journal of clinical apheresis

authors： Schneiderman J,Jacobsohn DA,Collins J,Thormann K,Kletzel M

更新日期：2010-01-01 00:00:00

abstract：:Antisynthetase syndrome (ASS) is a rare condition characterized by interstitial lung disease (ILD), inflammatory myositis, fever, Raynaud phenomenon, mechanic's hand, and inflammatory polyarthritis in the setting of antibodies to amino acyl-transfer RNA synthetases, with anti-Jo-1 antibody being the most common. Progn...

journal_title：Journal of clinical apheresis

authors： Omotoso BA,Ogden MI,Balogun RA

更新日期：2015-12-01 00:00:00

abstract：:An improved method for intermittent-flow erythrocytapheresis in patients with sickle cell disease is reported. The method, a modification of the standard red cell exchange procedure for the Haemonetics 30S unit, dilutes with physiologic saline the patient's blood as it flows from the draw line and before it reaches th...

journal_title：Journal of clinical apheresis

authors： Castro O,Finke-Castro H,Coats D

更新日期：1986-01-01 00:00:00

abstract：:Peripheral blood stem cells (PBSC) reinfusion appears to hasten hematologic reconstitution following myeloablative therapy. While procurement of PBSC adds apheresis procedures, rapid engraftment could decrease the demand for platelet transfusions. To determine the impact of PBSC collection on workload in our apheresis...

journal_title：Journal of clinical apheresis

authors： Ghalie R,McLeod B,Richman C,Valentino L,Manson S,Netols C,Kaizer H

更新日期：1992-01-01 00:00:00