Force fluctuation on pulling a ssDNA from a carbon nanotube.

abstract：:This study presents a method for estimating the spatial variations in material properties of elastic membranes, such as biological tissue, which contain both inhomogeneous strain fields and inhomogeneous material properties. In order to validate the method, an inhomogeneous, isotropic rubber membrane was biaxially loa...

journal_title：Biomechanics and modeling in mechanobiology

authors： Nielsen PM,Malcolm DT,Hunter PJ,Charette PG

更新日期：2002-12-01 00:00:00

abstract：:The level of hematocrit (Hct) is known to affect mean arterial pressure (MAP) by influencing blood viscosity. In the healthy population, an increase in Hct (and corresponding increase in viscosity) tends to raise MAP. However, data from a clinical study of type 2 diabetic patients indicate that this relationship is no...

journal_title：Biomechanics and modeling in mechanobiology

authors： Branigan T,Bolster D,Vázquez BY,Intaglietta M,Tartakovsky DM

更新日期：2011-07-01 00:00:00

abstract：:The diseases of human blood vessels are closely associated with local mechanical variations. A better understanding of the quantitative correlation in mechanical environment between the current mechano-biological studies and vascular physiological or pathological conditions in vivo is crucial for evaluating numerous e...

journal_title：Biomechanics and modeling in mechanobiology

authors： Yang S,Gong X,Qi Y,Jiang Z

更新日期：2020-04-01 00:00:00

abstract：:Flow-induced damage to red blood cells has been an issue of considerable importance since the introduction of the first cardiovascular devices. Early blood damage prediction models were based on measurements of damage by shear stress only. Subsequently, these models were extrapolated to include other components of the...

journal_title：Biomechanics and modeling in mechanobiology

authors： Faghih MM,Sharp MK

更新日期：2020-02-01 00:00:00

abstract：:Adherent cells sense their mechanical environment, which, in turn, regulates their functions. During the past decade, a growing body of evidence has indicated that a deformable, solid-state intracellular structure known as the cytoskeleton (CSK) plays a major role in transmitting and distributing mechanical stresses w...

journal_title：Biomechanics and modeling in mechanobiology

authors： Stamenović D,Ingber DE

更新日期：2002-06-01 00:00:00

abstract：:In adaptive bone remodeling, mechanical signals such as stress/strain caused by loading/deformation are believed to play important roles as regulators of the process in which osteoclastic resorption and osteoblastic formation are coordinated under a local mechanical environment. The mechanism by which cells sense and ...

journal_title：Biomechanics and modeling in mechanobiology

authors： Adachi T,Sato K,Tomita Y

更新日期：2003-11-01 00:00:00

abstract：:It is believed that non-mammals have poor hearing at high frequencies because the sound-conduction performance of their single-ossicle middle ears declines above a certain frequency. To better understand this behavior, a dynamic three-dimensional finite-element model of the chicken middle ear was constructed. The effe...

journal_title：Biomechanics and modeling in mechanobiology

authors： Muyshondt PGG,Dirckx JJJ

更新日期：2020-02-01 00:00:00

abstract：:It has been demonstrated that interstitial fluid (IF) flow can play a crucial role in tumor cell progression. Swartz and collaborators (Cancer Cell 11: 526-538, Shields et al. 2007) demonstrated that cells that secrete the lymphoid homing chemokines CCL21/CCL19 and express their receptor CCR7 could use flow to bias th...

journal_title：Biomechanics and modeling in mechanobiology

authors： Urdal J,Waldeland JO,Evje S

更新日期：2019-08-01 00:00:00

abstract：:Micro-indentation is a new experimental approach to assess physical cellular properties. Here we attempt to quantify the contribution of geometrical parameters to a cylindrical plant cell's resistance to lateral deformation. This information is important to correctly interpret data obtained from experiments using the ...

journal_title：Biomechanics and modeling in mechanobiology

authors： Bolduc JE,Lewis LJ,Aubin CE,Geitmann A

更新日期：2006-11-01 00:00:00

abstract：:We propose a mechanical model of generation of vitreoretinal tractions in the presence of posterior vitreous detachment (PVD). PVD is a common occurrence with aging, and it consists in the separation of the vitreous body from the retina at the back pole of the eye, due to progressive shrinking of the vitreous gel. Dur...

journal_title：Biomechanics and modeling in mechanobiology

authors： Di Michele F,Tatone A,Romano MR,Repetto R

更新日期：2020-12-01 00:00:00

abstract：:Medical studies have consistently shown that the best defense against cancer is early detection. Due to this, many efforts have been made to develop methods of screening patient blood quickly and cheaply. These methods range from separation via differences in size, electrostatic potential, chemical potential, antibody...

journal_title：Biomechanics and modeling in mechanobiology

authors： Becton M,Averett RD,Wang X

更新日期：2019-04-01 00:00:00

abstract：:Mechanical cues that trigger pathological remodeling in smooth muscle tissues remain largely unknown and are thought to be pivotal triggers for strain-induced remodeling. Thus, an understanding of the effects mechanical stimulation is important to elucidate underlying mechanisms of disease states and in the developmen...

journal_title：Biomechanics and modeling in mechanobiology

authors： Heise RL,Parekh A,Joyce EM,Chancellor MB,Sacks MS

更新日期：2012-01-01 00:00:00

abstract：:In this study, we hypothesized that spatial relationships exist between the local mechanical environment and inflammatory marker expression in atherosclerotic plaques, and that these relationships are plaque-progression dependent. Histologic cross-sections were collected at regular intervals along the length of diseas...

journal_title：Biomechanics and modeling in mechanobiology

authors： Hallow KM,Taylor WR,Rachev A,Vito RP

更新日期：2009-12-01 00:00:00

abstract：:As a degenerative and inflammatory desease of elderly patients, about 80% of abdominal aortic aneurysms (AAA) show considerable wall calcification. Effect of calcifications on computational wall stress analyses of AAAs has been rarely treated in literature so far. Calcifications are heterogeneously distributed, non-fi...

journal_title：Biomechanics and modeling in mechanobiology

authors： Maier A,Gee MW,Reeps C,Eckstein HH,Wall WA

更新日期：2010-10-01 00:00:00

abstract：:We use supersonic shear wave imaging (SSI) technique to measure not only the linear but also the nonlinear elastic properties of brain matter. Here, we tested six porcine brains ex vivo and measured the velocities of the plane shear waves induced by acoustic radiation force at different states of pre-deformation when ...

journal_title：Biomechanics and modeling in mechanobiology

authors： Jiang Y,Li G,Qian LX,Liang S,Destrade M,Cao Y

更新日期：2015-10-01 00:00:00

abstract：:Knowledge of the complete three-dimensional (3D) mechanical behavior of soft tissues is essential in understanding their pathophysiology and in developing novel therapies. Despite significant progress made in experimentation and modeling, a complete approach for the full characterization of soft tissue 3D behavior rem...

journal_title：Biomechanics and modeling in mechanobiology

authors： Avazmohammadi R,Li DS,Leahy T,Shih E,Soares JS,Gorman JH,Gorman RC,Sacks MS

更新日期：2018-02-01 00:00:00

abstract：:Lattice Boltzmann models (LBM) are rapidly showing their ability to simulate a lot of fluid dynamics problems that previously required very complex approaches. This study presents a LBM for simulating diffusion-advection transport of substrate in a 2-D laminar flow. The model considers the substrate influx into a set ...

journal_title：Biomechanics and modeling in mechanobiology

authors： Moaty Sayed AA,Hussein MA,Becker T

更新日期：2010-04-01 00:00:00

abstract：:In its permanent quest of mechanobiological homeostasis, our vasculature significantly adapts across multiple length and timescales in various physiological and pathological conditions. Computational modeling of vascular growth and remodeling (G&R) has significantly improved our insights into the mechanobiological pro...

journal_title：Biomechanics and modeling in mechanobiology

authors： Mousavi SJ,Farzaneh S,Avril S

更新日期：2019-12-01 00:00:00

abstract：:Aortic valve (AV) calcification is a highly prevalent disease with serious impact on mortality and morbidity. The exact causes and mechanisms of AV calcification are unclear, although previous studies suggest that mechanical forces play a role. It has been clinically demonstrated that calcification preferentially occu...

journal_title：Biomechanics and modeling in mechanobiology

authors： Yap CH,Saikrishnan N,Yoganathan AP

更新日期：2012-01-01 00:00:00

abstract：:Locust wings are able to sustain millions of cycles of mechanical loading during the lifetime of the insect. Previous studies have shown that cross veins play an important role in delaying crack propagation in the wings. Do cross veins thus also influence the fatigue behaviour of the wings? Since many important fatigu...

journal_title：Biomechanics and modeling in mechanobiology

authors： Rajabi H,Bazargan P,Pourbabaei A,Eshghi S,Darvizeh A,Gorb SN,Taylor D,Dirks JH

更新日期：2017-12-01 00:00:00

abstract：:Articular cartilage is a complex, anisotropic, stratified tissue with remarkable resilience and mechanical properties. It has been subject to extensive modelling as a multiphase medium, with many recent studies examining the impact of increasing detail in the representation of this tissue's fine scale structure. Howev...

journal_title：Biomechanics and modeling in mechanobiology

authors： Klika V,Whiteley JP,Brown CP,Gaffney EA

更新日期：2019-08-01 00:00:00

abstract：:The controlled cortical impact (CCI) model is widely used in many laboratories to study traumatic brain injury (TBI). Although external impact parameters during CCI tests could be clearly defined, little is known about the internal tissue-level mechanical responses of the rat brain. Furthermore, the external impact pa...

journal_title：Biomechanics and modeling in mechanobiology

authors： Mao H,Yang KH,King AI,Yang K

更新日期：2010-12-01 00:00:00

abstract：:Determining the biomechanical behavior of heart valve leaflet tissues in a noninvasive manner remains an important clinical goal. While advances in 3D imaging modalities have made in vivo valve geometric data available, optimal methods to exploit such information in order to obtain functional information remain to be ...

journal_title：Biomechanics and modeling in mechanobiology

authors： Aggarwal A,Sacks MS

更新日期：2016-08-01 00:00:00

abstract：:The mechanotransduction of adipocytes is not well characterized in the literature. In this study, we employ stochastic modeling fitted to experiments for characterizing the influence of mechanical stretching delivered to adipocyte monolayers on the probabilities of commitment to the adipocyte lineage, mitosis, and gro...

journal_title：Biomechanics and modeling in mechanobiology

authors： Shoham N,Gefen A

更新日期：2012-09-01 00:00:00

abstract：:Articular cartilage is a multicomponent, poroviscoelastic tissue with nonlinear mechanical properties vital to its function. A consequent goal of repair or replacement of injured cartilage is to achieve mechanical properties in the repair tissue similar to healthy native cartilage. Since fresh healthy human articular ...

journal_title：Biomechanics and modeling in mechanobiology

authors： Ronken S,Arnold MP,Ardura García H,Jeger A,Daniels AU,Wirz D

更新日期：2012-05-01 00:00:00

abstract：:The first carpometacarpal (CMC) joint, located at the base of the thumb and formed by the junction between the first metacarpal and trapezium, is a common site for osteoarthritis of the hand. The shape of both the first metacarpal and trapezium contributes to the intrinsic bony stability of the joint, and variability ...

journal_title：Biomechanics and modeling in mechanobiology

authors： Rusli WMR,Kedgley AE

更新日期：2020-08-01 00:00:00

abstract：:Ischemic stroke is a major cause of death and long-term disabilities worldwide. In this paper, we aim to represent a comprehensive simulation of the motion of emboli through cerebrovascular network within patient-specific computational model. The model consists of major arteries of the circle of Willis reconstructed f...

journal_title：Biomechanics and modeling in mechanobiology

authors： Khodaee F,Vahidi B,Fatouraee N

更新日期：2016-10-01 00:00:00

abstract：:The present study examines the possibility of attenuating blood pulses by means of introducing prosthetic viscoelastic materials able to absorb energy and damp such pulses. Vascular prostheses made of polymeric materials modify the mechanical properties of blood vessels. The effect of these materials on the blood puls...

journal_title：Biomechanics and modeling in mechanobiology

authors： Menacho J,Rotllant L,Molins JJ,Reyes G,García-Granada AA,Balcells M,Martorell J

更新日期：2018-04-01 00:00:00

abstract：:Skin expansion delivers newly grown skin that maintains histological and mechanical features of the original tissue. Although it is the gold standard for cutaneous defect correction today, the underlying mechanisms remain poorly understood. Here we present a novel technique to quantify anisotropic prestrain, deformati...

journal_title：Biomechanics and modeling in mechanobiology

authors： Buganza Tepole A,Gart M,Purnell CA,Gosain AK,Kuhl E

更新日期：2015-10-01 00:00:00

abstract：:Ventricular growth is widely considered to be an important feature in the adverse progression of heart diseases, whereas reverse ventricular growth (or reverse remodeling) is often considered to be a favorable response to clinical intervention. In recent years, a number of theoretical models have been proposed to mode...

journal_title：Biomechanics and modeling in mechanobiology

authors： Lee LC,Genet M,Acevedo-Bolton G,Ordovas K,Guccione JM,Kuhl E

更新日期：2015-04-01 00:00:00