Abstract:
:Adenoid cystic carcinoma is a rare but aggressive malignant tumor of the lacrimal gland. Mortality rates have been found to be quite high (>50%). This has led to the traditional method of treatment with radical surgery including orbital exenteration and bone resection, followed by external beam radiotherapy to the orbital bed. Despite this aggressive treatment strategy, mortality rates still remain high with only a few reported cases with long-term survival. Recently, several cases of successful treatment of adenoid cystic carcinoma with plaque radiotherapy have been documented. These may show promise of a conservative treatment strategy in selected cases. The authors present a functionally monocular patient with a well-circumscribed adenoid cystic carcinoma that was treated with local excision of the tumor with reverse plaque brachytherapy "boost" to the lacrimal tumor bed followed by a lower dose of radiotherapy to the orbit. The patient is alive and without local recurrence at nearly 4 years.
journal_name
Ophthalmic Plast Reconstr Surgjournal_title
Ophthalmic plastic and reconstructive surgeryauthors
Lewis KT,Kim D,Chan WF,Jaiwatana J,Calcote Cdoi
10.1097/IOP.0b013e3181b8c61dsubject
Has Abstractpub_date
2010-03-01 00:00:00pages
131-3issue
2eissn
0740-9303issn
1537-2677pii
00002341-201003000-00020journal_volume
26pub_type
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journal_title:Ophthalmic plastic and reconstructive surgery
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