Treatment outcome in a cohort of young patients with polycythemia vera.

abstract：:The idea of using small RNA fragments (oligonucleotides) for therapeutic purposes dates back to the 1990s, following the landmark discoveries on the mechanisms of gene silencing and RNA-interference (RNA-i). However, the first applications in medicine were hampered by difficulties in chemical stabilization and efficie...

journal_title：Internal and emergency medicine

authors： Girelli D,Busti F,Marchi G,Martinelli N,Olivieri O

更新日期：2018-04-01 00:00:00

abstract：:Nowadays, amiodarone is the most commonly used antidysrhythmic drug in clinical practice. It is highly effective in the management of recurrent ventricular dysrhythmias, paroxysmal supraventricular dysrhythmias, including atrial fibrillation and flutter, and in the maintenance of sinus rhythm after electrical cardiove...

journal_title：Internal and emergency medicine

authors： Hudzik B,Zubelewicz-Szkodzinska B

更新日期：2014-12-01 00:00:00

abstract：:Rapid diagnostic tools for Helicobacter pylori are important in endoscopy. To assess the accuracy of a new 5-min rapid urease test (UFT300, ABS Cernusco, sul Naviglio, Italy) compared with the 1-h Pyloritek (Serim Laboratories, Elkhart, IN) and the 24-h CLO test (Kimberly-Clark Ballard Medical Products, Roswell, GA), ...

journal_title：Internal and emergency medicine

authors： Vaira D,Gatta L,Ricci C,Perna F,Saracino I,Fiorini G,Castelli V,Holton J

更新日期：2010-02-01 00:00:00

abstract：INTRODUCTION:Oral anticoagulants (OAs) are significantly more effective than Aspirin in the prevention of cerebrovascular accidents among patients with atrial fibrillation (AF). Several studies, however, showed OAs to be widely underused in these patients. OBJECTIVE:To assess the appropriateness of antithrombotic ther...

journal_title：Internal and emergency medicine

authors： Ferro D,Loffredo L,Polimeni L,Violi F

更新日期：2007-03-01 00:00:00

abstract：:Patients with chronic obstructive pulmonary disease (COPD) have an increased cardiovascular morbidity and mortality. Flow-mediated (FMD) and nitrate-mediated dilatation (NMD) are considered non-invasive methods to assess endothelial function and surrogate markers of subclinical atherosclerosis. We performed a systemat...

journal_title：Internal and emergency medicine

authors： Ambrosino P,Lupoli R,Iervolino S,De Felice A,Pappone N,Storino A,Di Minno MND

更新日期：2017-09-01 00:00:00

abstract：:This study aims at evaluating the prevalence of left ventricular diastolic dysfunction in a group of 319 hypertensive patients with stage 3b-4-5 chronic kidney disease (according to Kidney Disease Improving Global Outcomes classification), compared with 216 patients with essential hypertension and normal renal functio...

journal_title：Internal and emergency medicine

authors： Nardi E,Mulè G,Nardi C,Geraci G,Giammanco A,Bentivegna R,Averna M

更新日期：2019-09-01 00:00:00

abstract：:The direct oral anticoagulants (DOACs) are drugs used in clinical practice since 2009 for the prevention of stroke or systemic embolism in non-valvular atrial fibrillation, and for the treatment and secondary prevention of venous thromboembolism. The four DOACs, including the three factor Xa inhibitors (rivaroxaban, a...

journal_title：Internal and emergency medicine

authors： Prisco D,Ageno W,Becattini C,D'Angelo A,Davì G,De Cristofaro R,Dentali F,Di Minno G,Falanga A,Gussoni G,Masotti L,Palareti G,Pignatelli P,Santi RM,Santilli F,Silingardi M,Tufano A,Violi F,SIMI (Italian Society of Inte

更新日期：2017-04-01 00:00:00

abstract：:Cirrhosis is characterized by a complex coagulation defect leading to the prolongation of the prothrombin and activated partial thromboplastin times (PT and APTT). Arbitrary PT cut-off values are still used as a yardstick to guide treatment with fresh-frozen plasma (FFP) or other pro-coagulant agents in patients under...

journal_title：Internal and emergency medicine

authors： Tripodi A,Chantarangkul V,Primignani M,Clerici M,Dell'era A,Aghemo A,Mannucci PM

更新日期：2012-04-01 00:00:00

abstract：:Prescription of non-vitamin K antagonist oral anticoagulants (NOACs) requires an assessment of renal function (RF) and the Cockcroft-Gault (CG) equation is traditionally recommended. The objective of the study was to evaluate the potential changes in NOACs management using different equations for estimating RF. In a p...

journal_title：Internal and emergency medicine

authors： Malavasi VL,Pettorelli D,Fantecchi E,Zoccali C,Laronga G,Trenti T,Lip GYH,Boriani G

更新日期：2018-10-01 00:00:00

abstract：:Up to 10% of all patients at the Emergency Department present for acute abdominal pain. The C-reactive protein (CRP) and white blood cell (WBC) are routinely determined as part of the workup of patients with abdominal pain. Three large prospective cohort studies comprising a total of 2961 adult patients with acute abd...

journal_title：Internal and emergency medicine

authors： Paolillo C,Spallino I,Gruppo di Autoformazione Metodologica (GrAM).

更新日期：2016-02-01 00:00:00

abstract：:The objective of this study is to evaluate potential drug-drug interactions (pDDIs) and risk factors for pDDIs in three phases of an acute coronary syndrome (ACS) treatment: from the point of first medical contact to the coronary angiography (first phase), after coronary angiography to the last day of hospitalization ...

journal_title：Internal and emergency medicine

authors： Pejčić AV,Janković SM,Davidović G

更新日期：2019-04-01 00:00:00

abstract：:Venous thromboembolism (VTE) is the third most common cardiovascular disease. Real-life data on the clinical presentation, risk factors, diagnosis, and treatment of VTE in Italy and Europe are required to optimize the management of this disease. The PREFER in VTE registry, a prospective non-interventional real-life st...

journal_title：Internal and emergency medicine

authors： Guercini F,Mommi V,Camporese G,Tonello C,Imberti D,Benedetti R,De Bartolomeo G,Di Lecce L,Romeo F,Agnelli G

更新日期：2016-12-01 00:00:00

abstract：:Septic arthritis (SA) is commonly associated with Staphylococcal or Streptococcal infections. Overtime, there has been a global increase in the distribution of antimicrobial resistance within both Gram-positive bacteria such as methicillin-resistant Staphylococcus aureus (MRSA) and Gram-negative bacteria such as exten...

journal_title：Internal and emergency medicine

authors： Ben-Chetrit E,Zamir A,Natsheh A,Nesher G,Wiener-Well Y,Breuer GS

更新日期：2020-06-01 00:00:00

abstract：:Genetic and acquired motor-neuron-disorders (MNDs) may undergo acute deterioration resulting in various emergency situations. This literature review aims at summarising and discussing current knowledge about emergencies in MNDs. Emergencies that have been reported in MND patients include: respiratory, bulbar, cardiac,...

journal_title：Internal and emergency medicine

authors： Finsterer J,Stöllberger C

更新日期：2017-08-01 00:00:00

abstract：:In chronic heart failure (CHF), neurohumoral systems, which help to maintain circulatory homeostasis, are maladaptive and responsible for disease progression and congestion in the long term. The activation of sympathetic hormones and renin-angiotensin-aldosterone system (RAAS), in addition to non-osmotic vasopressin r...

journal_title：Internal and emergency medicine

authors： Parrinello G,Torres D,Paterna S

更新日期：2011-10-01 00:00:00

abstract：:Cryoablation (CA) emerged as an alternative procedure to radiofrequency (RF). The aim of this study was to compare haemostatic system alterations in patients undergoing RF or CA for atrioventricular nodal reentrant tachycardia ablation. von Willebrand factor (vWF), spontaneous whole blood platelet aggregation, prothro...

journal_title：Internal and emergency medicine

authors： Pieragnoli P,Gori AM,Ricciardi G,Carrassa G,Checchi L,Michelucci A,Priora R,Cellai AP,Marcucci R,Padeletti L,Abbate R

更新日期：2014-12-01 00:00:00

abstract：:The purpose of this investigation was to investigate the association between first attempt success and intubation-related complications in the Intensive Care Unit after the widespread adoption of video laryngoscopy. We further sought to characterize and identify the predictors of complications that occur despite first...

journal_title：Internal and emergency medicine

authors： Hypes C,Sakles J,Joshi R,Greenberg J,Natt B,Malo J,Bloom J,Chopra H,Mosier J

更新日期：2017-12-01 00:00:00

abstract：:Our aim was to prospectively investigate the impact of Behçet's disease (BD), disease activity, and clinical and demographic characteristics on different aspects of quality of life (QoL) measured by the short-form (SF)-36 QoL scale. We administered the SF-36 to 37 consecutive BD patients in different moments of diseas...

journal_title：Internal and emergency medicine

authors： Fabiani C,Vitale A,Orlando I,Sota J,Capozzoli M,Franceschini R,Galeazzi M,Tosi GM,Frediani B,Cantarini L

更新日期：2017-10-01 00:00:00

abstract：:Transjugular intrahepatic portosystemic shunt (TIPS) represents a very effective treatment of complications of portal hypertension. Established indications to TIPS in cirrhotic patients include portal hypertensive bleeding and refractory ascites. Over the years additional indications have been proposed, such as the tr...

journal_title：Internal and emergency medicine

authors： Vizzutti F,Schepis F,Arena U,Fanelli F,Gitto S,Aspite S,Turco L,Dragoni G,Laffi G,Marra F

更新日期：2020-01-01 00:00:00

abstract：:In heart failure survival is closely related to functional capacity. Peak O2 consumption at cardiopulmonary exercise test (CPET) is considered the gold standard for the evaluation of exercise tolerance. Since >70% of patients with heart failure, usually elderly or with significant comorbidities, are referred to Depart...

journal_title：Internal and emergency medicine

authors： Rostagno C,Gensini GF

更新日期：2008-09-01 00:00:00

abstract：:There is a need for more information on the quality of life (QoL) in patients undergoing chemotherapy. We wanted to investigate the perception of health status in colon cancer patients before, 3 and 6 months after chemotherapy. A secondary purpose was to assess the different perceptions of QoL between men and women du...

journal_title：Internal and emergency medicine

authors： Domati F,Luppi G,Reggiani-Bonetti L,Zironi S,Depenni R,Fontana A,Gelsomino F,de Leon MP

更新日期：2015-06-01 00:00:00

abstract：:Coronavirus disease 2019 (COVID-19) is an emerging infectious disease which has had a rapid surge in cases and deaths since it is first documented in Wuhan, China, in December 2019. COVID-19 is caused by the Betacoronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 uses angiotensin-conve...

journal_title：Internal and emergency medicine

authors： Krishnan A,Hamilton JP,Alqahtani SA,A Woreta T

更新日期：2021-01-16 00:00:00

abstract：BACKGROUND AND AIMS:Patients with decompensated cirrhosis frequently require hospital admissions, which are associated with worse prognosis. The aim of this study was to analyze the effect of TIPS on the need for hospital care. Secondary objectives were to assess the clinical and biological impact of TIPS and to identi...

journal_title：Internal and emergency medicine

authors： Ballester MP,Lluch P,Gómez C,Capilla M,Tosca J,Martí-Aguado D,Guijarro J,Mínguez M

更新日期：2021-01-05 00:00:00

abstract：OBJECTIVE:Current guidelines for evaluation of syncope recommend that in the absence of objective focal neurologic findings, head computed tomography (HCT) may not be necessary. Compliance with this recommendation is highly variable, which may be due in part to the lack of currently available evidence. We undertook the...

journal_title：Internal and emergency medicine

authors： Goyal N,Donnino MW,Vachhani R,Bajwa R,Ahmad T,Otero R

更新日期：2006-01-01 00:00:00

abstract：:Inconsistent findings in the studies have been observed concerning the higher dose of statins use in the acute phase of ischemic stroke and transient ischemic attack (TIA). Therefore, we performed a systematic review to assess this issue. A computerized literature search in PubMed, Cochrane Library databases, and EMBA...

journal_title：Internal and emergency medicine

authors： Fang JX,Wang EQ,Wang W,Liu Y,Cheng G

更新日期：2017-08-01 00:00:00

abstract：:Despite advances in diagnosis, antimicrobial therapy and supportive care modalities, community-acquired pneumonia (CAP) remains an important cause of morbidity and mortality, especially in patients who require hospitalization. Elderly patients with poor functional status are characterized by a higher risk of developin...

journal_title：Internal and emergency medicine

authors： Falcone M,Blasi F,Menichetti F,Pea F,Violi F

更新日期：2012-10-01 00:00:00

abstract：:Iron deficiency anemia (IDA) is one of the most common complications of inflammatory bowel disease (IBD). We planned a prospective study to address tolerability and efficacy of sucrosomial iron, a new oral formulation of ferric pyrophosphate, in IBD patients. Thirty patients with a confirmed diagnosis of Crohn's Disea...

journal_title：Internal and emergency medicine

authors： Abbati G,Incerti F,Boarini C,Pileri F,Bocchi D,Ventura P,Buzzetti E,Pietrangelo A

更新日期：2019-04-01 00:00:00

abstract：:Data on the presence of subclinical fibrosis across multiple organs in patients with idiopathic lung fibrosis (IPF) are lacking. Our study aimed at investigating through hepatic transient elastography (HTE) the prevalence and clinical impact of subclinical liver fibrosis in a cohort of patients with IPF. Patients refe...

journal_title：Internal and emergency medicine

authors： Cocconcelli E,Tonelli R,Abbati G,Marchioni A,Castaniere I,Pelizzaro F,Russo FP,Vegetti A,Balestro E,Pietrangelo A,Richeldi L,Luppi F,Spagnolo P,Clini E,Cerri S

更新日期：2020-05-25 00:00:00

abstract：:A difficult airway may lead to hypoxia and brain damage. The WEI Nasal Jet Tube (WNJ) is a new nasal pharyngeal tube that applies supraglottic jet oxygenation and ventilation (SJOV) for patients during tracheal intubation without the need for mask ventilation. We evaluated the effectiveness and safety of SJOV-assisted...

journal_title：Internal and emergency medicine

authors： Wu C,Wei J,Cen Q,Sha X,Cai Q,Ma W,Cao Y

更新日期：2017-08-01 00:00:00

abstract：:Predictors of short-term readmission after ischemic stroke have been previously identified, but few studies analyzed predictors of long-term readmission, namely early imaging findings and treatment with intravenous thrombolysis (IVT). To characterize predictors of hospital readmission during the first year after hospi...

journal_title：Internal and emergency medicine

authors： Leitão A,Brito A,Pinho J,Alves JN,Costa R,Amorim JM,Ribeiro M,Pinho I,Ferreira C

更新日期：2017-02-01 00:00:00