Gastroesophageal reflux disease. When antacids aren't enough.

Abstract:

:Gastroesophageal reflux disease is a very common condition that is usually manifested by heartburn or regurgitation. Reflux esophagitis, caused by mucosal exposure to the backflow of caustic gastric contents, is primarily a result of lower esophageal sphincter dysfunction. Diagnostic workup varies but commonly includes esophagoscopy, 24-hour esophageal pH monitoring, and radiography of the upper gastrointestinal tract. Treatment, which progresses from simple life-style changes and antacids to histamine2 receptor antagonists to omeprazole (Prilosec) or surgery, is tailored to individual needs and is generally successful.

journal_name

Postgrad Med

journal_title

Postgraduate medicine

authors

Sutherland JE

doi

10.1080/00325481.1991.11700938

subject

Has Abstract

pub_date

1991-05-15 00:00:00

pages

45-8, 51-3

issue

7

eissn

0032-5481

issn

1941-9260

journal_volume

89

pub_type

杂志文章
  • The place of inhaled corticosteroids in the treatment of chronic obstructive pulmonary disease: a narrative review.

    abstract::Inhaled corticosteroids (ICSs) belong to the armament for treatment of chronic obstructive pulmonary disease (COPD) and as such, they are widely used in real life. This is a narrative review on evidence-based papers published in the English language listed in Medline between 1990 and March 2016 discussing ICS applicat...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.2016.1186487

    authors: Andreeva-Gateva PA,Stamenova E,Gatev T

    更新日期:2016-06-01 00:00:00

  • Problems+Solutions.

    abstract::Readers are invited to submit questions relating to problem cases. Inquiries will be answered by qualified consultants and replies forwarded by mail promptly. Selected problems and solutions are published every month in this section. ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1985.11698867

    authors: Spitzer AR,Berberian DA,Moe JH

    更新日期:1985-02-01 00:00:00

  • Modulation of the gut microbiota: a focus on treatments for irritable bowel syndrome.

    abstract::Irritable bowel syndrome (IBS), which is characterized by recurrent abdominal pain and disordered bowel habits, is one of the most common functional bowel disorders. IBS is a substantial burden on both patient health-related quality of life and healthcare costs. Several pathophysiologic mechanisms have been postulated...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.2017.1383819

    authors: Harris LA,Baffy N

    更新日期:2017-11-01 00:00:00

  • Newer antihypertensive agents.

    abstract::Captopril (Capoten) and minoxidil (Loniten) have recently become generally available for treatment of hypertension, and calcium channel blockers, although not yet officially approved for this indication, clearly have potential as antihypertensive agents. Captopril, the only available inhibitor of angiotensin-convertin...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1983.11698326

    authors: Kaplan NM

    更新日期:1983-01-01 00:00:00

  • Transdermal estrogens in the changing landscape of hormone replacement therapy.

    abstract::Views and clinical practice on hormone replacement therapy (HRT) for postmenopausal women have varied widely over the last several decades. The 1990s showed a dramatic decline in prescribing and only recently are prescription rates increasing again. Use of HRT is first line for women suffering from the symptoms of men...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.2017.1334507

    authors: Beck KL,Anderson MC,Kirk JK

    更新日期:2017-08-01 00:00:00

  • Intensive glycemic control and cardiovascular disease: are there patients who may benefit?

    abstract::Cardiovascular disease (CVD) is the major cause of morbidity and mortality in patients with type 2 diabetes mellitus (T2DM). Recent major publications, such as the Action to Control Cardiovascular Risk in Diabetes trial, the Advance in Diabetes and Vascular Disease: Preterax and Diamicron MR Controlled Evaluation tria...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2011.11.2501

    authors: Chokrungvaranon N,Deer J,Reaven PD

    更新日期:2011-11-01 00:00:00

  • Unusual presentations of gout. Tips for accurate diagnosis.

    abstract::In cases of unusual presentations, such as the three cases described here, gout or gouty arthritis may be misdiagnosed as rheumatoid arthritis, septic arthritis, or other rheumatic conditions and thus inappropriately treated. Microscopic analysis using compensated polarized light and culture of synovial fluid helps di...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.1996.07.20

    authors: Uy JP,Nuwayhid N,Saadeh C

    更新日期:1996-07-01 00:00:00

  • Listerial meningitis and renal allografts: a life-threatening affinity.

    abstract::Two cases of Listeria monocytogenes infection in patients receiving immunosuppressive treatment after kidney transplantation are described. In the first, the infection, which occurred soon after transplantation and was accompanied by signs of mild chronic rejection, was the immediate cause of death. The other case occ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1980.11715622

    authors: Holden FA,Kaczmer JE,Kinahan CC

    更新日期:1980-12-01 00:00:00

  • Fever following abdominal surgery. Unusual infectious causes.

    abstract::Identification of the cause and subsequent specific therapy are indicated for those prolonged or relapsing fevers that follow abdominal surgery. On rare occasions, these fevers can be attributed to potentially life-threatening occult infections, including maxillary sinusitis, acute cholecystitis, antibiotic-related ps...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1986.11699288

    authors: Gleckman RA,Roth RM

    更新日期:1986-02-01 00:00:00

  • Dermatoses: common in blacks.

    abstract::Some skin disorders are more common in blacks than in whites or are so rare in whites as to be almost peculiar to blacks. Pigmentary abnormalities, either dark or light spots, often occur in association with inflammatory skin diseases. Curvature of the hair follicle is thought to be at the root of two other painful co...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1977.11712223

    authors: Kenney JA Jr

    更新日期:1977-06-01 00:00:00

  • Bronchiectasis in adults: a review.

    abstract::Bronchiectasis is characterized by permanent, abnormal dilation of the bronchi with chronic inflammation and infection. Bronchiectasis is either caused by or associated with several systemic disorders, and in a significant number of cases, the underlying etiology remains unidentified and is subsequently referred to as...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2008.09.1912

    authors: Lazarus A,Myers J,Fuhrer G

    更新日期:2008-09-01 00:00:00

  • Serologic markers: impact on early diagnosis and disease stratification in inflammatory bowel disease.

    abstract::Inflammatory bowel disease (IBD) is difficult to diagnose, and differentiating between ulcerative colitis (UC) and Crohn's disease (CD) can be challenging. Overlapping symptoms of UC and CD often delay diagnosis, despite availability of endoscopic, radiologic, and histologic tools. This delay in diagnosis is quite com...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2010.07.2184

    authors: Arai R

    更新日期:2010-07-01 00:00:00

  • The balloon-tipped thermodilution catheter. Aspects of its clinical utility.

    abstract::The balloon-tipped thermodilution catheter (BTTC) is an expensive, labor-intensive technology that has moderate risks. The sensitivity and specificity of the three principal tests that it can perform have not yet been well defined for different patient groups. The BTTC allows the acquisition of mixed venous blood, fro...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1986.11699383

    authors: Desbiens NA

    更新日期:1986-05-01 00:00:00

  • Oral anticoagulant therapy: practical aspects of management.

    abstract::Careful attention to the practical aspects of oral anticoagulant therapy can improve patient compliance and lessen the risk of bleeding complications. A variety of risk factors for bleeding associated with oral anticoagulant therapy have been defined and should be assessed before initiating therapy. Recent investigati...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Brigden ML

    更新日期:1996-06-01 00:00:00

  • Treating dysthymia and minor depression in primary care.

    abstract::In the fast-paced setting of primary care, it is difficult to detect psychiatric disorders, especially the more subtle disorders, such as minor depression and dysthymia. In cases of dysthymia, in particular, the patients themselves may not even have a sense that anything medically treatable is wrong; they feel as thou...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.3810/pgm.11.2003.suppl29.159

    authors: David AK

    更新日期:2003-11-01 00:00:00

  • Iron deficiency and anemia of chronic disease. Clues to differentiating these conditions.

    abstract::Iron deficiency occurs when the body's iron stores are exhausted. The source of blood loss leading to iron deficiency must be identified in all cases. Anemia of chronic disease generally results from an infectious, inflammatory, or malignant process. However, in some reported cases, no such process could be identified...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1992.11701469

    authors: Mohler ER Jr

    更新日期:1992-09-15 00:00:00

  • Advances in interventional radiology. The search for less invasive management sparks new approaches.

    abstract::Many new, minimally invasive interventional radiology procedures are now viable alternatives to traditional invasive therapy. The radiology procedures can often be performed in the outpatient setting, and although expensive technology may be required, the overall cost to the patient may be lower in the long run. Endov...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2001.06.958

    authors: Montgomery ML,Sullivan JP

    更新日期:2001-06-01 00:00:00

  • Reversal agents in development for the new oral anticoagulants.

    abstract::The new oral anticoagulants have many advantages over vitamin K antagonists, but they are still associated with a troublesome incidence of major bleeding. Additionally, the absence of a reversal agent for the new oral anticoagulants is a barrier to their more widespread use. Currently, there are 3 potential reversal a...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2014.11.2829

    authors: Costin J,Ansell J,Laulicht B,Bakhru S,Steiner S

    更新日期:2014-11-01 00:00:00

  • When to worry about hypoglycemia.

    abstract::The important causes of hypoglycemia unrelated to known diabetes are relatively few. Postprandial hypoglycemia is a relatively benign disorder. Fasting hypoglycemia is more serious and may be caused by metabolic disturbances or tumors. Several hereditary disorders cause hypoglycemia in infants and must be diagnosed an...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1990.11716369

    authors: Felicetta JV

    更新日期:1990-07-01 00:00:00

  • Rapid evaluation of comatose patients.

    abstract::Coma is a common, life-threatening medical problem encountered by primary care physicians. The principles of emergency management mandate that adequate oxygenation, blood flow, and supplementation with thiamine and glucose be given to the brain before a thorough diagnostic evaluation is undertaken. Knowledge of the us...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1990.11716346

    authors: Alguire PC

    更新日期:1990-05-01 00:00:00

  • Evaluation of the bleeding patient.

    abstract::The evaluation of the bleeding patient starts with the integration of data from the history and physical examination. From this results either one probable explanation that can easily be substatniated by laboratory studies or, as more commonly occurs in practice, several possibilities that are reasonable and must be i...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1977.11712257

    authors: Marengo-Rowe AJ,Leveson JE

    更新日期:1977-07-01 00:00:00

  • Deficiency of vitamins A, B, and C.

    abstract::Preview Although specific vitamin deficiency syndromes are relatively rare in the United States, primary care physicians may encounter them in elderly patients and persons who consume minimal diets. Knowledge of such deficiencies is crucial in the evaluation of these patients. The authors discuss manifestations of def...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1990.11704615

    authors: Skelton WP,Skelton NK

    更新日期:1990-03-01 00:00:00

  • Educational needs in the diagnosis and management of pediatric functional constipation: a US survey of specialist and primary care clinicians.

    abstract:OBJECTIVES:The goal of this study was to identify opportunities among gastroenterologists and gastroenterology nurse practitioners (NPs)/physician assistants (PAs) for continuing medical education (CME) related to functional constipation. METHODS:An online, case-vignette survey was designed to identify and quantify pr...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.2018.1464364

    authors: Barnes J,Coleman B,Hwang S,Stolic A,Bousvaros A,Nurko S,Salinas GD

    更新日期:2018-05-01 00:00:00

  • The new hepatitis B vaccine. How, when, and why to use it.

    abstract::A hepatitis B vaccine derived from the plasma of carriers of hepatitis B virus has recently become generally available in the United States. Its use is recommended in groups considered to be at high risk of hepatitis B because of their exposure to potentially infectious blood, saliva, or semen. Experience in more than...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1983.11697828

    authors: Kutcher WL

    更新日期:1983-05-01 00:00:00

  • New concepts in treatment of chronic persistent asthma. Using a stepwise protocol to control inflammation.

    abstract::Asthma continues to cause unacceptably high rates of disability and death, largely because the severity of disease is underestimated and patients are inadequately educated about their disease. When patients understand what happens during an asthma attack and its aftermath, they are more likely to notice important symp...

    journal_title:Postgraduate medicine

    pub_type: 指南,杂志文章,评审

    doi:10.1080/00325481.1991.11701034

    authors: Rumbak MJ

    更新日期:1991-09-01 00:00:00

  • Thyroid dysfunction in the severely ill and elderly.

    abstract::Preview Manifestations of thyroid dysfunction may be totally misleading in severely ill and elderly patients, often confounding clinical diagnosis. To prevent undue morbidity and mortality in these patients, appropriate selection and accurate interpretation of thyroid function tests are crucial. In this article, Dr Is...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1993.11945709

    authors: Isley WL

    更新日期:1993-09-01 00:00:00

  • Eating disorders in adolescents with type 1 diabetes. A closer look at a complicated condition.

    abstract::The cultural drive to be thin can lead to eating disorders in many women and girls. In adolescent females with diabetes, the increased focus on eating and the weight gain associated with good glycemic control likely increase their susceptibility to abnormal eating. It is clear that nonspecified and subthreshold eating...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2001.04.910

    authors: Hoffman RP

    更新日期:2001-04-01 00:00:00

  • Massive blood loss in trauma patients. The benefits and dangers of transfusion therapy.

    abstract::In acutely injured patients, recognition of profound shock may be difficult initially. Ensuring adequate oxygenation, restoring intravascular volume, and controlling ongoing blood loss are key principles of treatment in these patients. Additionally, an appreciation for and recognition of the possible adverse consequen...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Phillips GR 3rd,Kauder DR,Schwab CW

    更新日期:1994-03-01 00:00:00

  • Psychiatry: unresolved grief. Clinical considerations.

    abstract::Unresolved grief refers either to the absence or to the prolongation of normal grief. It is identified by (1) painful response to recall of the deceased, (2) realization of not having accepted the loss or of not being able to grieve, and (3) unaccountable depression, emergence of medical symptoms on the anniversary of...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1976.11714374

    authors: DeVaul RA,Zisook S

    更新日期:1976-05-01 00:00:00

  • Hematuria. When is it cause for alarm?

    abstract::The urine of less than 3% of healthy persons shows more than three red cells per high-power field, which is about the limit of sensitivity of test strips for occult blood. Even minimal hematuria may herald serious problems and must be investigated. Common causes include infection, urethritis, and urethrotrigonitis (25...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1987.11699979

    authors: Brown DC

    更新日期:1987-09-15 00:00:00