The synthesis of androstane brassinosteroid analogues with alpha-azido acid ester groups in position 17beta.

Abstract:

:Androstane brassinosteroid analogues with alpha-azido acid ester groups in position 17beta were synthesized from 2alpha,3alpha,17beta-trihydroxy-5alpha-androstan-6-one after the protection of the 2alpha,3alpha-diols upon treatment with the corresponding alpha-azido acid and the subsequent deprotection of the diol grouping. Six new castasterone analogues were prepared. The biological activities were evaluated in two bioassays: a rice lamina inclination test and bean second internode bioassays. The activities of the new analogues differ in these two bioassays.

journal_name

Steroids

journal_title

Steroids

authors

Hnilickova J,Kohout L,Capdevila E,Esteve A,Vilaplana M,Molist M,Brosa C,Swaczynova-Oklestkova J,Slavikova B

doi

10.1016/j.steroids.2010.06.012

subject

Has Abstract

pub_date

2010-12-01 00:00:00

pages

1005-10

issue

12

eissn

0039-128X

issn

1878-5867

pii

S0039-128X(10)00175-3

journal_volume

75

pub_type

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