当前位置： SCI文献检索 > TRANSPLANTATION PROCEEDINGS期刊下所有文献 > Factors associated with persistent thrombocytopenia after liver transplantation.

Factors associated with persistent thrombocytopenia after liver transplantation.

Abstract：

BACKGROUND:Thrombocytopenia typically resolves with resolution of portal hypertension after liver transplantation (LT) but persists in some patients. Identifying risk factors associated with persistent post- LT thrombocytopenia may provide important information about its pathogenesis. METHODS:Cirrhotic adults with platelet levels of <150,000 mu/L at the time of LT and followed at least 1 year were studied. A retrospective analysis of lab values, radiologic spleen index (SI), and donor data using nonparametric methods was performed to characterize patients having persistent thrombocytopenia, defined as persistently low platelet levels at 3 and 12 months after LT. RESULTS:One hundred patients were studied: mean age 55 y (range 23-75 y); platelet count at LT 62,000/microL (range 14,000- 148,000/microL; mean total bilirubin 2.6 mg/dL; mean Mayo end-stage liver disease score 29; SI 1,476 (range 347-4,843 mL; normal 120-480 mL). Platelet count at 3 and 12 months after LT correlated with SI (r = -0.41 and -0.54; P < .001). Fifty-seven patients had persistent thrombocytopenia. Compared with patients whose platelet levels normalized by month 3 or 12, they had higher SI and lower platelet count before LT (P < .001). The SI and platelet levels at the time of LT were independent predictive factors for platelet levels at 3 and 12 months after LT (P < .001). CONCLUSIONS:High SI and low platelet count at the time of LT are associated with persistent thrombocytopenia after LT. They are also independent predictive factors of platelet levels at 3 and 12 months after LT. This suggests that patients may have persistent thrombocytopenia after LT owing to persistence of some degree of hypersplenism and incomplete resolution of splenomegaly.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Stanca CM,Fiel MI,Aledort L,Cohen E,del Rio Martin J,Schiano TD

doi

10.1016/j.transproceed.2010.02.075

subject

Has Abstract

pub_date

2010-06-01 00:00:00

pages

1769-73

issue

5

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(10)00523-3

journal_volume

42

pub_type

杂志文章

相关文献

TRANSPLANTATION PROCEEDINGS文献大全
  • Switching from mycophenolate mofetil to enteric-coated mycophenolate sodium in liver transplant patients with gastrointestinal complications.

    abstract：OBJECTIVE:Our aim was to safely and effectively reduce adverse gastrointestinal (GI) events resulting from the use of mycophenolate mofetil (MMF) in liver transplant patients by switching to enteric-coated mycophenolate sodium (EC-MPS). PATIENTS AND METHODS:We studied 19 patients on maintenance therapy presenting with...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2009.06.004

    authors： Barrera-Pulido L,Alamo-Martínez JM,Marín-Gómez LM,Suárez-Artacho G,Bernal-Bellido C,Domínguez-Usero D,Tallón-Aguilar L,Pareja-Ciuró F,Sousa-Martín JM,García-González I,Gómez-Bravo MA

    更新日期：2009-07-01 00:00:00

  • "Real-time" assessment of human islet preparations with confocal live cell imaging.

    abstract：:Pancreatic islet cell transplantation is a promising approach to restoring normoglycemia in diabetic patients. The outcome of islet transplantation is uncertain for two reasons: The quality of isolated islets is still poorly defined and the functional potential of transplanted islets is difficult to predict. Therefore...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2005.09.076

    authors： Hermann M,Pirkebner D,Draxl A,Margreiter R,Hengster P

    更新日期：2005-10-01 00:00:00

  • Association of the A1936G (rs203462) of A-kinase anchoring protein 10 polymorphisms with QT interval prolongation during kidney transplantation.

    abstract：INTRODUCTION:The purpose of this study was to investigate whether the polymorphism in the kinase-binding domain of A-kinase anchoring protein 10 (AKAP10) was related to the risk of occurrence of potentially dangerous arrhythmias during kidney transplant. METHODS:We performed this prospective observational study with a...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2009.09.016

    authors： Zukowski M,Bohatyrewicz R,Biernawska J,Kotfis K,Knap R,Kaczmarczyk M,Ciechanowicz A,Binczak A,Brykczyński M

    更新日期：2009-10-01 00:00:00

  • Changes in Tumor Markers and Their Implications in Selecting Liver Transplantation for Patients With Hepatocellular Carcinoma.

    abstract：BACKGROUND AND AIM:It has been suggested that tumor markers can provide additional information over tumor size and number-based liver transplantation (LT) criteria. We aimed to assess if changes in tumor markers are associated with the risk of tumor recurrence after LT for hepatocellular carcinoma (HCC) who received lo...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2020.01.037

    authors： Song BG,Sinn DH,Kang W,Gwak GY,Paik YH,Choi MS,Lee JH,Koh KC,Paik SW,Kim JM,Joh JW,Choi GS

    更新日期：2020-04-01 00:00:00

  • Organ donation: acceptance and refusal among users of the public health system from Brazil.

    abstract：:The present study sought to identify the perception of a given group of users of the Brazilian Public Health System (Sistema Unico de Saúde) regarding organ donation and to implement an educational policy. Structured interviews were conducted with the aim of describing the profile of donor and nondonor subjects, the i...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2008.03.011

    authors： Sasso-Mendes KD,Curvo PA,Silveira RC,Galvão CM

    更新日期：2008-04-01 00:00:00

  • C0h/C2h monitoring of the pharmacodynamics of cyclosporin plus mycophenolate mofetil in human heart transplant recipients.

    abstract：UNLABELLED:Pharmacokinetic (PK) parameters like C2h have improved efficacy of immunosuppressive therapy. However, drug interactions, toxicities, and individual differences to drug effects still remain challenging. Therefore, this study was designed to assess pharmacodynamic (PD) effects of the combination cyclosporin (...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2004.12.116

    authors： Barten MJ,Rahmel A,Garbade J,Richter M,Bittner HB,Dhein S,Mohr FW,Gummert JF

    更新日期：2005-03-01 00:00:00

  • Hypothermic Circulatory Arrest in Cardiac Transplantation.

    abstract：PURPOSE:Infrequently, hypothermic circulatory arrest (HCA) must be used during cardiac transplantation. Such cases may include concomitant aortic arch surgery, explantation of ventricular assist devices with outflow grafts or pseudoaneurysms closely abutting the sternum, and other scenarios for which dense mediastinal ...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2015.07.039

    authors： Lima B,Chamogeorgakis T,MacHannaford JC,Gonzalez-Stawinski GV

    更新日期：2015-11-01 00:00:00

  • Results of liver transplantation with donors older than 70 years: a case-control study.

    abstract：:Older donors are a growing part of the total pool but no definite consensus exists on the age limit for their acceptance. This retrospective case-control unicenter study compared the outcomes of 72 orthotopic liver transplantations (OLTs) from April 1990 to April 2010 using donors older than 70 years versus 738 chrono...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2011.05.016

    authors： Álamo JM,Barrera L,Marín LM,Bernal C,Suárez G,Serrano J,Gómez MA,Padillo FJ

    更新日期：2011-07-01 00:00:00

  • Pain affects health-related quality of life in kidney transplant recipients.

    abstract：BACKGROUND:Chronic pain is prevalent in end-stage renal disease patients undergoing chronic hemodialysis. We do not fully know the intensity of chronic pain experienced by kidney recipients in comparison to those on chronic hemodialysis and healthy controls. Moreover, the effect of chronic pain on kidney recipients' he...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2007.03.004

    authors： Nourbala MH,Hollisaaz MT,Nasiri M,Bahaeloo-Horeh S,Najafi M,Araghizadeh H,Rezaie Y,Lak M

    更新日期：2007-05-01 00:00:00

  • Compensatory Hypertrophy After Living Donor Nephrectomy.

    abstract：BACKGROUND:Previous studies have shown that kidney volume enhances the estimation of glomerular filtration rate (eGFR) in kidney donors. This study aimed to describe the phenomenon of compensatory hypertrophy after donor nephrectomy as measured on computerized tomographic (CT) scans. METHODS:An institutional Domain Sp...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2015.12.082

    authors： Chen KW,Wu MW,Chen Z,Tai BC,Goh YS,Lata R,Vathsala A,Tiong HY

    更新日期：2016-04-01 00:00:00

  • Deceased Donor Liver Transplantation in India in the COVID-19 Era: Current Scenario and Future Perspectives.

    abstract：:Coronavirus disease 2019 (COVID-19) has been recently declared a global pandemic. As of June 5, 2020, over 75,000 cases have been reported with nearly 2500 deaths in India alone. COVID-19 has severely impacted deceased donor liver transplant (DDLT) programs throughout the world. Acceptance of deceased liver donors has...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2020.06.004

    authors： Pahari H,Shellagi N,Nath B

    更新日期：2020-11-01 00:00:00

  • Transfection of human hepatocyte growth factor gene inhibits advancing pulmonary arterial hypertension induced by shunt flow in a rabbit model.

    abstract：:We investigated gene transfer with human hepatocyte growth factor (HGF) to suppress pulmonary arterial hypertension (PAH) produced by an arteriovenous shunt in a rabbit model. The rabbit model of advanced PAH was used to show that HGF targets pulmonary arteriolar endothelial cells and inhibits disease progression. In ...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2012.07.158

    authors： Liu R,Wu S,Cao G,Wang W,Liu K,Wu S

    更新日期：2013-03-01 00:00:00

  • Early urine output predicts graft survival after kidney transplantation.

    abstract：BACKGROUND:In kidney transplantations, the identification of early postoperative parameters with high predictive power for the development of late allograft dysfunction has important implications for clinical practice. This study sought to determine these parameters in a single-center cohort. METHODS:We studied 82 dec...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2010.03.088

    authors： Lai Q,Pretagostini R,Poli L,Levi Sandri GB,Melandro F,Grieco M,Spoletini G,Rossi M,Berloco PB

    更新日期：2010-05-01 00:00:00

  • Family Function in Pediatric Liver Transplant Recipients Residing In a Developing Country.

    abstract：BACKGROUND:Pediatric liver transplantation (LT) can affect recipients' family function; however, inconsistent results between studies exist, and data from developing nations are sparse. We aimed to evaluate family function and identify factors associated with suboptimal function in pediatric LT recipients. METHODS:A c...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2020.01.035

    authors： Butsriphum N,Getsuwan S,Prabpram W,Chuthapisith J,Tanpowpong P,Lertudomphonwanit C,Treepongkaruna S

    更新日期：2020-04-01 00:00:00

  • Intrabronchial instillation of amphotericin B lipid complex: a case report.

    abstract：OBJECTIVE:We sought to present our results of topical intrabronchial installation of amphotericin B lipid complex (AmpB lipid). PATIENT AND METHODS:A deposit of fungal material was observed in a bilateral lung transplant recipient who experienced stenosis of the left anastomosis and have been fitted with a double endo...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2009.06.017

    authors： Morales P,Galán G,Sanmartín E,Monte E,Tarrazona V,Santos M

    更新日期：2009-07-01 00:00:00

  • Monitoring of intrasplenic hepatocyte transplantation for acute-on-chronic liver failure: a prospective five-year follow-up study.

    abstract：BACKGROUND:Acute-on-chronic liver failure (ACLF) is defined as an acute deterioration of chronic liver disease. Intrasplenic hepatocyte transplantation is increasingly recognized as a treatment for liver failure and genetic metabolic liver diseases. We describe our experience of intrasplenic hepatocyte transplantation ...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2013.10.042

    authors： Wang F,Zhou L,Ma X,Ma W,Wang C,Lu Y,Chen Y,An L,An W,Yang Y

    更新日期：2014-01-01 00:00:00

  • Comparison of Incidence and Risk of Depression in Recipients of Renal Transplantation and Patients Undergoing Hemodialysis in China.

    abstract：AIM:To investigate depressive symptoms in recipients of renal transplantation (RTx) compared with patients undergoing hemodialysis (HD) in China. METHODS:Forty-two Chinese recipients of transplant and 42 Chinese patients on hemodialysis were randomly selected from 2011 to 2012. These 2 groups were assessed with the va...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2018.07.029

    authors： Wang Y,Bu T,Yan P,Yao H

    更新日期：2018-12-01 00:00:00

  • Mycobacterium abscessus infection in transplant recipients.

    abstract：BACKGROUND:Mycobacterium abscessus is a ubiquitous, rapidly growing mycobacterium that colonizes organic surfaces. It is a potential pathogen, especially in immunosuppressed patients, including transplant recipients in whom disease can range from localized cutaneous lesions to disseminated infections. The purpose of th...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2010.08.004

    authors： Morales P,Gil A,Santos M

    更新日期：2010-10-01 00:00:00

  • A logistic regression model for predicting health-related quality of life in kidney transplant recipients.

    abstract：BACKGROUND:To develop a logistic regression model capable of predicting health-related quality of life (HRQOL) among kidney transplant recipients and determine its accuracy. METHODS:Three groups of patients were selected: 70 healthy controls, 136 kidney transplant patients as a derivation set, and another 110 kidney t...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2007.04.004

    authors： Khedmat H,Karami GR,Pourfarziani V,Assari S,Rezailashkajani M,Naghizadeh MM

    更新日期：2007-05-01 00:00:00

  • Solid Organ Transplantation in HIV+ Recipients: Italian Experience.

    abstract：INTRODUCTION:According to current estimates, there are about 540,000 patients who are infected with HIV in Western Europe, of which about 3100 are potential candidates for organ transplantation. In Italy, there are currently 85 HIV patients on the transplant list. METHODS:Organ transplantation activity in HIV recipien...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2015.12.049

    authors： Morabito V,Grossi P,Lombardini L,Ricci A,Trapani S,Peritore D,Gaeta A,Ballanti D,Del Sordo E,Rizzato L,Nanni Costa A

    更新日期：2016-03-01 00:00:00

  • Transplantation of organs: natural limitations, possible solutions--a UK perspective.

    abstract：:While the outcome following organ transplantation in the United Kingdom has never been better, the waiting list has never been longer and the organ shortage is now the most pressing issue. UK Transplant has invested in four initiatives to promote donor and transplant numbers: coordinating the coordinators, establishin...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/s0041-1345(03)00127-1

    authors： Rudge CJ

    更新日期：2003-05-01 00:00:00

  • The new body mass index system in predicting renal graft outcomes.

    abstract：BACKGROUND:Obesity has been related to poor renal graft function. The aim of this study was to compare the long-term graft outcomes of living-related kidney recipients regarding donor-to-recipient body mass index (BMI) parameters using the old Quetelet BMI formula and the new Trefethen BMI formula. METHODS:From Novemb...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2013.12.029

    authors： Wang HH,Lin KJ,Chu SH,Chiang YJ,Liu KL,Hsieh CY

    更新日期：2014-01-01 00:00:00

  • Combination protocols for prevention of CMV disease in the high risk transplant patient.

    abstract：:Overall, the results seen in this study are encouraging. In this high-risk group of patients where the expected disease rate would normally be at least 55% to 60% without prophylaxis, a combination protocol of GCV, ACV, and CMVIG limited the rate of disease to 19%. When disease occurred, it was generally mild and easi...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章,评审

    doi：

    authors： Martin M

    更新日期：1996-12-01 00:00:00

  • Anatomical classification of the peripheral right hepatic duct: early identification of a preventable source of morbidity and mortality in adult live donor liver transplantation.

    abstract：INTRODUCTION:The purpose of this study was to determine the impact of our classification on right graft adult live donor liver transplantation (ALDLT) outcomes. METHODS:Three-dimensional computed tomography (CT) reconstructions were used to classify the hilar and sectorial biliary anatomy of 71 consecutive live liver ...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2008.08.044

    authors： Radtke A,Sgourakis G,Sotiropoulos GC,Molmenti EP,Fouzas I,Schroeder T,Saner FH,Schenk A,Beckebaum S,Malagó M,Lang H

    更新日期：2008-11-01 00:00:00

  • Vascular complications in renal transplantation: a single-center experience in 1367 renal transplantations and review of the literature.

    abstract：:Renal transplantation is the treatment of choice for end-stage renal disease. Vascular complications in renal transplantation are not uncommon and may often lead to allograft loss. The most common vascular complications are transplant renal artery stenosis, transplant renal artery thrombosis, transplant renal vein thr...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2009.02.077

    authors： Dimitroulis D,Bokos J,Zavos G,Nikiteas N,Karidis NP,Katsaronis P,Kostakis A

    更新日期：2009-06-01 00:00:00

  • Cytomegalovirus disease after kidney transplantation: clues to accurate diagnosis.

    abstract：BACKGROUND:The clinical diagnosis of cytomegalovirus (CMV) disease after kidney transplantation is often not accurate. We evaluated the factors associated with a correct diagnosis of CMV disease in these patients. MATERIALS AND METHODS:This retrospective study of all renal transplant patients between 2004 and 2005 wit...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2007.03.087

    authors： Nemati E,Eizadi M,Lankarani MM,Kardavani B,Khoddami-Vishteh HR,Kalantar E,Lesan-Pezeshki M,Khedmat H,Saadat AR

    更新日期：2007-05-01 00:00:00

  • Effect of Different Rituximab Doses on B Cell Count, Anti-A/B Antibody Titer, Graft Function, and Infectious Complications in ABO-Incompatible Renal Transplantation: A Prospective Study.

    abstract：BACKGROUND:ABO-incompatible kidney transplantation (ABOiKT) has been accepted as a viable and cost-effective modality with outcomes comparable to ABO-compatible transplants, but there is a concern regarding higher infectious complications in ABOiKT because of the heightened immunosuppression. The desensitization protoc...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2020.10.008

    authors： Thukral S,Shinde N,Ray DS

    更新日期：2020-12-02 00:00:00

  • Time-related changes in the incidence, severity, and clinical outcome of hepatic veno-occlusive disease in hematopoietic stem cell transplantation patients during the past 10 years.

    abstract：:Veno-occlusive disease (VOD) of the liver occurs in 10% to 50% of patients after hematopoietic stem cell transplantation (HSCT), ranging from a mild reversible disease to a fulminant course with a mortality rate close to 100%. We retrospectively evaluated the clinical signs, diagnosis, prognosis, therapy, and outcome ...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2005.03.025

    authors： Kalayoglu-Besisik S,Yenerel MN,Caliskan Y,Ozturk S,Besisik F,Sargin D

    更新日期：2005-06-01 00:00:00

  • Ethical considerations in the early composite tissue allograft experience: a review of the Louisville Ethics Program.

    abstract：:This paper reviews the formulation and evolution of the ethical component in one of the earliest clinical composite tissue allograft (CTA) programs, the hand transplantation program in Louisville, Kentucky, USA. The purpose was to derive lessons and define principles to give guidance for future programs and introducti...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章,评审

    doi：10.1016/j.transproceed.2004.12.179

    authors： Tobin GR,Breidenbach WC,Klapheke MM,Bentley FR,Pidwell DJ,Simmons PD

    更新日期：2005-03-01 00:00:00

  • A new kidney allocation policy in Chile: computer-based simulations.

    abstract：INTRODUCTION:Kidney allocation should reach a balance between equity and efficiency. In Chile kidneys are allocated based on ABO matching, first to medical priorities and then according to a point scheme considering human leukocyte antigen (HLA) match (60%), waiting list time (20%), and panel-reactive antibodies (PRA; ...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2013.01.012

    authors： Domínguez J,Harrison R,Atal R,Muñoz F

    更新日期：2013-05-01 00:00:00