MiR-221 affects proliferation and apoptosis of gastric cancer cells through targeting SOCS3.

abstract：OBJECTIVE:Pharmacological post-conditioning (PC) by intermittent but not continuous administration of exogenous bradykinin (BK) reduces ischemia/reperfusion (I/R) injury via the Reperfusion Injury Salvage Kinase (RISK) pathway activation. We evaluated whether intermittent administration with icatibant (HOE140), a BK2R ...

journal_title：European review for medical and pharmacological sciences

authors： Sgarra L,Coco C,Montagnani M,Potenza MA

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:This paper aims to investigate the interaction mechanism between pioglitazone/simvastatin and the CD40-CD40 ligand (CD40-CD40L) system and to determine their interaction effects on atherosclerosis in rabbits. MATERIALS AND METHODS:Forty rabbits were randomly divided into five groups of eight: normal control,...

journal_title：European review for medical and pharmacological sciences

authors： Xue L,Zhu XH,Yang XF,Bao XC,Gao XQ,Qiu YH,Wu Z,Ji XP,Li HW

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:To illustrate the role of interleukin 6 (IL-6) in the progression of non-small cell lung cancer (NSCLC) via activating STAT1. PATIENTS AND METHODS:The level of IL-6 mRNA in 48 paired NSCLC tissues and matched normal ones was determined by quantitative Real Time-Polymerase Chain Reaction (qRT-PCR). Kaplan-Mei...

journal_title：European review for medical and pharmacological sciences

authors： Chen T,Li J,Zhou MH,Xu LJ,Pan TC

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:Obesity has been associated with hypothyroidism and cardiac autonomic dysfunction. The present study aimed to investigate whether cardiac autonomic dysfunction in young obese males might be related to an underlying thyroid disturbance. PATIENTS AND METHODS:On the basis of body mass index (BMI), 40 participan...

journal_title：European review for medical and pharmacological sciences

authors： Al-Trad BA,Faris MA,Al-Smadi M,Bashir A,Mansi M,Alaraj M,Al-Hazimi A

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:p38 mitogen-activated protein kinase (p38MAPK) is a critical negative regulator for nucleus pulposus (NP) cell metabolism contributing to intervertebral disc degeneration (IDD). Histone deacetylase 4 (HDAC4) has the ability to mediate cell proliferation and is affected by p38MAPK. It is unclear whether the p3...

journal_title：European review for medical and pharmacological sciences

authors： Wu YD,Guo ZG,Deng WJ,Wang JG

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:This study aims to detect the expression pattern of microRNA-375 in colorectal cancer (CRC), and to examine its specific mechanism in regulating the progression of CRC. PATIENTS AND METHODS:We detected microRNA-375 expression in 50 pairs of CRC and paracancerous tissues by quantitative real-time polymerase c...

journal_title：European review for medical and pharmacological sciences

authors： Wei LJ,Bai DM,Wang ZY,Liu BC

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to explore the expression of microRNA-106a in breast cancer (BC) and to further investigate its role in BC development and the potential regulatory mechanism. PATIENTS AND METHODS:72 pairs of BC tissues and para-cancerous tissues were collected, and microRNA-106a expression was dete...

journal_title：European review for medical and pharmacological sciences

authors： Liu C,Song YH,Mao Y,Wang HB,Nie G

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:Wilms tumor gene 1 (WT1) has been identified as an independent risk prognostic factor in acute leukemia. However, there exists a controversy that WT1 as a marker for minimal residual disease (MRD) monitoring in acute leukemias. We detected WT1-RNA transcript level to estimate the diagnostic value of monitorin...

journal_title：European review for medical and pharmacological sciences

authors： Zhang R,Yang JY,Sun HQ,Jia H,Liao J,Shi YJ,Li G

更新日期：2015-01-01 00:00:00

abstract：:Antifungal agents have greatly contributed to the improvement of public health. Nevertheless, antifungal resistant pathogens have increased during the past decade, becoming a serious concern. Candida albicans has been the most extensively studied pathogen in antifungal resistance because of their morbidity and mortali...

journal_title：European review for medical and pharmacological sciences

authors： Casalinuovo IA,Di Francesco P,Garaci E

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the influence of long non-coding ribonucleic acid (lncRNA) antisense non-coding RNA in the INK4 locus (ANRIL) on neuronal apoptosis in rats with cerebral infarction (CI), and to further explore the underlying mechanism of lncRNA ANRIL in the occurrence and development of ...

journal_title：European review for medical and pharmacological sciences

authors： Zhao JH,Wang B,Wang XH,Wang JR,Xu CW

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:We investigated the expression of annexin A5 (ANXA5) in human cholangiocarcinoma (CCA) cell line and its effect on proliferation, migration, and apoptosis of human CCA cells. MATERIALS AND METHODS:Expression of ANXA5 was detected by fluorescent quantitative reverse transcriptase polymerase chain reaction (qR...

journal_title：European review for medical and pharmacological sciences

authors： Ding XM,Li JX,Wang K,Wu ZS,Yao AH,Jiao CY,Qian JJ,Bai DS,Li XC

更新日期：2017-04-01 00:00:00

abstract：:The article "MiR-101 promotes nasopharyngeal carcinoma cell apoptosis through inhibiting Ras/Raf/MEK/ERK signaling pathway, by R.-S. Wu, E.-H. Qiu, J.-J. Zhu, J.-R. Wang, H.-L. Lin, published in Eur Rev Med Pharmacol Sci 2018; 22(1): 150-157-DOI: 10.26355/eurrev_201801_14112-PMID: 29364482" has been withdrawn from the...

journal_title：European review for medical and pharmacological sciences

authors： Wu RS,Qiu EH,Zhu JJ,Wang JR,Lin HL

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:To summarize the latest information on the relationship between genes and common forms of obesity, and to review genetic markers (SNPs and miRNA) that play a role in predisposing to common forms of obesity and related disorders. MATERIALS AND METHODS:We searched PubMed with the following keywords: (obesity[T...

journal_title：European review for medical and pharmacological sciences

authors： Vettori A,Pompucci G,Paolini B,Del Ciondolo I,Bressan S,Dundar M,Kenanoğlu S,Unfer V,Bertelli M,Geneob Project.

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to observe the association between N-myc downstream regulated gene 2 (NDRG2)/interleukin-6 (IL-6)/signal transducer and activator of transcription 3 (STAT3) signaling pathway and diabetic retinopathy (DR) in rats. MATERIALS AND METHODS:The model of diabetes was successfully establis...

journal_title：European review for medical and pharmacological sciences

authors： Wang Y,Zhai WL,Yang YW

更新日期：2020-04-01 00:00:00

abstract：CASE PRESENTATION:Diffuse large B-cell lymphoma (DLBCL) is the most common lymphoid malignancy and the most common type of non-Hodgkin's lymphomas, the stomach is the most common extranodal site. Gastric DLBCL is often characterized by epigastric pain and vomiting. We report a case of a 78-year-old female patient with ...

journal_title：European review for medical and pharmacological sciences

authors： Zhao KX,Dai GZ,Zhu JF

更新日期：2016-05-01 00:00:00

abstract：:Kaposi's sarcoma (KS) is a multicentric angioproliferative cancer of endothelial origin typically occurring in the context of immunodeficiency, i.e. coinfection with Human Immonodeficiency Virus (HIV) or transplantation. The incidence of KS has dramatically decreased in both US and Europe in the Highly Active Antiretr...

journal_title：European review for medical and pharmacological sciences

authors： La Ferla L,Pinzone MR,Nunnari G,Martellotta F,Lleshi A,Tirelli U,De Paoli P,Berretta M,Cacopardo B

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:Ventilator-induced lung injury (VILI) remains a challenge. This study was designed to investigate the effects of ambroxol on VILI and the underlying mechanisms in a rodent model. MATERIALS AND METHODS:Male Wistar rats weighing 310-380 g were divided into four groups (n=8 per group): 1) saline only, 2) ventil...

journal_title：European review for medical and pharmacological sciences

authors： Cao DW,Hou MX,Zhang XR

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:To explore the role of Id1 in ovarian cancer cell proliferation, invasion and apoptosis. MATERIALS AND METHODS:Lentivirus-based shRNA vectors were constructed to knockdown Id1 expression in SKOV3 ovarian cancer cells. The proliferation, invasion ability and apoptosis of SKOV3 cells were evaluated by CCK-8 as...

journal_title：European review for medical and pharmacological sciences

authors： Sun WZ,Li MH,Chu M,Wei LL,Bi MY,He Y,Yu LB

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:The purpose of this study is to examine the feasibility and prospective success associated with implementing and evaluating a six-week live music intervention on an inpatient neurorehabilitation ward. PATIENTS AND METHODS:In total 26 patients were included in this study. Out of which, 15 were patients and 11...

journal_title：European review for medical and pharmacological sciences

authors： Zhang CC,Mou L,Wang X,Guo D

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:Previous studies have found that IPO5 is a cancer-promoting gene. However, the role of IPO5 in esophageal cancer has not been reported. This study aims to investigate the expression characteristics of IPO5 in esophageal cancer, and to further analyze its relationship with clinical parameters and prognosis of ...

journal_title：European review for medical and pharmacological sciences

authors： Li XF,Aierken AL,Shen L

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:Neoplastic disease is frequently associated with poor nutritional status or severe malnutrition. Diet and nutritional intervention are becoming increasingly important for prognosis and quality of life in cancer patients. Accessible and repeatable tools for assessing nutritional status with body composition te...

journal_title：European review for medical and pharmacological sciences

authors： Di Renzo L,Marchetti M,Cioccoloni G,Gratteri S,Capria G,Romano L,Soldati L,Mele MC,Merra G,Cintoni M,De Lorenzo A

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:To analyze the clinical values of three commonly used scoring systems including Wells score, revised Geneva score and Pisa score in predicting pulmonary thromboembolism (PTE) in Xining area. PATIENTS AND METHODS:A total of 67 patients who had received CT pulmonary angiography (CTPA) in Qinghai Provincial Peo...

journal_title：European review for medical and pharmacological sciences

authors： Gu YH,Zhao Z

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the impact of a new formulation of probiotic mouthwash (PM), using Biocult strong® dissolved in neutral mouthwash. PATIENTS AND METHODS:Forty-two patients with cardiovascular disease (CVD) or type 1 and type 2 diabetes were enrolled. Plaque Control Record (PCR) and Bleeding on Probing (BOP) were ...

journal_title：European review for medical and pharmacological sciences

authors： Bollero P,Di Renzo L,Franco R,Rampello T,Pujia A,Merra G,De Lorenzo A,Docimo R

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:To identify the potential role of miR-490-3p in the development of esophageal squamous cell carcinoma (ESCC), and to explore the possible underlying mechanism. PATIENTS AND METHODS:Human ESCC tissues and cancer-adjacent normal tissues were collected. The mRNA expression level of miR-490-3p was detected by qu...

journal_title：European review for medical and pharmacological sciences

authors： Kang NN,Ge SL,Zhang RQ,Huang YL,Liu SD,Wu KM

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:RNA-seq data of hepatocellular carcinoma (HCC) was analyzed to identify critical genes related to the pathogenesis and prognosis. MATERIALS AND METHODS:Three RNA-seq datasets of HCC (GSE69164, GSE63863 and GSE55758) were downloaded from Gene Expression Omnibus (GEO), while another dataset including 54 HCC ca...

journal_title：European review for medical and pharmacological sciences

authors： Yang MR,Zhang Y,Wu XX,Chen W

更新日期：2016-10-01 00:00:00

abstract：AIM:We aimed to determine the relationship between blood lactate, carboxy-hemoglobin (COHb) levels and the severity of clinical findings in patients with CO poisoning. PATIENTS AND METHODS:Patients over 18 years old and of both gender who were admitted to Emergency Department with the diagnosis of CO poisoning between...

journal_title：European review for medical and pharmacological sciences

authors： Icme F,Kozaci N,Ay MO,Avci A,Gumusay U,Yilmaz M,Satar S

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:Midazolam and sufentanil are common analgesic and sedative drugs, but the effects and mechanisms of the combination of these two drugs on pancreatitis injury have not been fully elucidated. MATERIALS AND METHODS:Rats pancreatitis model were randomly divided into 4 groups, model group, midazolam group, sufent...

journal_title：European review for medical and pharmacological sciences

authors： Zhou H,Zhu ZH,Liu Y,Liu YY

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:Recently, the vital role of circular RNAs is discovered in many diseases, including tumor progression. Non-small cell lung cancer (NSCLC) is one of the most ordinary malignant tumors. The purpose of our study is to detect the potential function of circ_0017247 in NSCLC to offer new biomarkers and targets. PA...

journal_title：European review for medical and pharmacological sciences

authors： Li CH,Wang YB,Chen KB

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:To investigate the protective effect of dexmedetomidine on intracerebral hemorrhage (ICH) mice and the underlying mechanism. MATERIALS AND METHODS:The in vivo ICH model was induced by the injection of autologous blood in C57BL/6 mice. Mice were randomly assigned into control group (no specific treatment) and...

journal_title：European review for medical and pharmacological sciences

authors： Song HL,Zhang SB

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:Colorectal cancer is a common malignant tumor of the digestive tract, and its incidence is closely related to lifestyle inheritance and colorectal adenoma. Circular RNA (circRNA) has been proved to participate in the progression of colorectal cancer cells. Our study aimed to investigate the function and the u...

journal_title：European review for medical and pharmacological sciences

authors： Zhang ZJ,Zhang YH,Qin XJ,Wang YX,Fu J

更新日期：2020-03-01 00:00:00