Abstract：
:Cerebrovascular autoregulation (CA) is often impaired following traumatic brain injury. Established technologies and metrics used to assess CA are invasive and conducive for measurement, but not for continuous monitoring. We developed a trans-ocular brain impedance (TOBI) method that may provide non-invasive and continuous indices to assess CA. In this study, we monitored impedance metrics such as respiratory-induced impedance amplitude changes (dz) as well as a novel impedance index (DZx), which is a moving Pearson correlation between mean arterial pressure (MAP) and dz. Yorkshire swine were instrumented to continuously record ICP, MAP, and cerebral blood flow (CBF). TOBI was recorded by placement of standard ECG electrodes on closed eyelids and connected to a data acquisition system. MAP, ICP and CBF were manipulated utilizing an intravenous vasopressor challenge. TOBI indices (dz and DZx) were compared to the hemodynamic indicators as well as pressure reactivity index (PRx). During the vasopressor challenge, dz was highly correlated with ICP, CPP, and CBF (r = < - 0.49, p < 0.0001). ICP, CPP, and CBF had a mean percent increase (standard deviation) from baseline of 29(23.2)%, 70(25)%, and 37(72.6)% respectively while dz decreased by 31(15.6)%. Receiver operator curve test showed high predictive performance of DZx when compared to PRx with area under the curve above 0.86, with high sensitivity and specificity. Impedance indices appear to track changes in PRx and hemodynamics that affect cerebral autoregulation. TOBI may be a suitable less invasive surrogate to PRx and capable of tracking cerebral autoregulation.
journal_name
J Clin Monit Computjournal_title
Journal of clinical monitoring and computingauthors
Tiba MH,McCracken BM,Leander DC,Colmenero CI,Cummings BC,Greer NL,Picton P,Williamson CA,Ward KRdoi
10.1007/s10877-020-00556-1subject
Has Abstractpub_date
2020-07-14 00:00:00eissn
1387-1307issn
1573-2614pii
10.1007/s10877-020-00556-1pub_type
杂志文章abstract：:Monitors evaluating the electroencephalogram (EEG) to determine depth of anaesthesia use spectral analysis approaches for analysis windows up to 61.5 s as well as additional smoothing algorithms. Stationary EEG is required to reliably apply the index algorithms. Because of rapid physiological changes, artefacts, etc.,...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10877-014-9553-y
更新日期：2014-12-01 00:00:00
abstract：:Perioperative goal-directed therapy is considered to improve patient outcomes after high-risk surgery. The association of compliance with perioperative goal-directed therapy protocols and postoperative outcomes is unclear. The purpose of this study is to determine the effect of protocol compliance on postoperative out...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-020-00585-w
更新日期：2020-09-12 00:00:00
abstract：:Studies reveal that the false alarm rate (FAR) demonstrated by intensive care unit (ICU) vital signs monitors ranges from 0.72 to 0.99. We applied machine learning (ML) to ICU multi-sensor information to imitate a medical specialist in diagnosing patient condition. We hypothesized that applying this data-driven approa...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-019-00307-x
更新日期：2020-04-01 00:00:00
abstract：:Bioreactance is a novel non-invasive method for cardiac output measurement that involves the analysis of blood flow-dependent changes in the phase shifts of electrical currents applied across the chest. The present study (1) compared resting and exercise cardiac outputs determined by bioreactance and bioimpedance meth...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-012-9334-4
更新日期：2012-04-01 00:00:00
abstract：:The recently developed technique for measuring cutaneous mitochondrial oxygen tension (mitoPO2) by means of the Protoporphyrin IX-Triplet State Lifetime Technique (PpIX-TSLT) provides new opportunities for assessing mitochondrial function in vivo. The aims of this work were to study whether cutaneous mitochondrial mea...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-014-9628-9
更新日期：2015-08-01 00:00:00
abstract：:The American Society of Neurophysiological Monitoring (ASNM) is developing position statements aimed at assisting practitioners and others in making decisions regarding neurophysiological monitoring practice. This paper describes the procedures used in drafting these documents. ...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-005-9000-1
更新日期：2006-02-01 00:00:00
abstract：:Hypothermia is a common perioperative complication. To prevent perioperative hypothermia amongst other things electrical heating mattresses are used. We have made an observation with the use of an electrical heating mattress that may confuse users. In this case the ECG monitoring suddenly showed spikes that looked lik...
journal_title：Journal of clinical monitoring and computing
pub_type： 信件
doi：10.1007/s10877-020-00520-z
更新日期：2020-07-15 00:00:00
abstract：:Amidst controversy about methodology and safety, intraoperative neurophysiology has entered a new era of increasingly routine transcranial and direct electrical brain stimulation for motor evoked potential (MEP) monitoring. Based on literature review and illustrative clinical experience, this tutorial aims to present ...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章,评审
doi：10.1007/s10877-006-9033-0
更新日期：2006-10-01 00:00:00
abstract：:An intraoperative automated closed-loop system for goal-directed fluid therapy has been successfully tested in silico, in vivo and in a clinical case-control matching. This trial compared intraoperative cardiac output (CO) in patients managed with this closed-loop system versus usual practice in an academic medical ce...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10877-018-0106-7
更新日期：2018-12-01 00:00:00
abstract：:Hypotension subsequent to spinal anesthesia occurs in a significant number of parturients undergoing lower segment caesarian section. Currently available methods to predict the incidence of hypotension, its severity and the outcome are sub-optimal. Many workers have used basal heart rate as one of the predictors. But ...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-016-9906-9
更新日期：2017-08-01 00:00:00
abstract：:The respiration rate (RR) is a vital sign in physiological measurement and clinical diagnosis. RR can be measured using stretchable and wearable strain gauge sensors which detect the respiratory movements in the abdomen or thorax areas caused by volumetric changes. In different body locations, the accuracy of RR detec...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-020-00481-3
更新日期：2020-02-22 00:00:00
abstract：:The American Society of Anesthesiologist recommends peripheral physiological monitoring during general anesthesia, which offers no information regarding the effects of anesthetics on the brain. Since no "gold standard" method exists for this evaluation, such a technique is needed to ensure patient comfort, procedure q...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-017-9998-x
更新日期：2018-02-01 00:00:00
abstract：:Numerous factors could contribute to sleep disturbances in women with breast cancer. We hypothesized that stellate ganglion block (SGB) during surgery would preserve sleep after surgery and increase intraoperative regional cerebral oxygen saturation (rSO2) on the blocked side in patients undergoing breast cancer surge...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10877-017-0074-3
更新日期：2018-10-01 00:00:00
abstract：OBJECTIVE:Several studies suggest that parameters derived from bispectral analysis of the EEG can be used to characterize specific cortical activation states represented by non linear interaction between brain electrical oscillations. For example, it was shown that so-called bispectral indices can be used to assess the...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1023/a:1016362209175
更新日期：2002-02-01 00:00:00
abstract：:The utility of capnography to detect early respiratory compromise in surgical patients after anesthesia is unclear due to limited prospective data. The purpose of this trial was to determine the frequency and duration of capnography-detected respiratory adverse events in the post-anesthesia care unit (PACU). In this p...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-019-00333-9
更新日期：2020-06-01 00:00:00
abstract：:This study aimed to investigate and compare the performance of the algorithms contained in the newest generation of pulse oximeters (Masimo SET in IVY2000, Nellcor Oxismart N-3000, Agilent M3 rev. B) against a traditional pulse oximeter (Agilent CMS rel. A.0). The benchmark was performed in an efficient and reproducib...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1023/a:1011420228523
更新日期：2000-01-01 00:00:00
abstract：:We assessed the effect of re-calibration time on cardiac output estimation and trending performance in a retrospective analysis of an intensive care unit patient population using error grid analyses. Paired thermodilution and arterial blood pressure waveform measurements (N = 2141) from 222 patient records were extrac...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-015-9749-9
更新日期：2016-10-01 00:00:00
abstract：:Changes have been made to the AnaConDa device (Sedana Medical, Stockholm, Sweden), decreasing its size to reduce dead space and carbon dioxide (CO2) retention. However, this also involves a decrease in the surface area of the activated carbon filter. The CO2 elimination and sevoflurane (SEV) reflection of the old devi...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-019-00285-0
更新日期：2020-02-01 00:00:00
abstract：:Central venous cannulation is a commonly preformed procedure in many branches of medicine, particularly in anaesthesia and intensive care medicine. The purpose of this study was to compare the landmark-guided technique to the ultrasound-guided technique for internal jugular vein cannulation in cardiovascular surgery p...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10877-014-9585-3
更新日期：2015-02-01 00:00:00
abstract：OBJECTIVE:To compare expert-generated textual summaries of physiological data with trend graphs, in terms of their ability to support neonatal Intensive Care Unit (ICU) staff in making decisions when presented with medical scenarios. METHODS:Forty neonatal ICU staff were recruited for the experiment, eight from each o...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-005-0879-3
更新日期：2005-06-01 00:00:00
abstract：:The use of sedation for diagnostic procedures including gastrointestinal endoscopy is rapidly growing. Recovery of cognitive function after sedation is important because it would be important for most patients to resume safe, normal life soon after the procedure. Computerized tests have shown being accurate descriptor...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-018-0134-3
更新日期：2019-02-01 00:00:00
abstract：BACKGROUND:The value of the impedance cardiography (IC) method for measuring cardiac output (CO) with the subject in the left lateral position has not yet been established. We compared the CO after a 30 degrees head-up tilt with the subjects in the supine and left lateral position. METHODS:Thirty healthy young volunte...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1023/a:1009968513512
更新日期：1999-12-01 00:00:00
abstract：:With the AnaConDa™ and the MIRUS™ system, volatile anesthetics can be administered for inhalation sedation in intensive care units. Instead of a circle system, both devices use anesthetic reflectors to save on the anesthetic agent. We studied the efficiency of desflurane reflection with both devices using different ti...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-016-9902-0
更新日期：2018-08-01 00:00:00
abstract：OBJECTIVE:Awareness with recall is a rare but serious complication of general anaesthesia with an incidence ranging from 0.1%-0.7%. In the absence of a reliable depth-of-anaesthesia monitor, attempts have been made to predict awareness from intraoperative haemodynamic monitoring data, with little success. Artificial ne...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1023/a:1015426015547
更新日期：2002-01-01 00:00:00
abstract：:An ongoing issue in vascular medicine is the measure of the blood flow. Catheterization remains the gold standard measurement method, although non-invasive techniques are an area of intense research. We hereby present a computational method for real-time measurement of the blood flow from color flow Doppler data, with...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-016-9953-2
更新日期：2017-12-01 00:00:00
abstract：:The test of the inner tube integrity is an important checklist prior to the safe use of Bain's breathing system. This is because the major concern with the use of Bain's circuit is the potential malfunctioning of the circuit due to avulsion of the inner fresh gas delivery tube at the machine end which will turn the ou...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-009-9212-x
更新日期：2010-02-01 00:00:00
abstract：INTRODUCTION:Patients undergoing lung resection are vulnerable to fluid overhydration. Recently, goal-directed fluid therapy using transoesophageal Doppler monitoring (TDM) has been shown to improve postoperative clinical outcome. The aim of this study was to assess the feasibility of TDM during open-chest procedures f...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-008-9144-x
更新日期：2008-10-01 00:00:00
abstract：OBJECTIVES:Bioreactance, the analysis of intrabeat variations in phase of a transthoracic voltage in response to an applied high frequency transthoracic current, was recently introduced for noninvasive cardiac output measurement (NICOM). We evaluated NICOM compared to thermo- dilution (TD) in several clinical settings....
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章,多中心研究
doi：10.1007/s10877-008-9112-5
更新日期：2008-04-01 00:00:00
abstract：OBJECTIVE:Mixtures of helium and oxygen are regaining a place in the treatment of obstruction of the upper and lower respiratory tract. The parenchymal changes during the course of IRDS or ARDS may also benefit from the reintroduction of helium/oxygen. In order to monitor and document the effect of low-density gas mixt...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1023/a:1009978816071
更新日期：1998-08-01 00:00:00
abstract：:The aim was, to identify an estimate of left ventricular contractility derived from the aortic pressure wave without load changing manoeuvres. For this purpose, left ventricular contractility was assessed with several aortic pressure wave form derived parameters and was compared to standard parameters of left ventricu...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-008-9145-9
更新日期：2008-10-01 00:00:00
