[Visual acuity following Descemet-membrane endothelial keratoplasty (DMEK): first 100 cases operated on for Fuchs endothelial dystrophy].

Abstract:

PURPOSE:The aim of this study was to evaluate the visual outcome and endothelial cell density in the first series of 100 eyes after Descemet membrane endothelial keratoplasty (DMEK) for the treatment of Fuchs endothelial dystrophy. DESIGN:This was a non-randomised prospective clinical trial. METHODS:The first 100 consecutive eyes (87 patients) that underwent DMEK (i. e., transplantation of an isolated donor Descemet membrane carrying its endothelium) for Fuchs endothelial dystrophy were evaluated. In all eyes, the best corrected visual acuity (BCVA) as well as the endothelial cell density (ECD) were measured before and at one, three and six months after surgery. RESULTS:In eyes with a functional DMEK graft and good visual potential (n = 78), the BCVA was > or = 20 / 40 (> or = 0.5) in 79 % after 1 month, 94 % after 3 months, and 96 % after six months; > or = 20 / 25 (> or = 0.8) in respectively 54 %, 64 %, and 74 %, and > or = 20 / 20 (> or = 1.0) in respectively 26 %, 36 %, and 45 %. In this group, ECD averaged 2630 (+/- 190) cells/mm (2) before, and 1800 (+/- 540) cells/mm (2) at six months after surgery (n = 76). In 15 eyes, a secondary "Descemet stripping endothelial keratoplasty" (DSEK) was performed. When the outcomes of DMEK and secondary DSEK procedures were combined, 91 % reached a BCVA of > or = 20 / 40 (> or = 0.5), 65 % > or = 20 / 25 (> or = 0.8) and 38 % > or = 20 / 25 (> or = 1.0) at six months after surgery (n = 93). For the whole group, ECD averaged 2620 (+/- 190) cells/mm (2) before, and 1730 (+/- 590) cells/mm (2) at six months after surgery (n = 89). CONCLUSION:DMEK may provide relatively quick and nearly complete visual rehabilitation in a majority of patients operated on for Fuchs endothelial dystrophy. Endothelial cell survival may be similar to earlier types of endothelial keratoplasty. Early graft detachment (19 cases) was the main complication in this first series of DMEK surgeries.

journal_name

Klin Monbl Augenheilkd

authors

Droutsas K,Ham L,Dapena I,Geerling G,Oellerich S,Melles G

doi

10.1055/s-0029-1245446

subject

Has Abstract

pub_date

2010-06-01 00:00:00

pages

467-77

issue

6

eissn

0023-2165

issn

1439-3999

journal_volume

227

pub_type

临床试验,杂志文章
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    pub_type: 杂志文章

    doi:10.1055/s-2008-1054851

    authors: Fuhrmeister H

    更新日期:1983-06-01 00:00:00

  • [A training device for intraocular surgery (author's transl)].

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    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Spitznas M

    更新日期:1976-03-01 00:00:00

  • [Dynamic Contour Tonometry and Goldmann Applanation Tonometry: Difference of Intraocular Pressure Values Between Eyes with and without Glaucomatous Damage in Thin Corneas].

    abstract:BACKGROUND:To examine the differences in intraocular pressure (IOP) measurements obtained with Goldmann applanation tonometry (GAT) and Pascal dynamic contour tonometry (DCT) in subjects with thin corneas and to correlate these with structural and functional parameters of glaucoma damage. PATIENTS AND METHODS:One hund...

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    authors: Umurhan Akkan JC,Akkan F,Sezgin Akcay BI,Ayintap E,Tuncer K

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  • [Blepharospasm treatment with botulinum toxin (follow-up)].

    abstract::Within a period of 14 months 73 patients with idiopathic blepharospasm which could not be treated satisfactorily by any other form of therapy were treated by injections of botulin toxin. In 55 cases the follow-up period was sufficiently long to permit an evaluation. Thirty-five patients were temporarily completely fre...

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    doi:10.1055/s-2008-1050804

    authors: Roggenkämper P

    更新日期:1986-10-01 00:00:00

  • [Glaucoma screening by means of pupil campimetry].

    abstract:BACKGROUND:The aim of the study was to find out if pupillographic assessment of the visual field by means of pupil campimetry can identify glaucomatous visual field defects and as such be used for glaucoma screening purposes. PATIENTS AND METHODS:20 patients with open angle glaucoma and 30 healthy persons were examine...

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    doi:10.1055/s-0032-1314985

    authors: Skorkovská K,Kelbsch C,Blumenstock G,Wilhelm H,Wilhelm B

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  • [Optimization of irradiation time in the treatment of malignant melanoma of the choroid with beta applicators (106Ru/106Rh)].

    abstract::Brachytherapy with 106Ru/106Rh necessitates protracted irradiation because the applicators have to be sutured to the sclera. Protracted radiotherapy causes more intensive damage in tumor cells with increased metabolism and a higher mitosis rate than in normal tissue. Beta irradiation of rabbit eyes with 0.258-0.231 Gy...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

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    doi:10.1055/s-2008-1050770

    authors: Lommatzsch PK,Weise B,Ballin R

    更新日期:1986-08-01 00:00:00

  • [Experimental venous thrombosis: preretinal PO2 before and after photocoagulation].

    abstract::Experimental occlusion of a retinal vein leads to retinopathy in the affected drainage area. In some cases the formation of ischemic regions, where the retina is completely destroyed, is typical for the development of this retinopathy. Laser photocoagulation restores the physiological preretinal oxygen pressure in the...

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    doi:10.1055/s-2008-1050970

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    更新日期:1985-06-01 00:00:00

  • [Fungal growth on soft contact lenses (author's transl)].

    abstract::The relevance of fungal contamination of soft contact lenses is demonstrated by own clinical observations in 25 cases. It can be shown by surface-microscopical, histological and mycological analysis, that various fungi can not only grow on the surface of HEMA-lenses, but can also invade the material. The efficacy of c...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Neuhann T,Blassmann K,Roth HW

    更新日期:1978-11-01 00:00:00

  • [Possibilities of microsurgery on ophthalmic vessels (author's transl)].

    abstract::Ciliary arteries, isolated from the eyes of human cadavers, were incised or severed under the microscope in order to test the technical possibilities of placing sutures or creating leak-proof anastomoses in ophthalmic vessels. Commercially available, minute atraumatic needles and 10-0 "Ethilon" or 15-0 Supramid suture...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

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    doi:10.1055/s-2008-1057589

    authors: Gundorowa RA,Galtschin AS

    更新日期:1980-06-01 00:00:00

  • [Modified moisture chamber].

    abstract:BACKGROUND:Moisture chambers can protect the eye in corneal lubrication or eyelid closure disorders. However, in cases with protrusio bulbi or pronounced chemosis conjunctivae direct damaging contact of the cornea or conjunctiva on the one hand and the inside of the moisture-chamber-bandage on the other hand are possib...

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    pub_type: 杂志文章

    doi:10.1055/s-2008-1034745

    authors: Winter M,Kandzia C

    更新日期:1999-01-01 00:00:00

  • [Analysis of Factors Influencing the Suitability of Donor Corneas in the LIONS Cornea Bank Saar-Lor-Lux, Trier/Westpfalz from 2006 to 2016].

    abstract:BACKGROUND AND PURPOSE:With the discrepancy between availability and demand for corneal donors, the purpose of our study was to identify significant factors influencing the suitability and affecting the main reasons for discarding organ-cultured corneas. We thus aimed to minimise the percentage of unsuitable corneas in...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

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    authors: Kramp K,Suffo S,Laun D,Bischoff-Jung M,Huber M,Langenbucher A,Seitz B

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  • [Keratitis in measles].

    abstract::We are reporting a case of a 23-year-old patient suffering from measles despite vaccination during childhood. He presented with bilateral punctate keratitis without conjunctival reaction 10 days after the onset of rash. We assume a late immunological reaction, possibly related to earlier vaccination. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1035466

    authors: Trüb PR

    更新日期:1995-05-01 00:00:00

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    doi:10.1055/s-2008-1057620

    authors: Lepper RD,Trier HG,Reuter R

    更新日期:1980-07-01 00:00:00

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    authors: Pau H

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  • [Anti VEGF Therapy Under Real-Life Conditions: Adherance Determines Long Term Outcome in Neovascular AMD].

    abstract:BACKGROUND:Data from real-life studies on neovascular AMD (nvAMD) generally fall significantly behind respective data from interventional prospective trials. This can be attributed at least partially to differences in patient cohorts concerning both stages of AMD (including consecutive scarring or atrophy), as well as ...

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    authors: Sachs HG,Wilke RG

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  • Inter-Rater Reliability of Cyclotorsion Measurements Using Fundus Photography.

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    pub_type: 杂志文章

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    authors: Dysli M,Kanku M,Traber GL

    更新日期:2018-04-01 00:00:00

  • [Occurrence of diffusions shown by fluorescence angiography of the laser coagulation in animals (author's transl)].

    abstract::Laser treated rat fundi were observed angiographically and with the fluorescence microscope for 3 months. Angiographically diffusions have been observable up to about one week post laser, fluorescence microscopically, however, for the whole observation time of 3 months. From the 2nd week, these diffusions were produce...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Baurmann H,Chioralia G,Schomacher L,Sasaki K

    更新日期:1976-04-01 00:00:00

  • [Liquid perfluorocarbon in treatment of giant tears].

    abstract::In 20 cases of giant tears with considerable proliferative changes, vitreoretinal silicone-oil-surgery was performed. With liquid perfluorocarbon, the involuted retina could easily be fixed during the operation in its former position without difficulties, before silicone oil as a permanent tamponade was used. The good...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

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    doi:10.1055/s-2008-1046078

    authors: Le Mer Y,Kroll P

    更新日期:1991-10-01 00:00:00

  • [Notes on a modification of Cüpper's Faden operation (the "false faden") (author's transl)].

    abstract::A "false faden operation was performed in 13 cases. In contrast to Cüpper's faden operation it had no lasting effect. The results of other authors were not confirmed. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Kaufmann H

    更新日期:1981-03-01 00:00:00

  • [The Fieldmaster-200 computer perimeter: a comparative, controlled clinical study of its sensitivity and specificity in glaucomatous field defects (author's transl)].

    abstract::The central visual fields of 119 glaucomatous eyes (78 patients) were evaluated under controlled conditions using the Goldmann kinetic perimeter and the Fieldmaster-200 automatic supra-threshold computer perimeter. Where there were qualitative differences between the two instruments, the high-resolution program 61 of ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-2008-1057325

    authors: Krieglstein GK,Glaab E,Gramer E

    更新日期:1981-11-01 00:00:00

  • [Disorders of binocular vision in amblyopic patients working at computer terminals].

    abstract::For the first time two cases are described with disturbances of binocular vision caused by subjective perception of positive scotomata in the amblyopic eye. The visual strain of working at a terminal leads to a slight increase in the squint angle; as a result, a paracentral scotoma may shift into the middle of the bin...

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    pub_type: 杂志文章

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    authors: Stangler-Zuschrott E,Harrer S

    更新日期:1985-11-01 00:00:00

  • [Ocular Manifestation of Mucopolysaccharidosis I-S (Scheie's Syndrome)].

    abstract:BACKGROUND:Bilateral stromal corneal opacifications are a differential diagnostical challenge to identify associated systemic diseases. CASE-REPORT:A 47-year old civil engineer (height 167 cm) with bilateral stromal corneal clouding presented with visual loss for the last 27 years: VA 20/100 OD and 20/50 OS (following...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2002-35688

    authors: Viestenz A,Shin YS,Viestenz A,Naumann GO

    更新日期:2002-10-01 00:00:00

  • [Optic Disk Drusen: Historical and Up-To-Date Aspects].

    abstract::Optic disc drusen are an important differential diagnosis in the diagnostic evaluation of a prominent optic nerve head. Drusen of the optic disc occur in 0.34 to 2.4 % of human individuals and manifest themselves bilaterally in three of four cases. Drusen are found six times more often within histological sections tha...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-0042-101554

    authors: Nentwich MM,Maertz J,Rudolph G

    更新日期:2016-03-01 00:00:00

  • [A contribution to the management of paracentral retinal branch vein obstruction (author's transl)].

    abstract::11 eyes (11 patients) with cystoid macular edema secondary to central retinal branch vein occlusion were treated with Laser-coagulations. In 11 eyes macular edema disappeared completely. In 10 eyes visual acuity improved during the next months. One eye developed a macular hole with decrease of visual acuity. The resul...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Paulmann H

    更新日期:1976-04-01 00:00:00

  • [Empty sella turcica and papilloedema (author's transl)].

    abstract::In a 49-year-old patient bilateral papilloedema with an empty sella turcica was observed. A summary of the literature references to this syndrome and its pathogenesis and its eye complications are given and discussed. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Szécsi K

    更新日期:1978-04-01 00:00:00

  • [Intraocular solitary granuloma of toxocara canis (author's transl)].

    abstract::5 cases of intraocular Toxocara canis solitary granuloma are demonstrated. The coincidence of two different aspects of a disease: pseudocoloboma of the macula (toxoplasmosis) in the right and a toxocara solitary granuloma in the left eye of the same patient (case 5) perhaps will furnish proof possibility of foetal inf...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Huismans H

    更新日期:1976-08-01 00:00:00

  • [The frequency of various forms of senile cataract (author's transl)].

    abstract::On classifying 1000 senile cataracts it was found that in pure cataract forms - starting from the cortex - the typical grey senile cataract (cataracta supranuclearis) mostly occurs with a clear nucleus. The dense permeability cataract (cataracta subcapsularis) most frequently shows a dense grey clouding of the nucleus...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Pau H

    更新日期:1976-08-01 00:00:00

  • [Pharmacotherapy of Non-neovascular AMD].

    abstract:BACKGROUND:Non-neovascular age-related macular degeneration (AMD) is not yet treatable. This article summarises current clinical research approaches. The reasons for the current lack of success are analysed. METHODS:Literature and databank search. RESULTS:The number of therapeutic approaches and mechanisms is limited...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/a-0914-3183

    authors: Zeitz O,Frentzel DP,Rübsam A,Seibel I,Riechardt AI,Brockmann C,Meißner F,Joussen AM

    更新日期:2019-09-01 00:00:00

  • [Surgery of strabismus and rupture of the blood-aqueous barrier (ischemia of the anterior segment)].

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    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1034887

    authors: Sanchez E,Klainguti G,Herbort CP

    更新日期:1998-05-01 00:00:00

  • [Landolt C and snellen e acuity: differences in strabismus amblyopia?].

    abstract:BACKGROUND:Assessment of visual acuity depends on the optotypes used for measurement. The ability to recognize different optotypes differs even if their critical details appear under the same visual angle. Since optotypes are evaluated on individuals with good visual acuity and without eye disorders, differences in the...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2005-858613

    authors: Becker R,Gräf M

    更新日期:2006-01-01 00:00:00