Abstract:
:A systematic literature review was conducted to identify and summarize the clinical efficacy and safety of available antithrombotic therapies after peripheral endovascular or surgical revascularization in patients with peripheral artery disease (PAD). Five databases were searched using free-text and Emtree/Mesh terms for PAD, randomized controlled trials (RCTs), and antithrombotic therapies of interest (ie, single antiplatelet therapy, dual antiplatelet therapy, and vitamin K antagonists). Randomized controlled trials were eligible for inclusion if they assessed the risk of thrombotic events (ie, myocardial infarction, ischemic stroke, cardiovascular death, limb ischemia, or limb amputation) or safety profile (ie, minor, moderate, major, or fatal bleeding events) after revascularization. In total, 16 RCTs were identified. Only a few studies reported on treatment effects of the investigated therapies. Myocardial infarction, ischemic stroke, cardiovascular death, and amputation were reported in up to 2.3%, 2.3%, 5.6%, and 7.3% of patients, respectively. Bleeding events were observed in up to 8.4% (major) and 1.5% (fatal) of patients. Despite available treatments, patients with PAD undergoing revascularization remain at risk of thrombotic events. There is a need for new treatments that will help to optimize care for patients with symptomatic PAD undergoing revascularization.
journal_name
Angiologyjournal_title
Angiologyauthors
Schindewolf M,Beyer-Westendorf J,Balradj J,Bowrin K,Huelsebeck M,Briere JBdoi
10.1177/0003319720936505subject
Has Abstractpub_date
2020-10-01 00:00:00pages
773-790issue
9eissn
0003-3197issn
1940-1574journal_volume
71pub_type
杂志文章相关文献
ANGIOLOGY文献大全abstract::Vascular malformations of the mediastinum including mediastinal lymphangioma are exceedingly rare in adults. A resected case of mediastinal cystic lymphangioma (cystic hygroma) that presented with acute onset of retrosternal chest pain is reported in a 45-year-old man. Cystic hygromas are benign cysts frequently disco...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331970405500513
更新日期:2004-09-01 00:00:00
abstract::The authors encountered 2 brothers with hypertrophic cardiomyopathy (HCM), both of whom were later found to have progressed to dilated cardiomyopathy (DCM). Case No. 1 (younger brother): A diagnosis of HCM without left ventricular (LV) dilatation was made at age two by cardiac catheterization and echocardiogram. Howev...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979304400511
更新日期:1993-05-01 00:00:00
abstract::The relationship between echocardiographically measured epicardial fat thickness (EFT) and plasma concentrations of leptin, ghrelin, and adiponectin has not been evaluated in patients with noncachectic heart failure (HF). Patients with noncachectic HF and age- and sex-matched controls did not differ significantly in E...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319712447978
更新日期:2013-04-01 00:00:00
abstract::The changes in blood rheologic properties induced by exposure to high altitude plus heavy and prolonged physical strain were investigated in 14 climbers of an Italian expedition to Himalaya (maximum altitude reached m 7350). In blood samples collected immediately after return, alterations of some haemorheologic parame...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978403500708
更新日期:1984-07-01 00:00:00
abstract::Procoagulant and prothrombotic states in patients with chronic atrial fibrillation (AF) are higher than those in patients with normal sinus rhythm. We assessed and compared serum γ-glutamyltranferase (GGT) activity in elderly patients with nonvalvular AF and control participants with normal sinus rhythm. Consecutive p...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319712438956
更新日期:2013-02-01 00:00:00
abstract::To evaluate the aortic wall sclerosis in patients with coronary artery disease (CAD), the authors measured the aortic distensibility (AD) at the ascending and descending aorta by using cine magnetic resonance (MR). Cine MR was performed in 15 patients with CAD and 15 normal controls (NCs). Patients with CAD had angiog...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979604700206
更新日期:1996-02-01 00:00:00
abstract::The aim of this study was to analyze the left ventricular (LV) geometric changes occurring in chronic pressure overload due to valvular aortic stenosis (AS). Fifty-six adult patients (30 women, 26 men, mean age seventy-two +/- nine years, range forty-five to eighty-five years) with isolated AS (mean valve area by Dopp...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979404501206
更新日期:1994-12-01 00:00:00
abstract::Ostial left main coronary stenosis has a poor prognosis and increased mortality rate with coronary arteriography. Due to its anatomic location, visualization of the stenosis may be difficult. A high index of suspicion based upon only a few signs should prompt the physician to perform certain maneuvers to obtain the co...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978603700809
更新日期:1986-08-01 00:00:00
abstract::The authors evaluated the effects of verapamil (Ve) and magnesium sulfate (Mg) on the electrophysiologic changes induced in dogs during acute myocardial ischemia and following reperfusion. The effects of their intravenous (i.v.) administration and administration by coronary sinus retroperfusion (CSR) were also compare...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979604700604
更新日期:1996-06-01 00:00:00
abstract::The efficacy of physical training alone or combined with antiplatelet therapy (dipyridamole and aspirin) was studied in 30 patients with stage II peripheral arterial occlusive disease (PAOD). Patients were randomly allocated to one of the following groups: Group A--dipyridamole 75 mg three times daily and aspirin 330 ...
journal_title:Angiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/000331979104200701
更新日期:1991-07-01 00:00:00
abstract::Study on 295 consecutive medical patients to evaluate the potential of routine blood tests to identify the risk of deep vein thrombosis (DVT). The tests included in a DVT risk stratification model system were erythrocyte sedimentation rate, antithrombin III, C-reactive protein, D-dimer, and N-terminal pro-brain natriu...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319716673011
更新日期:2017-08-01 00:00:00
abstract::Because the literature comparing the effects of vasodilators on forearm and calf vessels is very scarce, the authors compared different vasodilators used in cardiovascular medicine in a group of volunteers. The peripheral effects were measured in the sitting position by plethysmography at the calf and at the forearm. ...
journal_title:Angiology
pub_type: 临床试验,杂志文章
doi:10.1177/000331979004100408
更新日期:1990-04-01 00:00:00
abstract::Although limb salvage rate has improved in critical limb ischemia (CLI), an improvement in CLI prognosis has been scarcely reported. Multidisciplinary therapy (MT) including revascularization, wound bed preparation, treatment of comorbidity, and education of patients with CLI may improve prognosis. The aim of this stu...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319714523113
更新日期:2015-02-01 00:00:00
abstract::The proportion of individuals >80 years of age constitute an increasing proportion of patients who present with ST-segment elevation myocardial infarction (STEMI). The objective of this study is to evaluate in-hospital outcomes and 1-year survival of very elderly patients who present with an STEMI and undergo primary ...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319717746520
更新日期:2018-09-01 00:00:00
abstract::We have previously developed a technique for the in vivo visualization of the pulmonary arteries in the experimental animal with a fiberoptic instrument (angioscope). To assess the potential hemodynamic and gas exchange effects of angioscopy, we studied five dogs before and after pulmonary embolization. Sequential obs...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978403500205
更新日期:1984-02-01 00:00:00
abstract::The cardiorenal anemia syndrome in congestive heart failure (CHF) is an independent risk factor for vascular morbidity and mortality. Several factors play a role in the pathogenesis of anemia in CHF, including inflammation, impaired renal function, use of certain antihypertensive or cardioprotective agents, and gastro...
journal_title:Angiology
pub_type: 杂志文章,评审
doi:10.1177/0003319708316169
更新日期:2009-02-01 00:00:00
abstract::The physiological basis of postischemic hyperemia is not yet fully understood. The present study investigated the effects of pharmacologic manipulation of the prostaglandin system on local hemodynamics. Strain-gauge plethysmography was used to study 8 normal subjects and 9 patients with obliterating arterial disease o...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979704800208
更新日期:1997-02-01 00:00:00
abstract::The functional capability of the deep femoral artery (DFA) as a collateral channel is an important feature in patients suffering peripheral arterial occlusive disease (PAOD). A noninvasive method of indirect quantification of the DFA blood flow volume is presented. In normal lower limbs, it was found that the common f...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978403500502
更新日期:1984-05-01 00:00:00
abstract::Lower mortality rates from coronary heart disease and higher levels of serum high-density lipoprotein cholesterol (HDL-C) have been observed in populations residing at high altitude. However, this effect has not been investigated in Arab populations, which exhibit considerable genetic homogeneity. We assessed the rela...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319714544355
更新日期:2015-07-01 00:00:00
abstract::A 78-year-old woman was admitted for pulmonary embolism requiring orotracheal intubation and positive end-expiratory pressure. The pulmonary angiography confirmed a massive pulmonary embolism as suggested by echocardiography. Heparin and recombinant tissue plasminogen activator were successfully administrated; neverth...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331970405500411
更新日期:2004-07-01 00:00:00
abstract::A 25-year-old man with low cardiac risks underwent coronary arteriography because of chest pain at rest. His only risk factors for coronary artery disease was smoking. Both right and left coronary arteries were ectatic and the left anterior descending artery was obstructed. In the acetylcholine provocation test, the l...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331970005100911
更新日期:2000-09-01 00:00:00
abstract::This report describes a case of aneurysm of the ascending aorta with secondary, severe, aortic valve incompetence following temporal arteritis in a sixty-five-year-old woman. ...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978703800909
更新日期:1987-09-01 00:00:00
abstract::The authors report a rare case of congenital Budd-Chiari syndrome in a twenty-eight-year-old male mongoloid. The patient was submitted to azygous-portal disconnection, because of the syndrome of portal hypertension supposedly due to cirrhosis of the liver. He died of hemorrhage of the liver on the third postoperative ...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978803900211
更新日期:1988-02-01 00:00:00
abstract::A 13-year-old girl was successfully recuperated from cardiopulmonary arrest shortly after running 80 m in a competition. The electrocardiogram, echocardiogram and 123I-MIBG myocardial scintigraphic imaging indicated myocardial ischemia in the anteroseptal wall of the left ventricle. Coronary angiography during the rec...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331970305400214
更新日期:2003-03-01 00:00:00
abstract::The long-term outcome of primary successful percutaneous transluminal angioplasty (PTA) for patients with peripheral occlusive arterial disease (POAD) is frequently compromised by the development of restenosis, especially when extensive dissections result from the angioplastic procedure. Unfortunately, prevention of t...
journal_title:Angiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/000331970105201002
更新日期:2001-10-01 00:00:00
abstract:PURPOSE:Revascularizing procedures like percutaneous transluminal coronary angioplasty (PTCA) aim at reducing the incidence and severity of myocardial ischemia. To evaluate this, continuous Holter ST analysis is a possible method. DESIGN:41 patients (35 men, 6 women) with stable angina pectoris had continuous twenty-f...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979104200601
更新日期:1991-06-01 00:00:00
abstract::This study investigated the feasibility of four-dimensional electrocardiography (4-D ECG), a new display in which the vector loop was rotated and scanned along a timed axis to overcome the shortcomings of vectorcardiography (VCG). The subjects consisted of 38 patients with premature atrial complexes and 30 controls. T...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979604701111
更新日期:1996-11-01 00:00:00
abstract::Obesity is new in human evolutionary history, having become possible at the population level with increased food security. As with any phenotype, obesity is at base an outcome of gene-environment interactions. However, different disciplines working in obesity research have identified different facets of the problem an...
journal_title:Angiology
pub_type: 杂志文章,评审
doi:10.1177/0003319708320763
更新日期:2008-04-01 00:00:00
abstract::Spontaneous coronary artery dissection is a rare event and only in a few patients has the diagnosis been angiographically confirmed during life. A spontaneous dissection of the right coronary artery was detected as a cause of out-of-hospital cardiac arrest in a patient with coronary artery ectasia. ...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979104200210
更新日期:1991-02-01 00:00:00
abstract:PURPOSE:To evaluate the prevalence of significant coronary artery disease (CAD) and nondiagnostic studies in patients referred for clinically indicated coronary angiography performed by 128 multidetector computed tomography (MDCT). METHODS:We examined patients referred for coronary computed tomography (CT) angiography...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319709335513
更新日期:2010-02-01 00:00:00