What is new with hand hygiene?

abstract：PURPOSE OF REVIEW:The aim of this review is to summarize recent developments in our understanding of the modifiable behavioural and biological factors contributing to the transmission of genital herpes simplex infection, and the limited data on the use of antiviral agents for reducing transmission risk in serodiscordan...

journal_title：Current opinion in infectious diseases

authors： Patel R

更新日期：2004-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Modeling of antibiotic resistance in pathogenic bacteria responsible for human disease has developed considerably over the last decade. Herein, we summarize the main published studies to illustrate the contribution of models for understanding both within-host and population-based phenomena. We then su...

journal_title：Current opinion in infectious diseases

authors： Opatowski L,Guillemot D,Boëlle PY,Temime L

更新日期：2011-06-01 00:00:00

abstract：:The sequence of the Treponema pallidum genome was completed in July 1998, yielding a wealth of new information regarding the enigmatic spirochete that causes syphilis and related treponematoses. By providing the sequences and predicted functions of over 1000 genes, the genome sequence will greatly facilitate research ...

journal_title：Current opinion in infectious diseases

authors： Norris SJ,Weinstock GM

更新日期：2000-02-01 00:00:00

abstract：PURPOSE OF REVIEW:We review the potential new diagnostic tools for determining the cause of pneumonia in the setting of community-acquired infection after outlining the limitation of currently available tests. RECENT FINDINGS:A number of new tools are on the horizon with the potential to overcome the problems of exist...

journal_title：Current opinion in infectious diseases

authors： Basnayake TL,Waterer GW

更新日期：2015-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Antimicrobial resistance (AMR) is a threat to global health and new approaches to combating AMR are needed. Use of machine learning in addressing AMR is in its infancy but has made promising steps. We reviewed the current literature on the use of machine learning for studying bacterial AMR. RECENT FI...

journal_title：Current opinion in infectious diseases

authors： Macesic N,Polubriaginof F,Tatonetti NP

更新日期：2017-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The emergence of 2009 pandemic H1N1 influenza A (pH1N1) has provided a unique challenge to influenza control in healthcare settings. We provide an overview of the early lessons from the 2009 pandemic. RECENT FINDINGS:The modes of influenza transmission and their contributions to the development of in...

journal_title：Current opinion in infectious diseases

authors： Carlson AL,Budd AP,Perl TM

更新日期：2010-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Fungal infections are prevalent in very low birthweight (<1500 g) infants and are associated with significant morbidity and mortality. A better understanding of the adherence factors, molecular diagnostics and risk factors for invasive fungal infection are important in treatment and prevention. RECEN...

journal_title：Current opinion in infectious diseases

authors： Kaufman D

更新日期：2004-06-01 00:00:00

abstract：PURPOSE OF REVIEW:As the evidence for two-drug regimens (2DR) for HIV treatment accumulates and 2DR start to enter consensus guidelines, this review covers the history, rationale and current evidence for 2DR in first-line and switch settings. RECENT FINDINGS:Until recently, most evidence for 2DR was for boosted protea...

journal_title：Current opinion in infectious diseases

authors： Waters L,Church H

更新日期：2020-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to provide an update of nonantibiotic therapies for acute gastroenteritis (AGE), focusing on antiemetics and probiotics. RECENT FINDINGS:The mainstay of therapy for nonsevere AGE remains oral rehydration therapy (ORT). Recent randomized controlled trials and metaanalyses hav...

journal_title：Current opinion in infectious diseases

authors： Funk A,Schnadower D,Freedman SB

更新日期：2020-10-01 00:00:00

abstract：:The implementation of surveillance systems for HIV and of large cohort studies have allowed for the construction of models that more accurately describe the HIV epidemic. This review focuses on changes in the epidemiological pattern, and the effect of changes in behaviour and of antiretroviral therapy. ...

journal_title：Current opinion in infectious diseases

authors： Greco D

更新日期：1998-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Genital Chlamydia trachomatis is common among young, sexually active people. Infections are most often asymptomatic but have potential long-term consequences for female reproductive health. The link between C. trachomatis and ectopic pregnancy is mainly based on early seroepidemiological case-control ...

journal_title：Current opinion in infectious diseases

authors： Bakken IJ

更新日期：2008-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Several attempts have been made to combine drugs for treating visceral leishmaniasis, but only recently have effective drugs become available and combinations been tested systematically. RECENT FINDINGS:Sequential treatments with liposomal amphotericin B followed by miltefosine or paromomycin (as sho...

journal_title：Current opinion in infectious diseases

authors： Olliaro PL

更新日期：2010-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Skin and soft tissue infections (SSTIs) in patients with hematological malignancies are frequent, but dedicated epidemiological studies are limited. The aim of this review is to provide updated description of the main etiological agents, differential diagnosis, and treatment. RECENT FINDINGS:In addit...

journal_title：Current opinion in infectious diseases

authors： Ungaro R,Mikulska M

更新日期：2020-04-01 00:00:00

abstract：:Infections caused by Candida spp. are frequent and serious in oncology patients. Over the past decade, the introduction of azole antifungals as prophylactic agents, and other factors have caused a shift in the species of Candida that cause infection. During the period under review (June 1999 to June 2000), several stu...

journal_title：Current opinion in infectious diseases

authors： Marr KA

更新日期：2000-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Illicit drug use before or during sex - known as sexualized drug use (colloquially 'chemsex' or 'party and play') - has evolved as novel psychoactive substances have entered the market in many parts of the world. Here, we review key conceptual issues in associations between illicit drug use and sexual...

journal_title：Current opinion in infectious diseases

authors： Melendez-Torres GJ,Bourne A

更新日期：2016-02-01 00:00:00

abstract：:Highly active antiretroviral therapy rapidly reduces virus replication in the lymphoid tissue. Production of viral RNA, however, may still be detected in the lymphoid tissue despite negative plasma viremia. Continuing virus production and latent infection in resting cells seem to be important factors for viral rebound...

journal_title：Current opinion in infectious diseases

authors： Stellbrink HJ,van Lunzen J

更新日期：2001-02-01 00:00:00

abstract：:Interleukin-10 is the most potent anti-inflammatory cytokine yet identified. It has multiple actions affecting the innate immune system as well as humoral and cellular immune responses. It occupies a pivotal role in the regulation of the immune response to microbial pathogens in health and disease. Knowledge gained in...

journal_title：Current opinion in infectious diseases

authors： Opal SM,Huber CE

更新日期：2000-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Imiquimod is the first member of a new class of immune response modifiers; it was first approved in 1997 for the topical treatment of external genital and perianal warts. It is an imidazoquinoline, a novel synthetic compound which is an immune response stimulator, enhancing both the innate and acquire...

journal_title：Current opinion in infectious diseases

authors： Garland SM

更新日期：2003-04-01 00:00:00

abstract：PURPOSE OF REVIEW:A review of recent developments in the understanding of the natural history of anal squamous carcinoma arising from areas of high-grade anal intraepithelial neoplasia. RECENT FINDINGS:Anal intraepithelial neoplasia is a consequence of chronic human papillomavirus infection in the anal canal and appea...

journal_title：Current opinion in infectious diseases

authors： Fox PA

更新日期：2006-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Clostridioides difficile infection (CDI) is a significant burden on the health system, especially due to high recurrence rates. Since the beginning of the CDI epidemic in early 2000s, many strategies for combatting recurrence have been explored, with moderate success so far. This review will focus on ...

journal_title：Current opinion in infectious diseases

authors： Shin JH,Warren CA

更新日期：2019-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to summarize the emerging literature on nontuberculous mycobacteria outbreaks in healthcare settings. As our ability to identify mycobacterial species develops, we are better able to recognize epidemiologic connections and better understand the prevalence and importance o...

journal_title：Current opinion in infectious diseases

authors： Sood G,Parrish N

更新日期：2017-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Particularities of the fetal immune response to infection cause a heightened inflammatory state that acts synergistically with microbial insult to induce damage. Proteomics offers the opportunity for detecting fetuses at risk of sepsis and neurological injury. RECENT FINDINGS:Molecular tools (16S-rRN...

journal_title：Current opinion in infectious diseases

authors： Buhimschi CS,Bhandari V,Han YW,Dulay AT,Baumbusch MA,Madri JA,Buhimschi IA

更新日期：2009-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Nontuberculous mycobacterial disease, especially pulmonary disease, is increasingly encountered by clinicians. Therapy of the most common nontuberculous mycobacterial pathogen, Mycobacterium avium complex, improved with the introduction of macrolide-containing regimens, but treatment for this and most...

journal_title：Current opinion in infectious diseases

authors： Griffith DE

更新日期：2007-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Although available therapies can effectively inhibit hepatitis B virus (HBV) replication in patients with active chronic hepatitis B (CHB) infection, therapeutic efficacy is limited because of potential drug resistance, and an inability to mediate viral clearance and to rectify immune impairment in CH...

journal_title：Current opinion in infectious diseases

authors： Pan J,Tong S,Kang L,Tang J

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:We aim to review the epidemiology of respiratory viral infections and the strengths and limitations of multiplex respiratory pathogen panels that are currently available along with their respective features and differences. RECENT FINDINGS:We give particular emphasis to the pathogens included on each...

journal_title：Current opinion in infectious diseases

authors： Cawcutt KA,Fey PD,Kalil AC

更新日期：2017-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Toxoplasmosis in haematopoietic cell transplant (HCT) recipients is associated with high morbidity and mortality rates. Prophylaxis following HCT is recommended for high-risk pre-HCT toxoplasma-seropositive (pre-HCTSP) recipients. However, there is no agreement or consistency among programmes on wheth...

journal_title：Current opinion in infectious diseases

authors： Gajurel K,Dhakal R,Montoya JG

更新日期：2015-08-01 00:00:00

abstract：:The past few years have seen important developments in understanding the epidemiological and virological characteristics of rotaviruses, and rapid progress has been made in rotavirus vaccine development, but further challenges remain before a vaccine is introduced into widespread use. The licensure of the first rotavi...

journal_title：Current opinion in infectious diseases

authors： Lynch M,Bresee JS,Gentsch JR,Glass RI

更新日期：2000-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Bacillus Calmette-Guerin (BCG) vaccination has been performed since 1921, and remains the best method of preventing severe infections caused by Mycobacterium tuberculosis. Tuberculosis, in its various forms, remains a public health problem, and more than 100 countries continue BCG vaccination in an ef...

journal_title：Current opinion in infectious diseases

authors： Bellet JS,Prose NS

更新日期：2005-04-01 00:00:00

abstract：:Cystic fibrosis is the most common lethal inherited disorder with autosomal recessive inheritance. Major progress has been made in understanding the molecular mechanisms leading to increased susceptibility to Pseudomonas aeruginosa colonization. Persistent respiratory infection with P. aeruginosa leads to progressive ...

journal_title：Current opinion in infectious diseases

authors： Brennan AL,Geddes DM

更新日期：2002-04-01 00:00:00

abstract：PURPOSE OF REVIEW:In hematopoietic cell transplant (HCT) recipients, paramyxovirus infections are major viral respiratory tract infections that, if they progress to lower respiratory tract infections, are associated with reduced survival rates in this population. There are important knowledge gaps regarding treatment d...

journal_title：Current opinion in infectious diseases

authors： Batista MV,El Haddad L,Chemaly RF

更新日期：2018-12-01 00:00:00