当前位置： SCI文献检索 > EUROPEAN RADIOLOGY期刊下所有文献 > A deep learning approach to characterize 2019 coronavirus disease (COVID-19) pneumonia in chest CT images.

A deep learning approach to characterize 2019 coronavirus disease (COVID-19) pneumonia in chest CT images.

Abstract：

OBJECTIVES:To utilize a deep learning model for automatic detection of abnormalities in chest CT images from COVID-19 patients and compare its quantitative determination performance with radiological residents. METHODS:A deep learning algorithm consisted of lesion detection, segmentation, and location was trained and validated in 14,435 participants with chest CT images and definite pathogen diagnosis. The algorithm was tested in a non-overlapping dataset of 96 confirmed COVID-19 patients in three hospitals across China during the outbreak. Quantitative detection performance of the model was compared with three radiological residents with two experienced radiologists' reading reports as reference standard by assessing the accuracy, sensitivity, specificity, and F1 score. RESULTS:Of 96 patients, 88 had pneumonia lesions on CT images and 8 had no abnormities on CT images. For per-patient basis, the algorithm showed superior sensitivity of 1.00 (95% confidence interval (CI) 0.95, 1.00) and F1 score of 0.97 in detecting lesions from CT images of COVID-19 pneumonia patients. While for per-lung lobe basis, the algorithm achieved a sensitivity of 0.96 (95% CI 0.94, 0.98) and a slightly inferior F1 score of 0.86. The median volume of lesions calculated by algorithm was 40.10 cm3. An average running speed of 20.3 s ± 5.8 per case demonstrated the algorithm was much faster than the residents in assessing CT images (all p < 0.017). The deep learning algorithm can also assist radiologists make quicker diagnosis (all p < 0.0001) with superior diagnostic performance. CONCLUSIONS:The algorithm showed excellent performance in detecting COVID-19 pneumonia on chest CT images compared with resident radiologists. KEY POINTS:• The higher sensitivity of deep learning model in detecting COVID-19 pneumonia were found compared with radiological residents on a per-lobe and per-patient basis. • The deep learning model improves diagnosis efficiency by shortening processing time. • The deep learning model can automatically calculate the volume of the lesions and whole lung.

journal_name

Eur Radiol

journal_title

European radiology

authors

Ni Q,Sun ZY,Qi L,Chen W,Yang Y,Wang L,Zhang X,Yang L,Fang Y,Xing Z,Zhou Z,Yu Y,Lu GM,Zhang LJ

doi

10.1007/s00330-020-07044-9

subject

Has Abstract

pub_date

2020-12-01 00:00:00

pages

6517-6527

issue

eissn

0938-7994

issn

1432-1084

pii

10.1007/s00330-020-07044-9

journal_volume

pub_type

杂志文章,多中心研究

在线工具

A deep learning approach to characterize 2019 coronavirus disease (COVID-19) pneumonia in chest CT images.