Abstract:
:The present study examines the association between asbestos-related pleural plaques and lung function in a group of workers with occupational exposure to asbestos. Exposure, smoking, and respiratory histories, chest radiographs, flow-volume loops, and single breath DLCOs were obtained on 383 railroad workers. A score based on the ILO-1980 classification system was used to quantify the extent of plaquelike thickening. In order to eliminate potential confounders, we excluded from final analysis subjects with diffuse pleural thickening (n = 10) or small irregular opacities classified as profusion 0/1 or greater (n = 6) on chest radiograph. Definite pleural plaques were observed in 22.6%. The single breath DLCO was similar in the groups with and without plaques (p = 0.0550). Decrement in FVC and the occurrence of pulmonary restriction were associated with the presence of definite plaques (p = 0.0306 and 0.0431, respectively) and with quantitative pleural score (p = 0.0135 and 0.0126), controlling for duration of asbestos exposure and smoking. A test for trend revealed an association between level of diagnostic certainty (none, suspect, definite) for pleural plaques and these measures of lung function (p less than 0.02). Our findings reveal an association between asbestos-related pleural plaques and decrement in lung function as measured by FVC and criteria for pulmonary restriction.
journal_name
Am J Ind Medjournal_title
American journal of industrial medicineauthors
Oliver LC,Eisen EA,Greene R,Sprince NLdoi
10.1002/ajim.4700140604subject
Has Abstractpub_date
1988-01-01 00:00:00pages
649-56issue
6eissn
0271-3586issn
1097-0274journal_volume
14pub_type
杂志文章abstract::There have long been case reports linking silica exposure to a variety of autoimmune diseases (systemic sclerosis, rheumatoid arthritis, lupus, chronic renal disease). Evidence of this association in larger epidemiologic studies has been increasing in the last decade. We summarize this evidence here, and present some ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/ajim.4700280505
更新日期:1995-11-01 00:00:00
abstract:BACKGROUND:An investigation of a small private agate mill was prompted by an agate worker who presented with silicosis in Guangzhou, China, in December 1998. METHODS:The work processes and records of dust measurements of the mill were examined. The mean total dust concentrations ranged from 3.0 to 9.9 mg/m3; 86-88% of...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.1074
更新日期:2001-07-01 00:00:00
abstract::To investigate the effects of styrene exposure on peripheral, central, and autonomic nervous system functions in man, we measured the distribution of nerve conduction velocities (DCV), short-latency somatosensory evoked potentials (SSEP), and variability in electrocardiographic R-R interval (CVRR) as well as conventio...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700200609
更新日期:1991-01-01 00:00:00
abstract::Response rates were examined in a prospective epidemiologic study of individuals, mostly farmers, from Iowa and North Carolina seeking a pesticide applicator license during the period from 1994 through 1996. In the first year of enrollment 16,535 farmers (representing 77% of eligible farmer applicators) enrolled in th...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199702)31:2<233::aid-ajim1
更新日期:1997-02-01 00:00:00
abstract:BACKGROUND:The occupational lung cancer risk in manufacturing and repair of shoes was studied by pooling of two major case-control studies from Germany. METHODS:Some 4184 incident hospital-based cases of primary lung cancer and 4253 population controls, matched for sex, age, and region of residence were intensively in...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(200006)37:6<575::aid-ajim1
更新日期:2000-06-01 00:00:00
abstract::The cause-specific mortality (1940-1993) of 2,985 male workers employed in three oil refineries was examined using a proportionate mortality study design. Separate analyses were undertaken by race, refinery, employment status (active and retired), and time since entry into the Oil, Chemical, and Atomic Workers (OCAW) ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199804)33:4<327::aid-ajim3
更新日期:1998-04-01 00:00:00
abstract:BACKGROUND:Polyvinyl chloride plastics (PVC), made flexible through the addition of di-2-ethylhexyl phthalate (DEHP), are used in the production of a wide array of medical devices. From the late 1960s, leaching of DEHP from PVC medical devices and ultimate tissue deposition have been documented. METHODS:A critical rev...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,meta分析
doi:10.1002/1097-0274(200101)39:1<100::aid-ajim10>3.0.
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:Farmworkers in the US largely consist of young undocumented Hispanics with a median education of 6 years and limited English skills. The High Plains Intermountain Center for Agricultural Health and Safety bilingual pesticide risk reduction program, which complied with the Worker Protection Standard for migra...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20136
更新日期:2005-03-01 00:00:00
abstract:BACKGROUND:Epichlorohydrin (ECH) is a strong irritant of the eyes, respiratory tract, and skin. The aims of this study were to examine the dose-response relationship between observed abnormal pulmonary function tests and respiratory tract irritation symptoms among epichlorohydrin-exposed workers in Taiwan. METHODS:A t...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.10177
更新日期:2003-04-01 00:00:00
abstract:BACKGROUND:The Limulus amebocyte lysate (LAL) assay may underestimate endotoxins because only soluble endotoxins are determined. The solubility of endotoxins was, therefore, studied in two species of Gram-negative bacteria. METHODS:Cultures were grown in serum broth, cells were harvested by centrifugation and washed i...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20089
更新日期:2004-10-01 00:00:00
abstract::This case-referent study assesses occupational risk factors associated with lung cancer, utilizing colon and rectum cancer referents. Complete occupational and tobacco use histories were obtained by telephone interview for 5,935 incident lung cancer cases and 3,956 incident colon and rectum cancer referents. The analy...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700190510
更新日期:1991-01-01 00:00:00
abstract::A case-control study on work with video screen equipment during pregnancy has been made for three cohorts of women, identified with the aid of occupational codes in the census, linked to the Medical Birth Registry and a registry containing information on women hospitalized for spontaneous abortion. Five hundred and tw...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700090507
更新日期:1986-01-01 00:00:00
abstract:OBJECTIVES:To examine disparities between job control scores in Black and White subjects and attempt to discern whether self-rated low job control in Blacks may arise from structural segregation into different jobs, or represents individual responses to race-based discrimination in hiring or promotion. METHODS:Data fr...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22255
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:The purpose of the study was to evaluate trends in occupational lead exposures throughout U.S. industry after the establishment of the general industry lead standard in 1978 and the construction industry standard in 1993. METHODS:Lead exposure measurements collected by the Occupational Safety and Health Adm...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20008
更新日期:2004-06-01 00:00:00
abstract:BACKGROUND:The aim of the study was to assess the prevalence of hand paresthesias (HP) and their relationship with pruning activities. METHODS:A cross-sectional study was conducted among 537 workers pruning grapevines in the region of Champagne. All workers completed a questionnaire about nocturnal HP and musculoskele...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.10012
更新日期:2001-12-01 00:00:00
abstract:BACKGROUND:Metal fabrication workers experience high rates of traumatic occupational injuries. Machine operators in particular face high risks, often stemming from the absence or improper use of machine safeguarding or the failure to implement lockout procedures. METHODS:The National Machine Guarding Program (NMGP) wa...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22514
更新日期:2015-11-01 00:00:00
abstract::An occupational injury surveillance project was conducted in 15 of Iowa's 99 counties. Trained abstractors reviewed the medical records of persons admitted for trauma to hospitals during 1983. Based on these chart reviews, subsequent mail-out questionnaires and phone contacts were made, and rate estimates for occupati...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700180213
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:The purpose of Pre-Adult Latency Study was to evaluate lung findings among adults who had been environmentally exposed to Libby Amphibole only during childhood and adolescence. METHODS:Recruitment was restricted to volunteers who attended primary and/or secondary school, lived in Libby, MT, prior to age 23 ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22674
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:To compare fatal and hospitalized nonfatal work-related traumatic injuries by occupation and cause. METHODS:Fatal and hospitalized nonfatal injuries occurring from 1991-1995 were identified from Washington State workers' compensation claims data. Nonfatal injuries were classified as severe if they had at lea...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199908)36:2<317::aid-ajim1
更新日期:1999-08-01 00:00:00
abstract:BACKGROUND:Evidence regarding the unequal burden of occupational injuries between workers employed by temporary agencies and those in standard employment arrangements is unclear. Studies range from no significant differences in risk to substantial increased risk for temporary workers. The purpose of this study is to co...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20728
更新日期:2010-02-01 00:00:00
abstract:BACKGROUND:Previous studies of workers' compensation claims for low back pain (LBP) have revealed that the preponderance of disability is borne by a fraction of cases. However, less is known regarding the influence of occupational factors on these extreme conditions. METHODS:Workers' compensation claims (n=107,867) fo...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(200005)37:5<558::aid-ajim1
更新日期:2000-05-01 00:00:00
abstract::The effects of aluminum on the pulmonary function of aluminum workers were investigated in this study. Serum aluminum levels and spirometry were measured in 55 male workers and 30 male controls. The mean serum aluminum level of workers (72.7 +/- 9.9 ng/ml) was significantly high compared to that of controls, indicatin...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199803)33:3<305::aid-ajim1
更新日期:1998-03-01 00:00:00
abstract::The evidence from animal studies indicates that organic extracts of diesel particulate are mutagenic and carcinogenic. Of four animal inhalation studies, two have been positive and two have been largely negative. The most recent data indicate that inhalation studies may be positive only with high doses of exhaust. Hum...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700100208
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:Previous epidemiological studies investigating modification of organophosphate (OP) neurotoxicity by xenobiotic metabolizing enzymes (XMEs) polymorphisms have produced inconsistent results. METHODS:A cross-sectional study of 301 emerging farmers was conducted. Neurotoxicity testing included forward and back...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22790
更新日期:2018-01-01 00:00:00
abstract::Incinerator workers are exposed to many toxic compounds, most notably heavy metals. We evaluated medical and exposure monitoring data of an actively employed cohort of Philadelphia incinerator workers following an Agency for Toxic Substances and Disease Registry site survey and National Institute for Occupational Safe...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700220309
更新日期:1992-01-01 00:00:00
abstract::In view of the increasing incidence of diseases such as gastritis and ulcers in workers exposed to noise, we assessed whether noise does in fact affect gastric secretion. Then, considering the conflicting findings published on the effects of noise on gastric secretion, we also investigated whether the response was rel...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700260310
更新日期:1994-09-01 00:00:00
abstract:BACKGROUND:Hotel room cleaners have physically demanding jobs that place them at high risk for shoulder pain. Psychosocial work factors may also play a role in shoulder pain, but their independent role has not been studied in this group. METHODS:Seventy-four percent (941 of 1,276) of hotel room cleaners from five Las ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20832
更新日期:2010-07-01 00:00:00
abstract::In order to estimate rates and identify risk factors for assaults on employees of a state psychiatric hospital, we examined workers' compensation claims, hospital-recorded incident reports, and data collected in a survey of ward staff. Results revealed 13.8 workers' compensation claims due to assault per 100 employees...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199701)31:1<92::aid-ajim14
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Work-related injuries in commercial fishing are of concern internationally. To better identify the causes of injury, this study coded occupational injuries by working processes in commercial fishing for fresh market fish. METHODS:A classification system of the work processes was developed by participation i...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20163
更新日期:2005-06-01 00:00:00
abstract::Several studies on the mortality of chemists have revealed a lower overall mortality but an excess of deaths from certain diseases, in particular, cancers. This study determined the causes of mortality of 4,012 chemists among 14,884 members of The Royal Society of Chemistry who were followed for a period of 25 years. ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700230409
更新日期:1993-04-01 00:00:00